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Lista de obras de Ahmet Zehir

A FISH assay efficiently screens for BRAF gene rearrangements in pancreatic acinar-type neoplasms

artículo científico publicado en 2017

A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled By Clinical Genomic Sequencing

artículo científico publicado en 2020

A quick guide for clinical oncology

artículo científico publicado en 2021

Abstract 1387: Tracking minimal residual disease in post-operative cell-free DNA using MSK-ACCESS

scholarly article

Abstract 1672: Clinical validation of a genomics-based classifier to predict tissue of origin from targeted tumor sequencing

scholarly article

Abstract 1681: Prospective clinical sequencing distinguishes independent primary cancers from recurrent or metastatic disease

scholarly article

Abstract 1752: BRCA-mediated tumorigenesis is origin and cell-type dependent

scholarly article

Abstract 2736: A molecular and histopathologic map of cancer metastasis

scholarly article

Abstract 3409: MSK-IMPACT Heme: Validation and clinical experience of a comprehensive molecular profiling platform for hematologic malignancies

scholarly article

Abstract 4158: Dissecting the role of zygosity and lineage in Lynch Syndrome-associated microsatellite Instability

scholarly article

Abstract 729: Zygosity, lineage, and penetrance dictate the role of germline pathogenicity in tumorigenesis

scholarly article

Abstract LB-304: Oncologic therapy for solid tumors alters the risk of clonal hematopoiesis

scholarly article

Abstract PR012: Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets

artículo científico publicado en 2022

Accelerating Discovery of Functional Mutant Alleles in Cancer

artículo científico publicado en 2017

Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes

scientific article published on 08 January 2019

Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade

scientific article published on 01 April 2019

Author Correction: Tumour lineage shapes BRCA-mediated phenotypes

artículo científico publicado en 2020

BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways

scientific journal article

BRCA Mutations, Homologous DNA Repair Deficiency, Tumor Mutational Burden, and Response to Immune Checkpoint Inhibition in Recurrent Ovarian Cancer

scientific article published on 16 June 2020

Binimetinib plus Gemcitabine and Cisplatin Phase I/II Trial in Patients with Advanced Biliary Cancers

artículo científico publicado en 2018

Cancer therapy shapes the fitness landscape of clonal hematopoiesis

artículo científico publicado en 2020

Characterization and Clinical Outcomes of DNA Mismatch Repair Deficient (MMR-D) Small Bowel Adenocarcinoma

artículo científico publicado en 2020

Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival

artículo científico publicado en 2017

Clinical Genomic Sequencing of Pediatric and Adult Osteosarcoma Reveals Distinct Molecular Subsets with Potentially Targetable Alterations

artículo científico publicado en 2019

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer

artículo científico publicado en 2018

Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer

artículo científico publicado en 2018

Clinical utility of clonality testing by next generation sequencing in the monitoring of B-cell and T-cell malignancies. ⬇️

artículo científico publicado en 2017

Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center

artículo científico publicado en 2022

Clonal hematopoiesis is associated with risk of severe Covid-19

scientific article published on 27 November 2020

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

scientific article published on 14 January 2019

Comprehensive Genomic Analysis of Metastatic Non-Clear-Cell Renal Cell Carcinoma to Identify Therapeutic Targets

scientific article published on 28 April 2019

Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention

scientific article published on 30 May 2018

Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing

artículo científico publicado en 2017

Concurrent alterations in EGFR-mutant lung cancers associated with resistance to EGFR kinase inhibitors and characterization of MTOR as a mediator of resistance.

artículo científico publicado en 2018

Consistent copy number changes and recurrent PRKAR1A mutations distinguish Melanotic Schwannomas from Melanomas: SNP-array and next generation sequencing analysis

scientific article published on 29 May 2015

Detection of Tumor NTRK Gene Fusions to Identify Patients Who May Benefit from Tyrosine Kinase (TRK) Inhibitor Therapy

scientific article published on 07 May 2019

Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data.

artículo científico publicado en 2014

Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care

artículo científico publicado en 2019

Dicer is required for survival of differentiating neural crest cells

artículo científico publicado en 2010

Distance in cancer gene expression from stem cells predicts patient survival

artículo científico publicado en 2017

E-cadherin immunohistochemical expression in invasive lobular carcinoma of the breast: correlation with morphology and CDH1 somatic alterations

artículo científico publicado en 2020

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

artículo científico publicado en 2017

Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project

artículo científico publicado en 2020

Establishment of Immunoglobulin Heavy (IGH) Chain Clonality Testing by Next-Generation Sequencing for Routine Characterization of B-Cell and Plasma Cell Neoplasms

Evaluation of Initial Telomere Length and Changes after Transplantation in Adult Double-Unit Cord Blood Transplant Recipients

artículo científico publicado en 2015

Evaluation of a combined Multi-Locus Sequence Typing and Whole-Genome Sequencing Two-step Algorithm for Routine typing of Clostridioides difficile

scientific article published on 11 November 2020

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers

artículo científico publicado en 2022

Fragment Size Analysis May Distinguish Clonal Hematopoiesis from Tumor-Derived Mutations in Cell-Free DNA

scientific article published on 01 April 2020

Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma

artículo científico publicado en 2019

Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity

artículo científico publicado en 2022

Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer.

artículo científico publicado en 2017

Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response

scientific article published on 01 May 2019

Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

scientific article published on 01 October 2019

Genome doubling shapes the evolution and prognosis of advanced cancers

scientific article published on 16 July 2018

Genomic Alterations as Potential Therapeutic Targets in Extramammary Paget's Disease of the Vulva

scientific article published on 15 September 2020

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

scientific article published on 01 July 2019

Genomic Differences Between "Primary" and "Secondary" Muscle-invasive Bladder Cancer as a Basis for Disparate Outcomes to Cisplatin-based Neoadjuvant Chemotherapy

artículo científico publicado en 2018

Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma

scientific article published on 15 October 2019

Genomic Profiling Identifies Somatic Mutations Predicting Thromboembolic Risk in Patients with Solid Tumors

artículo científico publicado en 2020

Genomic aberrations frequently alter chromatin regulatory genes in chordoma

artículo científico publicado en 2016

Genotypic correlation between post discharge Clostridiodes difficile infection (CDI) and previous unit-based contacts

artículo científico publicado en 2020

Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs

artículo científico publicado en 2020

Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.

artículo científico publicado en 2015

Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer

scientific article published on 12 November 2019

Harnessing Clinical Sequencing Data for Survival Stratification of Patients with Metastatic Lung Adenocarcinomas

scientific article published on 28 March 2019

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

scientific article published on 26 April 2019

Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays

artículo científico publicado en 2018

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

scientific article published on 11 December 2015

Immunohistochemical analysis of estrogen receptor in breast cancer with ESR1 mutations detected by hybrid capture-based next-generation sequencing

artículo científico publicado en 2018

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

scientific article published on 06 July 2016

Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis

artículo científico publicado en 2021

Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma

artículo científico publicado en 2017

Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition

article

Linked Entity Attribute Pair (LEAP): A Harmonization Framework for Data Pooling

artículo científico publicado en 2020

MET exon 14-altered lung cancers and MET inhibitor resistance

artículo científico publicado en 2020

Machine learning-based prediction of microsatellite instability and high tumor mutation burden from contrast-enhanced computed tomography in endometrial cancers

artículo científico publicado en 2020

Majority of -Mutant and -Deficient Colorectal Carcinomas Achieve Clinical Benefit From Immune Checkpoint Inhibitor Therapy and Are Microsatellite Instability-High

artículo científico publicado en 2019

Managing Clonal Hematopoiesis in Patients With Solid Tumors

artículo científico publicado en 2018

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

artículo científico publicado en 2015

Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer

artículo científico publicado en 2018

Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand (PD-L)-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing

artículo científico publicado en 2018

Molecular profiling and analysis of genetic aberrations aimed at identifying potential therapeutic targets in fibrolamellar carcinoma of the liver

artículo científico publicado en 2020

Multicolor Flow Cytometry and Multigene Next-Generation Sequencing Are Complementary and Highly Predictive for Relapse in Acute Myeloid Leukemia after Allogeneic Transplantation

artículo científico publicado en 2017

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.

