Lista de obras - Cornelis F.M. Sier - Dominio Público Uruguay

5-Aminosalicylic acid inhibits TGF-beta1 signalling in colorectal cancer cells.

artículo científico publicado en 2009

A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer.

artículo científico publicado en 2019

Active TGF-beta1 correlates with myofibroblasts and malignancy in the colorectal adenoma-carcinoma sequence

scientific article published on 01 April 2009

Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma

artículo científico publicado en 2020

Association of aneuploidy in index adenomas with metachronous colorectal adenoma development and a comparison

artículo científico publicado en 1992

Beta-glucan enhanced killing of renal cell carcinoma micrometastases by monoclonal antibody G250 directed complement activation.

artículo científico publicado en 2004

Biomarker expression in rectal cancer tissue before and after neoadjuvant therapy

artículo científico publicado en 2018

Bone healing and mannose-binding lectin

artículo científico publicado en 2013

Circulating bone morphogenetic protein levels and delayed fracture healing.

artículo científico publicado en 2012

Clinical applications of the urokinase receptor (uPAR) for cancer patients.

artículo científico publicado en 2011

Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer

scientific article published on 02 July 2007

Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer.

artículo científico publicado en 2006

Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer

artículo científico publicado en 2014

Comparative evaluation of carcinoembryonic antigen, secretory component, and mucins in index and metachronous adenomas of the colorectum

artículo científico publicado en 1991

Correlation Between Preoperative Serum Carcinoembryonic Antigen Levels and Expression on Pancreatic and Rectal Cancer Tissue.

artículo científico publicado en 2017

Correlation of glutathione S-transferases with overall survival in patients with gastric carcinoma

artículo científico publicado en 1996

Cytoplasmic Overexpression of HER2: a Key Factor in Colorectal Cancer.

artículo científico publicado en 2013

Determination of matrilysin activity in gastrointestinal neoplasia

scientific article published on 01 July 2007

Displaced midshaft fractures of the clavicle: non-operative treatment versus plate fixation (Sleutel-TRIAL). A multicentre randomised controlled trial.

artículo científico publicado en 2011

EGFR and αvβ6 as Promising Targets for Molecular Imaging of Cutaneous and Mucosal Squamous Cell Carcinoma of the Head and Neck Region

artículo científico publicado en 2020

EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma

artículo científico publicado en 2006

Efficient degradation-aided selection of protease inhibitors by phage display.

artículo científico publicado en 2007

Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis

artículo científico publicado en 2018

Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer.

artículo científico publicado en 2016

Endothelium specific matrilysin (MMP-7) expression in human cancers.

artículo científico publicado en 2007

Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers

artículo científico publicado en 2000

EpCAM as multi-tumour target for near-infrared fluorescence guided surgery.

artículo científico publicado en 2016

Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels

artículo científico publicado en 2007

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery.

artículo científico publicado en 2017

Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer

artículo científico publicado en 2020

Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases

scientific article published on 01 August 2005

Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study

artículo científico publicado en 2014

Fluorescence- and multispectral optoacoustic imaging for an optimized detection of deeply located tumors in an orthotopic mouse model of pancreatic carcinoma

artículo científico publicado en 2017

Fluorescence-guided tumor detection with a novel anti-EpCAM targeted antibody fragment: Preclinical validation

scientific article published on 23 October 2018

Gastric mucosal plasminogen activators in Helicobacter pylori infection

artículo científico publicado en 1996

Glutathione S-transferase pi in colorectal tumors is predictive for overall survival

artículo científico publicado en 1995

Glutathione S-transferases in liver metastases of colorectal cancer. A comparison with normal liver and primary carcinomas.

artículo científico publicado en 1994

Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study

artículo científico publicado en 2020

ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer

scientific article published on 04 September 2019

Identification of cell-surface markers for detecting breast cancer cells in ovarian tissue.

artículo científico publicado en 2016

Implant removal associated complications in children with limb fractures due to trauma.

artículo científico publicado en 2011

In Search for Optimal Targets for Intraoperative Fluorescence Imaging of Peritoneal Metastasis From Colorectal Cancer.

artículo científico publicado en 2017

Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis

article by Cornelis F.M. Sier et al published November 1994 in Gastroenterology

Increased expression of cancer-associated fibroblast markers at the invasive front and its association with tumor-stroma ratio in colorectal cancer

scientific article published on 29 March 2019

Increased mucosal matrix metalloproteinase-1, -2, -3 and -9 activity in patients with inflammatory bowel disease and the relation with Crohn's disease phenotype

artículo científico publicado en 2007

Increased urokinase receptor levels in human gastrointestinal neoplasia and related liver metastases.

artículo científico publicado en 1993

Injury pattern, injury severity, and mortality in 33,495 hospital-admitted victims of motorized two-wheeled vehicle crashes in The Netherlands.

artículo científico publicado en 2012

Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts ⬇️

artículo científico publicado el 3 de diciembre de 2012

Introducing fluorescence guided surgery into orthopedic oncology: A systematic review of candidate protein targets for Ewing sarcoma

artículo científico publicado en 2018

MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.

artículo científico publicado en 2012

MMP-9 activity in urine from patients with various tumors, as measured by a novel MMP activity assay using modified urokinase as a substrate

artículo científico publicado en 1999

Matrix metalloproteinases and their tissue inhibitors as prognostic indicators for diagnostic and surgical recurrence in Crohn's disease

artículo científico publicado en 2009

Metabolism of tumour-derived urokinase receptor and receptor fragments in cancer patients and xenografted mice.

artículo científico publicado en 2004

Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer

artículo científico publicado en 2020

Molecular targets for diagnostic and intraoperative imaging of pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX treatment

scientific article published on 01 October 2020

Morphological and phenotypical features of ovarian metastases in breast cancer patients.

artículo científico publicado en 2017

Novel Molecular Targets for Tumor-Specific Imaging of Epithelial Ovarian Cancer Metastases

artículo científico publicado en 2020

PAI-1 inhibits urokinase-induced chemotaxis by internalizing the urokinase receptor

scientific article published on 01 September 2001

Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage.

artículo científico publicado en 2001

Plasminogen activators in normal tissue and carcinomas of the human oesophagus and stomach

artículo científico publicado en 1993

Potential targets for tumor-specific imaging of vulvar squamous cell carcinoma: A systematic review of candidate biomarkers

scientific article published on 09 January 2020

Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors.

artículo científico publicado en 2015

Preclinical uPAR-targeted multimodal imaging of locoregional oral cancer.

artículo científico publicado en 2017

Presence of urokinase-type plasminogen activator receptor in urine of cancer patients and its possible clinical relevance

scientific article published on 01 June 1999

Prognostic Impact of Urokinase Plasminogen Activator Receptor Expression in Pancreatic Cancer: Malignant Versus Stromal Cells.

artículo científico publicado en 2017

Prognostic relevance of plasminogen activators and their inhibitors in colorectal cancer.

artículo científico publicado en 1994

Prognostic value of plasminogen activators and their inhibitors in colorectal cancer.

artículo científico publicado en 1995

Prognostic value of the plasminogen activation system in patients with gastric carcinoma

artículo científico publicado en 1996

Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types

artículo científico publicado en 2017

Reply to the letter to the editor: Could the use of bone morphogenetic proteins in fracture healing do more harm than good to our patients?

artículo científico publicado en 2011

Selecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane Proteins

artículo científico publicado en 2016

Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery

artículo científico publicado en 2016

Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma.

artículo científico publicado en 2017

Serum level of soluble urokinase-type plasminogen activator receptor is a strong and independent predictor of survival in human immunodeficiency virus infection.

artículo científico publicado en 2000

Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo

scientific article published on 01 June 2000

Soluble urokinase receptor levels correlate with number of circulating tumor cells in acute myeloid leukemia and decrease rapidly during chemotherapy

artículo científico publicado en 2000

Stromal Targets for Fluorescent-Guided Oncologic Surgery

artículo científico publicado en 2015

Superoxide dismutases in relation to the overall survival of colorectal cancer patients ⬇️

artículo científico publicado el 1 de octubre de 1998

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging

artículo científico publicado en 2020

Targeting endoglin expressing regulatory T cells in the tumor microenvironment enhances the effect of PD1 checkpoint inhibitor immunotherapy

scientific article published on 24 April 2020

Tetranectin expression in human colonic neoplasia

scientific article published on 01 November 1994

The level of urokinase-type plasminogen activator receptor is increased in serum of ovarian cancer patients

scientific article published on 01 May 1998

Tissue level, activation and cellular localisation of TGF-beta1 and association with survival in gastric cancer patients

artículo científico publicado en 2007

Urokinase receptor and colorectal cancer survival.

artículo científico publicado en 1994

Use and efficacy of bone morphogenetic proteins in fracture healing.

scientific article published on 23 June 2011

VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.

artículo científico publicado en 2008

Vitamin D in Head and Neck Cancer: a Systematic Review

artículo científico publicado en 2020

[The midshaft clavicular fracture]

artículo científico publicado en 2010

uPAR directed-imaging of head-and-neck cancer.

artículo científico publicado en 2017

uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery

artículo científico publicado en 2015

Lista de obras de Cornelis F.M. Sier

5-Aminosalicylic acid inhibits TGF-beta1 signalling in colorectal cancer cells.

A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer.

Active TGF-beta1 correlates with myofibroblasts and malignancy in the colorectal adenoma-carcinoma sequence

Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma

Association of aneuploidy in index adenomas with metachronous colorectal adenoma development and a comparison

Beta-glucan enhanced killing of renal cell carcinoma micrometastases by monoclonal antibody G250 directed complement activation.

Biomarker expression in rectal cancer tissue before and after neoadjuvant therapy

Bone healing and mannose-binding lectin

Circulating bone morphogenetic protein levels and delayed fracture healing.

Clinical applications of the urokinase receptor (uPAR) for cancer patients.

Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer

Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer.

Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer

Comparative evaluation of carcinoembryonic antigen, secretory component, and mucins in index and metachronous adenomas of the colorectum

Correlation Between Preoperative Serum Carcinoembryonic Antigen Levels and Expression on Pancreatic and Rectal Cancer Tissue.

Correlation of glutathione S-transferases with overall survival in patients with gastric carcinoma

Cytoplasmic Overexpression of HER2: a Key Factor in Colorectal Cancer.

Determination of matrilysin activity in gastrointestinal neoplasia

Displaced midshaft fractures of the clavicle: non-operative treatment versus plate fixation (Sleutel-TRIAL). A multicentre randomised controlled trial.

EGFR and αvβ6 as Promising Targets for Molecular Imaging of Cutaneous and Mucosal Squamous Cell Carcinoma of the Head and Neck Region

EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma

Efficient degradation-aided selection of protease inhibitors by phage display.

Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis

Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer.

Endothelium specific matrilysin (MMP-7) expression in human cancers.

Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers

EpCAM as multi-tumour target for near-infrared fluorescence guided surgery.

Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery.

Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer

Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases

Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study

Fluorescence- and multispectral optoacoustic imaging for an optimized detection of deeply located tumors in an orthotopic mouse model of pancreatic carcinoma

Fluorescence-guided tumor detection with a novel anti-EpCAM targeted antibody fragment: Preclinical validation

Gastric mucosal plasminogen activators in Helicobacter pylori infection

Glutathione S-transferase pi in colorectal tumors is predictive for overall survival

Glutathione S-transferases in liver metastases of colorectal cancer. A comparison with normal liver and primary carcinomas.

Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study

ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer

Identification of cell-surface markers for detecting breast cancer cells in ovarian tissue.

Implant removal associated complications in children with limb fractures due to trauma.

In Search for Optimal Targets for Intraoperative Fluorescence Imaging of Peritoneal Metastasis From Colorectal Cancer.

Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis

Increased expression of cancer-associated fibroblast markers at the invasive front and its association with tumor-stroma ratio in colorectal cancer

Increased mucosal matrix metalloproteinase-1, -2, -3 and -9 activity in patients with inflammatory bowel disease and the relation with Crohn's disease phenotype

Increased urokinase receptor levels in human gastrointestinal neoplasia and related liver metastases.

Injury pattern, injury severity, and mortality in 33,495 hospital-admitted victims of motorized two-wheeled vehicle crashes in The Netherlands.

Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts ⬇️

Introducing fluorescence guided surgery into orthopedic oncology: A systematic review of candidate protein targets for Ewing sarcoma

MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.

MMP-9 activity in urine from patients with various tumors, as measured by a novel MMP activity assay using modified urokinase as a substrate

Matrix metalloproteinases and their tissue inhibitors as prognostic indicators for diagnostic and surgical recurrence in Crohn's disease

Metabolism of tumour-derived urokinase receptor and receptor fragments in cancer patients and xenografted mice.

Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer

Molecular targets for diagnostic and intraoperative imaging of pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX treatment

Morphological and phenotypical features of ovarian metastases in breast cancer patients.

Novel Molecular Targets for Tumor-Specific Imaging of Epithelial Ovarian Cancer Metastases

PAI-1 inhibits urokinase-induced chemotaxis by internalizing the urokinase receptor

Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage.

Plasminogen activators in normal tissue and carcinomas of the human oesophagus and stomach

Potential targets for tumor-specific imaging of vulvar squamous cell carcinoma: A systematic review of candidate biomarkers

Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors.

Preclinical uPAR-targeted multimodal imaging of locoregional oral cancer.

Presence of urokinase-type plasminogen activator receptor in urine of cancer patients and its possible clinical relevance

Prognostic Impact of Urokinase Plasminogen Activator Receptor Expression in Pancreatic Cancer: Malignant Versus Stromal Cells.

Prognostic relevance of plasminogen activators and their inhibitors in colorectal cancer.

Prognostic value of plasminogen activators and their inhibitors in colorectal cancer.

Prognostic value of the plasminogen activation system in patients with gastric carcinoma

Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types

Reply to the letter to the editor: Could the use of bone morphogenetic proteins in fracture healing do more harm than good to our patients?

Selecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane Proteins

Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery

Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma.

Serum level of soluble urokinase-type plasminogen activator receptor is a strong and independent predictor of survival in human immunodeficiency virus infection.

Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo

Soluble urokinase receptor levels correlate with number of circulating tumor cells in acute myeloid leukemia and decrease rapidly during chemotherapy

Stromal Targets for Fluorescent-Guided Oncologic Surgery

Superoxide dismutases in relation to the overall survival of colorectal cancer patients ⬇️

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging