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1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis

artículo científico publicado en 2004

9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

artículo científico publicado en 2021

A Cryptic BCR-PDGFRB Fusion Resulting in a Chronic Myeloid Neoplasm With Monocytosis and Eosinophilia: A Novel Finding With Treatment Implications

artículo científico publicado en 2020

A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.

artículo científico publicado en 2018

A census of human cancer genes

artículo científico publicado en 2004

A comprehensive catalogue of somatic mutations from a human cancer genome

artículo científico publicado en 2010

A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus

scientific article published on 01 March 1993

A functional genomic approach to actionable gene fusions for precision oncology

artículo científico publicado en 2022

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy

artículo científico publicado en 2006

A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers

artículo científico publicado en 2006

A novel Gln358Glu mutation in ectodysplasin A associated with X-linked dominant incisor hypodontia

artículo científico publicado en 2007

A pathogenic mosaic TP53 mutation in two germ layers detected by next generation sequencing

artículo científico publicado en 2014

A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis

scientific article published on 01 August 2019

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

artículo científico publicado en 2005

A small-cell lung cancer genome with complex signatures of tobacco exposure

artículo científico publicado en 2010

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

scientific journal article

A survey of RNA editing in human brain

artículo científico publicado en 2004

A survey of homozygous deletions in human cancer genomes

artículo científico publicado en 2005

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

artículo científico publicado en 2009

AACR Cancer Progress Report 2012.

artículo científico publicado en 2012

Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers

scientific article published on 01 September 1998

Activating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors

artículo científico publicado en 2016

Acute promyelocytic leukemia (APL) with an IRF2BP2-RARA fusion transcript: an aggressive APL variant

scientific article published on 11 July 2020

Allele loss on chromosome 1p36 in epithelial ovarian cancers

artículo científico publicado en 2001

Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma

artículo científico publicado en 2009

An Alu polymorphism intragenic to the TP53 gene ⬇️

artículo científico publicado el 25 de diciembre de 1991

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

artículo científico publicado en 2016

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

artículo científico publicado en 2015

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

artículo científico publicado en 2022

Antitumor Response of VEGFR2- and VEGFR3-Amplified Angiosarcoma to Pazopanib.

artículo científico publicado en 2016

Applying Artificial Intelligence to Address the Knowledge Gaps in Cancer Care

artículo científico publicado en 2018

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

artículo científico publicado en 2007

Are sarcomas hereditary?

artículo científico publicado en 2016

Assessing tumor heterogeneity using ctDNA to predict and monitor therapeutic response in metastatic breast cancer

artículo científico publicado en 2019

Associations of inflammation with symptom burden in patients with acute myeloid leukemia

artículo científico publicado en 2018

Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

artículo científico publicado en 2019

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

artículo científico publicado en 2019

Author Correction: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

artículo científico publicado en 2018

AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes.

artículo científico publicado en 2007

BRAF and RAS mutations in human lung cancer and melanoma

artículo científico publicado en 2002

BRCA 1 and 2--A Genetic Link to Familial Breast and Ovarian Cancer

artículo científico publicado en 1997

BRCA1 and BRCA2 in breast cancer families from Wales: moderate mutation frequency and two recurrent mutations in BRCA1

artículo científico publicado en 1998

BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.

artículo científico publicado en 1996

BRCA1 expression is not directly responsive to estrogen

artículo científico publicado en 1997

BRCA1 mutations in primary breast and ovarian carcinomas

artículo científico publicado en 1994

BRCA2 mutations in primary breast and ovarian cancers

artículo científico publicado en 1996

Backseat drivers take the wheel

artículo científico publicado en 2007

Bcl10 is not a target for frequent mutation in human carcinomas

artículo científico publicado en 1999

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

artículo científico publicado en 2016

Breast cancer genome heterogeneity: a challenge to personalised medicine?

artículo científico publicado en 2011

C-kit gene mutations in adenoid cystic carcinoma are rare.

artículo científico publicado en 2010

CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes

artículo científico publicado en 2009

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

artículo científico publicado en 2010

COSMIC 2005

artículo científico publicado en 2006

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

artículo científico publicado en 2011

COSMIC: the catalogue of somatic mutations in cancer.

artículo científico publicado en 2011

Cancer Genomics in Clinical Context

artículo científico publicado en 2015

Cancer and genomics

artículo científico publicado en 2001

Cancer genomics: from discovery science to personalized medicine

artículo científico publicado en 2011

Cancer: understanding the target

artículo científico publicado en 2004

Cell cycle control of BRCA2

artículo científico publicado en 1996

Characterization of the rat and mouse homologues of the BRCA2 breast cancer susceptibility gene ⬇️

artículo científico publicado el 1 de agosto de 1997

Chromosomal instability confers intrinsic multidrug resistance.

artículo científico publicado en 2011

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

scientific article published on 21 May 2007

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

scientific article published in Nature Communications

Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia

artículo científico publicado en 2018

Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents

artículo científico publicado en 2016

Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

artículo científico publicado en 2018

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

artículo científico publicado en 2011

Clonal evolution of acute myeloid leukemia relapsed after 19 years of remission

artículo científico publicado en 2015

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

artículo científico publicado en 2020

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

artículo científico publicado en 2015

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

artículo científico publicado en 2015

Comparative genomics of high grade neuroendocrine carcinoma of the cervix

artículo científico publicado en 2020

Complex landscapes of somatic rearrangement in human breast cancer genomes

artículo científico publicado en 2009

Comprehensive T cell repertoire characterization of non-small cell lung cancer

artículo científico publicado en 2020

Confirmation of a gene locus for medullary cystic kidney disease (MCKD2) on chromosome 16p12

artículo científico publicado en 2001

Copy number alterations detected as clonal hematopoiesis of indeterminate potential

scientific article published on 19 June 2017

Correction: Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

artículo científico publicado en 2020

Corrigendum to: CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes

artículo científico publicado en 2010

Corrigendum: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

artículo científico publicado en 2012

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference

article

Cross-site concordance evaluation of tumor DNA and RNA sequencing platforms for the CIMAC-CIDC network

artículo científico publicado en 2020

DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome

artículo científico publicado en 2011

DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

artículo científico publicado en 2017

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

artículo científico publicado en 2011

Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes

artículo científico publicado en 2021

Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

scientific article published on 11 May 2020

Detection of BRCA1 mutations in women with early-onset ovarian cancer by use of the protein truncation test.

artículo científico publicado en 1996

Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms

artículo científico publicado en 1992

Dideoxy fingerprinting assay forBRCA1 mutation analysis ⬇️

artículo científico publicado el 1 de julio de 1997

Differential and limited expression of mutant alleles in multiple myeloma

artículo científico publicado en 2014

Dinucleotide repeat polymorphism in the THRA1 gene

artículo científico publicado el 1 de abril de 1992

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

artículo científico publicado en 2020

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

artículo científico publicado en 2013

Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

artículo científico publicado en 2019

Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy

scientific article published on 12 April 2022

Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion

artículo científico publicado en 2015

Ductal carcinoma in situ: to treat or not to treat, that is the question

scientific article published on 09 July 2019

Effect of Smoking on Breast Cancer in Carriers of Mutant BRCA1 or BRCA2 Genes

article

Effect of antibiotics on gut and vaginal microbiomes associated with cervical cancer development in mice

scientific article published on 11 September 2020

Efficacy and predictors of response of lenalidomide and rituximab in patients with treatment-naive and relapsed CLL

scientific article published on 01 May 2019

Ehlers-Danlos syndrome with severe early-onset periodontal disease (EDS-VIII) is a distinct, heterogeneous disorder with one predisposition gene at chromosome 12p13.

artículo científico publicado en 2003

Emerging patterns of somatic mutations in cancer

artículo científico publicado en 2013

Erratum: Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

scholarly article by Colin S Cooper et al published June 2015 in Nature Genetics

Erratum: Corrigendum: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

scholarly article published in Nature Genetics

Erratum: Corrigendum: Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

scholarly article published in Nature Genetics

Erratum: Corrigendum: Signatures of mutational processes in human cancer

artículo científico publicado en 2013

Erratum: Identification of the breast cancer susceptibility gene BRCA2

artículo científico publicado en 1996

Estimation of rearrangement phylogeny for cancer genomes

artículo científico publicado en 2011

Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC).