artículo científico publicado en 2017

Mutational Analysis of Clonal Hematopoiesis in Solid Tumor Patients Illustrates the Critical Role of Systemic Anti-Cancer Therapies in the Evolution of Somatic Leukemia Disease Alleles ⬇️

artículo científico publicado en 2016

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

artículo científico publicado en 2017

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

artículo científico publicado en 2019

Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status in Invasive Breast Carcinoma: A Focus on Group 4 Using the 2018 ASCO/CAP HER2 Testing Guideline

scientific article published on 25 August 2020

Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status: Clinical Validation in the Context of a Hybrid Capture-Based, Comprehensive Solid Tumor Genomic Profiling Assay

artículo científico publicado en 2016

Next-Generation Sequencing of Matched Normal Blood Identifies Clonal Hematopoiesis in a Significant Subset of Solid Tumor Patients without Hematologic Malignancies ⬇️

artículo científico publicado en 2015

Next-Generation Sequencing-Based Assessment of JAK2, PD-L1, and PD-L2 Copy Number Alterations at 9p24.1 in Breast Cancer: Potential Implications for Clinical Management

artículo científico publicado en 2018

Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets

artículo científico publicado en 2017

Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing.

artículo científico publicado en 2014

OncoKB: A Precision Oncology Knowledge Base

scientific article published on 16 May 2017

Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions

artículo científico publicado en 2017

Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma

artículo científico publicado en 2017

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

artículo científico publicado en 2017

Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas

artículo científico publicado en 2017

Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

scientific article published on 15 December 2013

Prevalence and Preliminary Validation of Screening Criteria to Identify Carriers of Germline BAP1 Mutations

artículo científico publicado en 2019

Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors

artículo científico publicado en 2018

Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.

artículo científico publicado en 2017

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

artículo científico publicado en 2018

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making

artículo científico publicado en 2017

Radioactive Iodine-Related Clonal Hematopoiesis in Thyroid Cancer Is Common and Associated With Decreased Survival

scientific article published on 01 November 2018

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

artículo científico publicado en 2017

Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology

artículo científico publicado en 2019

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.

scientific article published on 29 May 2016

Reliable Clinical MLH1 Promoter Hypermethylation Assessment Using a High-Throughput Genome-Wide Methylation Array Platform

artículo científico publicado en 2019

Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data

artículo científico publicado en 2017

Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes

artículo científico publicado en 2019

Single-cell mutation analysis of clonal evolution in myeloid malignancies

artículo científico publicado en 2020

Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: a retrospective analysis of data from MSK-IMPACT and TCGA

artículo científico publicado en 2018

Successful Targeted Therapy of Refractory Pediatric Fusion-Positive Secretory Breast Carcinoma

artículo científico publicado en 2017

Telomere Length Plays No Role in Clinical Unit Dominance After Double-Unit Cord Blood Transplantation ⬇️

artículo científico publicado en 2012

The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic

artículo científico publicado en 2020

The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers

artículo científico publicado en 2018

The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform.

artículo científico publicado en 2016

The Value of Cell-free DNA for Molecular Pathology

artículo científico publicado en 2018

The clinical implications of clonal hematopoiesis in hematopoietic cell transplantation

artículo científico publicado en 2020

The molecular landscape of extraskeletal osteosarcoma: A clinicopathological and molecular biomarker study

artículo científico publicado en 2015

The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement

artículo científico publicado en 2019

Therapeutic Implications of Germline Testing in Patients With Advanced Cancers

artículo científico publicado en 2021

Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes

artículo científico

Translational Bioinformatics and Clinical Research (Biomedical) Informatics.

artículo científico

Translational Bioinformatics and Clinical Research (Biomedical) Informatics.

artículo científico publicado en 2016

Tumor Mutation Burden: Promises and Challenges A Perspective from the IASLC Pathology Committee

scientific article published on 06 June 2020

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

artículo científico publicado en 2019

Tumour lineage shapes BRCA-mediated phenotypes

scientific article published on 10 July 2019

Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: new recommendations, methods, and considerations

artículo científico publicado en 2017

Variant Review with the Integrative Genomics Viewer

artículo científico publicado en 2017

Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer

artículo científico publicado en 2018

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