Lista de obras - Joseph D Turner - Dominio Público Uruguay

<i>Wolbachia</i> depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment

artículo científico publicado en 2022

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

artículo científico publicado en 2014

A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection.

artículo científico publicado en 2006

AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.

artículo científico publicado en 2017

Blood flukes exploit Peyer's Patch lymphoid tissue to facilitate transmission from the mammalian host

artículo científico publicado en 2012

Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

artículo científico publicado en 2019

CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection

artículo científico publicado en 2011

Circulating CD14brightCD16+ 'intermediate' monocytes exhibit enhanced parasite pattern recognition in human helminth infection

artículo científico publicado en 2014

Comparison of immune responses to Loa loa stage-specific antigen extracts in Loa loa-exposed BALB/c mice upon clearance of infection

artículo científico publicado en 2020

Cytokine response profiles predict species-specific infection patterns in human GI nematodes

article

Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing

artículo científico publicado en 2019

Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

scientific article published on 28 February 2019

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections

scientific article published on 01 May 2019

Enhanced pro-inflammatory cytokine responses following Toll-like-receptor ligation in Schistosoma haematobium-infected schoolchildren from rural Gabon

artículo científico publicado en 2011

Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling

artículo científico publicado en 2020

Evaluation of in vitro culture systems for the maintenance of microfilariae and infective larvae of Loa loa.

artículo científico publicado en 2018

Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells

artículo científico publicado en 2009

Gastrointestinal nematode infection is associated with variation in innate immune responsiveness

artículo científico publicado en 2005

Generation of Loa loa infective larvae by experimental infection of the vector, Chrysops silacea

scientific article published on 17 August 2020

Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro

artículo científico publicado en 2014

Implementation of test-and-treat with doxycycline and temephos ground larviciding as alternative strategies for accelerating onchocerciasis elimination in an area of loiasis co-endemicity: the COUNTDOWN consortium multi-disciplinary study protocol

scientific article published on 04 December 2019

In vitro maintenance of Mansonella perstans microfilariae and its relevance for drug screening

scientific article published on 30 September 2019

In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis

scientific article published on 27 January 2020

In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae

artículo científico publicado en 2019

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

artículo científico publicado en 2019

Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness

artículo científico publicado en 2008

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

artículo científico publicado en 2018

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

artículo científico publicado en 2016

Mouse models of Loa loa

artículo científico publicado en 2019

Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells.

artículo científico publicado en 2011

Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?

scientific article published on 15 February 2020

Onchocerca ochengi male worms implanted in SCID mice and Gerbil: Relationship between microfilaridermia status of cows, nodular worm viability and fertility and worm survival in the rodents

artículo científico publicado en 2021

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

artículo científico publicado en 2019

Schistosome infection is associated with enhanced whole-blood IL-10 secretion in response to cercarial excretory/secretory products

article

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

artículo científico publicado en 2017

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models

artículo científico publicado en 2019

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

artículo científico publicado en 2019

T helper cell type 2 responsiveness predicts future susceptibility to gastrointestinal nematodes in humans.

artículo científico publicado en 2004

Th2 Cytokines Are Associated with Reduced Worm Burdens in a Human Intestinal Helminth Infection

artículo científico publicado en 2003

The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production.

artículo científico publicado en 2011

The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models.

artículo científico publicado en 2016

Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models.

artículo científico publicado en 2018

Why onchocerciasis transmission persists after 15 annual ivermectin mass drug administrations in South-West Cameroon

artículo científico publicado en 2021

Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis.

scientific article published on 18 October 2016

Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.

artículo científico publicado en 2009

Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness).

artículo científico publicado en 2004

Lista de obras de Joseph D Turner

<i>Wolbachia</i> depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection.

AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.

Blood flukes exploit Peyer's Patch lymphoid tissue to facilitate transmission from the mammalian host

Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection

Circulating CD14brightCD16+ 'intermediate' monocytes exhibit enhanced parasite pattern recognition in human helminth infection

Comparison of immune responses to Loa loa stage-specific antigen extracts in Loa loa-exposed BALB/c mice upon clearance of infection

Cytokine response profiles predict species-specific infection patterns in human GI nematodes

Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing

Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections

Enhanced pro-inflammatory cytokine responses following Toll-like-receptor ligation in Schistosoma haematobium-infected schoolchildren from rural Gabon

Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling

Evaluation of in vitro culture systems for the maintenance of microfilariae and infective larvae of Loa loa.

Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells

Gastrointestinal nematode infection is associated with variation in innate immune responsiveness

Generation of Loa loa infective larvae by experimental infection of the vector, Chrysops silacea

Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro

Implementation of test-and-treat with doxycycline and temephos ground larviciding as alternative strategies for accelerating onchocerciasis elimination in an area of loiasis co-endemicity: the COUNTDOWN consortium multi-disciplinary study protocol

In vitro maintenance of Mansonella perstans microfilariae and its relevance for drug screening

In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis

In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

Mouse models of Loa loa

Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells.

Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?

Onchocerca ochengi male worms implanted in SCID mice and Gerbil: Relationship between microfilaridermia status of cows, nodular worm viability and fertility and worm survival in the rodents

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

Schistosome infection is associated with enhanced whole-blood IL-10 secretion in response to cercarial excretory/secretory products

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

T helper cell type 2 responsiveness predicts future susceptibility to gastrointestinal nematodes in humans.

Th2 Cytokines Are Associated with Reduced Worm Burdens in a Human Intestinal Helminth Infection

The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production.

The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models.

Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models.

Why onchocerciasis transmission persists after 15 annual ivermectin mass drug administrations in South-West Cameroon

Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis.

Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.

Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness).