Lista de obras - Mark T Nelson - Dominio Público Uruguay

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

artículo científico publicado en 2014

A spoonful of sugar helps the KV channel activity go down

artículo científico publicado en 2006

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

artículo científico publicado en 2014

ATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity.

artículo científico publicado en 2008

Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels.

artículo científico publicado en 2011

Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tail

scientific article published on 01 December 1996

Activity-dependent NFATc3 nuclear accumulation in pericytes from cortical parenchymal microvessels

artículo científico publicado en 2007

Adenosine activates ATP-sensitive potassium channels in arterial myocytes via A2 receptors and cAMP-dependent protein kinase

artículo científico publicado en 1995

Amplified NO/cGMP-mediated relaxation and ryanodine receptor-to-BKCa channel signalling in corpus cavernosum smooth muscle from phospholamban knockout mice

artículo científico publicado en 2012

Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation

artículo científico publicado en 2007

Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction.

artículo científico publicado en 2010

Bayliss, myogenic tone and volume‐regulated chloride channels in arterial smooth muscle ⬇️

artículo científico publicado el 15 de marzo de 1998

Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel.

artículo científico publicado en 2008

Calcium and diabetic vascular dysfunction. Focus on "Elevated Ca(2+) sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells".

artículo científico publicado en 2009

Calcium signaling in smooth muscle.

artículo científico publicado en 2011

Calcium waves in intact guinea pig gallbladder smooth muscle cells.

artículo científico publicado en 2006

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

artículo científico publicado en 2017

Central role of Ca2+-dependent regulation of vascular tone in vivo

artículo científico publicado en 2006

Chloride channel blockers inhibit myogenic tone in rat cerebral arteries

scientific article published on 01 July 1997

Development of stress-induced bladder insufficiency requires functional TRPV1 channels

scientific article published on 08 August 2018

Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease

artículo científico publicado en 2021

Dynamic inositol trisphosphate-mediated calcium signals within astrocytic endfeet underlie vasodilation of cerebral arterioles.

artículo científico publicado en 2006

Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.

artículo científico publicado en 2012

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion

scientific article published on 26 March 2018

Endothelial SK(Ca) and IK(Ca) channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow.

artículo científico publicado en 2010

Endothelial histamine H1 receptor signaling reduces blood-brain barrier permeability and susceptibility to autoimmune encephalomyelitis.

artículo científico publicado en 2010

Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation

scientific article published on 08 March 2019

Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels

artículo científico publicado en 2006

Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections

artículo científico publicado en 2008

Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes.

artículo científico publicado en 2002

Fundamental increase in pressure-dependent constriction of brain parenchymal arterioles from subarachnoid hemorrhage model rats due to membrane depolarization.

artículo científico publicado en 2010

High blood pressure arising from a defect in vascular function.

artículo científico publicado en 2008

Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.

artículo científico publicado en 2010

Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction

artículo científico publicado en 2008

Inhibition of vascular smooth muscle inward-rectifier K+ channels restores myogenic tone in mouse urinary bladder arterioles.

artículo científico publicado en 2017

Inositol trisphosphate receptor calcium release is required for cerebral artery smooth muscle cell proliferation.

artículo científico publicado en 2005

Intermediate‐conductance calcium‐activated potassium channels participate in neurovascular coupling ⬇️

artículo científico publicado el 1 de octubre de 2011

Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase

scientific article published on 19 December 2003

Inversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca2+-activated K+ (BK) channels.

artículo científico publicado en 2012

Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators.

artículo científico publicado en 2016

Ion channels in smooth muscle: regulators of intracellular calcium and contractility.

artículo científico publicado en 2005

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle

artículo científico publicado en 2014

Local potassium signaling couples neuronal activity to vasodilation in the brain.

artículo científico publicado en 2006

Location, Location, Location: Juxtaposed calcium-signaling microdomains as a novel model of the vascular smooth muscle myogenic response

artículo científico publicado en 2015

Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation.

artículo científico publicado en 2013

Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

artículo científico publicado en 2016

Membrane depolarization mediates phosphorylation and nuclear translocation of CREB in vascular smooth muscle cells.

artículo científico publicado en 2001

Molecular coding of Kv1 channels to oppose myogenic constriction

artículo científico publicado en 2006

Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladder

scientific article published on 04 January 2007

NFAT regulation in smooth muscle

artículo científico publicado en 2003

NFATc3 regulates BK channel function in murine urinary bladder smooth muscle.

artículo científico publicado en 2008

NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions.

artículo científico publicado en 2014

Nerve-evoked purinergic signalling suppresses action potentials, Ca2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle

artículo científico publicado en 2009

Neurovascular signaling in the brain and the pathological consequences of hypertension

scientific article published on 25 October 2013

Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle

artículo científico publicado en 2002

Opposing effects of aluminum on inward-rectifier potassium currents in bean root-tip protoplasts.

artículo científico publicado en 2004

Opposing roles of smooth muscle BK channels and ryanodine receptors in the regulation of nerve-evoked constriction of mesenteric resistance arteries

artículo científico publicado en 2014

Orchestrating Ca2+ influx through Ca(V)1.2 and Ca(V)3.x channels in human cerebral arteries.

artículo científico publicado en 2015

Oxidation of cysteine 117 stimulates constitutive activation of the type Iα cGMP-dependent protein kinase

scientific article published in Journal of Biological Chemistry

PACAP38-Mediated Bladder Afferent Nerve Activity Hyperexcitability and Ca2+ Activity in Urothelial Cells from Mice

scientific article published on 19 July 2018

PIP depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

artículo científico publicado en 2018

Perturbations of the cerebrovascular matrisome: A convergent mechanism in small vessel disease of the brain?

artículo científico publicado en 2015

Pharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic mice

artículo científico publicado en 2016

Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro.

artículo científico publicado en 2009

Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.

artículo científico publicado en 2015

Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels.

artículo científico publicado en 2016

Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current.

artículo científico publicado en 2003

Properties of a tonically active, sodium-permeable current in mouse urinary bladder smooth muscle

artículo científico publicado en 2004

Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles.

artículo científico publicado en 2013

Protein kinases: tuners of the BKCa channel in smooth muscle.

artículo científico publicado en 2001

Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe.

artículo científico publicado en 2017

Purinergic signalling underlies transforming growth factor-β-mediated bladder afferent nerve hyperexcitability.

artículo científico publicado en 2016

Reduced Ca2+ spark activity after subarachnoid hemorrhage disables BK channel control of cerebral artery tone.

artículo científico publicado en 2010

Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice.

artículo científico publicado en 2016

Regulation of arterial tone by calcium-dependent K+ channels and ATP-sensitive K+ channels.

artículo científico publicado en 1993

Role for pituitary adenylate cyclase activating polypeptide in cystitis-induced plasticity of micturition reflexes

artículo científico publicado en 2005

Role of Ryanodine Type 2 Receptors in Elementary Ca Signaling in Arteries and Vascular Adaptive Responses

article

Ryanodine receptors, calcium signaling, and regulation of vascular tone in the cerebral parenchymal microcirculation.

artículo científico publicado en 2013

Small-conductance, Ca(2+) -activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder

artículo científico publicado en 2008

Social stress induces changes in urinary bladder function, bladder NGF content, and generalized bladder inflammation in mice

artículo científico publicado en 2014

Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function

artículo científico publicado en 2014

Subarachnoid blood converts neurally evoked vasodilation to vasoconstriction in rat brain cortex.

artículo científico publicado en 2013

Sympathetic nerve stimulation induces local endothelial Ca2+ signals to oppose vasoconstriction of mouse mesenteric arteries.

artículo científico publicado en 2011

TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw

artículo científico publicado en 2018

TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses.

artículo científico publicado en 2013

TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels.

artículo científico publicado en 2005

The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.

artículo científico publicado en 2015

The KV 7 channel activator retigabine suppresses mouse urinary bladder afferent nerve activity without affecting detrusor smooth muscle K+ channel currents

artículo científico publicado en 2018

Transient contractions of urinary bladder smooth muscle are drivers of afferent nerve activity during filling

artículo científico publicado en 2016

Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow.

artículo científico publicado en 2008

Transient receptor potential channels regulate myogenic tone of resistance arteries

scientific article published on 01 February 2002

Transient receptor potential vanilloid-4 channels are involved in diminished myogenic tone in brain parenchymal arterioles in response to chronic hypoperfusion in mice

scientific article published on 16 September 2018

Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1-Dependent Uncoupling of Endothelial Nitric Oxide Synthase.

artículo científico publicado en 2016

Uncoupling of neurovascular communication after transient global cerebral ischemia is caused by impaired parenchymal smooth muscle Kir channel function

artículo científico publicado en 2016

Unique properties of muscularis mucosae smooth muscle in guinea pig urinary bladder ⬇️

artículo científico publicado el 1 de junio de 2011

Vascular TRP channels: performing under pressure and going with the flow

artículo científico publicado en 2014

Vascular control of the CO2/H+ dependent drive to breathe

artículo científico publicado en 2020

Lista de obras de Mark T Nelson

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

A spoonful of sugar helps the KV channel activity go down

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

ATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity.

Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels.

Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tail

Activity-dependent NFATc3 nuclear accumulation in pericytes from cortical parenchymal microvessels

Adenosine activates ATP-sensitive potassium channels in arterial myocytes via A2 receptors and cAMP-dependent protein kinase

Amplified NO/cGMP-mediated relaxation and ryanodine receptor-to-BKCa channel signalling in corpus cavernosum smooth muscle from phospholamban knockout mice

Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation

Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction.

Bayliss, myogenic tone and volume‐regulated chloride channels in arterial smooth muscle ⬇️

Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel.

Calcium and diabetic vascular dysfunction. Focus on "Elevated Ca(2+) sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells".

Calcium signaling in smooth muscle.

Calcium waves in intact guinea pig gallbladder smooth muscle cells.

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

Central role of Ca2+-dependent regulation of vascular tone in vivo

Chloride channel blockers inhibit myogenic tone in rat cerebral arteries

Development of stress-induced bladder insufficiency requires functional TRPV1 channels

Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease

Dynamic inositol trisphosphate-mediated calcium signals within astrocytic endfeet underlie vasodilation of cerebral arterioles.

Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion

Endothelial SK(Ca) and IK(Ca) channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow.

Endothelial histamine H1 receptor signaling reduces blood-brain barrier permeability and susceptibility to autoimmune encephalomyelitis.

Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation

Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels

Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections

Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes.

Fundamental increase in pressure-dependent constriction of brain parenchymal arterioles from subarachnoid hemorrhage model rats due to membrane depolarization.

High blood pressure arising from a defect in vascular function.

Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.

Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction

Inhibition of vascular smooth muscle inward-rectifier K+ channels restores myogenic tone in mouse urinary bladder arterioles.

Inositol trisphosphate receptor calcium release is required for cerebral artery smooth muscle cell proliferation.

Intermediate‐conductance calcium‐activated potassium channels participate in neurovascular coupling ⬇️

Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase

Inversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca2+-activated K+ (BK) channels.

Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators.

Ion channels in smooth muscle: regulators of intracellular calcium and contractility.

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle

Local potassium signaling couples neuronal activity to vasodilation in the brain.

Location, Location, Location: Juxtaposed calcium-signaling microdomains as a novel model of the vascular smooth muscle myogenic response

Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation.

Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

Membrane depolarization mediates phosphorylation and nuclear translocation of CREB in vascular smooth muscle cells.

Molecular coding of Kv1 channels to oppose myogenic constriction

Morphological and physiological evidence for interstitial cell of Cajal-like cells in the guinea pig gallbladder

NFAT regulation in smooth muscle

NFATc3 regulates BK channel function in murine urinary bladder smooth muscle.

NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions.

Nerve-evoked purinergic signalling suppresses action potentials, Ca2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle

Neurovascular signaling in the brain and the pathological consequences of hypertension

Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle

Opposing effects of aluminum on inward-rectifier potassium currents in bean root-tip protoplasts.

Opposing roles of smooth muscle BK channels and ryanodine receptors in the regulation of nerve-evoked constriction of mesenteric resistance arteries

Orchestrating Ca2+ influx through Ca(V)1.2 and Ca(V)3.x channels in human cerebral arteries.

Oxidation of cysteine 117 stimulates constitutive activation of the type Iα cGMP-dependent protein kinase

PACAP38-Mediated Bladder Afferent Nerve Activity Hyperexcitability and Ca2+ Activity in Urothelial Cells from Mice

PIP depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

Perturbations of the cerebrovascular matrisome: A convergent mechanism in small vessel disease of the brain?

Pharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic mice

Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro.

Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.

Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels.

Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current.

Properties of a tonically active, sodium-permeable current in mouse urinary bladder smooth muscle

Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles.

Protein kinases: tuners of the BKCa channel in smooth muscle.

Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe.

Purinergic signalling underlies transforming growth factor-β-mediated bladder afferent nerve hyperexcitability.

Reduced Ca2+ spark activity after subarachnoid hemorrhage disables BK channel control of cerebral artery tone.

Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice.

Regulation of arterial tone by calcium-dependent K+ channels and ATP-sensitive K+ channels.

Role for pituitary adenylate cyclase activating polypeptide in cystitis-induced plasticity of micturition reflexes

Role of Ryanodine Type 2 Receptors in Elementary Ca Signaling in Arteries and Vascular Adaptive Responses

Ryanodine receptors, calcium signaling, and regulation of vascular tone in the cerebral parenchymal microcirculation.

Small-conductance, Ca(2+) -activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder