Lista de obras - John R Mascola - Dominio Público Uruguay

1272. Feasibility and Successful Enrollment in Proof-of-Concept Trials to Assess Safety and Efficacy of a Broadly Neutralizing Monoclonal Antibody, VRC01, to Prevent HIV-1 Acquisitionin in Uninfected Individuals

454 pyrosequencing and bioinformatics analysis of the lineage of the broad and potent gp41-directed antibody 10e8.

artículo científico publicado en 2012

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2015

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

scientific article published on 01 September 2019

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

artículo científico publicado en 2018

A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial

artículo científico publicado en 2008

A Virus-Like Particle Vaccine Elicits Broad Neutralizing Antibody Responses in Humans to All Chikungunya Virus Genotypes

artículo científico publicado en 2016

A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults during a Phase 1 Clinical Trial

artículo científico publicado en 2007

A West Nile Virus DNA Vaccine Utilizing a Modified Promoter Induces Neutralizing Antibody in Younger and Older Healthy Adults in a Phase I Clinical Trial ⬇️

artículo científico publicado el 11 de marzo de 2011

A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice

artículo científico publicado en 2022

A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling

artículo científico publicado en 2013

A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates

artículo científico publicado en 2005

A human monoclonal antibody specific for the V3 loop of HIV type 1 clade E cross-reacts with other HIV type 1 clades.

artículo científico publicado en 1998

A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B.

artículo científico publicado en 1995

A method for identification of HIV gp140 binding memory B cells in human blood

artículo científico publicado en 2008

A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike

artículo científico publicado en 2020

A phase I/II trial of HIV SF2 gp120/MF59 vaccine in seronegative Thais

article

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike alone

artículo científico publicado en 2020

A proof of concept for structure-based vaccine design targeting RSV in humans

scientific article published on 01 August 2019

A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults

artículo científico publicado en 2010

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.

artículo científico publicado en 2012

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

artículo científico publicado en 2012

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

scientific article published on 27 April 2016

A strategic approach to COVID-19 vaccine R&D

artículo científico publicado en 2020

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

scientific article published on 01 May 2019

A1 The role of virus-antibody co-evolution in the development of a V3-glycan-directed HIV-1 broadly neutralizing antibody lineage

AIDS vaccines. Are we ready for human efficacy trials?

scientific article published on 01 August 1994

Accumulation of follicular CD8+ T cells in pathogenic SIV infection.

artículo científico publicado en 2018

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

scientific article published on 11 October 2019

Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin

artículo científico publicado en 2019

Activation and lysis of human CD4 cells latently infected with HIV-1

artículo científico publicado en 2015

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

artículo científico publicado en 2017

An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.

artículo científico publicado en 2016

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

artículo científico publicado en 2014

An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial

artículo científico publicado en 2017

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

artículo científico publicado en 2020

Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial

artículo científico publicado en 2013

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

artículo científico publicado en 2011

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

artículo científico publicado en 2015

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

artículo científico publicado en 2008

Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles

artículo científico publicado en 2007

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

artículo científico publicado en 2005

Anti-HIV B Cell lines as candidate vaccine biosensors

artículo científico publicado en 2012

Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site

artículo científico publicado en 2008

Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline

artículo científico publicado en 2014

Antibodies with specificity to native gp120 and neutralization activity against primary human immunodeficiency virus type 1 isolates elicited by immunization with oligomeric gp160.

artículo científico publicado en 1997

Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

scientific article published on 01 November 2019

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

artículo científico publicado en 2019

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

scholarly article by Nicole Doria-Rose published in 2021

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

artículo científico publicado en 2021

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

Antibody responses to envelope glycoproteins in HIV-1 infection

artículo científico publicado en 2015

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

artículo científico publicado en 2009

Antibody-Dependent Cell-Mediated Cytotoxicity in Simian Immunodeficiency Virus-Infected Rhesus Monkeys ⬇️

artículo científico publicado el 18 de mayo de 2011

Antibody-Dependent Cell-Mediated Viral Inhibition Emerges after Simian Immunodeficiency Virus SIVmac251 Infection of Rhesus Monkeys Coincident with gp140-Binding Antibodies and Is Effective against Neutralization-Resistant Viruses ⬇️

artículo científico publicado el 30 de marzo de 2011

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding ⬇️

artículo científico publicado el 6 de junio de 2012

Antibody-based HIV-1 vaccines: recent developments and future directions

artículo científico publicado en 2007

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

artículo científico publicado en 2017

Antigen detection in neutralization assays: high levels of interfering anti-p24 antibodies in some plasma

scientific article published on 01 December 1993

As antibody findings mount, what comes next? Interview by Kristen Jill Kresge and Regina McEnery

artículo científico publicado el 1 de enero de 2011

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

scientific article published on 26 November 2020

Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial

artículo científico publicado en 2019

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

Author Correction: Next-generation influenza vaccines: opportunities and challenges

artículo científico publicado en 2020

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

artículo científico publicado en 2008

BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses

artículo científico publicado en 2012

Basis and Statistical Design of the Passive HIV-1 Antibody Mediated Prevention (AMP) Test-of-Concept Efficacy Trials

artículo científico publicado en 2017

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus

artículo científico publicado en 2005

Biochemically Defined HIV-1 Envelope Glycoprotein Variant Immunogens Display Differential Binding and Neutralizing Specificities to the CD4-binding Site ⬇️

artículo científico publicado el 13 de diciembre de 2011

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

artículo científico publicado en 2015

Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens

artículo científico publicado en 2012

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

artículo científico publicado en 2009

Brief Report: Prediction of Serum HIV-1 Neutralization Titers After Passive Administration of VRC01

scientific article published on 01 April 2020

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

artículo científico publicado en 2007

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

artículo científico publicado en 2019

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

artículo científico publicado en 2012

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

artículo científico publicado en 2009

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

artículo científico publicado en 2009

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype ⬇️

artículo científico publicado en 2016

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

artículo científico publicado en 2015

Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning ⬇️

artículo científico publicado el 1 de septiembre de 2013

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

artículo científico publicado en 2017

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

artículo científico publicado en 2014

CD8β Depletion Does Not Prevent Control of Viral Replication or Protection from Challenge in Macaques Chronically Infected with a Live Attenuated Simian Immunodeficiency Virus

scientific article published on 17 July 2019

Canarypox virus-induced maturation of dendritic cells is mediated by apoptotic cell death and tumor necrosis factor alpha secretion

artículo científico publicado en 2000

Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies

artículo científico publicado en 2003

Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.

artículo científico publicado en 2007

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

article

Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus

scientific article published on 08 May 2020

Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants

artículo científico publicado en 2006

Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors.

artículo científico publicado en 2018

Characterization of complete HIV type 1 genomes from non-B subtype infections in U.S. military personnel

artículo científico publicado en 2005

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity ⬇️

artículo científico publicado en 2007

Characterization of the Neutralizing Antibody Response in a Case of Genetically Linked HIV Superinfection

article

Characterizing the fitness cost of viral escape from the HIV-1 broadly neutralizing monoclonal antibody VRC01

article

Chimpanzee Adenovirus Vector Ebola Vaccine — Preliminary Report

artículo científico publicado en 2014

Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

artículo científico publicado en 2014

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

artículo científico publicado en 2013

Combination recombinant simian or chimpanzee adenoviral vectors for vaccine development

artículo científico publicado en 2015

Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model

artículo científico publicado en 2005

Comparison of adjuvants to optimize influenza neutralizing antibody responses

scientific article published on 05 September 2019

Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

article

Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

article

Construction and biological characterization of infectious molecular clones of HIV-1 subtypes B and E (CRF01_AE) generated by the polymerase chain reaction

artículo científico publicado en 2000

Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor

artículo científico publicado en 2020

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

artículo científico publicado en 2014

Correction for Acharya et al., Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

article

Correction for Chakrabarti et al., Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates.

artículo científico publicado en 2014

Correction for Hraber et al., "Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments".

artículo científico publicado en 2017

Correction for Ingale et al., Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies

artículo científico publicado en 2015

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

article

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 02 December 2019

Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

artículo científico publicado en 2016

Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early-stage infection

artículo científico publicado en 1998

Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope

artículo científico publicado en 2006

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies

artículo científico publicado en 2011

Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens

artículo científico publicado en 2008

Cross-subtype neutralizing antibodies induced in baboons by a subtype E gp120 immunogen based on an R5 primary human immunodeficiency virus type 1 envelope

artículo científico publicado en 1999

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

artículo científico publicado en 2020

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

scientific article published on 11 December 2019

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

artículo científico publicado en 2011

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

artículo científico publicado en 2010

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

artículo científico publicado en 2017

DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial ⬇️

artículo científico publicado el 8 de abril de 2013

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials ⬇️

artículo científico publicado el 3 de octubre de 2011

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts

artículo científico publicado en 2013

Deep sequencing with longitudinal sampling of a VRC01-like-antibody response in a chronically infected individual

artículo científico publicado en 2012

Defining the Protective Antibody Response for HIV-1 ⬇️

artículo científico publicado el 1 de mayo de 2003

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques

scientific article published on 13 May 2019

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

artículo científico publicado en 2013

Demonstration of de novo HIV type 1 production by detection of multiply spliced and unspliced HIV type 1 RNA in paraffin-embedded tonsils

artículo científico

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

artículo científico publicado en 2007

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

artículo científico publicado en 2019

Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2.

artículo científico publicado en 2012

Design of epitope-specific probes for sera analysis and antibody isolation

artículo científico publicado en 2012

Detection of Broadly Neutralizing Activity within the First Months of HIV-1 Infection.

artículo científico publicado en 2016

Detection of diverse HIV-1 genetic subtypes in the USA

scientific article published on 01 November 1995

Determination of HIV-1 Chemokine Coreceptor Tropism Using Transduced Human Osteosarcoma (HOS) Cells

artículo científico publicado el 1 de enero de 1999

Determination of Syncytium-Inducing Phenotype of Primary HIV-1 Isolates Using MT-2 cells

artículo científico publicado el 1 de enero de 1999

Development of a 3Mut-Apex-Stabilized Envelope Trimer that Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

scientific article published on 15 April 2020

Development of a potent Zika virus vaccine using self-amplifying messenger RNA

artículo científico publicado en 2020

Development of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 and performance of an improved AMPLICOR HIV-1 MONITOR test with isolates of diverse subtypes

artículo científico publicado en 1999

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

artículo científico publicado en 2016

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

artículo científico publicado en 2014

Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells

artículo científico publicado en 2005

Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations

scientific article published on 01 July 2019

Disseminated gonococcal infection.

artículo científico publicado en 1992

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

artículo científico publicado en 2020

Diverse HIV-1 subtypes and clinical, laboratory and behavioral factors in a recently infected US military cohort ⬇️

artículo científico publicado el 21 de noviembre de 2003

Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization

artículo científico publicado en 2015

Diversity of the envelope glycoprotein among human immunodeficiency virus type 1 isolates of clade E from Asia and Africa

artículo científico publicado en 1996

Drug resistance patterns, genetic subtypes, clinical features, and risk factors in military personnel with HIV-1 seroconversion

artículo científico publicado en 1999

Dual infection with human immunodeficiency virus type 1 of distinct envelope subtypes in humans

artículo científico publicado en 1995

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

artículo científico publicado en 2020

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

artículo científico publicado en 2021

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

artículo científico publicado en 2021

Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes.

artículo científico publicado en 2005

Early short-term antiretroviral therapy is associated with a reduced prevalence of CD8(+)FoxP3(+) T cells in simian immunodeficiency virus-infected controller rhesus macaques

artículo científico publicado en 2011

Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

artículo científico publicado en 2016

Editorial overview: Vaccines: Vaccines for cancer and infectious diseases

artículo científico publicado en 2015

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

artículo científico publicado en 2016

Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

scientific article published on 01 April 2020

Effect of rAd5-Vector HIV-1 Preventive Vaccines on HIV-1 Acquisition: A Participant-Level Meta-Analysis of Randomized Trials

artículo científico publicado en 2015

Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection

artículo científico publicado en 2016

Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: implications for vaccination

scientific article published on May 2004

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

artículo científico publicado en 2020

Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase

artículo científico publicado en 2021

Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine

artículo científico publicado en 2013

Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs

artículo científico publicado en 2006

Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination

artículo científico publicado en 2002

Eliminating antibody polyreactivity through addition of N-linked glycosylation

artículo científico publicado en 2015

Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology.

artículo científico publicado en 2012

Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain

scientific article published on 04 March 2009

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

artículo científico publicado en 2014

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

artículo científico publicado en 2014

Enhancing the Solubility of HIV-1-neutralizing Antibody 10E8.

artículo científico publicado en 2014

Envelope Variable Region 4 Is the First Target of Neutralizing Antibodies in Early Simian Immunodeficiency Virus mac251 Infection of Rhesus Monkeys ⬇️

artículo científico publicado el 24 de abril de 2012

Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys

artículo científico publicado en 2009

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

artículo científico publicado en 2018

Evaluation of candidate vaccine approaches for MERS-CoV.

artículo científico publicado en 2015

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

artículo científico publicado en 2020

Exclusive and Persistent Use of the Entry Coreceptor CXCR4 by Human Immunodeficiency Virus Type 1 from a Subject Homozygous for CCR5 Δ32 ⬇️

artículo científico publicado el 1 de julio de 1998

Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate

artículo científico publicado en 2005

Exploiting glycan topography for computational design of Env glycoprotein antigenicity

artículo científico publicado en 2018

Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies

artículo científico publicado en 1994

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses

artículo científico publicado en 2020

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

artículo científico publicado en 2020

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

artículo científico publicado en 2011

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies

artículo científico publicado en 2017

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

artículo científico publicado en 2008

Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients

artículo científico publicado en 2021

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

artículo científico publicado en 2018

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

artículo científico publicado en 2016

Gene transfer in humans using a conditionally replicating lentiviral vector

artículo científico publicado en 2006

Gene-Based Vaccination with a Mismatched Envelope Protects against Simian Immunodeficiency Virus Infection in Nonhuman Primates ⬇️

artículo científico publicado el 16 de mayo de 2012

Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation

artículo científico publicado en 2017

Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin

artículo científico publicado en 1995

Genetic, antigenic and serologic characterization of human immunodeficiency virus type 1 from Indonesia

artículo científico publicado en 1997

Genital tract sequestration of SIV following acute infection

artículo científico publicado en 2011

Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

artículo científico publicado en 2013

Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

scientific article published on 31 July 2018

Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses

artículo científico publicado en 2020

Glycan-dependent HIV-specific neutralizing antibodies bind to cells of uninfected individuals

artículo científico publicado en 2019

Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.

artículo científico publicado en 2018

Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity

artículo científico publicado en 2017

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces Gp41 Antibody Immunodominance in Rhesus Macaques

artículo científico publicado en 2017

HIV Immunology Goes Out On a Limb

artículo científico publicado en 2016

HIV Type 1 Env Precursor Cleavage State Affects Recognition by Both Neutralizing and Nonneutralizing gp41 Antibodies ⬇️

artículo científico publicado el 19 de enero de 2011

HIV and peacekeeping operations in Cambodia

artículo científico publicado en 1995

HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate

artículo científico publicado en 2017

HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies

article

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins ⬇️

artículo científico publicado el 8 de agosto de 2012

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

article

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

scientific article published on 01 August 2019

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

artículo científico publicado en 2015

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation

artículo científico publicado en 2016

HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure.

artículo científico publicado en 2018

HIV-1 entry at the mucosal surface: role of antibodies in protection.

artículo científico publicado en 2000

HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile

artículo científico publicado en 2014

HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization

artículo científico publicado en 2005

HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies

artículo científico publicado en 2015

HIV-1 gp120-CD4-Induced Antibody Complex Elicits CD4 Binding Site-Specific Antibody Response in Mice

scientific article published on 17 February 2020

HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes

artículo científico publicado en 2012

HIV-1 neutralizing antibodies display dual specificity for the primary and coreceptor binding sites and preferential recognition of fully-cleaved Env.

artículo científico publicado en 2012

HIV-1 neutralizing antibodies in the genital and respiratory tracts of mice intranasally immunized with oligomeric gp160 ⬇️

artículo científico publicado el 15 de febrero de 1998

HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization

artículo científico publicado en 2014

HIV-1: nature's master of disguise

artículo científico publicado en 2003

HIV. The modern era of HIV-1 vaccine development

artículo científico publicado en 2015

HIV/AIDS: Allied responses

artículo científico publicado en 2007

HIV‐1 neutralizing antibodies: understanding nature's pathways ⬇️

artículo científico publicado el 1 de julio de 2013

Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

artículo científico publicado en 2013

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

artículo científico publicado en 2015

Herpes simplex virus vaccines--why don't antibodies protect?

artículo científico publicado en 1999

Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys

artículo científico publicado en 2004

High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence.

artículo científico publicado en 2016

High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site

artículo científico publicado en 2012

Homologous boosting with adenoviral serotype 5 HIV vaccine (rAd5) vector can boost antibody responses despite preexisting vector-specific immunity in a randomized phase I clinical trial

artículo científico publicado en 2014

Human Immunodeficiency Virus Type 1 Candidate Vaccine Breakthrough Infection ⬇️

artículo científico publicado el 1 de diciembre de 1995

Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs

artículo científico publicado en 2015

Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

artículo científico publicado en 2012

Human dendritic cells as targets of dengue virus infection

artículo científico publicado en 2001

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

artículo científico publicado en 2005

Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein.

artículo científico publicado en 2008

Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells

artículo científico publicado en 2002

Human immunodeficiency virus type 1 neutralizing antibody serotyping using serum pools and an infectivity reduction assay

artículo científico publicado en 1996

Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism ⬇️

artículo científico publicado el 1 de octubre de 1997

Human skin Langerhans cells are targets of dengue virus infection

artículo científico publicado en 2000

Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein.

artículo científico publicado en 1996

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site

Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies

artículo científico publicado en 2014

Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

scientific article published on 01 September 2020

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

artículo científico publicado en 2016

Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models

artículo científico publicado en 2013

Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature

artículo científico publicado en 2020

Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys

artículo científico publicado en 2011

Immune checkpoint modulation enhances HIV-1 antibody induction

artículo científico publicado en 2020

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

artículo científico publicado en 2021

Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group

artículo científico publicado en 1998

Immunization of rhesus macaques with a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine elicits protective antibody response against simian human immunodeficiency virus of R5 phenotype

artículo científico publicado en 2006

Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Ev

artículo científico publicado en 1996

Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus

artículo científico publicado en 2010

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

artículo científico publicado en 2015

Immunogenicity of constrained monoclonal antibody A32-human immunodeficiency virus (HIV) Env gp120 complexes compared to that of recombinant HIV type 1 gp120 envelope glycoproteins

artículo científico publicado en 2004

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

artículo científico publicado en 2014

Immunologic and virologic events in early HIV infection predict subsequent rate of progression

artículo científico publicado en 2010

Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

artículo científico publicado en 2013

Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.

artículo científico publicado en 2004

Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies

artículo científico publicado en 2011

Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies

artículo científico publicado en 2014

Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape

artículo científico publicado en 2018

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques

scientific article published on 20 July 2021

Improvement of antibody functionality by structure-guided paratope engraftment

artículo científico publicado en 2019

Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes

artículo científico publicado en 2014

In vitro reconstitution of B cell receptor-antigen interactions to evaluate potential vaccine candidates.

artículo científico publicado en 2016

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

artículo científico publicado en 2016

Infectious causes of carpal tunnel syndrome: case report and review

artículo científico publicado en 1991

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates

artículo científico publicado en 2009

Influenza Virus H5 DNA Vaccination Is Immunogenic by Intramuscular and Intradermal Routes in Humans ⬇️

artículo científico publicado el 5 de septiembre de 2012

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

artículo científico publicado en 2017

Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer

article

Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Immunogenetic Considerations Underlying B-Cell Biology in the Development of a Pan-Subtype Influenza A Vaccine Targeting the Hemagglutinin Stem

artículo científico publicado en 2017

Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields

scientific article published on 02 October 2019

Isolation of Monoclonal Antibodies from a SHIV-AD8 Infected Rhesus Macaque with Broad Neutralizing Activity.

artículo científico publicado en 2014

Isolation of broadly neutralizing HIV-1 antibodies from high-throughput single B cell culture

artículo científico publicado en 2012

Isolation of human monoclonal antibodies from peripheral blood B cells

artículo científico publicado en 2013

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor

artículo científico publicado en 2016

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

artículo científico publicado en 2020

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

artículo científico publicado en 2019

Lessons from failure--preparing for future HIV-1 vaccine efficacy trials

scientific article published on 27 January 2005

Limited anti-HIV neutralizing antibody breadth and potency before and after HIV superinfection in Danish men who have sex with men

article

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

scientific article published on 12 March 2019

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

scientific article published on 01 February 2020

Longitudinal dynamics of the HIV-specific B cell response during intermittent treatment of primary HIV infection

artículo científico publicado en 2017

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.

scientific article published on 04 May 2009

Lysis of human immunodeficiency virus type 1 by a specific secreted human phospholipase A2

artículo científico publicado en 2006

Macaque dendritic cells infected with SIV-recombinant canarypox ex vivo induce SIV-specific immune responses in vivo

artículo científico publicado en 2004

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

artículo científico publicado en 2017

Mathematical modeling to reveal breakthrough mechanisms in the HIV Antibody Mediated Prevention (AMP) trials

artículo científico publicado en 2020

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

artículo científico publicado en 2016

Maturation Pathways for the Broad and Potent Antibody 10E8 Using a Combination of Next Generation Sequencing, Bioinformatics and Functional Analysis

artículo científico publicado en 2014

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

artículo científico publicado en 2015

Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 ⬇️

artículo científico publicado el 29 de junio de 2011

Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment

artículo científico publicado en 2009

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1.

artículo científico publicado en 2009

Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

artículo científico publicado en 2013

Model Informed Development of VRC01 in Newborn Infants Using a Population Pharmacokinetics Approach

scientific article published on 31 August 2020

Modeling cumulative overall prevention efficacy for the VRC01 phase 2b efficacy trials.

artículo científico publicado en 2018

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

artículo científico publicado en 2016

Monitoring HIV vaccine trial participants for primary infection: studies in the SIV/macaque model

artículo científico publicado en 2009

Monoclonal Antibodies for Prevention and Treatment of COVID-19

artículo científico publicado en 2020

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

artículo científico publicado en 2019

Most rhesus macaques infected with the CCR5-tropic SHIV AD8 generate cross-reactive antibodies that neutralize multiple HIV-1 strains ⬇️

artículo científico publicado el 5 de noviembre de 2012

Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys

artículo científico publicado en 2005

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

artículo científico publicado en 2013

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

artículo científico publicado en 2016

Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial

artículo científico publicado en 2012

Multiple introductions of HIV-1 subtype E into the western hemisphere

artículo científico publicado en 1995

Multiple roles for HIV broadly neutralizing antibodies

scientific article published on 01 October 2019

Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells

artículo científico publicado en 2005

N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function

artículo científico publicado en 2013

Neutralization of HIV-1 Infection of Human Peripheral Blood Mononuclear Cells (PBMC): Antibody Dilution Method

artículo científico publicado el 1 de enero de 1999

Neutralization of HIV-1 Infection of Human Peripheral Blood Mononuclear Cells (PBMC): Infectivity Reduction Method

artículo científico publicado el 1 de enero de 1999

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

artículo científico publicado en 2015

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 17 September 2019

Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs

artículo científico publicado en 2018

Neutralizing and other antiviral antibodies in HIV-1 infection and vaccination

artículo científico publicado en 2007

Neutralizing antibodies against HIV-1: can we elicit them with vaccines and how much do we need?

artículo científico publicado en 2009

Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins

artículo científico publicado en 2005

Neutralizing antibodies from the sera of human immunodeficiency virus type 1-infected individuals bind to monomeric gp120 and oligomeric gp140

artículo científico publicado en 1998

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

artículo científico publicado en 2009

Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

artículo científico publicado en 2014

Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound

artículo científico publicado en 2020

Neutralizing antibody quantification by flow cytometry

artículo científico publicado en 2004

Neutralizing monoclonal antibodies block human immunodeficiency virus type 1 infection of dendritic cells and transmission to T cells.

artículo científico publicado en 1998

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

artículo científico publicado en 2015

Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses

artículo científico publicado en 2021

Next-generation influenza vaccines: opportunities and challenges

artículo científico publicado en 2020

No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys

artículo científico publicado en 2007

Novel Vaccine Technologies: Essential Components of an Adequate Response to Emerging Viral Diseases

artículo científico publicado en 2018

Novel vaccine technologies for the 21st century

artículo científico publicado en 2020

OA05-05. Impact of in vivo CD4 binding during HIV-1 Env trimer immunizations of rhesus macaques.

artículo científico publicado en 2009

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection

artículo científico publicado en 2016

Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1.

artículo científico publicado en 2013

Optimization of a Clade A Env Outer Domain for Enhanced Binding to Germlines of Diverse VRC01 Class Antibodies

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

artículo científico publicado en 2016

Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

artículo científico publicado en 2013

P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys

P09-05. Mechanism of HIV-1 resistance to a monoclonal antibody that effectively targets the site of CD4 attachment

article

P14-10. Comparable immunogenicity of VRC DNA and rAd5 HIV-1 vaccines delivered by intramuscular, subcutaneous and intradermal routes in healthy adults (VRC 011).

artículo científico publicado en 2009

P16-28. The first year: early correlates of long-term HIV progression

article

P19-57 LB. Gene-based vaccination protects against mucosal infection by a heterologous highly pathogenic SIV isolate in rhesus monkeys

article

PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

artículo científico publicado en 2012

Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments

artículo científico publicado en 2017

Partial germline reversions can increase VRC07 potency and breadth.

artículo científico publicado en 2012

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

artículo científico publicado en 2017

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

artículo científico publicado en 2014

Passive transfer studies to elucidate the role of antibody-mediated protection against HIV-1.

artículo científico publicado en 2002

Pathogenicity and Mucosal Transmissibility of the R5-Tropic Simian/Human Immunodeficiency Virus SHIV AD8 in Rhesus Macaques: Implications for Use in Vaccine Studies ⬇️

artículo científico publicado el 30 de mayo de 2012

Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses

artículo científico publicado en 2005

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine

artículo científico publicado en 2006

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

artículo científico publicado en 2006

Phase 1 study of pandemic H1 DNA vaccine in healthy adults

artículo científico publicado en 2015

Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine

scientific article published on 07 March 2007

Phase I clinical evaluation of seasonal influenza hemagglutinin (HA) DNA vaccine prime followed by trivalent influenza inactivated vaccine (IIV3) boost

artículo científico publicado en 2015

Phase I randomized clinical trial of VRC DNA and rAd5 HIV-1 vaccine delivery by intramuscular (i.m.), subcutaneous (s.c.) and intradermal (i.d.) administration (VRC 011)

artículo científico publicado en 2014

Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial

artículo científico publicado en 2013

Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals

artículo científico publicado en 2011

Polyvalent DNA prime and envelope protein boost HIV-1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate

artículo científico publicado en 2005

Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E.

artículo científico publicado en 2006

Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex

artículo científico publicado en 1999

Potent SIV-specific Antibodies Targeting the Cyanovirin Binding Site.

artículo científico publicado en 2014

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

artículo científico publicado en 2017

Potent and synergistic neutralization of human immunodeficiency virus (HIV) type 1 primary isolates by hyperimmune anti-HIV immunoglobulin combined with monoclonal antibodies 2F5 and 2G12 ⬇️

artículo científico publicado el 1 de octubre de 1997

Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.

artículo científico publicado en 2018

Power to detect the effects of HIV vaccination in repeated low-dose challenge experiments

artículo científico publicado en 2009

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

artículo científico publicado en 2020

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

artículo científico

Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

artículo científico publicado en 2002

Preparing for the Next Influenza Pandemic: The Development of a Universal Influenza Vaccine

scientific article published on 01 April 2019

Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeys

artículo científico publicado en 2006

Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys

artículo científico publicado en 2006

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

artículo científico publicado en 2014

Prevalence of genotypic and phenotypic resistance to anti-retroviral drugs in a cohort of therapy-naïve HIV-1 infected US military personnel

artículo científico publicado en 2000

Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation

artículo científico publicado en 2015

Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect ⬇️

artículo científico publicado el 30 de abril de 2013

Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses

artículo científico publicado en 2010

Priming with DNA encoding functional trimers and boosting with soluble trimeric protein elicited tier 2 neutralizing antibodies in non-human primates

artículo científico publicado en 2012

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

artículo científico publicado en 2008

Progress in the rational design of an AIDS vaccine ⬇️

artículo científico publicado el 12 de octubre de 2011

Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail.

artículo científico publicado en 2017

Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies.

artículo científico publicado en 1999

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

artículo científico publicado en 2017

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

artículo científico publicado en 2000

Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys

artículo científico publicado en 2017

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

artículo científico publicado en 2016

Q fever in US military returning from Iraq

artículo científico publicado en 2007

Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection

artículo científico publicado en 2015

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

Rapid development of a DNA vaccine for Zika virus

artículo científico publicado en 2016

Rapid disease progression without seroconversion following primary human immunodeficiency virus type 1 infection--evidence for highly susceptible human hosts

artículo científico publicado en 1997

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

artículo científico publicado en 2015

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes

article

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

artículo científico publicado en 2018

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

artículo científico publicado en 2010

Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1.

artículo científico publicado en 2011

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

artículo científico publicado en 2020

Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

scientific article published on 13 September 2020

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

scientific article published on 19 November 2020

Recombinant vector-induced HIV/SIV-specific CD4+ T lymphocyte responses in rhesus monkeys ⬇️

artículo científico publicado el 27 de julio de 2010

Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines

artículo científico publicado en 2005

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation

artículo científico publicado en 2016

Red man syndrome: incidence, etiology, and prophylaxis.

artículo científico publicado en 1991

Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region

artículo científico publicado en 2009

Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2020

Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates

artículo científico publicado en 2005

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

artículo científico publicado en 2013

Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis

artículo científico publicado en 2015

Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates

artículo científico publicado en 2013

SARS-CoV-2 Viral Variants—Tackling a Moving Target

artículo científico publicado en 2021

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

artículo científico publicado en 2020

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

artículo científico publicado en 2020

SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts

artículo científico publicado en 2016

Safety and Immunogenicity of a rAd35-EnvA Prototype HIV-1 Vaccine in Combination with rAd5-EnvA in Healthy Adults (VRC 012)

artículo científico publicado en 2016

Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

artículo científico publicado en 2019

Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial

artículo científico publicado en 2014

Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial

artículo científico publicado en 2014

Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial

scientific article published on 28 August 2019

Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults.

artículo científico publicado en 2018

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

artículo científico publicado en 2014

Safety, Tolerability, and Pharmacokinetics of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 in HIV-Exposed Newborn Infants

artículo científico publicado en 2019

Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults

artículo científico publicado en 2015

Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial.

artículo científico publicado en 2017

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

artículo científico publicado en 2017

Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study

article by Martin R Gaudinski et al published 2 March 2019 in The Lancet

Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site ⬇️

artículo científico publicado el 14 de marzo de 2012

Selective Increases in HIV-Specific Neutralizing Antibody and Partial Reconstitution of Cellular Immune Responses during Prolonged, Successful Drug Therapy of HIV Infection

article

Selective Modification of Variable Loops Alters Tropism and Enhances Immunogenicity of Human Immunodeficiency Virus Type 1 Envelope.

artículo científico publicado en 2006

Selective modification of variable loops alters tropism and enhances immunogenicity of human immunodeficiency virus type 1 envelope

artículo científico publicado en 2004

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2017

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

artículo científico publicado en 2021

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

scientific article published in Nature Communications

Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry.

artículo científico publicado en 1995

Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.

artículo científico publicado en 2017

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

artículo científico publicado en 2015

Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization

artículo científico publicado en 2014

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

scientific article published on 07 January 2020

Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses

scientific article published on 18 September 2008

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

artículo científico publicado en 2010

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

artículo científico publicado en 2017

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

artículo científico publicado en 2016

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

artículo científico publicado en 2012

Specific Antibody Responses to Vaccination with Bivalent CM235/SF2 gp120: Detection of Homologous and Heterologous Neutralizing Antibody to Subtype E (CRF01.AE) HIV Type 1 ⬇️

artículo científico publicado el 1 de septiembre de 2003

Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.

artículo científico publicado en 2017

Standardized assessment of NAb responses elicited in rhesus monkeys immunized with single- or multi-clade HIV-1 envelope immunogens

artículo científico publicado en 2007

Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

artículo científico publicado en 2015

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

artículo científico publicado en 2010

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

artículo científico publicado en 2014

Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1

artículo científico publicado en 2013

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

artículo científico publicado en 2009

Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation

article

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition

article

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

artículo científico publicado en 2013

Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120.

artículo científico publicado en 2012

Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization

artículo científico publicado en 2012

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

artículo científico publicado en 2017

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

artículo científico publicado en 2014

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

artículo científico publicado en 2004

Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

artículo científico publicado en 2014

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

artículo científico publicado en 2011

Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)

article

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

scientific article published on 01 April 2020

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

artículo científico publicado en 2016

Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain)

article

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-ray and Thermodynamic Characterization ⬇️

artículo científico publicado el 14 de marzo de 2013

Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development

artículo científico publicado en 2020

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

artículo científico publicado en 2017

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

artículo científico publicado en 2020

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

artículo científico publicado en 2020

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes ⬇️

artículo científico publicado en 2020

Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors

artículo científico publicado en 2012

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

artículo científico publicado en 2016

Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry

artículo científico publicado en 2011

Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site

artículo científico publicado en 2009

Structure-guided modification and optimization of antibody VRC07.

artículo científico publicado en 2012

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Successful treatment of Acinetobacter meningitis with meropenem and rifampicin

artículo científico publicado en 2005

Summary report: workshop on the potential risks of antibody-dependent enhancement in human HIV vaccine trials

artículo científico publicado en 1993

Summit proceedings: Biomedical countermeasure development for emerging vector-borne viral diseases

scientific article published on 06 September 2019

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

artículo científico publicado en 2018

Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection

artículo científico publicado en 2015

Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys

artículo científico publicado en 2009

T-cell vaccination reduces simian immunodeficiency virus levels in semen

artículo científico publicado en 2009

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

artículo científico publicado en 2016

The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys

artículo científico publicado en 2011

The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.

artículo científico publicado en 2012

The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region

artículo científico publicado en 2001

The cat and mouse of HIV-1 antibody escape

artículo científico publicado en 2009

The changing face of HIV vaccine research

artículo científico publicado en 2012

The development of CD4 binding site antibodies during HIV-1 infection

artículo científico publicado en 2012

The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes

artículo científico publicado en 2003

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

artículo científico publicado en 2021

The quest for an antibody-based HIV vaccine

artículo científico publicado en 2017

The role of antibodies in HIV vaccines

scientific article published on January 2010

The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

artículo científico publicado en 1997

The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

artículo científico publicado en 2004

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

artículo científico publicado en 2016

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

artículo científico publicado en 2009

Transmission of HIV-1 subtype E in the united states

scientific article published on 01 July 1996

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

artículo científico publicado en 2017

Two antigenically distinct subtypes of human immunodeficiency virus type 1: viral genotype predicts neutralization serotype

artículo científico publicado en 1994

Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design

artículo científico publicado en 2012

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

artículo científico publicado en 2018

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

artículo científico publicado en 2014

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

artículo científico publicado en 2012

Use of Enzyme-digested Virus-like Particles as Probes for Flow Cytometric Sorting of HIV-specific Neutralizing Ab-producing B-cells.

artículo científico publicado en 2014

Use of broadly neutralizing antibodies for HIV-1 prevention

artículo científico publicado en 2017

VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage

artículo científico publicado en 2020

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

artículo científico publicado en 2021

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

artículo científico publicado en 2013

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

artículo científico publicado en 2017

Vaccine reactions

artículo científico publicado en 1998

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

artículo científico publicado en 2015

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

artículo científico publicado en 2016

Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys

artículo científico publicado en 2005

Vaccines for the prevention of HIV-1 disease

artículo científico publicado en 2001

Vaccines: engineering immune evasion

artículo científico publicado en 2006

Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies.

artículo científico publicado en 2014

Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge

artículo científico publicado en 2018

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2015

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

artículo científico publicado en 2015

Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys

artículo científico publicado en 2017

Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

artículo científico publicado en 2020

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

artículo científico publicado en 2017

Virus-specific cellular immune correlates of survival in vaccinated monkeys after simian immunodeficiency virus challenge

artículo científico publicado en 2006

Which New Health Technologies Do We Need to Achieve an End to HIV/AIDS?

artículo científico publicado en 2016

Lista de obras de John R Mascola

1272. Feasibility and Successful Enrollment in Proof-of-Concept Trials to Assess Safety and Efficacy of a Broadly Neutralizing Monoclonal Antibody, VRC01, to Prevent HIV-1 Acquisitionin in Uninfected Individuals

454 pyrosequencing and bioinformatics analysis of the lineage of the broad and potent gp41-directed antibody 10e8.

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial

A Virus-Like Particle Vaccine Elicits Broad Neutralizing Antibody Responses in Humans to All Chikungunya Virus Genotypes

A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults during a Phase 1 Clinical Trial

A West Nile Virus DNA Vaccine Utilizing a Modified Promoter Induces Neutralizing Antibody in Younger and Older Healthy Adults in a Phase I Clinical Trial ⬇️

A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice

A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling

A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates

A human monoclonal antibody specific for the V3 loop of HIV type 1 clade E cross-reacts with other HIV type 1 clades.

A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B.

A method for identification of HIV gp140 binding memory B cells in human blood

A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike

A phase I/II trial of HIV SF2 gp120/MF59 vaccine in seronegative Thais

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike alone

A proof of concept for structure-based vaccine design targeting RSV in humans

A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

A strategic approach to COVID-19 vaccine R&D

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

A1 The role of virus-antibody co-evolution in the development of a V3-glycan-directed HIV-1 broadly neutralizing antibody lineage

AIDS vaccines. Are we ready for human efficacy trials?

Accumulation of follicular CD8+ T cells in pathogenic SIV infection.

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin

Activation and lysis of human CD4 cells latently infected with HIV-1

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

Anti-HIV B Cell lines as candidate vaccine biosensors

Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site

Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline

Antibodies with specificity to native gp120 and neutralization activity against primary human immunodeficiency virus type 1 isolates elicited by immunization with oligomeric gp160.

Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

Antibody responses to envelope glycoproteins in HIV-1 infection

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

Antibody-Dependent Cell-Mediated Cytotoxicity in Simian Immunodeficiency Virus-Infected Rhesus Monkeys ⬇️

Antibody-Dependent Cell-Mediated Viral Inhibition Emerges after Simian Immunodeficiency Virus SIVmac251 Infection of Rhesus Monkeys Coincident with gp140-Binding Antibodies and Is Effective against Neutralization-Resistant Viruses ⬇️

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding ⬇️

Antibody-based HIV-1 vaccines: recent developments and future directions

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

Antigen detection in neutralization assays: high levels of interfering anti-p24 antibodies in some plasma

As antibody findings mount, what comes next? Interview by Kristen Jill Kresge and Regina McEnery

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Author Correction: Next-generation influenza vaccines: opportunities and challenges

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses

Basis and Statistical Design of the Passive HIV-1 Antibody Mediated Prevention (AMP) Test-of-Concept Efficacy Trials

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus

Biochemically Defined HIV-1 Envelope Glycoprotein Variant Immunogens Display Differential Binding and Neutralizing Specificities to the CD4-binding Site ⬇️

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

Brief Report: Prediction of Serum HIV-1 Neutralization Titers After Passive Administration of VRC01

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region