Lista de obras - Dalia Barsyte-Lovejoy - Dominio Público Uruguay

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

artículo científico publicado en 2014

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

artículo científico publicado en 2015

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

artículo científico publicado en 2019

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

artículo científico publicado en 2011

A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9a.

artículo científico publicado en 2014

A combinatorial anticancer drug screen identifies off-target effects of epigenetic chemical probes

A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)

artículo científico publicado en 2015

AT-21INTEGRATED (EPI)GENOMIC ANALYSES IDENTIFY SUB-GROUP SPECIFIC THERAPEUTIC TARGETS IN CNS RHABDOID TUMORS.

artículo científico publicado en 2016

An Integrative Proteomic Approach Identifies Novel Cellular SMYD2 Substrates

artículo científico

An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1

artículo científico publicado en 2013

Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression

artículo científico publicado en 2003

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

artículo científico publicado en 2012

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

scientific article published on 26 May 2020

C-terminal processing of the teneurin proteins: independent actions of a teneurin C-terminal associated peptide in hippocampal cells

scientific journal article

CUL7 is a novel antiapoptotic oncogene

artículo científico publicado en 2007

Cancer therapeutics: targeting the dark side of Myc.

artículo científico publicado en 2005

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

artículo científico publicado en 2012

Characterization of a corticotropin-releasing factor (CRF)/diuretic hormone-like peptide from tunicates: insight into the origins of the vertebrate CRF family.

artículo científico publicado en 2009

Cloning and characterization of teneurin C-terminus associated peptide (TCAP)-3 from the hypothalamus of an adult rainbow trout (Oncorhynchus mykiss).

artículo científico publicado en 2004

Control of the hippo pathway by Set7-dependent methylation of Yap.

artículo científico publicado en 2013

Discovery of a Dual PRMT5-PRMT7 Inhibitor

artículo científico publicado en 2015

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor

artículo científico publicado en 2016

Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening

artículo científico publicado en 2016

Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.

artículo científico publicado en 2016

Discovery of a chemical probe for PRDM9

scientific article published on 17 December 2019

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

artículo científico publicado en 2013

Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.

artículo científico publicado en 2013

ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motif

artículo científico publicado en 2004

Erratum: A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

article

Erratum: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

artículo científico publicado en 2013

Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

scholarly article by Florian Grebien et al published October 2015 in Nature Chemical Biology

Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

artículo científico publicado en 2017

Evolution of complementary peptide systems: teneurin C-terminal-associated peptides and corticotropin-releasing factor superfamilies

artículo científico publicado en 2009

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

scientific article published on 08 July 2019

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

artículo científico publicado en 2015

Histone recognition and large-scale structural analysis of the human bromodomain family

artículo científico publicado en 2012

Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells

artículo científico publicado en 2005

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

artículo científico publicado en 2016

Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells

artículo científico publicado en 2007

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.

artículo científico publicado en 2015

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin

artículo científico publicado en 2015

Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines

artículo científico publicado en 2011

PRMT5 inhibition disrupts splicing and stemness in glioblastoma

artículo científico publicado en 2021

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

artículo científico publicado en 2022

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

preprint

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

artículo científico publicado en 2020

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

artículo científico publicado en 2015

Promoter-binding and repression of PDGFRB by c-Myc are separable activities

artículo científico publicado en 2004

Protein arginine methylation: from enigmatic functions to therapeutic targeting

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

artículo científico publicado en 2013

Specificity determinants in MAPK signaling to transcription factors

artículo científico publicado en 2002

Systems approaches to genomic and epigenetic inter-regulation of peptide hormones in stress and reproduction

artículo científico

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma.

artículo científico publicado en 2018

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

scientific article published on 29 March 2019

Targeting human SET1/MLL family of proteins

artículo científico publicado en 2017

Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion

Teneurin carboxy (C)-terminal associated peptide-1 inhibits alkalosis-associated necrotic neuronal death by stimulating superoxide dismutase and catalase activity in immortalized mouse hypothalamic cells

artículo científico publicado en 2007

Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity.

artículo científico publicado en 2005

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

artículo científico publicado en 2017

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

artículo científico publicado en 2017

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis

artículo científico publicado en 2006

c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism

artículo científico publicado en 2004

Lista de obras de Dalia Barsyte-Lovejoy

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9a.

A combinatorial anticancer drug screen identifies off-target effects of epigenetic chemical probes

A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)

AT-21INTEGRATED (EPI)GENOMIC ANALYSES IDENTIFY SUB-GROUP SPECIFIC THERAPEUTIC TARGETS IN CNS RHABDOID TUMORS.

An Integrative Proteomic Approach Identifies Novel Cellular SMYD2 Substrates

An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1

Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

C-terminal processing of the teneurin proteins: independent actions of a teneurin C-terminal associated peptide in hippocampal cells

CUL7 is a novel antiapoptotic oncogene

Cancer therapeutics: targeting the dark side of Myc.

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Characterization of a corticotropin-releasing factor (CRF)/diuretic hormone-like peptide from tunicates: insight into the origins of the vertebrate CRF family.

Cloning and characterization of teneurin C-terminus associated peptide (TCAP)-3 from the hypothalamus of an adult rainbow trout (Oncorhynchus mykiss).

Control of the hippo pathway by Set7-dependent methylation of Yap.

Discovery of a Dual PRMT5-PRMT7 Inhibitor

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor

Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening

Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.

Discovery of a chemical probe for PRDM9

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.

ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motif

Erratum: A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Erratum: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

Evolution of complementary peptide systems: teneurin C-terminal-associated peptides and corticotropin-releasing factor superfamilies

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Histone recognition and large-scale structural analysis of the human bromodomain family

Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin

Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines

PRMT5 inhibition disrupts splicing and stemness in glioblastoma

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Promoter-binding and repression of PDGFRB by c-Myc are separable activities

Protein arginine methylation: from enigmatic functions to therapeutic targeting

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

Specificity determinants in MAPK signaling to transcription factors

Systems approaches to genomic and epigenetic inter-regulation of peptide hormones in stress and reproduction

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma.

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

Targeting human SET1/MLL family of proteins

Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion

Teneurin carboxy (C)-terminal associated peptide-1 inhibits alkalosis-associated necrotic neuronal death by stimulating superoxide dismutase and catalase activity in immortalized mouse hypothalamic cells

Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity.

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis

c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism