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Lista de obras de John W. Semple

A comprehensive study of ovine haemostasis to assess suitability to model human coagulation.

artículo científico publicado en 2014

A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP).

artículo científico publicado en 2017

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy

artículo científico publicado en 2009

A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells

artículo científico publicado en 2008

A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy

artículo científico publicado en 2005

A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?

artículo científico publicado en 2006

About the mechanism of action of WinRho SDF

artículo científico publicado en 2007

Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets

artículo científico publicado en 2017

Acute Lung Injury Causes Asynchronous Alveolar Ventilation That Can Be Corrected by Individual Sighs

artículo científico publicado en 2015

Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2.

artículo científico publicado en 2016

Allogeneic platelet transfusions prevent murine T-cell-mediated immune thrombocytopenia

artículo científico publicado en 2013

An update on the pathophysiology of immune thrombocytopenia

scientific article published on 29 August 2020

Anti-D (WinRho SD) treatment of children with chronic autoimmune thrombocytopenic purpura stimulates transient cytokine/chemokine production

artículo científico publicado en 2002

Anti-D initially stimulates an Fc-dependent leukocyte oxidative burst and subsequently suppresses erythrophagocytosis via interleukin-1 receptor antagonist

artículo científico publicado en 2003

Antigen binding and processing by B-cell antigen-presenting cells: influence on T- and B-cell activation

artículo científico publicado en 1989

Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia

artículo científico publicado en 2018

Autoimmune pathogenesis and autoimmune hemolytic anemia

artículo científico publicado en 2005

Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation

artículo científico publicado en 2020

Bregging rights in ITP.

artículo científico publicado en 2012

C-reactive protein boosts antibody-mediated platelet destruction

artículo científico publicado en 2015

C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury

artículo científico publicado en 2015

CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell-mediated immune thrombocytopenia

artículo científico publicado en 2015

Cellular immune dysfunction in immune thrombocytopenia (ITP).

artículo científico publicado en 2013

Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update

artículo científico publicado en 2003

Cellular immune mechanisms in chronic autoimmune thrombocytopenic purpura (ATP)

artículo científico publicado el 1 de enero de 1992

Characterization of platelet-reactive antibodies in children with varicella-associated acute immune thrombocytopenic purpura (ITP).

artículo científico publicado en 1996

Comparison of platelet immunity in patients with SLE and with ITP.

artículo científico publicado en 2000

Current problems and future directions of transfusion‐induced alloimmunization: summary of an NHLBI working group

artículo científico publicado el 20 de enero de 2011

DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis.

artículo científico publicado en 2016

Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity

artículo científico publicado en 1996

Downregulation of the anti-HLA alloimmune response by variable region-reactive (anti-idiotypic) antibodies in leukemic patients transfused with platelet concentrates

artículo científico publicado en 1993

Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury.

artículo científico publicado en 2016

Epitope specificity and isotype of monoclonal anti-D antibodies dictate their ability to inhibit phagocytosis of opsonized platelets

artículo científico publicado en 2007

Evaluation of Platelet Responses in Transfusion-Related Acute Lung Injury (TRALI)

scientific article published on 16 September 2020

Evaluation of platelet gel characteristics using thrombin produced by the thrombin processing device: a comparative study

artículo científico publicado en 2008

Extreme leukoreduction of major histocompatibility complex class II positive B cells enhances allogeneic platelet immunity

artículo científico publicado en 1999

FcγRI and FcγRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia

artículo científico publicado en 2020

Flow cytometric analysis of platelets from childrenwith the Wiskott‐Aldrich syndrome reveals defects in platelet development, activation and structure

artículo científico publicado el 1 de junio de 1997

Flow cytometric evaluation of platelet activation in blood collected into EDTA vs. Diatube-H, a sodium citrate solution supplemented with theophylline, adenosine, and dipyridamole

scientific article published on 01 September 1995

Flow cytometric parameters for characterizing platelet activation by measuring P-selectin (CD62) expression: theoretical consideration and evaluation in thrombin-treated platelet populations

artículo científico publicado en 2000

Gamma-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response.

artículo científico publicado en 2002

Gastrointestinal microbiota contributes to the development of murine transfusion-related acute lung injury

article

HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management

artículo científico publicado en 2012

ITP has elevated BAFF expression

artículo científico publicado en 2009

ITP three R's: regulation, routing, rituximab

scientific article published on 01 August 2008

ITP: a new regulatory issue!

artículo científico publicado en 2007

IVIG induces dose-dependent amelioration of ITP in rodent models

artículo científico publicado en 2003

IVIg inhibits reticuloendothelial system function and ameliorates murine passive-immune thrombocytopenia independent of anti-idiotype reactivity.

artículo científico publicado en 2001

IgG antiplatelet immunity is dependent on an early innate natural killer cell-derived interferon-gamma response that is regulated by CD8+ T cells

artículo científico publicado en 2003

Immune responsiveness against allogeneic platelet transfusions is determined by the recipient's major histocompatibility complex class II phenotype

artículo científico publicado en 2004

Immunobiology of T helper cells and antigen-presenting cells in autoimmune thrombocytopenic purpura (ITP).

artículo científico publicado en 1998

In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies

artículo científico publicado en 2009

Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia

artículo científico publicado el 15 de noviembre de 1991

Indirect allorecognition of platelets by T helper cells during platelet transfusions correlates with anti-major histocompatibility complex antibody and cytotoxic T lymphocyte formation

artículo científico publicado el 15 de julio de 1995

Induction of a secondary human anti-HLA alloimmune response in severe combined immunodeficient mice engrafted with human lymphocytes

artículo científico publicado en 1997

Infections, antigen-presenting cells, T cells, and immune tolerance: their role in the pathogenesis of immune thrombocytopenia

artículo científico publicado en 2009

Influence of antigen processing on immune responsiveness

artículo científico publicado en 1988

Inhibition of xenogeneic GVHD by PEN110 treatment of donor human PBMNCs

artículo científico publicado en 2004

Innate and adaptive immunity in immune thrombocytopenia

artículo científico publicado en 2013

Intravenous immunoglobulin and anti-D in idiopathic thrombocytopenic purpura (ITP): mechanisms of action

artículo científico publicado en 1998

Intravenous immunoglobulin inhibits anti-glycoprotein IIb-induced platelet apoptosis in a murine model of immune thrombocytopenia

artículo científico publicado en 2006

Intravenous immunoglobulin prevents murine antibody-mediated acute lung injury at the level of neutrophil reactive oxygen species (ROS) production

artículo científico publicado en 2012

Intravenous immunoglobulin treatment of spleen cells from patients with immune thrombocytopenia significantly increases the percentage of myeloid-derived suppressor cells

artículo científico publicado en 2017

Leukoreduction just doesn't "take away" immunogenic leukcocytes, it creates an immunosuppressive leukocyte dose.

artículo científico publicado en 2002

Low levels of interleukin-10 in patients with transfusion-related acute lung injury

artículo científico publicado en 2017

Management of immune thrombocytopenic purpura in children: potential role of novel agents

artículo científico publicado en 2011

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets

artículo científico publicado en 2017

Mechanisms and therapeutic prospects of thrombopoietin receptor agonists

artículo científico

Megakaryocytes listen for their progeny's progeny during inflammation

artículo científico publicado en 2020

Microparticles as biomarkers of lung disease: enumeration in biological fluids using lipid bilayer microspheres

artículo científico publicado en 2016

Move over Tregs, MDSCs are here

artículo científico publicado en 2016

Moving target PF4 directs HIT responses

article

Natural killer cell numbers and activity in patients with chronic autoimmune thrombocytopenic purpura

artículo científico publicado en 1994

Naturally processed heterodimeric disulfide-linked insulin peptides bind to major histocompatibility class II molecules on thymic epithelial cells

artículo científico publicado en 1994

New Emerging Developments of Platelets in Transfusion Medicine

scientific article published on 07 October 2020

Nouvelle cuisine: platelets served with inflammation

artículo científico publicado en 2015

Osteopontin mediates murine transfusion-related acute lung injury via stimulation of pulmonary neutrophil accumulation

scientific article published on 10 May 2019

Pathogenesis of immune thrombocytopenia

artículo científico publicado en 2014

Pathogenesis and Therapeutic Mechanisms in  Immune Thrombocytopenia (ITP)

artículo científico publicado en 2017

Pathogenic T-cell responses in patients with autoimmune thrombocytopenic purpura

artículo científico publicado en 2003

Pathways of processing of insulin by antigen-presenting cells

artículo científico publicado en 1988

Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI)

artículo científico publicado en 2014

Plasma-derived biological medicines used to promote haemostasis

artículo científico publicado en 2008

Platelet Extracellular Vesicles mediate Transfusion-related Acute Lung Injury by imbalancing the Sphingolipid Rheostat

artículo científico publicado en 2020

Platelet GPIb-IX has suppressive effects on septic inflammation

artículo científico publicado en 2014

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo

artículo científico publicado en 2005

Platelet and immune responses to oral cyclic dexamethasone therapy in childhood chronic immune thrombocytopenic purpura

artículo científico publicado en 1997

Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells

artículo científico publicado en 2007

Platelet antigen-induced regulation in ITP

artículo científico publicado en 2009

Platelet immunobiology: platelets as prey and predator

scholarly article by R. Kapur & John W. Semple published 3 October 2017 in ISBT Science Series

Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets

artículo científico publicado en 2007

Platelet-surface glycoproteins in healthy and preeclamptic mothers and their newborn infants

artículo científico publicado en 1996

Platelets and innate immunity

artículo científico publicado en 2009

Platelets and the immune continuum

artículo científico publicado el 1 de abril de 2011

Platelets as immune-sensing cells

article

Platelets deliver small packages of genetic function

artículo científico publicado en 2013

Platelets give us many messages

artículo científico publicado el 1 de octubre de 2003

Platelets play a direct role in sepsis-associated endothelial cell death

artículo científico publicado en 2008

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

artículo científico publicado en 2014

Preanalytical requirements for flow cytometric evaluation of platelet activation: choice of anticoagulant

artículo científico publicado en 1999

Processed platelet HPA1a peptides au naturel

artículo científico publicado en 2009

Processing and presentation of insulin. II. Evidence for intracellular, plasma membrane-associated and extracellular degradation of human insulin by antigen-presenting B cells

artículo científico publicado en 1989

Processing and presentation of insulin. III. Insulin degrading enzyme: a neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells

artículo científico publicado el 1 de octubre de 1992

Quality of thrombin produced from the patient's own plasma using the TPD, a new Thrombin-processing Device.

artículo científico publicado en 2005

Quantification of platelet activation status by analyzing P-selectin expression

artículo científico publicado en 2000

Rapid separation of CD4+ and CD19+ lymphocyte populations from human peripheral blood by a magnetic activated cell sorter (MACS)

artículo científico publicado en 1993

Recent progress in understanding the pathogenesis of immune thrombocytopenia

artículo científico publicado en 2010

Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury

scientific article published on 08 July 2010

Recipient antigen-processing pathways of allogeneic platelet antigens: essential mediators of immunity

artículo científico publicado en 2002

Recipient humoral immunity against leukoreduced allogeneic platelets is suppressed by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase

scientific article published on 01 October 1996

Single nucleotide polymorphism (SNP) analysis demonstrates a significant association of tumour necrosis factor-alpha (TNFA) with primary immune thrombocytopenia among Caucasian adults

artículo científico publicado en 2011

Splenic lymphocyte subtypes in immune thrombocytopenia: increased presence of a subtype of B-regulatory cells

scientific article published on 24 June 2015

Sulfated beef insulin treatment elicits CD8+ T cells that may abrogate immunologic insulin resistance in type I diabetes

artículo científico publicado en 1989

Suppressed natural killer cell activity in patients with chronic autoimmune thrombocytopenic purpura

artículo científico publicado el 1 de agosto de 1991

T cell and cytokine abnormalities in patients with autoimmune thrombocytopenic purpura

artículo científico publicado el 1 de junio de 2003

T granules in human platelets function in TLR9 organization and signaling

artículo científico publicado en 2012

T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10.

artículo científico publicado en 2017

Targeting Transfusion-Related Acute Lung Injury: The Journey From Basic Science to Novel Therapies.

artículo científico publicado en 2018

The Immune Nature of Platelets Revisited

artículo científico publicado en 2020

The Pathogenic Involvement of Neutrophils in Acute Respiratory Distress Syndrome and Transfusion-Related Acute Lung Injury

artículo científico publicado en 2018

The Role of Complement in Transfusion-Related Acute Lung Injury

scientific article published on 18 October 2019

The Ultimate Murine Model of Immune Thrombocytopaenia

scientific article published on 06 February 2019

The cellular immunology associated with autoimmune thrombocytopenic purpura: an update.

artículo científico publicado en 1998

The contribution of recipient platelets in TRALI: has the jury reached a verdict?

scientific article published on 01 May 2020

The immunopathogenesis of immune thrombocytopenia: T cells still take center-stage

artículo científico publicado en 2012

The nonhemostatic immune functions of platelets.

artículo científico publicado en 2016

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia

artículo científico publicado en 2016

The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation

artículo científico publicado en 2017

Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP)

scientific article published on 30 May 2019

Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia

artículo científico publicado en 2012

Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia

artículo científico publicado en 2016

Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model.

artículo científico publicado en 2010

Transfusion-associated circulatory overload (TACO): Time to shed light on the pathophysiology

Transfusion-associated circulatory overload and transfusion-related acute lung injury

scientific article published on 26 February 2019

Transfusion-related Acute Lung Injury in the Perioperative Patient

scientific article published on 01 September 2019

Transfusion-related immunomodulation by platelets is dependent on their expression of MHC Class I molecules and is independent of white cells

artículo científico publicado en 2008

Treating murine inflammatory diseases with an anti-erythrocyte antibody

artículo científico publicado en 2019

Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens

artículo científico publicado en 2000

Update on the pathophysiology of transfusion-related acute lung injury

scientific article published on 29 August 2020