Lista de obras - Germain Puzo - Dominio Público Uruguay

A glycomic approach reveals a new mycobacterial polysaccharide

artículo científico publicado en 2015

A lipomannan variant with strong TLR-2-dependent pro-inflammatory activity in Saccharothrix aerocolonigenes

artículo científico publicado en 2005

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

scientific journal article

A novel lipoarabinomannan from the equine pathogen Rhodococcus equi. Structure and effect on macrophage cytokine production

artículo científico publicado en 2002

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria

artículo científico publicado en 2012

Ac2PIM-responsive miR-150 and miR-143 target receptor-interacting protein kinase 2 and transforming growth factor beta-activated kinase 1 to suppress NOD2-induced immunomodulators

artículo científico publicado en 2015

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan

artículo científico publicado en 2007

Acylation state of the phosphatidylinositol hexamannosides from Mycobacterium bovis bacillus Calmette Guerin and mycobacterium tuberculosis H37Rv and its implication in Toll-like receptor response

artículo científico publicado en 2003

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

artículo científico publicado en 2009

Analysis of aminofluorescein-fatty acid derivatives by capillary electrophoresis with laser-induced fluorescence detection at the attomole level: application to mycobacterial fatty acids

artículo científico publicado en 2002

Assistance of microbial glycolipid antigen processing by CD1e

artículo científico publicado en 2005

Bacterial cell wall macroamphiphiles: pathogen-/microbe-associated molecular patterns detected by mammalian innate immune system

artículo científico

Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis

artículo científico publicado en 2013

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis

scientific journal article

Capillary electrophoresis analysis of glucooligosaccharide regioisomers

artículo científico publicado en 2004

Characterization of a truncated lipoarabinomannan from the Actinomycete Turicella otitidis

artículo científico publicado en 2005

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

artículo científico publicado en 2006

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

artículo científico publicado en 2011

Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation

artículo científico publicado en 2008

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

artículo científico publicado en 2005

Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes

artículo científico publicado en 2012

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

scientific journal article

Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis

artículo científico publicado en 2004

Disruption of Cg-Ppm1, a polyprenyl monophosphomannose synthase, and the generation of lipoglycan-less mutants in Corynebacterium glutamicum

artículo científico publicado en 2003

Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b

artículo científico publicado en 2006

Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response.

artículo científico publicado en 2009

Fine tuning by human CD1e of lipid-specific immune responses

artículo científico publicado en 2011

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

scientific journal article

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis

scientific journal article

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

scientific journal article

Highly ordered supra-molecular organization of the mycobacterial lipoarabinomannans in solution. Evidence of a relationship between supra-molecular organization and biological activity

artículo científico publicado en 2004

Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea

artículo científico publicado en 2003

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation

artículo científico publicado en 2009

Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species

scientific journal article

Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria

artículo científico publicado en 2009

Innate immune response of alveolar macrophage to house dust mite allergen is mediated through TLR2/-4 co-activation

artículo científico publicado en 2013

Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells

artículo científico publicado en 2007

Lipid-restricted recognition of mycobacterial lipoglycans by human pulmonary surfactant protein A: a surface-plasmon-resonance study

artículo científico publicado en 2002

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

artículo científico publicado en 2012

Lipoarabinomannans: from structure to biosynthesis

artículo científico publicado en 2003

Lipoglycans contribute to innate immune detection of mycobacteria

artículo científico publicado en 2011

Lipoteichoic acid in Streptomyces hygroscopicus: structural model and immunomodulatory activities

artículo científico publicado en 2011

Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens

artículo científico publicado en 2016

MS/MS approach for characterization of the fatty acid distribution on mycobacterial phosphatidyl-myo-inositol mannosides

artículo científico publicado en 2006

Mannan chain length controls lipoglycans signaling via and binding to TLR2.

artículo científico publicado en 2008

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

artículo científico publicado en 2013

Mycobacterial envelope lipids fingerprint from direct MALDI-TOF MS analysis of intact bacilli

artículo científico publicado en 2014

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response

artículo científico publicado en 2002

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression

artículo científico publicado en 2009

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan ⬇️

artículo científico publicado en 2010

Mycobacterium tuberculosis phoP mutant: lipoarabinomannan molecular structure

scientific journal article

Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells

artículo científico publicado en 2009

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

artículo científico publicado en 2011

PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling

artículo científico publicado en 2009

PIM2 induced MMP-9 expression in macrophages requires PI3K and Notch1 signaling.

artículo científico publicado en 2012

SOCS3 expression induced by PIM2 requires PKC and PI3K signaling

artículo científico publicado en 2009

Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues: chain length is essential for high antigenicity

artículo científico publicado en 2013

Structural analysis of mycobacterial lipoglycans

artículo científico publicado en 2004

Structural and functional features of Rhodococcus ruber lipoarabinomannan

artículo científico publicado en 2003

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

artículo científico publicado en 2011

Synthesis of diacylated trehalose sulfates: candidates for a tuberculosis vaccine

artículo científico publicado en 2008

The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.

artículo científico publicado en 2006

The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments

artículo científico publicado en 2009

The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan

artículo científico publicado en 2002

The immunomodulatory lipoglycans, lipoarabinomannan and lipomannan, are exposed at the mycobacterial cell surface

artículo científico publicado en 2008

Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans

artículo científico publicado en 2004

Tsukamurella paurometabola lipoglycan, a new lipoarabinomannan variant with pro-inflammatory activity

artículo científico publicado en 2004

Lista de obras de Germain Puzo

A glycomic approach reveals a new mycobacterial polysaccharide

A lipomannan variant with strong TLR-2-dependent pro-inflammatory activity in Saccharothrix aerocolonigenes

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

A novel lipoarabinomannan from the equine pathogen Rhodococcus equi. Structure and effect on macrophage cytokine production

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria

Ac2PIM-responsive miR-150 and miR-143 target receptor-interacting protein kinase 2 and transforming growth factor beta-activated kinase 1 to suppress NOD2-induced immunomodulators

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan

Acylation state of the phosphatidylinositol hexamannosides from Mycobacterium bovis bacillus Calmette Guerin and mycobacterium tuberculosis H37Rv and its implication in Toll-like receptor response

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

Analysis of aminofluorescein-fatty acid derivatives by capillary electrophoresis with laser-induced fluorescence detection at the attomole level: application to mycobacterial fatty acids

Assistance of microbial glycolipid antigen processing by CD1e

Bacterial cell wall macroamphiphiles: pathogen-/microbe-associated molecular patterns detected by mammalian innate immune system

Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis

Capillary electrophoresis analysis of glucooligosaccharide regioisomers

Characterization of a truncated lipoarabinomannan from the Actinomycete Turicella otitidis

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis

Disruption of Cg-Ppm1, a polyprenyl monophosphomannose synthase, and the generation of lipoglycan-less mutants in Corynebacterium glutamicum

Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b

Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response.

Fine tuning by human CD1e of lipid-specific immune responses

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

Highly ordered supra-molecular organization of the mycobacterial lipoarabinomannans in solution. Evidence of a relationship between supra-molecular organization and biological activity

Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation

Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species

Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria

Innate immune response of alveolar macrophage to house dust mite allergen is mediated through TLR2/-4 co-activation

Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells

Lipid-restricted recognition of mycobacterial lipoglycans by human pulmonary surfactant protein A: a surface-plasmon-resonance study

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

Lipoarabinomannans: from structure to biosynthesis

Lipoglycans contribute to innate immune detection of mycobacteria

Lipoteichoic acid in Streptomyces hygroscopicus: structural model and immunomodulatory activities

Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens

MS/MS approach for characterization of the fatty acid distribution on mycobacterial phosphatidyl-myo-inositol mannosides

Mannan chain length controls lipoglycans signaling via and binding to TLR2.

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

Mycobacterial envelope lipids fingerprint from direct MALDI-TOF MS analysis of intact bacilli

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan ⬇️

Mycobacterium tuberculosis phoP mutant: lipoarabinomannan molecular structure

Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling

PIM2 induced MMP-9 expression in macrophages requires PI3K and Notch1 signaling.

SOCS3 expression induced by PIM2 requires PKC and PI3K signaling

Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues: chain length is essential for high antigenicity

Structural analysis of mycobacterial lipoglycans

Structural and functional features of Rhodococcus ruber lipoarabinomannan

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

Synthesis of diacylated trehalose sulfates: candidates for a tuberculosis vaccine

The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.

The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments

The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan

The immunomodulatory lipoglycans, lipoarabinomannan and lipomannan, are exposed at the mycobacterial cell surface

Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans

Tsukamurella paurometabola lipoglycan, a new lipoarabinomannan variant with pro-inflammatory activity