Lista de obras - Shigenobu Shibata - Dominio Público Uruguay

2,2,2-Tribromoethanol Phase-Shifts the Circadian Rhythm of the Liver Clock in Per2::Luciferase Knockin Mice: Lack of Dependence on Anesthetic Activity ⬇️

artículo científico publicado el 13 de diciembre de 2011

A balanced diet is necessary for proper entrainment signals of the mouse liver clock

artículo científico publicado en 2009

A low-protein diet eliminates the circadian rhythm of serum insulin and hepatic lipid metabolism in mice

artículo científico publicado en 2018

A role of nociceptin in the entrainment mechanism of the biological clock

artículo científico publicado en 2005

A single daily meal at the beginning of the active or inactive period inhibits food deprivation-induced fatty liver in mice

artículo científico publicado en 2014

Abnormal tuning of the hepatic circadian metabolic rhythms in lung cancer

artículo científico publicado en 2016

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

artículo científico publicado en 2014

Adrenergic regulation of clock gene expression in mouse liver

artículo científico publicado en 2003

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.

artículo científico publicado en 2017

Age-related circadian disorganization caused by sympathetic dysfunction in peripheral clock regulation

artículo científico publicado en 2017

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice

artículo científico publicado en 2005

Anatomical cross-sectional area of the quadriceps femoris and sit-to-stand test score in middle-aged and elderly population: development of a predictive equation

artículo científico publicado en 2016

Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model

artículo científico publicado en 2015

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

artículo científico publicado en 2015

Association of body mass index-related single nucleotide polymorphisms with psychiatric disease and memory performance in a Japanese population

artículo científico publicado en 2016

Attenuated Food Anticipatory Activity and Abnormal Circadian Locomotor Rhythms in Rgs16 Knockdown Mice ⬇️

artículo científico publicado el 9 de marzo de 2011

Attenuating effect of clock mutation on triglyceride contents in the ICR mouse liver under a high-fat diet

artículo científico publicado en 2007

Basic and applied science of chrononutrition ⬇️

artículo científico publicado el 1 de marzo de 2011

Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1.

artículo científico publicado en 2014

Ca2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin

artículo científico publicado en 2002

Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver

artículo científico publicado en 2004

Chrono-biology, chrono-pharmacology, and chrono-nutrition

artículo científico

Chrono-nutrition and n-3 polyunsaturated fatty acid

artículo científico publicado en 2018

Circadian Clock mutation in dams disrupts nursing behavior and growth of pups

artículo científico publicado en 2006

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice

artículo científico publicado en 2015

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function.

artículo científico publicado en 2018

Circadian clock gene Period2 regulates a time-of-day–dependent variation in cutaneous anaphylactic reaction ⬇️

artículo científico publicado el 1 de abril de 2011

Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice

artículo científico publicado en 2017

Circadian regulation of allergic reactions by the mast cell clock in mice

artículo científico publicado en 2013

Circadian rhythms in the CNS and peripheral clock disorders: preface

artículo científico publicado en 2007

Circadian rhythms in the CNS and peripheral clock disorders: the circadian clock and hyperlipidemia

artículo científico publicado en 2007

Circadian rhythms of liver physiology and disease: experimental and clinical evidence

artículo científico publicado en 2016

Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet

artículo científico publicado en 2007

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response

artículo científico publicado en 2017

Combination of meal and exercise timing with a high-fat diet influences energy expenditure and obesity in mice

artículo científico publicado en 2014

Constant light housing during nursing causes human DSPS (delayed sleep phase syndrome) behaviour in Clock-mutant mice

artículo científico publicado en 2007

Controlling access time to a high-fat diet during the inactive period protects against obesity in mice.

artículo científico publicado en 2014

Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.

artículo científico publicado en 2010

Daily injection of insulin attenuated impairment of liver circadian clock oscillation in the streptozotocin-treated diabetic mouse

artículo científico publicado en 2004

Dietary intake is associated with human chronotype as assessed by both morningness–eveningness score and preferred midpoint of sleep in young Japanese women ⬇️

artículo científico publicado el 18 de abril de 2011

Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation

artículo científico publicado en 2016

Differential effect of lithium on the circadian oscillator in young and old hamsters

artículo científico publicado en 2007

Differential roles of breakfast only (one meal per day) and a bigger breakfast with a small dinner (two meals per day) in mice fed a high-fat diet with regard to induced obesity and lipid metabolism ⬇️

artículo científico publicado el 15 de mayo de 2012

Disruption of the suprachiasmatic nucleus blunts a time of day-dependent variation in systemic anaphylactic reaction in mice

artículo científico publicado en 2014

Eating meals before wheel-running exercise attenuate high fat diet-driven obesity in mice under two meals per day schedule.

artículo científico publicado en 2015

Effect of chronic ethanol exposure on the liver of Clock-mutant mice

artículo científico publicado en 2009

Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei

artículo científico publicado en 2004

Effect of quetiapine on Per1, Per2, and Bmal1 clock gene expression in the mouse amygdala and hippocampus

artículo científico publicado en 2014

Effects of Meal Timing on Postprandial Glucose Metabolism and Blood Metabolites in Healthy Adults

Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice

artículo científico publicado en 2014

Effects of medial hypothalamic lesions on feeding-induced entrainment of locomotor activity and liver Per2 expression in Per2::luc mice

artículo científico publicado en 2010

Entrainment of mouse peripheral circadian clocks to <24 h feeding/fasting cycles under 24 h light/dark conditions

artículo científico publicado en 2015

Entrainment of the mouse circadian clock by sub-acute physical and psychological stress

artículo científico publicado en 2015

Entrainment of the mouse circadian clock: Effects of stress, exercise, and nutrition

artículo científico publicado en 2017

Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis

artículo científico publicado en 2014

Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice

artículo científico publicado en 2002

Facilitation of α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate receptor transmission in the suprachiasmatic nucleus by aniracetam enhances photic responses of the biological clock in rodents ⬇️

artículo científico publicado el 1 de mayo de 2003

Feeding and adrenal entrainment stimuli are both necessary for normal circadian oscillation of peripheral clocks in mice housed under different photoperiods

artículo científico publicado en 2014

Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120.

artículo científico publicado en 2015

Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: a reply to Fuller et al.

artículo científico publicado en 2009

Forced rather than voluntary exercise entrains peripheral clocks via a corticosterone/noradrenaline increase in PER2::LUC mice

artículo científico publicado en 2016

Glucagon and/or IGF-1 Production Regulates Resetting of the Liver Circadian Clock in Response to a Protein or Amino Acid-only Diet

artículo científico publicado en 2018

Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice

artículo científico publicado en 2007

Gut Microbiota-Derived Short Chain Fatty Acids Induce Circadian Clock Entrainment in Mouse Peripheral Tissue

artículo científico publicado en 2018

Housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes Per1, Per2, and Bmal1 in the amygdala and hippocampus of mice

artículo científico publicado en 2015

Impairment of Circadian Rhythms in Peripheral Clocks by Constant Light Is Partially Reversed by Scheduled Feeding or Exercise

artículo científico publicado en 2015

In vitro and in vivo Phase Changes of the Mouse Circadian Clock by Oxidative Stress

artículo científico publicado en 2016

In vivo monitoring of peripheral circadian clocks in the mouse

artículo científico publicado en 2012

Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock

artículo científico publicado en 2015

Inhibitory action of 5-HT1A agonist MKC-242 on triazolam-induced phase advances in hamster circadian activity rhythms

artículo científico publicado en 2005

Involvement of 5-HT₃ and 5-HT₄ receptors in the regulation of circadian clock gene expression in mouse small intestine

artículo científico publicado en 2014

Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock

artículo científico publicado en 2012

Leucine restores murine hepatic triglyceride accumulation induced by a low-protein diet by suppressing autophagy and excessive endoplasmic reticulum stress

artículo científico publicado en 2015

MAP kinase‐dependent induction of clock gene expression by α1‐adrenergic receptor activation ⬇️

artículo científico publicado el 8 de mayo de 2003

Meal frequency patterns determine the phase of mouse peripheral circadian clocks

artículo científico publicado en 2012

Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice

artículo científico publicado en 2003

Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse

artículo científico publicado en 2002

Modulation of rat behaviour by using a rat-like robot

artículo científico publicado en 2013

Motor discoordination in mutant mice lacking junctophilin type 3

scientific journal article

Multifactorial regulation of daily rhythms in expression of the metabolically responsive gene spot14 in the mouse liver

artículo científico publicado en 2007

Neural regulation of the hepatic circadian rhythm

artículo científico publicado en 2004

Night eating model shows time-specific depression-like behavior in the forced swimming test

artículo científico publicado en 2018

Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats

artículo científico publicado en 2005

ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle

artículo científico publicado en 2006

Optimization of dosing schedule of daily inhalant dexamethasone to minimize phase shifting of clock gene expression rhythm in the lungs of the asthma mouse model

artículo científico publicado en 2007

PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders

artículo científico publicado en 2007

PPARα is a potential therapeutic drug target of circadian rhythm sleep disorders

Phase shifts in circadian peripheral clocks caused by exercise are dependent on the feeding schedule in PER2::LUC mice

artículo científico publicado en 2016

Phase-delay in the light-dark cycle impairs clock gene expression and levels of serotonin, norepinephrine, and their metabolites in the mouse hippocampus and amygdala

artículo científico publicado en 2015

Phase-resetting response to (+)8-OH-DPAT, a serotonin 1A/7 receptor agonist, in the mouse in vivo

artículo científico publicado en 2004

Polyporus and Bupleuri radix effectively alter peripheral circadian clock phase acutely in male mice

artículo científico publicado en 2017

Positive association between physical activity and PER3 expression in older adults

artículo científico publicado en 2017

Potent Effects of Flavonoid Nobiletin on Amplitude, Period, and Phase of the Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblasts

artículo científico publicado en 2017

Potent synchronization of peripheral circadian clocks by glucocorticoid injections in PER2::LUC-Clock/Clock mice

artículo científico publicado en 2017

Prednisolone causes anxiety- and depression-like behaviors and altered expression of apoptotic genes in mice hippocampus

artículo científico publicado en 2009

Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice

artículo científico publicado en 2004

Refeeding after Fasting Elicits Insulin-Dependent Regulation of Per2 and Rev-erbα with Shifts in the Liver Clock ⬇️

artículo científico publicado el 1 de junio de 2011

Regulation of plasma histamine levels by the mast cell clock and its modulation by stress

artículo científico publicado en 2017

Restricted feeding induces daily expression of clock genes and Pai-1 mRNA in the heart of Clock mutant mice

artículo científico publicado en 2002

Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood

artículo científico publicado en 2009

Social jetlag and menstrual symptoms among female university students

artículo científico publicado en 2018

Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice

artículo científico publicado en 2009

Synthesis of a new [6]-gingerol analogue and its protective effect with respect to the development of metabolic syndrome in mice fed a high-fat diet

artículo científico publicado en 2011

The Role of Circadian Rhythms in Muscular and Osseous Physiology and Their Regulation by Nutrition and Exercise

scientific article published on 14 February 2017

The adjustment and manipulation of biological rhythms by light, nutrition, and abused drugs

artículo científico publicado en 2010

The circadian clock controls fluctuations of colonic cell proliferation during the light/dark cycle via feeding behavior in mice

artículo científico publicado en 2015

The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice.

artículo científico publicado en 2009

The mammalian circadian clock and its entrainment by stress and exercise

artículo científico publicado en 2017

The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women

artículo científico publicado en 2011

The role of Clock in the plasticity of circadian entrainment

artículo científico publicado en 2004

The role of GABAergic neuron on NMDA- and SP-induced phase delays in the suprachiasmatic nucleus neuronal activity rhythm in vitro

artículo científico publicado en 2009

Time of day and nutrients in feeding govern daily expression rhythms of the gene for sterol regulatory element-binding protein (SREBP)-1 in the mouse liver

artículo científico publicado en 2010

Time-dependent effect of glutamate on long-term potentiation in the suprachiasmatic nucleus of rats

artículo científico publicado en 2002

Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver

artículo científico publicado en 2010

Two distinct serotonin receptors co-mediate non-photic signals to the circadian clock

artículo científico publicado en 2013

Two-peaked Synchronization in Day/Night Expression Rhythms of the Fibrinogen Gene Cluster in the Mouse Liver ⬇️

artículo científico publicado el 14 de mayo de 2003

Warm water bath stimulates phase-shifts of the peripheral circadian clocks in PER2::LUCIFERASE mouse

artículo científico publicado en 2014

[Chrono-nutrition and chrono-exercise].

artículo científico publicado en 2013

l-Ornithine affects peripheral clock gene expression in mice

artículo científico publicado en 2016

γ-oryzanol ameliorates the acute stress induced by behavioral anxiety testing in mice

artículo científico publicado en 2018

Lista de obras de Shigenobu Shibata

2,2,2-Tribromoethanol Phase-Shifts the Circadian Rhythm of the Liver Clock in Per2::Luciferase Knockin Mice: Lack of Dependence on Anesthetic Activity ⬇️

A balanced diet is necessary for proper entrainment signals of the mouse liver clock

A low-protein diet eliminates the circadian rhythm of serum insulin and hepatic lipid metabolism in mice

A role of nociceptin in the entrainment mechanism of the biological clock

A single daily meal at the beginning of the active or inactive period inhibits food deprivation-induced fatty liver in mice

Abnormal tuning of the hepatic circadian metabolic rhythms in lung cancer

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

Adrenergic regulation of clock gene expression in mouse liver

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.

Age-related circadian disorganization caused by sympathetic dysfunction in peripheral clock regulation

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice

Anatomical cross-sectional area of the quadriceps femoris and sit-to-stand test score in middle-aged and elderly population: development of a predictive equation

Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

Association of body mass index-related single nucleotide polymorphisms with psychiatric disease and memory performance in a Japanese population

Attenuated Food Anticipatory Activity and Abnormal Circadian Locomotor Rhythms in Rgs16 Knockdown Mice ⬇️

Attenuating effect of clock mutation on triglyceride contents in the ICR mouse liver under a high-fat diet

Basic and applied science of chrononutrition ⬇️

Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1.

Ca2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin

Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver

Chrono-biology, chrono-pharmacology, and chrono-nutrition

Chrono-nutrition and n-3 polyunsaturated fatty acid

Circadian Clock mutation in dams disrupts nursing behavior and growth of pups

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function.

Circadian clock gene Period2 regulates a time-of-day–dependent variation in cutaneous anaphylactic reaction ⬇️

Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice

Circadian regulation of allergic reactions by the mast cell clock in mice

Circadian rhythms in the CNS and peripheral clock disorders: preface

Circadian rhythms in the CNS and peripheral clock disorders: the circadian clock and hyperlipidemia

Circadian rhythms of liver physiology and disease: experimental and clinical evidence

Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response

Combination of meal and exercise timing with a high-fat diet influences energy expenditure and obesity in mice

Constant light housing during nursing causes human DSPS (delayed sleep phase syndrome) behaviour in Clock-mutant mice

Controlling access time to a high-fat diet during the inactive period protects against obesity in mice.

Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.

Daily injection of insulin attenuated impairment of liver circadian clock oscillation in the streptozotocin-treated diabetic mouse

Dietary intake is associated with human chronotype as assessed by both morningness–eveningness score and preferred midpoint of sleep in young Japanese women ⬇️

Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation

Differential effect of lithium on the circadian oscillator in young and old hamsters

Differential roles of breakfast only (one meal per day) and a bigger breakfast with a small dinner (two meals per day) in mice fed a high-fat diet with regard to induced obesity and lipid metabolism ⬇️

Disruption of the suprachiasmatic nucleus blunts a time of day-dependent variation in systemic anaphylactic reaction in mice

Eating meals before wheel-running exercise attenuate high fat diet-driven obesity in mice under two meals per day schedule.

Effect of chronic ethanol exposure on the liver of Clock-mutant mice

Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei

Effect of quetiapine on Per1, Per2, and Bmal1 clock gene expression in the mouse amygdala and hippocampus

Effects of Meal Timing on Postprandial Glucose Metabolism and Blood Metabolites in Healthy Adults

Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice

Effects of medial hypothalamic lesions on feeding-induced entrainment of locomotor activity and liver Per2 expression in Per2::luc mice

Entrainment of mouse peripheral circadian clocks to <24 h feeding/fasting cycles under 24 h light/dark conditions

Entrainment of the mouse circadian clock by sub-acute physical and psychological stress

Entrainment of the mouse circadian clock: Effects of stress, exercise, and nutrition

Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis

Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice

Facilitation of α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate receptor transmission in the suprachiasmatic nucleus by aniracetam enhances photic responses of the biological clock in rodents ⬇️

Feeding and adrenal entrainment stimuli are both necessary for normal circadian oscillation of peripheral clocks in mice housed under different photoperiods

Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120.

Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: a reply to Fuller et al.

Forced rather than voluntary exercise entrains peripheral clocks via a corticosterone/noradrenaline increase in PER2::LUC mice

Glucagon and/or IGF-1 Production Regulates Resetting of the Liver Circadian Clock in Response to a Protein or Amino Acid-only Diet

Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice

Gut Microbiota-Derived Short Chain Fatty Acids Induce Circadian Clock Entrainment in Mouse Peripheral Tissue

Housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes Per1, Per2, and Bmal1 in the amygdala and hippocampus of mice

Impairment of Circadian Rhythms in Peripheral Clocks by Constant Light Is Partially Reversed by Scheduled Feeding or Exercise

In vitro and in vivo Phase Changes of the Mouse Circadian Clock by Oxidative Stress

In vivo monitoring of peripheral circadian clocks in the mouse

Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock

Inhibitory action of 5-HT1A agonist MKC-242 on triazolam-induced phase advances in hamster circadian activity rhythms

Involvement of 5-HT₃ and 5-HT₄ receptors in the regulation of circadian clock gene expression in mouse small intestine

Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock

Leucine restores murine hepatic triglyceride accumulation induced by a low-protein diet by suppressing autophagy and excessive endoplasmic reticulum stress

MAP kinase‐dependent induction of clock gene expression by α1‐adrenergic receptor activation ⬇️

Meal frequency patterns determine the phase of mouse peripheral circadian clocks

Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmatic nucleus in mice

Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse

Modulation of rat behaviour by using a rat-like robot

Motor discoordination in mutant mice lacking junctophilin type 3