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Lista de obras de Iain J Clarke

Active immunization of ewes against luteinizing hormone releasing hormone, and its effects on ovulation and gonadotrophin, prolactin and ovarian steroid secretion

artículo científico publicado el 1 de julio de 1978

Activin A: from sometime reproductive factor to genuine cytokine.

artículo científico publicado en 2005

Alteration in the relationship between tanycytes and gonadotropin releasing hormone (GnRH) neurosecretory terminals following long-term metabolic manipulation in the sheep.

artículo científico

An outbreak of gonadal hypoplasia in a sheep flock: clinical, pathological and endocrinological features, and aetiological studies

artículo científico publicado el 28 de noviembre de 1992

Angiotensin II- and phorbol ester-induced steroidogenesis by ovine adrenocortical cells: effect of sex and the gonadal status of the donor animal.

artículo científico publicado en 1998

Angiotensin peptides in brain and pituitary of rat and sheep.

artículo científico publicado en 1992

Antidepressants, sex steroids and pituitary-adrenal response in sheep.

artículo científico publicado en 2004

Blockade of the oestrogen-induced luteinizing hormone surge in ovariectomized ewes by a highly selective opioid mu-receptor agonist: evidence for site of action.

artículo científico publicado en 1998

CNS leptin action modulates immune response and survival in sepsis.

artículo científico publicado en 2010

Central administration of corticotrophin releasing hormone but not arginine vasopressin stimulates the secretion of luteinizing hormone in rams in the presence and absence of testosterone

artículo científico publicado en 1999

Central infusion of leptin does not increase AMPK signaling in skeletal muscle of sheep.

artículo científico publicado en 2010

Central leptin activates mitochondrial function and increases heat production in skeletal muscle.

artículo científico publicado en 2011

Characterization of the projections to the hypothalamic paraventricular and periventricular nuclei in the female sheep brain, using retrograde tracing and immunohistochemistry.

artículo científico publicado en 2009

Citalopram (antidepressant) administration causes sexual dysfunction in male mice through RF-amide related peptide in the dorsomedial hypothalamus

artículo científico publicado en 2010

Components of the Neuronal Exocytotic Machinery in the Anterior Pituitary of the Ovariectomised Ewe and the Effects of Oestrogen in Gonadotropes as Studied with Confocal Microscopy

artículo científico publicado el 1 de abril de 1998

Continuous Kisspeptin restores Luteinizing Hormone pulsatility following cessation by a Neurokinin B antagonist in female sheep.

artículo científico publicado en 2017

Control of GnRH secretion: one step back.

artículo científico publicado en 2011

Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity.

artículo científico publicado en 2011

Differences in mitochondrial DNA inheritance and function align with body conformation in genetically lean and fat sheep

artículo científico publicado en 2015

Differential responses in anterior pituitary luteinizing hormone (LH) content and LHβ- and α-subunit MRNA, and plasma concentrations of LH and testosterone, in bulls treated with the LH-releasing hormone agonist deslorelin

artículo científico publicado el 1 de noviembre de 1997

Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

artículo científico publicado en 2009

Disparate effects of feeding on core body and adipose tissue temperatures in animals selectively bred for Nervous or Calm temperament.

artículo científico publicado en 2010

Distribution and characterization of peptidylglycine alpha-amidating monooxygenase activity in the ovine brain and hypothalamo-pituitary axis

artículo científico publicado el 1 de febrero de 1992

Distribution, Isolation and Sequence Analysis of the C-Terminal Heptapeptide of Pro-Enkephalin A (YGGFMRF) from the Ovine Median Eminence

artículo científico publicado en 1991

Does the type II glucocorticoid receptor mediate cortisol-induced suppression in pituitary responsiveness to gonadotropin-releasing hormone?

artículo científico publicado en 2004

Effect of RF-amide-related peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes.

artículo científico publicado en 2009

Effect of gonadotropin-inhibitory hormone on luteinizing hormone secretion in humans.

artículo científico publicado en 2017

Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe.

artículo científico publicado en 2017

Effects of bovine follicular fluid on pulsatile secretion of gonadotrophin-releasing hormone and gonadotrophins in ovariectomized ewes

artículo científico publicado en 1989

Effects of central infusion of ghrelin on food intake and plasma levels of growth hormone, luteinizing hormone, prolactin, and cortisol secretion in sheep.

artículo científico publicado en 2005

Effects of changing gonadotropin-releasing hormone pulse frequency and estrogen treatment on levels of estradiol receptor-alpha and induction of Fos and phosphorylated cyclic adenosine monophosphate response element binding protein in pituitary gona

artículo científico publicado en 2004

Effects of estrogen and estrous cycle on glucocorticoid and catecholamine responses to stress in sheep

artículo científico publicado en 1998

Effects of vasopressin and elimination of corticotropin-releasing hormone-target cells on pro-opiomelanocortin mRNA levels and adrenocorticotropin secretion in ovine anterior pituitary cells

artículo científico publicado el 1 de julio de 1997

Effects on plasma luteinizing hormone levels of microinjection of noradrenaline and adrenaline into the septo-preoptic area of the brain of the ovariectomized ewe: changes with season and chronic oestrogen treatment.

artículo científico publicado en 1992

Elevated KiSS-1 expression in the arcuate nucleus prior to the cyclic preovulatory gonadotrophin-releasing hormone/lutenising hormone surge in the ewe suggests a stimulatory role for kisspeptin in oestrogen-positive feedback.

artículo científico publicado en 2006

Estradiol-17beta-responsive A1 and A2 noradrenergic cells of the brain stem project to the bed nucleus of the stria terminalis in the ewe brain: a possible route for regulation of gonadotropin releasing hormone cells.

artículo científico publicado en 2009

Estrogen transiently increases delayed rectifier, voltage-dependent potassium currents in ovine gonadotropes.

artículo científico publicado en 1999

Evidence that Dopaminergic Neurons are not Involved in the Negative Feedback Effect of Testosterone on Luteinizing Hormone in Rams in the Non-Breeding Season

artículo científico publicado en 1992

Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep

artículo científico publicado en 2015

Evidence that RF-amide related peptide-3 is not a mediator of the inhibitory effects of psychosocial stress on gonadotrophin secretion in ovariectomised ewes

artículo científico publicado en 2011

Ewes With Divergent Cortisol Responses to ACTH Exhibit Functional Differences in the Hypothalamo-Pituitary-Adrenal (HPA) Axis

artículo científico publicado en 2016

Exercise counteracts the homeostatic decrease in thermogenesis caused by caloric restriction in sheep.

artículo científico publicado en 2018

Expression of genes for Kisspeptin (KISS1), Neurokinin B (TAC3), Prodynorphin (PDYN), and gonadotropin inhibitory hormone (RFRP) across natural puberty in ewes

scientific article published on 01 March 2020

Expression of genes for appetite-regulating peptides in the hypothalamus of genetically selected lean and fat sheep.

artículo científico publicado en 2009

Expression of regulatory neuropeptides in the hypothalamus of red deer (Cervus elaphus) reveals anomalous relationships in the seasonal control of appetite and reproduction

artículo científico publicado en 2016

Glucocorticoid treatment facilitates development of a metabolic syndrome in ovariectomized Macaca Mulatta fed a high fat diet.

artículo científico publicado en 2017

Gonadotropin inhibitory hormone (GnIH) as a regulator of gonadotropes.

artículo científico

Gonadotropin inhibitory hormone function in mammals.

scientific article published on 07 January 2010

Gonadotropin-inhibitory hormone (GnIH) secretion into the ovine hypophyseal portal system.

artículo científico publicado en 2012

Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding

artículo científico publicado en 2012

Gonadotropin-inhibitory hormone promoter-driven enhanced green fluorescent protein expression decreases during aging in female rats

artículo científico publicado en 2014

Growth axis maturation is linked to nutrition, growth and developmental rate

artículo científico publicado en 2015

High cortisol response to adrenocorticotrophic hormone identifies ewes with reduced melanocortin signalling and increased propensity to obesity.

artículo científico publicado en 2015

High cortisol responses identify propensity for obesity that is linked to thermogenesis in skeletal muscle.

artículo científico publicado en 2013

High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage

artículo científico publicado en 2014

Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate.

artículo científico publicado en 2010

Hypothalamus as an endocrine organ.

artículo científico publicado en 2015

IGFBP-2 inhibits adipogenesis and lipogenesis in human visceral, but not subcutaneous, adipocytes.

artículo científico publicado en 2014

Improved detection of mycobacteria species in formalin-fixed tissue sections

artículo científico publicado en 2011

Induction of plasma LH surges and normal luteal function in acyclic post-partum ewes by the pulsatile administration of LH-RH

artículo científico publicado el 1 de mayo de 1984

Influence of photoperiod and gonadal status on food intake, adiposity, and gene expression of hypothalamic appetite regulators in a seasonal mammal.

artículo científico publicado en 2006

Inhibition of compensatory renal growth by the N-terminus of a sheep-derived peptide

artículo científico publicado en 2008

Inhibition of ovulation and absence of positive feedback in ewes immunized against luteinizing hormone releasing hormone [proceedings]

artículo científico publicado el 1 de diciembre de 1977

Interface between metabolic balance and reproduction in ruminants: focus on the hypothalamus and pituitary

artículo científico

Is centrally induced alveolar bone loss in a large animal model preventable by peripheral hormone substitution?

artículo científico publicado en 2017

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season.

artículo científico publicado en 2006

Kisspeptin Cells in the Ovine Arcuate Nucleus Express Prolactin Receptor but not Melatonin Receptor

artículo científico publicado el 1 de octubre de 2011

Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence

article

Kisspeptin Stimulates Growth Hormone Release by Utilizing Neuropeptide Y Pathways and Is Dependent on the Presence of Ghrelin in the Ewe.

artículo científico publicado en 2017

Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells

artículo científico publicado en 2010

Kisspeptin is a component of the pulse generator for GnRH secretion in female sheep but not the pulse generator

artículo científico publicado en 2015

Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge.

artículo científico publicado en 2009

Kisspeptin signaling is required for the luteinizing hormone response in anestrous ewes following the introduction of males

artículo científico publicado en 2013

LH release and luteal function in post-partum acyclic ewes after the pulsatile administration of LH-RH

artículo científico publicado el 1 de marzo de 1983

Leptin enhances insulin sensitivity by direct and sympathetic nervous system regulation of muscle IGFBP-2 expression: evidence from nonrodent models.

artículo científico publicado en 2014

Leptin inhibits bone formation not only in rodents, but also in sheep

scientific article published on 01 October 2006

Levels of dopamine beta hydroxylase immunoreactivity in the preoptic hypothalamus of the ovariectomised ewe following injection of oestrogen: evidence for increased noradrenaline release around the time of the oestrogen-induced surge in luteinizing

artículo científico publicado en 1999

Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection.

artículo científico publicado en 2012

Many Peptides that Are Present in the External Zone of the Median Eminence Are Not Secreted into the Hypophysial Portal Blood of Sheep

artículo científico publicado el 1 de mayo de 1993

Melatonin Receptors in the Brain and Pituitary Gland of Hypothalamo‐Pituitary Disconnected Soay Rams

artículo científico publicado el 1 de agosto de 1997

Mesenteric infusion of a volatile fatty acid prevents body weight loss and transiently restores luteinising hormone pulse frequency in ovariectomised, food-restricted ewes.

artículo científico publicado en 2011

Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related

artículo científico publicado en 2017

Neurochemical characterization and sexual dimorphism of projections from the brain to abdominal and subcutaneous white adipose tissue in the rat.

artículo científico publicado en 2012

Neuropeptide Y (NPY) delays the oestrogen-induced luteinizing hormone (LH) surge in the ovariectomized ewe: further evidence that NPY has a predominant negative effect on LH secretion in the ewe.

artículo científico publicado en 2003

Noninvasive Analytical Estimation of Endogenous GnRH Drive: Analysis Using Graded Competitive GnRH-Receptor Antagonism and a Calibrating Pulse of Exogenous GnRH

artículo científico publicado el 25 de octubre de 2011

Noradrenaline, but not neuropeptide Y, is elevated in cerebrospinal fluid from the third cerebral ventricle following audiovisual stress in gonadectomised rams and ewes.

artículo científico publicado en 2002

Ontogeny and Thermogenic Role for Sternal Fat in Female Sheep.

artículo científico publicado en 2017

Ovarian and luteal blood flow, and peripheral plasma progesterone levels, in cyclic guinea-pigs

artículo científico publicado el 1 de septiembre de 1979

Pain‐related cerebral potentials in response to acute painful electrical stimulation in sheep

artículo científico publicado el 1 de diciembre de 1997

Paracrine interactions within the pituitary gland.

artículo científico publicado en 1998

Paradoxical effect of gonadotrophin-inhibiting hormone to negatively regulate neuropeptide Y neurones in mouse arcuate nucleus.

artículo científico publicado en 2013

Peptidases that Degrade Gonadotropin‐Releasing Hormone: Influence on LH Secretion in the Ewe

artículo científico publicado el 1 de septiembre de 1997

Post-secretory processing of peptide signals: a novel mechanism for the regulation of peptide hormone receptors

artículo científico publicado el 1 de agosto de 1997

Progesterone-receptive beta-endorphin and dynorphin B neurons in the arcuate nucleus project to regions of high gonadotropin-releasing hormone neuron density in the ovine preoptic area.

artículo científico publicado en 2005

Progesterone-receptive dopaminergic and neuropeptide Y neurons project from the arcuate nucleus to gonadotropin-releasing hormone-rich regions of the ovine preoptic area.

artículo científico publicado en 2005

Projections of RFamide-related peptide-3 neurones in the ovine hypothalamus, with special reference to regions regulating energy balance and reproduction.

artículo científico publicado en 2009

Random and Non-Random Coincidence Between Luteinizing Hormone Peaks and Follicle-Stimulating Hormone, Alpha Subunit, Prolactin and Gonadotropin-Releasing Hormone ulsations.

artículo científico publicado en 1989

Rapid in vivo effects of estradiol-17beta in ovine pituitary gonadotropes are displayed by phosphorylation of extracellularly regulated kinase, serine/threonine kinase, and 3',5'-cyclic adenosine 5'-monophosphate-responsive element-binding protein.

artículo científico publicado en 2007

Reduction in adiposity affects the extent of afferent projections to growth hormone-releasing hormone and somatostatin neurons and the degree of colocalization of neuropeptides in growth hormone-releasing hormone and somatostatin cells of the ovine

scientific article published on 04 August 2005

Refractoriness to a Static Melatonin Signal Develops in the Pituitary Gland for the Control of Prolactin Secretion in the Ram

artículo científico publicado el 1 de agosto de 1997

Regulation of anterior pituitary gonadotrophin subunit mRNA levels by gonadotrophin-releasing hormone in the ewe

artículo científico publicado en 1989

Release of luteinizing hormone in androgenized ewes after prostaglandin-induced luteolysis or luteinizing hormone releasing hormone

artículo científico publicado el 1 de mayo de 1978

Response to kisspeptin and gonadotropin-releasing hormone agonist administration in Holstein-Friesian dairy heifers with positive or negative genetic merit for fertility traits

artículo científico publicado en 2022

Role of sex and sex steroids in mediating pituitary-adrenal responses to acute buspirone treatment in sheep.

artículo científico publicado en 2005

Seasonal and cyclical change in the luteinizing hormone response to kisspeptin in the ewe.

artículo científico publicado en 2009

Seasonal and steroid-dependent effects on the modulation of LH secretion in the ewe by intracerebroventricularly administered beta-endorphin or naloxone

artículo científico publicado en 1989

Sex and season are major determinants of voluntary food intake in sheep.

artículo científico publicado en 2001

Sex differences in the distribution and abundance of androgen receptor mRNA-containing cells in the preoptic area and hypothalamus of the ram and ewe.

artículo científico publicado en 2004

Sex differences in the metabolic effects of testosterone in sheep

artículo científico publicado en 2011

Sex differences in the pituitary-adrenal response following acute antidepressant treatment in sheep.

artículo científico publicado en 2003

Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model.

artículo científico publicado en 2017

Sheep model for osteoporosis: sustainability and biomechanical relevance of low turnover osteoporosis induced by hypothalamic-pituitary disconnection.

artículo científico publicado en 2013

Stimulation of growth hormone by kisspeptin antagonists in ewes

artículo científico publicado en 2018

Stress Increases Gonadotropin Inhibitory Hormone Cell Activity and Input to GnRH Cells in Ewes.

artículo científico publicado en 2016

Stress-Related Changes in beta-Endorphin Processing: The Limitations of Slaughterhouse Material

artículo científico publicado en 1989

Stress-induced behavioral and metabolic adaptations lead to an obesity-prone phenotype in ewes with elevated cortisol responses

artículo científico publicado en 2014

Stressor specificity of sex differences in hypothalamo-pituitary-adrenal axis activity: cortisol responses to exercise, endotoxin, wetting, and isolation/restraint stress in gonadectomized male and female sheep.

artículo científico publicado en 2010

Synthesis and secretion of GnRH.

artículo científico publicado en 2005

Targeting the lateral but not the third ventricle induces bone loss in ewe: an experimental approach to generate an improved large animal model of osteoporosis.

artículo científico publicado en 2012

The F0F1 ATP Synthase Complex Localizes to Membrane Rafts in Gonadotrope Cells

artículo científico publicado en 2016

The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile LH Secretion and Moderates Levels of Ovarian Hormones Throughout the Menstrual Cycle

artículo científico publicado en 2015

The action of leptin on appetite-regulating cells in the ovine hypothalamus: demonstration of direct action in the absence of the arcuate nucleus.

artículo científico publicado en 2010

The characterization, localization and regulation of endothelin in ovine pars intermedia

artículo científico publicado el 14 de mayo de 1997

The induction of fertile oestrus in seasonally anoestrous ewes using a continuous low dose administration of gonadotrophin releasing hormone

artículo científico publicado el 1 de agosto de 1983

The sexual behaviour of prenatally androgenized ewes observed in the field

artículo científico publicado el 1 de marzo de 1977

Triiodothyronine Administration in a Model of Septic Shock: A Randomized Blinded Placebo-Controlled Trial

artículo científico publicado en 2016

α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors

artículo científico publicado en 2016