artículo científico publicado en 2016

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

artículo científico publicado en 2002

Evidence for two senescence loci on human chromosome 1.

artículo científico publicado en 1996

Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

artículo científico publicado en 2021

Evolution of genomic and T cell repertoire heterogeneity of malignant pleural mesothelioma under dasatinib treatment

scientific article published on 14 August 2020

Exclusion of biglycan mutations in a cohort of patients with neuromuscular disorders

artículo científico publicado en 2008

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

artículo científico publicado en 2011

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

scientific article published on 01 May 2012

Exome sequencing of liver fluke-associated cholangiocarcinoma

artículo científico publicado en 2012

Failure of senescent cells to phosphorylate the RB protein

artículo científico publicado el 1 de julio de 1991

Familial breast-ovarian cancer syndromes: BRCA1 and BRCA2.

artículo científico publicado en 1998

Features of non-activation dendritic state and immune deficiency in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

scientific article published on 06 December 2019

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

artículo científico publicado en 2008

Fine-scale survey of X chromosome copy number variants and indels underlying intellectual disability

artículo científico publicado en 2010

Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families

artículo científico publicado en 1998

Frequency of germline and somatic BRCA1 mutations in ovarian cancer

scientific article published on 01 October 1998

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

artículo científico publicado en 2007

Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma

artículo científico publicado en 2013

FusionPathway: Prediction of pathways and therapeutic targets associated with gene fusions in cancer.

artículo científico publicado en 2018

Future cancer research priorities in the USA: a Lancet Oncology Commission

artículo científico publicado en 2017

GLO1-A novel amplified gene in human cancer

artículo científico publicado en 2010

Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

artículo científico publicado en 2014

Genetic and molecular basis for cellular senescence.

artículo científico publicado en 1993

Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing

artículo científico publicado en 2010

Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

scientific article published on 01 October 2019

Genetic screens using the piggyBac transposon

artículo científico publicado en 2011

Genetic susceptibility testing and prophylactic oophorectomy

artículo científico publicado en 1999

Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer

artículo científico publicado en 2012

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool

artículo científico publicado en 2013

Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma

artículo científico publicado en 2017

Genomic Profiling of Multifocal Intrahepatic Cholangiocarcinoma Reveals Intraindividual Concordance of Genetic Alterations

artículo científico publicado en 2020

Genomic Rearrangement Signatures and Clinical Outcomes in High-Grade Serous Ovarian Cancer.

artículo científico publicado en 2018

Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer

scholarly article

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer

artículo científico publicado en 2022

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

artículo científico publicado en 2017

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

artículo científico publicado en 2014

Genomic assessment distinguishes intrapulmonary metastases from synchronous primary lung cancers

artículo científico publicado en 2020

Genomic heterogeneity of multiple synchronous lung cancer

artículo científico publicado en 2016

Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung

Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin.

artículo científico publicado en 2018

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

artículo científico publicado en 2012

Germline DNA Sequencing Reveals Novel Mutations Predictive of Overall Survival in a Cohort of Patients with Pancreatic Cancer

artículo científico publicado en 2019

Germline DNMT3A mutation in familial acute myeloid leukaemia

artículo científico publicado en 2020

Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery

artículo científico publicado en 2021

Growth and transformation suppressor genes for BHK Syrian hamster cells on human chromosomes 1 and 11.

artículo científico publicado en 1992

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

artículo científico publicado en 2017

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

artículo científico publicado en 2014

High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer

artículo científico publicado en 2000

High prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer

artículo científico publicado en 2018

High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison.

artículo científico publicado en 2006

High-resolution analysis of DNA copy number using oligonucleotide microarrays

artículo científico publicado en 2004

High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics

article by Maurizio Pellegrino et al published September 2018 in Genome Research

Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer

artículo científico publicado en 2015

Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer

artículo científico publicado en 2016

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

artículo científico publicado en 2011

Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype-phenotype correlation

artículo científico publicado en 2009

Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype-phenotype correlation.

artículo científico publicado en 2012

Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers

artículo científico publicado en 1995

Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia

artículo científico

Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer

artículo científico publicado en 2014

Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma

scientific article published on 07 November 2019

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

artículo científico publicado en 2008

Identification of two distinct deleted regions on chromosome 13 in prostate cancer

artículo científico publicado en 1998

Immune and Circulating Tumor DNA Profiling After Radiation Treatment for Oligometastatic Non-Small Cell Lung Cancer: Translational Correlatives from a Mature Randomized Phase II Trial

artículo científico publicado en 2019

Immuno-genomic landscape of osteosarcoma

scientific article published on 21 February 2020

Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.

artículo científico publicado en 2018

Improving the detection of patients with inherited predispositions to hematologic malignancies using next-generation sequencing-based leukemia prognostication panels

scientific article published on 06 April 2018

In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

artículo científico publicado en 2008

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

artículo científico publicado en 2017

Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes

artículo científico publicado en 2018

Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma

artículo científico publicado en 2010

International network of cancer genome projects

artículo científico publicado en 2010

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

artículo científico publicado en 2012

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

artículo científico publicado en 2014

Intratumor heterogeneity: seeing the wood for the trees.

artículo científico publicado en 2012

Investigation of the role of G1/S cell cycle mediators in cellular senescence

artículo científico publicado en 1993

Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture

artículo científico publicado en 1994

JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis

artículo científico publicado en 2007

K-ras mutations in Müllerian inclusion cysts associated with serous borderline tumors of the ovary

artículo científico publicado en 2001

KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary.

artículo científico publicado en 2018

LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition

artículo científico publicado en 2009

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

artículo científico publicado en 2016

Late relapse in acute myeloid leukemia (AML): clonal evolution or therapy-related leukemia?

scholarly article by Musa Yilmaz et al published 16 January 2019 in Blood Cancer Journal

Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia

artículo científico publicado en 2021

Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma

artículo científico publicado en 2022

Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region

artículo científico publicado en 1993

Linking Associations of Rare Low-Abundance Species to Their Environments by Association Networks.

artículo científico publicado en 2018

Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer

artículo científico publicado en 2018

Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1.

artículo científico publicado en 1994

Localization of the gene for distal hereditary motor neuronopathy VII (dHMN-VII) to chromosome 2q14.

artículo científico publicado en 2001

Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

artículo científico publicado en 2021

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

artículo científico publicado en 2016

Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment

artículo científico publicado en 2007

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

artículo científico publicado en 2002

Lung cancer: intragenic ERBB2 kinase mutations in tumours

artículo científico publicado en 2004

MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma

artículo científico publicado en 2019

MYC protein expression is an important prognostic factor in acute myeloid leukemia

artículo científico publicado en 2018

Managing Clonal Hematopoiesis in Patients With Solid Tumors

artículo científico publicado en 2018

Managing hereditary ovarian cancer risk

artículo científico publicado en 1999

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

artículo científico publicado en 2011

Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma

scientific article published on 01 May 2019

Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer

scientific article published on 01 November 1996

Mining cancer genomes in COSMIC.

artículo científico publicado en 2012

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

artículo científico publicado en 2014

Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer

scientific article published on 01 April 2020

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

artículo científico publicado en 2019

Molecular and immune heterogeneity in synchronous melanoma metastases.

artículo científico publicado en 2015

MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data

artículo científico publicado en 2016

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

scientific article published on 05 July 2019

Multi-site desmoplastic small round cell tumors are genetically related and immune-cold

artículo científico publicado en 2022

Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy

scientific article published on 07 January 2020

Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma

artículo científico publicado en 2020

Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

artículo científico publicado en 2020

Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response

artículo científico publicado en 2019

Multiregion gene expression profiling reveals heterogeneity in molecular subtypes and immunotherapy response signatures in lung cancer

artículo científico publicado en 2018

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

artículo científico publicado en 2006

Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families

artículo científico publicado en 1996

Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line

artículo científico publicado en 1994

Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias

artículo científico publicado en 1998

Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers

artículo científico publicado en 1998

Mutational processes molding the genomes of 21 breast cancers

artículo científico publicado en 2012

Mutational signatures of ionizing radiation in second malignancies

artículo científico publicado en 2016

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor

artículo científico publicado en 2007

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

artículo científico publicado en 2006

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

artículo científico publicado en 2007

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus

artículo científico publicado en 2007

Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly

artículo científico publicado en 2007

Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation

artículo científico publicado en 2004

Mutations in the RSK2(RPS6KA3) gene cause Coffin-Lowry syndrome and nonsyndromic X-linked mental retardation

artículo científico publicado en 2006

Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

artículo científico publicado en 2018

Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis

artículo científico publicado en 2003

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation

artículo científico publicado en 2006

Mutations in the guanine nucleotide exchange factor gene IQSEC2 cause nonsyndromic intellectual disability

artículo científico publicado en 2010

Mutations of the BRAF gene in human cancer

artículo científico publicado en 2002

Neoadjuvant Chemotherapy Increases Cytotoxic T cell, Tissue Resident Memory T cell and B Cell Infiltration in Resectable Non-Small Cell Lung Cancer

artículo científico publicado en 2020

Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma

artículo científico publicado en 2020

Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial

artículo científico publicado en 2021

Neoantigen responses, immune correlates, and favorable outcomes after ipilimumab treatment of patients with prostate cancer

scientific article published on 01 April 2020

Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations

artículo científico publicado en 2015

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

artículo científico publicado en 2016

Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome

artículo científico publicado en 2011

Novel consensus DNA‐binding sequence for BRCA1 protein complexes ⬇️

artículo científico publicado el 1 de octubre de 2003

Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation

artículo científico publicado en 2008

Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2.

artículo científico publicado en 2011

Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.

artículo científico publicado en 2017

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

artículo científico publicado en 2014

Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes

artículo científico publicado en 2017

PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy

artículo científico publicado en 2018

PRDM16s transforms megakaryocyte-erythroid progenitors into myeloid leukemia-initiating cells

scientific article published on 03 July 2019

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative

artículo científico publicado en 2020

Patient-reported fatigue prior to treatment is prognostic of survival in patients with acute myeloid leukemia

artículo científico publicado en 2018

Patterns of somatic mutation in human cancer genomes

artículo científico publicado en 2007

Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies

artículo científico publicado en 2011

Phase I trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors

artículo científico publicado en 2010

Polygenic in vivo validation of cancer mutations using transposons

artículo científico publicado en 2014

Pre-counseling education materials for BRCA testing: does tailoring make a difference?

artículo científico publicado en 2002

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

scientific article published on 01 February 2019

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

artículo científico publicado en 2010

Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study

artículo científico

Prevalence of BRCA1 and BRCA2 mutations in male breast cancer patients in Canada

artículo científico publicado en 2000

Prevalence of recurrent oncogenic fusion in mismatch repair-deficient colorectal carcinoma with hypermethylated MLH1 and wild-type BRAF and KRAS

scientific article published on 05 February 2019

Processed pseudogenes acquired somatically during cancer development

artículo científico publicado en 2014

Programmed Death Ligand 1 Heterogeneity and its Impact on Benefit from Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer

scientific article published on 07 May 2020

Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets

artículo científico publicado en 2020

Publisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

artículo científico publicado en 2020

RNA editing of human microRNAs

artículo científico publicado en 2006

RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1

scientific article published on 25 April 2019

Recurrent KRAS codon 146 mutations in human colorectal cancer

artículo científico publicado en 2006

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

artículo científico publicado en 2014

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

artículo científico publicado en 2017

Refined mapping of X-linked reticulate pigmentary disorder and sequencing of candidate genes

artículo científico publicado en 2008

Role of BRCA1 mutation screening in the management of familial ovarian cancer

artículo científico publicado en 1996

SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome

artículo científico publicado en 2008

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

artículo científico publicado en 2013

Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults

artículo científico publicado en 2006

Sequencing analysis of BRAF mutations in human cancers

artículo científico publicado en 2006

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

artículo científico publicado en 2018

Signatures of mutation and selection in the cancer genome

artículo científico publicado en 2010

Signatures of mutational processes in human cancer

artículo científico publicado en 2013

Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.

