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Lista de obras de Anirban Maitra

'Diseases Desperate Grown by Desperate Appliance Are Relieved, or Not at all' - Towards Finding a Cure for Pancreatic Cancer, Where Do We Stand Today?

artículo científico publicado en 2018

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

artículo científico publicado en 2016

4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.

artículo científico publicado en 2017

A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms

scientific article published on 28 June 2018

A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice

artículo científico publicado en 2014

A New Scalpel for the Treatment of Pancreatic Cancer: Targeting Stromal-Derived STAT3 Signaling

artículo científico publicado en 2015

A Phase I Study of Dinaciclib in Combination With MK-2206 in Patients With Advanced Pancreatic Cancer

scientific article published on 01 August 2020

A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer

scientific article published on 01 April 2019

A Prospective Study to Establish a New-Onset Diabetes Cohort: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer

artículo científico publicado en 2018

A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma

scientific article published on 06 August 2018

A broad survey of cathepsin K immunoreactivity in human neoplasms

scientific article published on February 2013

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy

artículo científico publicado el 1 de junio de 2012

A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.

artículo científico publicado en 2009

A draft map of the human proteome

artículo científico publicado en 2014

A microfluidic device for label-free isolation of tumor cell clusters from unprocessed blood samples

scientific article published on 01 July 2019

A new mouse model of pancreatic cancer: PTEN gets its Akt together

artículo científico publicado en 2005

A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients

artículo científico publicado en 2017

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma

artículo científico publicado en 2014

A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination

scientific article published on 06 February 2019

A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists

artículo científico publicado en 2011

A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.

artículo científico publicado en 2011

A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human hepatocellular carcinoma

artículo científico publicado en 2015

A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors

artículo científico publicado el 1 de marzo de 2011

A proteomic analysis of human bile

artículo científico publicado en 2004

A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells

artículo científico publicado en 2009

A subset of pancreatic adenocarcinomas demonstrates coamplification of topoisomerase IIalpha and HER2/neu: use of immunolabeling and multicolor FISH for potential patient screening andtreatment

scientific article published on 01 January 2005

AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health

scientific article published on 01 December 2018

Aberrant Hypermethylation of Tumor Suppressor Genes in Pancreatic Endocrine Neoplasms

artículo científico publicado el 1 de septiembre de 2003

Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma

artículo científico publicado en 2010

Aberrant expression of maspin in idiopathic inflammatory bowel disease is associated with disease activity and neoplastic transformation

artículo científico

Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms

artículo científico publicado el 1 de septiembre de 2003

Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines

artículo científico publicado en 2002

Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy

artículo científico publicado en 2008

Agents targeting the Hedgehog pathway for pancreatic cancer treatment

artículo científico publicado el 1 de diciembre de 2010

Allele-specific expression in the germline of patients with familial pancreatic cancer: an unbiased approach to cancer gene discovery

artículo científico publicado en 2007

Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways

artículo científico publicado en 2017

Altered telomeres in tumors with ATRX and DAXX mutations

artículo científico publicado en 2011

An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors.

artículo científico publicado en 2004

An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration

artículo científico publicado en 2014

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

artículo científico publicado en 2004

An in vivo platform for translational drug development in pancreatic cancer

scientific article published on 01 August 2006

An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome

artículo científico publicado en 2006

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

artículo científico publicado en 2008

Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays

artículo científico publicado en 2004

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer.

artículo científico publicado en 2018

Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors

artículo científico publicado en 2008

Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer

artículo científico publicado en 2005

Assessment of celecoxib pharmacodynamics in pancreatic cancer

artículo científico publicado en 2006

Assessment of gefitinib- and CI-1040-mediated changes in epidermal growth factor receptor signaling in HuCCT-1 human cholangiocarcinoma by serial fine needle aspiration

artículo científico publicado en 2006

Association of Clinical Factors With a Major Pathologic Response Following Preoperative Therapy for Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2017

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations

artículo científico publicado en 2014

Bile Ducts and Ductules Are Positive for CD56 (N-CAM) in Most Cases of Extrahepatic Biliary Atresia

artículo científico publicado el 1 de noviembre de 2003

Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach

artículo científico publicado en 2006

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

artículo científico publicado en 2007

CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target.

artículo científico publicado en 2005

CEACAM6 is a novel biomarker in pancreatic adenocarcinoma and PanIN lesions

artículo científico publicado en 2005

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations

artículo científico publicado en 2018

Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma.

artículo científico publicado en 2015

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

artículo científico publicado en 2019

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

artículo científico publicado en 2019

Characterization and Comparison of GITR Expression in Solid Tumors

artículo científico publicado en 2019

Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer

scientific article published on 19 September 2018

Circulating Tumor Cells and Transforming Growth Factor Beta in Resected Pancreatic Adenocarcinoma

scientific article published on 03 June 2019

Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions

artículo científico publicado en 2006

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

artículo científico publicado en 2015

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas

artículo científico publicado en 2012

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

artículo científico publicado en 2013

Clinicopathological correlation of radiologic measurement of post-therapy tumor size and tumor volume for pancreatic ductal adenocarcinoma

artículo científico publicado en 2020

Combination of PD1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer

scientific article published on 13 March 2020

Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.

artículo científico publicado en 2015

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

artículo científico publicado en 2017

Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer

artículo científico publicado en 2019

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

scientific article published on 11 January 2019

Comprehensive Proteomic Analysis of Human Pancreatic Juice

article

Computed Tomography-Based Biomarker Outcomes in a Prospective Trial of Preoperative FOLFIRINOX and Chemoradiation for Borderline Resectable Pancreatic Cancer

scientific article published on 23 August 2019

Conceptual framework for cutting the pancreatic cancer fuel supply

artículo científico

Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications

artículo científico publicado en 2005

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

artículo científico publicado en 2005

Concurrent versus sequential sorafenib therapy in combination with radiation for hepatocellular carcinoma

artículo científico publicado en 2013

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

artículo científico publicado en 2012

Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma

artículo científico publicado el 15 de julio de 2012

Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer

artículo científico publicado en 2008

Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification

artículo científico publicado en 2008

Copy-number variants in patients with a strong family history of pancreatic cancer

article

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

artículo científico publicado en 2008

Correction: Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis

article

Cost-effectiveness of consensus guideline-based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective

artículo científico publicado en 2020

Current Status and Future Directions for Screening Patients at High Risk for Pancreatic Cancer

artículo científico publicado en 2017

Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models

artículo científico publicado el 1 de octubre de 2011

Cyclooxygenase 2 expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia: an immunohistochemical analysis with automated cellular imaging

artículo científico publicado en 2002

Cystic precursors to invasive pancreatic cancer

artículo científico publicado el 1 de marzo de 2011

Cytogenetic characterization and gene expression profiling in the rat reflux-induced esophageal tumor model.

artículo científico publicado en 2007

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

artículo científico publicado en 2011

DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer

artículo científico publicado en 2013

DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma

artículo científico publicado en 2012

Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real World Endoscopic Aspiration Samples

artículo científico publicado en 2020

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

artículo científico publicado en 2014

Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.

artículo científico publicado en 2002

Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer

artículo científico publicado en 2011

Diagnostic value of digital droplet polymerase chain reaction and digital multiplexed detection of single nucleotide varients in pancreatic cytology specimens collected by EUS-guided FNA

artículo científico publicado en 2020

Differences in survival for patients with resectable versus unresectable metastases from pancreatic islet cell cancer.

artículo científico publicado en 2006

Differential membrane proteomics using 18O-labeling to identify biomarkers for cholangiocarcinoma

artículo científico publicado en 2008

Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression

artículo científico publicado en 2004

Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function

artículo científico publicado en 2019

Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.

artículo científico publicado en 2003

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

artículo científico publicado en 2002

Disputed Paternity: The Uncertain Ancestry of Pancreatic Ductal Neoplasia

artículo científico publicado el 11 de diciembre de 2012

Dual mitogen-activated protein kinase and epidermal growth factor receptor inhibition in biliary and pancreatic cancer

artículo científico publicado en 2007

Dynamic changes during the treatment of pancreatic cancer

artículo científico publicado en 2018

EMT and dissemination precede pancreatic tumor formation

artículo científico publicado en 2012

EMT: Matter of Life or Death?

artículo científico publicado en 2016

ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer.

artículo científico publicado en 2016

Early Detection of Pancreatic Cancer: Opportunities and Challenges

artículo científico publicado en 2019

Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy

artículo científico publicado en 2020

Early Detection of Sporadic Pancreatic Ductal Adenocarcinoma: Problems, Promise, and Prospects

scientific article published on 17 March 2020

Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas

artículo científico publicado en 2011

Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma

artículo científico publicado en 2011

Emerging molecular biology of pancreatic cancer

artículo científico publicado en 2008

Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model

scientific journal article

Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents

artículo científico publicado en 2005

Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth

artículo científico publicado en 2014

Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer

artículo científico publicado en 2009

Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line

artículo científico publicado en 2008

Establishment and validation of real-time polymerase chain reaction method for CDH1 promoter methylation

artículo científico publicado en 2002

Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma.

artículo científico publicado en 2004

Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

artículo científico publicado en 2003

Evolution of cellular morpho-phenotypes in cancer metastasis.

artículo científico publicado en 2015

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

artículo científico publicado en 2013

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

artículo científico publicado en 2009

Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity

artículo científico publicado en 2019

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

artículo científico publicado en 2016

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

artículo científico publicado en 2003

Expression and Clinical Significance of Protein Kinase RNA-Like Endoplasmic Reticulum Kinase and Phosphorylated Eukaryotic Initiation Factor 2α in Pancreatic Ductal Adenocarcinoma

scientific article published on 01 March 2019

Expression and prognostic significance of 14-3-3sigma and ERM family protein expression in periampullary neoplasms

artículo científico publicado en 2005

Expression of Epithelial-Mesenchymal Transition Markers in Treated Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2019

Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract

artículo científico publicado en 2004

Expression of novel markers of pancreatic ductal adenocarcinoma in pancreatic nonductal neoplasms: additional evidence of different genetic pathways

artículo científico publicado en 2005

Expression of the caudal-type homeodomain transcription factors CDX 1/2 and outcome in carcinomas of the ampulla of Vater

artículo científico publicado en 2005

Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2019

Fatal toxicity of chloroquine or hydroxychloroquine with metformin in mice

artículo científico publicado en 2020

First-Line Gemcitabine and Nab-Paclitaxel Chemotherapy for Localized Pancreatic Ductal Adenocarcinoma

article

Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma

artículo científico publicado en 2002

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

artículo científico publicado en 2007

Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts

artículo científico publicado el 1 de octubre de 2011

Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.

artículo científico publicado en 2003

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct

artículo científico publicado en 2012

GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".

artículo científico publicado en 2014

GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling

artículo científico publicado en 2018

Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): a clinicopathologic study and review

scientific article published on December 2007

Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

artículo científico publicado en 2011

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

artículo científico publicado en 2005

Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas

artículo científico publicado en 2004

Gene expression profiling identifies markers of ampullary adenocarcinoma

artículo científico publicado en 2004

Generation and testing of clinical-grade exosomes for pancreatic cancer.

artículo científico publicado en 2018

Genetic mutations associated with cigarette smoking in pancreatic cancer

artículo científico publicado en 2009

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity

artículo científico publicado en 2012

Genetics and biology of pancreatic ductal adenocarcinoma

artículo científico publicado en 2016

Genetics and pathology of pancreatic cancer

artículo científico publicado en 2006

Genome-wide aberrations in pancreatic adenocarcinoma.

artículo científico publicado en 2005

Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis.

artículo científico publicado en 2007

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

artículo científico publicado en 2013

Genomic alterations in cultured human embryonic stem cells

artículo científico publicado en 2005

Genomic analyses identify molecular subtypes of pancreatic cancer

artículo científico publicado en 2016

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

artículo científico publicado en 2017

Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer

artículo científico publicado en 2008

Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.

artículo científico publicado en 2003

HLA-G upregulation in pre-malignant and malignant lesions of the gastrointestinal tract

artículo científico publicado en 2005

HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma

artículo científico publicado en 2009

HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma

artículo científico publicado en 2008

Hear Pancreatic Cancer Stem Cells ROR

artículo científico publicado en 2019

Hedgehog signaling is required for effective regeneration of exocrine pancreas

artículo científico publicado en 2008

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

artículo científico publicado en 2004

Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer

scientific article published on 20 January 2020

Hepatocellular carcinomas show abnormal expression of fibronectin protein

scientific article published on 01 August 2002

Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics

artículo científico publicado en 2014

High prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer

artículo científico publicado en 2018

Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.

artículo científico publicado en 2003

Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy

artículo científico publicado en 2005

Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers

artículo científico publicado en 2005

Human Correlates of Provocative Questions in Pancreatic Pathology

artículo científico publicado el 1 de noviembre de 2012

Human embryonic stem cells have a unique epigenetic signature

artículo científico publicado en 2006

Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas

artículo científico publicado en 2012

Hypermutation In Pancreatic Cancer

artículo científico publicado en 2016

Identification and analysis of precursors to invasive pancreatic cancer

scientific article published on 01 January 2013

Identification and analysis of precursors to invasive pancreatic cancer.

artículo científico publicado en 2005

Identification and characterization of membralin, a novel tumor-associated gene, in ovarian carcinoma

artículo científico publicado en 2005

Identification of novel cellular targets in biliary tract cancers using global gene expression technology

artículo científico publicado en 2003

Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags

artículo científico publicado en 2004

Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma.

scientific article published on 17 February 2015

Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays

artículo científico publicado en 2006

Imaging Axl expression in pancreatic and prostate cancer xenografts

artículo científico publicado en 2013

Imaging pancreatic cancer using bioconjugated InP quantum dots

artículo científico publicado en 2009

Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection

artículo científico publicado en 2020

Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy

artículo científico publicado en 2018

Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells

artículo científico publicado en 2018

Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions

scientific article published on 01 April 2003

Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47

scientific article published on 01 July 2002

Immunotherapy for Pancreatic Cancer: More Than Just a Gut Feeling.

artículo científico publicado en 2018

Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth

artículo científico publicado en 2011

Impact of hypofractionated and standard fractionated chemoradiation before pancreatoduodenectomy for pancreatic ductal adenocarcinoma

artículo científico publicado en 2016

In vitro models of pancreatic cancer for translational oncology research

artículo científico publicado en 2009

In vivo and in vitro propagation of intraductal papillary mucinous neoplasms

artículo científico publicado en 2010

In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities

artículo científico publicado en 2008

In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video).

artículo científico publicado en 2013

Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancer

artículo científico publicado en 2011

Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients

artículo científico publicado en 2009

Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation

artículo científico publicado el 1 de noviembre de 2003

Influence of Preoperative Therapy on Short- and Long-Term Outcomes of Patients with Adenocarcinoma of the Ampulla of Vater

artículo científico publicado en 2017

Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling

artículo científico publicado en 2010

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

artículo científico publicado en 2010

Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer

artículo científico publicado en 2013

Intercepting Pancreatic Cancer: Our Dream Team's Resolve to Stop Pancreatic Cancer

scholarly article published in Pancreas

Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer

artículo científico publicado en 2014

Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk

artículo científico publicado en 2018

Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk popul

artículo científico publicado en 2012

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

artículo científico publicado en 2016

Isolation and mutational assessment of pancreatic cancer extracellular vesicles using a microfluidic platform

artículo científico publicado en 2020

Johns Hopkins course: 8th annual Current Topics in Gastrointestinal and Liver Pathology

artículo científico publicado en 2009

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

artículo científico publicado en 2019

Lead-time trajectory of CA19-9 as an anchor marker for pancreatic cancer early detection

artículo científico publicado en 2020

Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer

artículo científico publicado en 2009

Liquid biopsies in pancreatic cancer

artículo científico publicado en 2019

Liver metastases arising from well-differentiated pancreatic endocrine neoplasms demonstrate increased VEGF-C expression

scientific article published on 01 July 2003

Long interspersed element-1 protein expression is a hallmark of many human cancers

scientific article published on 06 March 2014

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

artículo científico publicado en 2016

Loss of ARID1A promotes epithelial-mesenchymal transition and sensitizes pancreatic tumors to proteotoxic stress

artículo científico publicado en 2020

Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors

artículo científico publicado en 2012

Loss of HNF6 expression correlates with human pancreatic cancer progression

artículo científico publicado en 2014

Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms

scientific article published on 01 July 2003

Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas

artículo científico publicado en 2011

Loss of heterozygosity analysis of cutaneous melanoma and benign melanocytic nevi: laser capture microdissection demonstrates clonal genetic changes in acquired nevocellular nevi

artículo científico

Loss of p27 Nuclear Expression in a Prognostically Favorable Subset of Well-Differentiated Pancreatic Endocrine Neoplasms

artículo científico publicado el 1 de noviembre de 2003

MAGE1 is expressed by a subset of pancreatic endocrine neoplasms and associated lymph node and liver metastases

artículo científico publicado en 2003

MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts

artículo científico publicado en 2011

MKK4 status predicts survival after resection of gastric adenocarcinoma

artículo científico publicado en 2006

Mac-2-binding protein is a diagnostic marker for biliary tract carcinoma

scientific article published on 01 October 2004

Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.

artículo científico publicado en 2013

Melanoma hyperpigmentation is strongly associated with KIT alterations

artículo científico publicado en 2009

Mesothelin is a specific biomarker of invasive cancer in the Barrett-associated adenocarcinoma progression model: translational implications for diagnosis and therapy

artículo científico publicado en 2008

Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms

artículo científico publicado en 2004

MicroRNA 223 is upregulated in the multistep progression of Barrett's esophagus and modulates sensitivity to chemotherapy by targeting PARP1

artículo científico publicado en 2013

MicroRNA miR-155 is a biomarker of early pancreatic neoplasia

artículo científico publicado en 2009

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.

artículo científico publicado en 2009

Mitochondrial DNA as a cancer biomarker

artículo científico publicado en 2005

Mitochondrial DNA mutations in pancreatic cancer

artículo científico publicado en 2006

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer

artículo científico publicado en 2006

Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer

artículo científico publicado en 2019

Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer

artículo científico publicado en 2007

Molecular Characteristics of Pancreatic Ductal Adenocarcinoma

artículo científico publicado el 27 de marzo de 2011

Molecular Determinants of Retinoic Acid Sensitivity in Pancreatic Cancer

artículo científico publicado el 18 de octubre de 2011

Molecular and Genetic Basis of Pancreatic Carcinogenesis: Which Concepts May be Clinically Relevant?

artículo científico publicado en 2016

Molecular genetics of pancreatic ductal adenocarcinomas and recent implications for translational efforts

artículo científico publicado en 2008

Molecular genetics of pancreatic intraepithelial neoplasia

artículo científico publicado en 2007

Molecular pathogenesis of pancreatic cancer

scientific article published on 01 April 2006

Morphogenesis of pancreatic cancer: role of pancreatic intraepithelial neoplasia (PanINs)

artículo científico publicado en 2008

Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon.

artículo científico publicado en 2012

Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray

artículo científico publicado en 2003

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

artículo científico publicado en 2020

Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer.

artículo científico publicado en 2006

Mutant proteins as cancer-specific biomarkers

artículo científico publicado en 2011

Neuroprotective and Neurorescue Effects of a Novel Polymeric Nanoparticle Formulation of Curcumin (NanoCurc™) in the Neuronal Cell Culture and Animal Model: Implications for Alzheimer's disease

artículo científico publicado el 1 de enero de 2011

New insights into plasticity of pancreatic cancer: cancer to acinar cell reprogramming by the basic helix-loop-helix transcription factor E47.

artículo científico publicado en 2015

New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.

artículo científico publicado en 2008

Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis

scientific article published on 01 June 2003

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.

artículo científico publicado en 2013

Novel markers of pancreatic adenocarcinoma in fine-needle aspiration: mesothelin and prostate stem cell antigen labeling increases accuracy in cytologically borderline cases

artículo científico publicado en 2003

Obesity, Intrapancreatic Fatty Infiltration, and Pancreatic Cancer.

artículo científico publicado en 2015

Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas.

artículo científico publicado en 2008

Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment

artículo científico publicado en 2020

Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia

artículo científico publicado en 2014

Optimizing the development of targeted agents in pancreatic cancer: tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays

scientific article published on 01 February 2007

Overexpression of ankyrin1 promotes pancreatic cancer cell growth.

artículo científico publicado en 2016

Overexpression of claudin proteins in esophageal adenocarcinoma and its precursor lesions

artículo científico publicado en 2006

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

artículo científico publicado en 2007

Pancreatic Cancer Database: an integrative resource for pancreatic cancer

artículo científico publicado en 2014

Pancreatic cancer

artículo científico publicado en 2002

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

artículo científico publicado en 2012

Pancreatic cancer in 2017: Rebooting pancreatic cancer knowledge and treatment options

artículo científico publicado en 2018

Pancreatic cancer.

artículo científico publicado en 2008

Pancreatic carcinogenesis

artículo científico publicado en 2008

Pancreatic duct stenosis secondary to small endocrine neoplasms: a manifestation of serotonin production?

artículo científico publicado en 2010

Pancreatic intraepithelial neoplasia

artículo científico publicado en 2004

Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis: of mice and men.

artículo científico publicado en 2009

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

artículo científico publicado en 2006

Pdx1 expression in pancreatic precursor lesions and neoplasms

artículo científico publicado en 2011

Performance of mitochondrial DNA mutations detecting early stage cancer

artículo científico publicado en 2008

Personalized chemotherapy profiling using cancer cell lines from selectable mice

artículo científico publicado en 2013

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

artículo científico publicado el 6 de diciembre de 2010

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma

artículo científico publicado en 2019

Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.

artículo científico publicado en 2013

Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas

artículo científico publicado en 2020

Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy

artículo científico publicado en 2007

Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma

artículo científico publicado el 25 de agosto de 2011

Positive immunohistochemical staining of KIT in solid-pseudopapillary neoplasms of the pancreas is not associated with KIT/PDGFRA mutations

artículo científico publicado en 2006

Potentially Curable Pancreatic Adenocarcinoma: ASCO Clinical Practice Guideline Update

scientific article published on 10 June 2019

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

scientific article published on 01 February 2019

Precursor lesions of pancreatic cancer: molecular pathology and clinical implications

artículo científico publicado en 2007

Precursors to invasive pancreatic cancer

artículo científico publicado en 2005

Precursors to pancreatic cancer

artículo científico publicado en 2007

Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience

artículo científico publicado en 2016

Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic Cancer

artículo científico publicado el 30 de junio de 2011

Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer

artículo científico publicado en 2011

Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia

artículo científico publicado en 2012

Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes

artículo científico publicado en 2011

Prognostic Significance of New AJCC Tumor Stage in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Therapy

artículo científico publicado en 2017

Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemotherapy

artículo científico publicado en 2017

Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer

artículo científico publicado en 2016

Prognostic significance of maspin in pancreatic ductal adenocarcinoma: tissue microarray analysis of 223 surgically resected cases

artículo científico publicado en 2007

Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma

artículo científico publicado en 2010

Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms.

artículo científico publicado en 2003

Progression of Gene Hypermethylation in Gallstone Disease Leading to Gallbladder Cancer

artículo científico publicado el 1 de octubre de 2003

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma

artículo científico publicado en 2014

Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation

artículo científico publicado en 2016

Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization

artículo científico publicado en 2016

Quality of life impact of EUS in patients at risk for developing pancreatic cancer

artículo científico publicado en 2020

Quantitative imaging to evaluate malignant potential of IPMNs

artículo científico publicado en 2016

Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: initial imaging in experimental models of pancreatic cancer

artículo científico publicado en 2007

Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer

artículo científico publicado en 2020

Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs).

artículo científico publicado en 2012

Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers

scientific article published on 02 March 2019

Recent advances in genomic profiling of adenosquamous carcinoma of the pancreas

artículo científico publicado en 2017

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

artículo científico publicado en 2011

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma

artículo científico publicado en 2017

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

scientific journal article

Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice.

artículo científico publicado en 2011

Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma

artículo científico publicado en 2012

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

artículo científico publicado en 2009

SMURF1 amplification promotes invasiveness in pancreatic cancer

artículo científico publicado en 2011

Selected topics in the evaluation of pediatric gastrointestinal mucosal biopsies

artículo científico publicado en 2009

Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer

scientific article published on 01 May 2019

Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer

artículo científico publicado en 2015

Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer

artículo científico publicado en 2017

Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer

artículo científico publicado en 2008

Sialofucosylated podocalyxin is a functional E- and L-selectin ligand expressed by metastatic pancreatic cancer cells

artículo científico publicado en 2012

Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy.

artículo científico publicado en 2018

Single Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression

artículo científico publicado en 2018

Smad4 overexpression in hepatocellular carcinoma is strongly associated with transforming growth factor beta II receptor immunolabeling

artículo científico publicado en 2002

Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors

artículo científico publicado en 2012

Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer

artículo científico publicado en 2017

Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration

artículo científico publicado en 2008

Snail and Sonic Hedgehog activation in neuroendocrine tumors of the ileum

artículo científico publicado en 2007

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

artículo científico publicado en 2011

Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

artículo científico publicado en 2008

Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma

artículo científico publicado en 2012

Subtyping Pancreatic Cancer

artículo científico publicado en 2015

Superior Mesenteric Artery Margin of Posttherapy Pancreaticoduodenectomy and Prognosis in Patients With Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2015

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer

artículo científico publicado el 1 de noviembre de 2012

Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer

artículo científico publicado en 2016

Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making?

scientific article published on 28 August 2018

Survival after gastric adenocarcinoma resection: eighteen-year experience at a single institution

artículo científico publicado en 2005

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

scientific article published on 27 March 2019

Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.

artículo científico publicado en 2010

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

artículo científico publicado en 2017

Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.

artículo científico publicado en 2010

Systemic delivery of curcumin: 21st century solutions for an ancient conundrum

artículo científico publicado en 2009

Target discovery and validation in pancreatic cancer

artículo científico publicado en 2007

Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer

artículo científico publicado en 2008

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas

artículo científico publicado en 2014

Targeting chemokine pathways in esophageal adenocarcinoma

artículo científico publicado en 2014

Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein

artículo científico publicado en 2007

Telomere length variation in biliary tract metaplasia, dysplasia, and carcinoma

scientific article published on 01 June 2006

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

artículo científico publicado en 2002

The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis.

artículo científico publicado en 2009

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

artículo científico publicado en 2009

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

artículo científico publicado en 2010

The HMGA1-COX-2 axis: A key molecular pathway and potential target in pancreatic adenocarcinoma

artículo científico publicado el 29 de mayo de 2012

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

artículo científico publicado en 2010

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.

artículo científico publicado en 2004

The V599E BRAF mutation is uncommon in biliary tract cancers

artículo científico publicado en 2004

The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer

artículo científico publicado en 2009

The emerging roles of F-box proteins in pancreatic tumorigenesis

artículo científico

The epidermal growth factor receptor HER2 is not a major therapeutic target in Ewing sarcoma

artículo científico

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma

artículo científico publicado en 2017

The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models

artículo científico publicado en 2012

The hedgehog pathway and pancreatic cancer

scientific article published on 01 November 2009

The microRNAs, MiR-31 and MiR-375, as candidate markers in Barrett's esophageal carcinogenesis

artículo científico publicado en 2012

The number and ratio of positive lymph nodes affect pancreatic cancer patient survival after neoadjuvant therapy and pancreaticoduodenectomy

artículo científico publicado en 2015

The role of stromal cancer-associated fibroblasts in pancreatic cancer.

artículo científico publicado en 2017

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

artículo científico publicado en 2015

Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin.

artículo científico publicado en 2017

Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer.

artículo científico publicado en 2011

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

artículo científico publicado en 2016

Tumor targeting and imaging in live animals with functionalized semiconductor quantum rods

artículo científico publicado en 2009

Tumor-initiating cells are rare in many human tumors

artículo científico publicado en 2010

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer

artículo científico publicado en 2011

Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology

artículo científico publicado en 2009

Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole melanoma syndrome (FAMMM).

artículo científico publicado en 2008

Update on pancreatic intraepithelial neoplasia.

artículo científico publicado en 2008

Upfront molecular profiling of pancreatic cancer patients - An idea whose time has come

scientific article published on 05 February 2020

Utility of bile duct brushings for the early detection of cholangiocarcinoma in patients with primary sclerosing cholangitis

artículo científico publicado en 2006

Validation of a Proposed Tumor Regression Grading Scheme for Pancreatic Ductal Adenocarcinoma After Neoadjuvant Therapy as a Prognostic Indicator for Survival

artículo científico publicado en 2016

Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis

artículo científico publicado en 2015

Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy

artículo científico publicado el 7 de febrero de 2012

Whole genomes redefine the mutational landscape of pancreatic cancer

artículo científico publicado en 2015

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

artículo científico publicado en 2011

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation

artículo científico publicado en 2014

Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis

artículo científico publicado el 31 de marzo de 2011

Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia

artículo científico publicado en 2009

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

artículo científico publicado el 14 de septiembre de 2003

YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma

artículo científico publicado en 2019

miR-181c regulates the mitochondrial genome, bioenergetics, and propensity for heart failure in vivo

artículo científico publicado en 2014

miRNA Biomarkers in Cyst Fluid Augment the Diagnosis and Management of Pancreatic Cysts

artículo científico publicado el 21 de junio de 2012

p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia.

artículo científico publicado en 2016

p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas

artículo científico publicado en 2014

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

scientific article published on 01 February 2019

β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis

artículo científico publicado en 2015