Lista de obras - Bente Vilsen - Dominio Público Uruguay

A C-terminal mutation of ATP1A3 underscores the crucial role of sodium affinity in the pathophysiology of rapid-onset dystonia-parkinsonism

artículo científico publicado en 2009

A Glu329-->Gln variant of the alpha-subunit of the rat kidney Na+,K(+)-ATPase can sustain active transport of Na+ and K+ and Na+,K(+)-activated ATP hydrolysis with normal turnover number

artículo científico publicado en 1993

A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps.

artículo científico publicado en 2011

ATP binding residues of sarcoplasmic reticulum Ca2+-ATPase.

artículo científico publicado en 2003

ATP-binding modes and functionally important interdomain bonds of sarcoplasmic reticulum Ca2+-ATPase revealed by mutation of glycine 438, glutamate 439, and arginine 678.

artículo científico publicado en 2007

Alteration of intracellular Ca2+ transients in COS-7 cells transfected with the cDNA encoding skeletal-muscle ryanodine receptor carrying a mutation associated with malignant hyperthermia

artículo científico publicado en 1994

Amino acids Asn796 and Thr799 of the Ca(2+)-ATPase of sarcoplasmic reticulum bind Ca2+ at different sites.

artículo científico publicado en 1994

Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase

artículo científico publicado en 2016

Asparagine 706 and glutamate 183 at the catalytic site of sarcoplasmic reticulum Ca2+-ATPase play critical but distinct roles in E2 states

artículo científico publicado en 2006

Asparagine 905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation

artículo científico publicado en 2019

Binding of cardiotonic steroids to Na<sup>+</sup>,K<sup>+</sup>-ATPase in the E2P state

artículo científico publicado en 2021

Ca2+ occlusion in monomeric sarcoplasmic reticulum Ca-ATPase

scientific article published on 01 January 1988

Characterization of CrATP-induced calcium occlusion in membrane-bound and soluble monomeric sarcoplasmic reticulum Ca2+-ATPase

artículo científico publicado en 1987

Characterization of detergent-solubilized sarcoplasmic reticulum Ca2+-ATPase by high-performance liquid chromatography

artículo científico publicado en 1986

Chimeric Ca(2+)-ATPase/Na+,K(+)-ATPase molecules. Their phosphoenzyme intermediates and sensitivity to Ca2+ and thapsigargin

scientific article published on 01 December 1993

CrATP-induced Ca2+ occlusion in mutants of the Ca(2+)-ATPase of sarcoplasmic reticulum

artículo científico publicado en 1992

Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2

artículo científico publicado en 2012

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.

artículo científico publicado en 2014

Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release

artículo científico publicado en 2008

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state

artículo científico publicado en 2013

Crystal structure of the sodium–potassium pump

artículo científico publicado en 2007

Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress

artículo científico publicado en 2011

Deduced amino acid sequence and E1-E2 equilibrium of the sarcoplasmic reticulum Ca(2+)-ATPase of frog skeletal muscle. Comparison with the Ca(2+)-ATPase of rabbit fast twitch muscle

artículo científico publicado en 1992

Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates.

artículo científico publicado en 2017

Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.

artículo científico publicado en 2005

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses

artículo científico publicado en 2003

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 3 isoforms by steady-state and transient kinetic analyses

artículo científico publicado en 2002

Distinct effects of Q925 mutation on intracellular and extracellular Na+ and K+ binding to the Na+, K+-ATPase

artículo científico publicado en 2019

Distinct neurological disorders with ATP1A3 mutations

artículo científico publicado en 2014

Effect of phospholipid, detergent and protein-protein interaction on stability and phosphoenzyme isomerization of soluble sarcoplasmic reticulum Ca-ATPase

artículo científico publicado en 1987

Equilibrium between monomers and oligomers of soluble Ca2+-ATPase during the functional cycle

artículo científico publicado en 1985

Fast kinetic analysis of conformational changes in mutants of the Ca(2+)-ATPase of sarcoplasmic reticulum

artículo científico publicado en 2000

Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses

artículo científico publicado en 2005

Functional consequences of alterations to Glu309, Glu771, and Asp800 in the Ca(2+)-ATPase of sarcoplasmic reticulum ⬇️

artículo científico publicado el 25 de septiembre de 1992

Functional consequences of alterations to Gly310, Gly770, and Gly801 located in the transmembrane domain of the Ca(2+)-ATPase of sarcoplasmic reticulum.

artículo científico publicado en 1992

Functional consequences of alterations to Ile279, Ile283, Glu284, His285, Phe286, and His288 in the NH2-terminal part of transmembrane helix M3 of the Na+,K(+)-ATPase

artículo científico publicado en 2003

Functional consequences of alterations to Pro328 and Leu332 located in the 4th transmembrane segment of the alpha-subunit of the rat kidney Na+,K(+)-ATPase

artículo científico publicado en 1992

Functional consequences of alterations to amino acids located in the hinge domain of the Ca(2+)-ATPase of sarcoplasmic reticulum

artículo científico publicado en 1991

Functional consequences of alterations to hydrophobic amino acids located at the M4S4 boundary of the Ca(2+)-ATPase of sarcoplasmic reticulum

scientific article published on 01 October 1991

Functional consequences of alterations to hydrophobic amino acids located in the M4 transmembrane sector of the Ca(2+)-ATPase of sarcoplasmic reticulum.

artículo científico publicado en 1993

Functional consequences of charge reversals of acidic residues in M1 of the SR Ca-ATPase.

artículo científico publicado en 2003

Functional consequences of mutation Asn326-->Leu in the 4th transmembrane segment of the alpha-subunit of the rat kidney Na+, K(+)-ATPase.

artículo científico publicado en 1995

Functional consequences of mutations in the beta-strand sector of the Ca2(+)-ATPase of sarcoplasmic reticulum

artículo científico publicado en 1989

Functional consequences of mutations in the transmembrane core region for cation translocation and energy transduction in the Na+,K(+)-ATPase and the SR Ca(2+)-ATPase

artículo científico publicado en 1997

Functional consequences of proline mutations in the cytoplasmic and transmembrane sectors of the Ca2(+)-ATPase of sarcoplasmic reticulum

artículo científico publicado en 1989

Functional consequences of substitution of the seven-residue segment LysIleArgAspGlnMetAla240 located in the stalk helix S3 of the Ca(2+)-ATPase of sarcoplasmic reticulum

scientific article published on 01 September 1993

Functional consequences of the CAPOS mutation E818K of Na,K-ATPase

artículo científico publicado en 2018

Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice.

artículo científico publicado en 2012

Germline De Novo Mutations in ATP1A1 Cause Renal Hypomagnesemia, Refractory Seizures, and Intellectual Disability

artículo científico publicado en 2018

Glutamate 329 located in the fourth transmembrane segment of the alpha-subunit of the rat kidney Na+,K+-ATPase is not an essential residue for active transport of sodium and potassium ions.

artículo científico publicado en 1993

Glutamate transporter activity promotes enhanced Na+ /K+ -ATPase-mediated extracellular K+ management during neuronal activity.

artículo científico publicado en 2016

Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions

artículo científico publicado en 2004

Identification and function of a cytoplasmic K+ site of the Na+, K+ -ATPase.

artículo científico publicado en 2008

Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes

artículo científico publicado en 2002

Importance of Leu99 in transmembrane segment M1 of the Na+, K+ -ATPase in the binding and occlusion of K+

artículo científico publicado en 2007

Importance of Thr214 in the conserved TGES sequence of the Na+,K+-ATPase for vanadate binding and hydrolysis of E2P.

artículo científico publicado en 2003

Importance of a Potential Protein Kinase A Phosphorylation Site of Na+,K+-ATPase and Its Interaction Network for Na+ Binding

artículo científico publicado en 2016

Importance of conserved N-domain residues Thr441, Glu442, Lys515, Arg560, and Leu562 of sarcoplasmic reticulum Ca2+-ATPase for MgATP binding and subsequent catalytic steps. Plasticity of the nucleotide-binding site

artículo científico publicado en 2003

Importance of conserved Thr214 in domain A of the Na+,K+ -ATPase for stabilization of the phosphoryl transition state complex in E2P dephosphorylation

scientific journal article

Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing

artículo científico publicado en 2004

Importance of transmembrane segment M3 of Na+,K+-ATPase for control of conformational changes and the cytoplasmic entry pathway for Na

scientific article published on 01 April 2003

Importance of transmembrane segment M3 of the sarcoplasmic reticulum Ca2+-ATPase for control of the gateway to the Ca2+ sites

artículo científico publicado en 2001

Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine

artículo científico publicado en 2011

Interaction between the catalytic site and the A-M3 linker stabilizes E2/E2P conformational states of Na+,K+-ATPase.

artículo científico publicado en 2004

Interaction of nucleotides with Asp(351) and the conserved phosphorylation loop of sarcoplasmic reticulum Ca(2+)-ATPase

artículo científico publicado en 1999

Interdependence of Ca2+ occlusion sites in the unphosphorylated sarcoplasmic reticulum Ca(2+)-ATPase complex with CrATP.

artículo científico publicado en 1992

Leucine 332 at the Boundary Between the Fourth Transmembrane Segment and the Cytoplasmic Domain of Na+,K+-ATPase Plays a Pivotal Role in the Ion Translocating Conformational Changes ⬇️

artículo científico publicado el 28 de octubre de 1997

Localization of E1-E2 conformational transitions of sarcoplasmic reticulum Ca-ATPase by tryptic cleavage and hydrophobic labeling

artículo científico publicado en 1986

Localization of a K+ -binding site involved in dephosphorylation of the sarcoplasmic reticulum Ca2+ -ATPase.

artículo científico publicado en 2004

Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump

artículo científico publicado en 2011

Molecular cloning and characterization of porcine Na⁺/K⁺-ATPase isoforms α1, α2, α3 and the ATP1A3 promoter

artículo científico publicado en 2013

Molecular cloning, functional expression and tissue distribution of the cDNA encoding frog skeletal muscle calsequestrin

artículo científico publicado en 1992

Mutagenesis of Sarcoplasmic Reticulum Ca(2+)-ATPase

artículo científico publicado en 1998

Mutagenesis of residues involved in control of the Ca2+ entry pathway and conformational changes associated with Ca2+ binding in the SR Ca2+-ATPase.

artículo científico publicado en 2003

Mutagenesis of segment 487Phe-Ser-Arg-Asp-Arg-Lys492 of sarcoplasmic reticulum Ca2+-ATPase produces pumps defective in ATP binding

artículo científico publicado en 1996

Mutant Glu781-->Ala of the rat kidney Na+,K(+)-ATPase displays low cation affinity and catalyzes ATP hydrolysis at a high rate in the absence of potassium ions.

artículo científico publicado en 1995

Mutant Phe788 --> Leu of the Na+,K+-ATPase is inhibited by micromolar concentrations of potassium and exhibits high Na+-ATPase activity at low sodium concentrations

artículo científico publicado en 1999

Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.

artículo científico publicado en 2009

Mutation Lys758 → Ile of the Sarcoplasmic Reticulum Ca2+-ATPase Enhances Dephosphorylation ofE 2 P and Inhibits theE 2 to E 1Ca2Transition ⬇️

artículo científico publicado el 28 de noviembre de 1997

Mutation of Gly-94 in transmembrane segment M1 of Na+,K+-ATPase interferes with Na+ and K+ binding in E2P conformation

artículo científico publicado en 2005

Mutation to the glutamate in the fourth membrane segment of Na+,K+-ATPase and Ca2+-ATPase affects cation binding from both sides of the membrane and destabilizes the occluded enzyme forms

artículo científico publicado en 1998

Mutational analysis of the role of Glu309 in the sarcoplasmic reticulum Ca(2+)-ATPase of frog skeletal muscle

artículo científico publicado en 1992

Mutational analysis of the role of Lys684 in the Ca(2+)-ATPase of sarcoplasmic reticulum

artículo científico publicado en 1992

Mutational effects on conformational changes of the dephospho- and phospho-forms of the Na+,K+-ATPase.

artículo científico publicado en 2001

Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.

artículo científico publicado en 2006

Neurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function.

artículo científico publicado en 2016

Occlusion of 22Na+ and 86Rb+ in membrane-bound and soluble protomeric alpha beta-units of Na,K-ATPase

artículo científico publicado en 1988

Occlusion of 22Na+ and 86Rb+ in membrane-bound and soluble protomeric alpha beta-units of Na,K-ATPase

scientific article published on 01 January 1988

Occlusion of 22Na+ and 86Rb+ in membrane-bound and soluble protomeric alpha beta-units of Na,K-ATPase

artículo científico publicado en 1987

Occlusion of Ca2+ in soluble monomeric sarcoplasmic reticulum Ca2+-ATPase

scientific article published on 01 March 1986

Overview: subunit interaction and conformational states. Ca-ATPase and Na,K-ATPase compared.

artículo científico publicado en 1988

P-type ATPases as drug targets: tools for medicine and science.

artículo científico publicado en 2009

Primary ion pumps

scientific article published on August 1990

Radiation inactivation analysis of sarcoplasmic reticulum Ca-ATPase in membrane-bound form and in detergent-solubilized monomeric states

artículo científico publicado en 1988

Reaction of phenylhydrazine with erythrocytes. Cross-linking of spectrin by disulfide exchange with oxidized hemoglobin

artículo científico publicado en 1984

Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease

artículo científico publicado en 2013

Rescue of Na+ affinity in aspartate 928 mutants of Na+,K+-ATPase by secondary mutation of glutamate 314.

artículo científico publicado en 2015

Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase

artículo científico publicado en 2004

Roles of transmembrane segment M1 of Na+,K+-ATPase and Ca2-ATPase, the gatekeeper and the pivot.

artículo científico publicado en 2007

Site‐Directed Mutagenesis Analysis of the Role of the M5S5 Sector of the Sarcoplasmic Reticulum Ca2+‐ATPasea ⬇️

artículo científico publicado el 3 de noviembre de 1997

Somatic ATP1A1, ATP2B3, and KCNJ5 mutations in aldosterone-producing adenomas

artículo científico publicado en 2013

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

artículo científico publicado en 2013

Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit

artículo científico publicado en 2015

Structural basis for the E1/E1P-E2/E2P conformation changes in the sarcoplasmic reticulum Ca(2+)-ATPase studied by site-specific mutagenesis

artículo científico publicado en 1992

Structure-function relationships in the Ca(2+)-ATPase of sarcoplasmic reticulum studied by use of the substrate analogue CrATP and site-directed mutagenesis. Comparison with the Na+,K(+)-ATPase

artículo científico publicado en 1995

Structure-function relationships of cation translocation by Ca(2+)- and Na+, K(+)-ATPases studied by site-directed mutagenesis.

artículo científico publicado en 1995

Structure-function relationships of the calcium binding sites of the sarcoplasmic reticulum Ca(2+)-ATPase

artículo científico publicado el 1 de agosto de 1998

The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.

artículo científico publicado en 2009

The Na+,K+ pump continues to cause surprise

artículo científico publicado en 2008

The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site

artículo científico publicado en 2010

The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations

artículo científico publicado en 2009

The α2β2 isoform combination dominates the astrocytic Na(+) /K(+) -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation.

artículo científico

Transmembrane segment M3 is essential to thapsigargin sensitivity of the sarcoplasmic reticulum Ca(2+)-ATPase

artículo científico publicado en 1994

Use of a small TSK GSW high-performance liquid chromatographic column for large-zone chromatographic studies of monomer-oligomer equilibria of membrane protein

scientific article published on 01 June 1988

Lista de obras de Bente Vilsen

A C-terminal mutation of ATP1A3 underscores the crucial role of sodium affinity in the pathophysiology of rapid-onset dystonia-parkinsonism

A Glu329-->Gln variant of the alpha-subunit of the rat kidney Na+,K(+)-ATPase can sustain active transport of Na+ and K+ and Na+,K(+)-activated ATP hydrolysis with normal turnover number

A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps.

ATP binding residues of sarcoplasmic reticulum Ca2+-ATPase.

ATP-binding modes and functionally important interdomain bonds of sarcoplasmic reticulum Ca2+-ATPase revealed by mutation of glycine 438, glutamate 439, and arginine 678.

Alteration of intracellular Ca2+ transients in COS-7 cells transfected with the cDNA encoding skeletal-muscle ryanodine receptor carrying a mutation associated with malignant hyperthermia

Amino acids Asn796 and Thr799 of the Ca(2+)-ATPase of sarcoplasmic reticulum bind Ca2+ at different sites.

Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase

Asparagine 706 and glutamate 183 at the catalytic site of sarcoplasmic reticulum Ca2+-ATPase play critical but distinct roles in E2 states

Asparagine 905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation

Binding of cardiotonic steroids to Na<sup>+</sup>,K<sup>+</sup>-ATPase in the E2P state

Ca2+ occlusion in monomeric sarcoplasmic reticulum Ca-ATPase

Characterization of CrATP-induced calcium occlusion in membrane-bound and soluble monomeric sarcoplasmic reticulum Ca2+-ATPase

Characterization of detergent-solubilized sarcoplasmic reticulum Ca2+-ATPase by high-performance liquid chromatography

Chimeric Ca(2+)-ATPase/Na+,K(+)-ATPase molecules. Their phosphoenzyme intermediates and sensitivity to Ca2+ and thapsigargin

CrATP-induced Ca2+ occlusion in mutants of the Ca(2+)-ATPase of sarcoplasmic reticulum

Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.

Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state

Crystal structure of the sodium–potassium pump

Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress

Deduced amino acid sequence and E1-E2 equilibrium of the sarcoplasmic reticulum Ca(2+)-ATPase of frog skeletal muscle. Comparison with the Ca(2+)-ATPase of rabbit fast twitch muscle

Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates.

Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 3 isoforms by steady-state and transient kinetic analyses

Distinct effects of Q925 mutation on intracellular and extracellular Na+ and K+ binding to the Na+, K+-ATPase

Distinct neurological disorders with ATP1A3 mutations

Effect of phospholipid, detergent and protein-protein interaction on stability and phosphoenzyme isomerization of soluble sarcoplasmic reticulum Ca-ATPase

Equilibrium between monomers and oligomers of soluble Ca2+-ATPase during the functional cycle

Fast kinetic analysis of conformational changes in mutants of the Ca(2+)-ATPase of sarcoplasmic reticulum

Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses

Functional consequences of alterations to Glu309, Glu771, and Asp800 in the Ca(2+)-ATPase of sarcoplasmic reticulum ⬇️

Functional consequences of alterations to Gly310, Gly770, and Gly801 located in the transmembrane domain of the Ca(2+)-ATPase of sarcoplasmic reticulum.

Functional consequences of alterations to Ile279, Ile283, Glu284, His285, Phe286, and His288 in the NH2-terminal part of transmembrane helix M3 of the Na+,K(+)-ATPase

Functional consequences of alterations to Pro328 and Leu332 located in the 4th transmembrane segment of the alpha-subunit of the rat kidney Na+,K(+)-ATPase

Functional consequences of alterations to amino acids located in the hinge domain of the Ca(2+)-ATPase of sarcoplasmic reticulum

Functional consequences of alterations to hydrophobic amino acids located at the M4S4 boundary of the Ca(2+)-ATPase of sarcoplasmic reticulum

Functional consequences of alterations to hydrophobic amino acids located in the M4 transmembrane sector of the Ca(2+)-ATPase of sarcoplasmic reticulum.

Functional consequences of charge reversals of acidic residues in M1 of the SR Ca-ATPase.

Functional consequences of mutation Asn326-->Leu in the 4th transmembrane segment of the alpha-subunit of the rat kidney Na+, K(+)-ATPase.

Functional consequences of mutations in the beta-strand sector of the Ca2(+)-ATPase of sarcoplasmic reticulum

Functional consequences of mutations in the transmembrane core region for cation translocation and energy transduction in the Na+,K(+)-ATPase and the SR Ca(2+)-ATPase

Functional consequences of proline mutations in the cytoplasmic and transmembrane sectors of the Ca2(+)-ATPase of sarcoplasmic reticulum

Functional consequences of substitution of the seven-residue segment LysIleArgAspGlnMetAla240 located in the stalk helix S3 of the Ca(2+)-ATPase of sarcoplasmic reticulum

Functional consequences of the CAPOS mutation E818K of Na,K-ATPase

Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice.

Germline De Novo Mutations in ATP1A1 Cause Renal Hypomagnesemia, Refractory Seizures, and Intellectual Disability

Glutamate 329 located in the fourth transmembrane segment of the alpha-subunit of the rat kidney Na+,K+-ATPase is not an essential residue for active transport of sodium and potassium ions.

Glutamate transporter activity promotes enhanced Na+ /K+ -ATPase-mediated extracellular K+ management during neuronal activity.

Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions

Identification and function of a cytoplasmic K+ site of the Na+, K+ -ATPase.

Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes

Importance of Leu99 in transmembrane segment M1 of the Na+, K+ -ATPase in the binding and occlusion of K+

Importance of Thr214 in the conserved TGES sequence of the Na+,K+-ATPase for vanadate binding and hydrolysis of E2P.

Importance of a Potential Protein Kinase A Phosphorylation Site of Na+,K+-ATPase and Its Interaction Network for Na+ Binding

Importance of conserved N-domain residues Thr441, Glu442, Lys515, Arg560, and Leu562 of sarcoplasmic reticulum Ca2+-ATPase for MgATP binding and subsequent catalytic steps. Plasticity of the nucleotide-binding site

Importance of conserved Thr214 in domain A of the Na+,K+ -ATPase for stabilization of the phosphoryl transition state complex in E2P dephosphorylation

Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing

Importance of transmembrane segment M3 of Na+,K+-ATPase for control of conformational changes and the cytoplasmic entry pathway for Na

Importance of transmembrane segment M3 of the sarcoplasmic reticulum Ca2+-ATPase for control of the gateway to the Ca2+ sites

Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine

Interaction between the catalytic site and the A-M3 linker stabilizes E2/E2P conformational states of Na+,K+-ATPase.

Interaction of nucleotides with Asp(351) and the conserved phosphorylation loop of sarcoplasmic reticulum Ca(2+)-ATPase

Interdependence of Ca2+ occlusion sites in the unphosphorylated sarcoplasmic reticulum Ca(2+)-ATPase complex with CrATP.

Leucine 332 at the Boundary Between the Fourth Transmembrane Segment and the Cytoplasmic Domain of Na+,K+-ATPase Plays a Pivotal Role in the Ion Translocating Conformational Changes ⬇️

Localization of E1-E2 conformational transitions of sarcoplasmic reticulum Ca-ATPase by tryptic cleavage and hydrophobic labeling

Localization of a K+ -binding site involved in dephosphorylation of the sarcoplasmic reticulum Ca2+ -ATPase.

Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump

Molecular cloning and characterization of porcine Na⁺/K⁺-ATPase isoforms α1, α2, α3 and the ATP1A3 promoter

Molecular cloning, functional expression and tissue distribution of the cDNA encoding frog skeletal muscle calsequestrin

Mutagenesis of Sarcoplasmic Reticulum Ca(2+)-ATPase

Mutagenesis of residues involved in control of the Ca2+ entry pathway and conformational changes associated with Ca2+ binding in the SR Ca2+-ATPase.

Mutagenesis of segment 487Phe-Ser-Arg-Asp-Arg-Lys492 of sarcoplasmic reticulum Ca2+-ATPase produces pumps defective in ATP binding

Mutant Glu781-->Ala of the rat kidney Na+,K(+)-ATPase displays low cation affinity and catalyzes ATP hydrolysis at a high rate in the absence of potassium ions.

Mutant Phe788 --> Leu of the Na+,K+-ATPase is inhibited by micromolar concentrations of potassium and exhibits high Na+-ATPase activity at low sodium concentrations

Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.

Mutation Lys758 → Ile of the Sarcoplasmic Reticulum Ca2+-ATPase Enhances Dephosphorylation ofE 2 P and Inhibits theE 2 to E 1Ca2Transition ⬇️