artículo científico publicado en 2002

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

artículo científico publicado en 2021

Single-cell paired-end genome sequencing reveals structural variation per cell cycle

artículo científico publicado en 2013

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

artículo científico publicado en 2011

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

artículo científico publicado en 2020

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

artículo científico publicado en 2009

Somatic mutations of the protein kinase gene family in human lung cancer

artículo científico publicado en 2005

Somatic structural rearrangements in genetically engineered mouse mammary tumors

artículo científico publicado en 2010

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma

artículo científico publicado en 2020

Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma.

artículo científico publicado en 2017

State of the science: an update on renal cell carcinoma

artículo científico publicado en 2012

Statistical analysis of pathogenicity of somatic mutations in cancer

artículo científico publicado en 2006

Statistical tests for intra-tumour clonal co-occurrence and exclusivity

artículo científico publicado en 2021

Stella-Cre mice are highly efficient Cre deleters

artículo científico publicado en 2011

Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation

artículo científico publicado en 2008

Systematic identification of genomic markers of drug sensitivity in cancer cells

artículo científico publicado en 2012

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

artículo científico publicado en 2010

T CELL REPERTOIRE IN COMBINATION WITH T CELL DENSITY PREDICTS CLINICAL OUTCOMES IN PATIENTS WITH MERKEL CELL CARCINOMA

artículo científico publicado en 2020

T(6;14)(q25;q32) involves BCL11B and is highly associated with mixed-phenotype acute leukemia, T/myeloid

artículo científico publicado en 2020

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.

artículo científico publicado en 2017

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

artículo científico publicado en 2012

Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations.

artículo científico publicado en 2018

Testing for hereditary breast and ovarian cancer in the southeastern United States

artículo científico publicado en 2000

The BRAF gene is frequently mutated in malignant melanoma

artículo científico publicado en 2004

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

artículo científico publicado en 2004

The Catalogue of Somatic Mutations in Cancer (COSMIC)

artículo científico publicado en 2008

The Life History of 21 Breast Cancers

The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma

scientific article published on 06 November 2019

The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies

artículo científico publicado en 2015

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma

artículo científico publicado en 2018

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders

artículo científico publicado en 2005

The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma

artículo científico publicado en 2022

The cancer genome

artículo científico publicado en 2009

The circular RNome of primary breast cancer

scientific article published on 28 January 2019

The continuing search for cancer-causing somatic mutations

artículo científico publicado en 2007

The driver landscape of sporadic chordoma

artículo científico publicado en 2017

The gene for juvenile hyaline fibromatosis maps to chromosome 4q21

artículo científico publicado en 2002

The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics

artículo científico publicado en 2021

The human mammary-derived growth inhibitor (MDGI) gene: genomic structure and mutation analysis in human breast tumors

artículo científico publicado en 1996

The landscape of cancer genes and mutational processes in breast cancer

artículo científico publicado en 2012

The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype

scientific article published on 25 July 2019

The life history of 21 breast cancers

artículo científico publicado en 2012

The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene

artículo científico publicado en 2007

The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2

artículo científico publicado en 2000

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

artículo científico publicado en 2010

The somatic mutation landscape of premalignant colorectal adenoma.

artículo científico publicado en 2017

The topography of mutational processes in breast cancer genomes

artículo científico publicado en 2016

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

artículo científico publicado en 2018

Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis

artículo científico publicado en 2018

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

artículo científico publicado en 2010

Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility

artículo científico publicado en 2003

Whole exome sequencing of adenoid cystic carcinoma

scientific article published on 17 June 2013

Whole genome DNA copy number changes identified by high density oligonucleotide arrays

artículo científico publicado en 2004

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

artículo científico publicado en 2011

X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment

artículo científico publicado en 2008

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