Lista de obras -

A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter

artículo científico publicado en 2009

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

artículo científico publicado en 2013

A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals candidate regulatory elements for genes coordinating epididymal function

artículo científico publicado en 2013

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function

artículo científico publicado en 2012

Abstract B44: Chromatin structure impacts androgen receptor transcriptional specificity in prostate cancer cell lines

Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.

artículo científico

Allele-specific and heritable chromatin signatures in humans

artículo científico publicado en 2010

An encyclopedia of mouse DNA elements (Mouse ENCODE).

artículo científico publicado en 2012

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression

artículo científico publicado en 2010

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

artículo científico publicado en 2017

Case conferencing for palliative care patients - a survey of South Australian general practitioners

artículo científico publicado en 2017

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

artículo científico publicado en 2011

Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma

artículo científico publicado en 2014

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

artículo científico publicado en 2012

Combined reflectance spectroscopy and stochastic modeling approach for noninvasive hemoglobin determination via palpebral conjunctiva

artículo científico publicado en 2014

Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee

artículo científico publicado en 2018

Correction: Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

artículo científico publicado en 2015

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

artículo científico publicado en 2016

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

artículo científico publicado en 2017

DNA methylation and differentiation: HOX genes in muscle cells ⬇️

artículo científico publicado el 2 de agosto de 2013

DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays

artículo científico publicado en 2006

DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types

artículo científico publicado en 2013

DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells

artículo científico publicado en 2010

DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2

artículo científico publicado en 2009

DNase I sensitivity QTLs are a major determinant of human expression variation

artículo científico publicado en 2012

Defining functional DNA elements in the human genome

artículo científico publicado en 2014

Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription

artículo científico publicado en 2014

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

artículo científico publicado en 2015

Digital imaging, spectroscopy, and liquid crystals in a hand-held, non-invasive device to determine hemoglobin concentration

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

artículo científico publicado en 2016

Dissecting the regulatory architecture of gene expression QTLs

artículo científico publicado en 2012

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

artículo científico publicado en 2007

Dynamic DNA methylation across diverse human cell lines and tissues

artículo científico publicado en 2013

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

artículo científico publicado en 2011

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

artículo científico publicado en 2012

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage

artículo científico publicado en 2010

Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection

artículo científico publicado en 2014

Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection

artículo científico publicado en 2012

F-Seq: a feature density estimator for high-throughput sequence tags

artículo científico publicado en 2008

Gene expression during normal and FSHD myogenesis ⬇️

artículo científico publicado el 27 de septiembre de 2011

Genetic and epigenetic determinants of inter-individual variability in responses to toxicants

article

Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus

artículo científico publicado en 2015

Genome accessibility is widely preserved and locally modulated during mitosis

artículo científico publicado en 2014

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

artículo científico publicado en 2006

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

artículo científico publicado en 2018

Genome-wide identification of regulatory elements in Sertoli cells

artículo científico publicado en 2017

Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)

artículo científico publicado en 2005

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

artículo científico publicado en 2015

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

artículo científico publicado en 2015

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

artículo científico publicado en 2009

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

artículo científico publicado en 2010

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites ⬇️

artículo científico publicado el 28 de mayo de 2012

HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells

artículo científico publicado en 2016

Heritable individual-specific and allele-specific chromatin signatures in humans

artículo científico publicado en 2010

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

artículo científico publicado en 2011

High-resolution mapping and characterization of open chromatin across the genome

artículo científico publicado en 2008

High-resolution mapping of open chromatin in the rice genome

artículo científico publicado en 2011

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

artículo científico publicado en 2015

Histone modifications at human enhancers reflect global cell-type-specific gene expression

artículo científico publicado en 2009

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

article published in 2018

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

artículo científico publicado en 2007

Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome

artículo científico publicado en 2007

Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites

artículo científico publicado en 2004

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

artículo científico publicado en 2017

Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation

artículo científico publicado en 2015

Interferon regulatory factors are transcriptional regulators of adipogenesis

artículo científico publicado en 2008

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

artículo científico publicado en 2009

Major mental illness and violence history as predictors of institutional misconduct and recidivism: main and interaction effects

artículo científico

Mapping nucleosome positions using DNase-seq

artículo científico publicado en 2016

Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip).

artículo científico publicado en 2009

Mesoscale Three Dimensional Lattices Formed in Polymer Dispersed Liquid Crystals: A Diamond-Like Face Centered Cubic

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

artículo científico publicado en 2014

Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha

artículo científico publicado en 2017

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

artículo científico publicado en 2010

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes

artículo científico publicado en 2012

Non-invasive determination of hemoglobin by digital photography of palpebral conjunctiva

artículo científico publicado en 2007

Noninvasive optical, electrical, and acoustic methods of total hemoglobin determination

scientific article published on 10 December 2007

Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine

artículo científico publicado en 2014

Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

artículo científico publicado en 2011

Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function

artículo científico publicado en 2014

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

artículo científico publicado en 2013

Photonics-based in vivo total hemoglobin monitoring and clinical relevance

artículo científico publicado en 2009

Point-of-care noninvasive hemoglobin determination using fiber optic reflectance spectroscopy

artículo científico publicado en 2007

Predicting cell-type-specific gene expression from regions of open chromatin

artículo científico publicado en 2012

Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

artículo científico publicado en 2014

Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9.

artículo científico publicado en 2017

Reflectance spectrometry of normal and bruised human skins: experiments and modeling

artículo científico publicado el 19 de enero de 2012

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

artículo científico publicado en 2015

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease

artículo científico publicado en 2014

Retroviral DNA integration: viral and cellular determinants of target-site selection

artículo científico publicado en 2006

Roles of the state asthma program in implementing multicomponent, school-based asthma interventions

artículo científico publicado en 2013

Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing

artículo científico publicado en 2018

Site-specific silencing of regulatory elements as a mechanism of X inactivation

artículo científico publicado en 2012

Statistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays

artículo científico publicado en 2006

Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation

artículo científico publicado en 2016

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

artículo científico publicado en 2013

The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes ⬇️

artículo científico publicado el 16 de julio de 2012

The PsychENCODE project

artículo científico publicado en 2015

The accessible chromatin landscape of the human genome

artículo científico publicado en 2012

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

scientific article published on 29 June 2016

Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription

artículo científico publicado en 2018

Tolerance of the skull to blunt ballistic temporo-parietal impact

artículo científico publicado en 2009

Using Positive Organizational Scholarship in Healthcare and Video Reflexive Ethnography to Examine Positive Deviance to New Public Management in Healthcare

artículo científico publicado en 2018

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice

artículo científico publicado en 2017

Lista de obras de

A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals candidate regulatory elements for genes coordinating epididymal function

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function

Abstract B44: Chromatin structure impacts androgen receptor transcriptional specificity in prostate cancer cell lines

Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.

Allele-specific and heritable chromatin signatures in humans

An encyclopedia of mouse DNA elements (Mouse ENCODE).

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Case conferencing for palliative care patients - a survey of South Australian general practitioners

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

Combined reflectance spectroscopy and stochastic modeling approach for noninvasive hemoglobin determination via palpebral conjunctiva

Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee

Correction: Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

DNA methylation and differentiation: HOX genes in muscle cells ⬇️

DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays

DNase-seq predicts regions of rotational nucleosome stability across diverse human cell types

DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells

DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2

DNase I sensitivity QTLs are a major determinant of human expression variation

Defining functional DNA elements in the human genome

Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Digital imaging, spectroscopy, and liquid crystals in a hand-held, non-invasive device to determine hemoglobin concentration

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

Dissecting the regulatory architecture of gene expression QTLs

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Dynamic DNA methylation across diverse human cell lines and tissues

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage

Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection

Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection

F-Seq: a feature density estimator for high-throughput sequence tags

Gene expression during normal and FSHD myogenesis ⬇️

Genetic and epigenetic determinants of inter-individual variability in responses to toxicants

Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus

Genome accessibility is widely preserved and locally modulated during mitosis

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Genome-wide identification of regulatory elements in Sertoli cells

Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites ⬇️

HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells

Heritable individual-specific and allele-specific chromatin signatures in humans

High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

High-resolution mapping and characterization of open chromatin across the genome

High-resolution mapping of open chromatin in the rice genome

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

Histone modifications at human enhancers reflect global cell-type-specific gene expression

Human cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome

Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation

Interferon regulatory factors are transcriptional regulators of adipogenesis

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

Major mental illness and violence history as predictors of institutional misconduct and recidivism: main and interaction effects

Mapping nucleosome positions using DNase-seq

Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip).

Mesoscale Three Dimensional Lattices Formed in Polymer Dispersed Liquid Crystals: A Diamond-Like Face Centered Cubic

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes

Non-invasive determination of hemoglobin by digital photography of palpebral conjunctiva