Lista de obras - David Sattelle - Dominio Público Uruguay

2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

artículo científico publicado en 2018

A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function

artículo científico publicado en 2010

A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds

artículo científico publicado en 2010

A quasi-elastic laser light scattering study of tubulin and microtubule protein from bovine brain

artículo científico publicado en 1982

A7DB: a relational database for mutational, physiological and pharmacological data related to the alpha7 nicotinic acetylcholine receptor

artículo científico publicado en 2005

Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes

artículo científico publicado en 2014

Actions of snake neurotoxins on an insect nicotinic cholinergic synapse

artículo científico publicado en 2007

Alzheimer's disease: insights from Drosophila melanogaster models

artículo científico publicado en 2009

An L319F mutation in transmembrane region 3 (TM3) selectively reduces sensitivity to okaramine B of the Bombyx mori l-glutamate-gated chloride channel.

artículo científico publicado en 2017

An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro

artículo científico publicado en 2014

Anthelmintic drug discovery: target identification, screening methods and the role of open science

artículo científico publicado en 2020

Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance

artículo científico publicado en 2021

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics

artículo científico publicado en 2014

Caenorhabditis elegans in the study of SMN-interacting proteins: a role for SMI-1, an orthologue of human Gemin2 and the identification of novel components of the SMN complex

artículo científico publicado en 2006

Chemistry-to-gene screens in Caenorhabditis elegans

artículo científico publicado en 2005

Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions

artículo científico publicado en 2020

Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin

artículo científico publicado en 2008

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo

artículo científico publicado en 2017

Effects of mutations of a glutamine residue in loop D of the alpha7 nicotinic acetylcholine receptor on agonist profiles for neonicotinoid insecticides and related ligands

artículo científico publicado en 2002

Exon 3 splicing and mutagenesis identify residues influencing cell surface density of heterologously expressed silkworm (Bombyx mori) glutamate-gated chloride channels

artículo científico publicado en 2014

Exploring the pharmacological properties of insect nicotinic acetylcholine receptors

artículo científico publicado en 2006

Fast, automated measurement of nematode swimming (thrashing) without morphometry

artículo científico publicado en 2009

Functional and evolutionary insights from the genomes of three parasitoid Nasonia species

artículo científico publicado en 2010

Functional characterisation of a nicotinic acetylcholine receptor α subunit from the brown dog tick, Rhipicephalus sanguineus

artículo científico publicado en 2013

Functional genomics of ionotropic acetylcholine receptors in Caenorhabditis elegans and Drosophila melanogaster

artículo científico publicado en 2002

Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans

artículo científico publicado en 2004

Gene silencing of selected calcium-signalling molecules in a Drosophila cell line using double-stranded RNA interference

artículo científico publicado en 2004

Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment

artículo científico publicado en 2014

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

artículo científico publicado en 2016

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans

artículo científico publicado en 2011

Insect nicotinic acetylcholine receptor gene families: from genetic model organism to vector, pest and beneficial species.

artículo científico publicado en 2007

Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics

artículo científico publicado en 2011

Ion channels: molecular targets of neuroactive insecticides

artículo científico publicado en 2005

Is spinal muscular atrophy the result of defects in motor neuron processes?

artículo científico publicado en 2005

Laser-light scattering diffusion measurements on brain microtubule protein from dogfish (Squalus acanthus) and beef ⬇️

artículo científico publicado el 1 de diciembre de 1981

Loops D, E and G in the Drosophila Dα1 subunit contribute to high neonicotinoid sensitivity of Dα1-chicken β2 nicotinic acetylcholine receptor.

artículo científico publicado en 2017

Mechanisms of action, resistance and toxicity of insecticides targeting GABA receptors.

artículo científico publicado en 2017

Modes of action, resistance and toxicity of insecticides targeting nicotinic acetylcholine receptors.

artículo científico publicado en 2017

Motility of bovine spermatozoa studied by laser light scattering

artículo científico publicado en 1985

Neonicotinoids show selective and diverse actions on their nicotinic receptor targets: electrophysiology, molecular biology, and receptor modeling studies.

artículo científico publicado en 2005

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.

artículo científico publicado en 2009

Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics.

artículo científico publicado en 2007

Novel animal-health drug targets from ligand-gated chloride channels.

artículo científico publicado en 2002

Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons.

artículo científico publicado en 2010

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

artículo científico publicado en 2004

Spectrometer for laser-light scattering measurements of macromolecular and subcellular particle motions

artículo científico publicado en 1982

Strategies for automated analysis of C. elegans locomotion

scientific article published on 08 August 2008

Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms

artículo científico publicado en 2005

Studies on an acetylcholine binding protein identify a basic residue in loop G on the β1 strand as a new structural determinant of neonicotinoid actions

artículo científico publicado en 2014

Subtype-specific actions of beta-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4) expressed in Xenopus laevis oocytes

artículo científico publicado en 2005

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.

artículo científico publicado en 2014

The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum

artículo científico publicado en 2007

The genome of the model beetle and pest Tribolium castaneum

artículo científico publicado en 2008

The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera.

artículo científico publicado en 2006

The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature

artículo científico publicado en 2007

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits

artículo científico publicado en 2009

Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster

artículo científico publicado en 2003

Tick Genome Assembled: New Opportunities for Research on Tick-Host-Pathogen Interactions

artículo científico publicado en 2016

Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery?

artículo científico publicado en 2020

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.

artículo científico publicado en 2012

Lista de obras de David Sattelle

2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function

A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds

A quasi-elastic laser light scattering study of tubulin and microtubule protein from bovine brain

A7DB: a relational database for mutational, physiological and pharmacological data related to the alpha7 nicotinic acetylcholine receptor

Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes

Actions of snake neurotoxins on an insect nicotinic cholinergic synapse

Alzheimer's disease: insights from Drosophila melanogaster models

An L319F mutation in transmembrane region 3 (TM3) selectively reduces sensitivity to okaramine B of the Bombyx mori l-glutamate-gated chloride channel.

An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro

Anthelmintic drug discovery: target identification, screening methods and the role of open science

Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics

Caenorhabditis elegans in the study of SMN-interacting proteins: a role for SMI-1, an orthologue of human Gemin2 and the identification of novel components of the SMN complex

Chemistry-to-gene screens in Caenorhabditis elegans

Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions

Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo

Effects of mutations of a glutamine residue in loop D of the alpha7 nicotinic acetylcholine receptor on agonist profiles for neonicotinoid insecticides and related ligands

Exon 3 splicing and mutagenesis identify residues influencing cell surface density of heterologously expressed silkworm (Bombyx mori) glutamate-gated chloride channels

Exploring the pharmacological properties of insect nicotinic acetylcholine receptors

Fast, automated measurement of nematode swimming (thrashing) without morphometry

Functional and evolutionary insights from the genomes of three parasitoid Nasonia species

Functional characterisation of a nicotinic acetylcholine receptor α subunit from the brown dog tick, Rhipicephalus sanguineus

Functional genomics of ionotropic acetylcholine receptors in Caenorhabditis elegans and Drosophila melanogaster

Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans

Gene silencing of selected calcium-signalling molecules in a Drosophila cell line using double-stranded RNA interference

Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans

Insect nicotinic acetylcholine receptor gene families: from genetic model organism to vector, pest and beneficial species.

Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics

Ion channels: molecular targets of neuroactive insecticides

Is spinal muscular atrophy the result of defects in motor neuron processes?

Laser-light scattering diffusion measurements on brain microtubule protein from dogfish (Squalus acanthus) and beef ⬇️

Loops D, E and G in the Drosophila Dα1 subunit contribute to high neonicotinoid sensitivity of Dα1-chicken β2 nicotinic acetylcholine receptor.

Mechanisms of action, resistance and toxicity of insecticides targeting GABA receptors.

Modes of action, resistance and toxicity of insecticides targeting nicotinic acetylcholine receptors.

Motility of bovine spermatozoa studied by laser light scattering

Neonicotinoids show selective and diverse actions on their nicotinic receptor targets: electrophysiology, molecular biology, and receptor modeling studies.

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.

Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics.

Novel animal-health drug targets from ligand-gated chloride channels.

Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons.

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

Spectrometer for laser-light scattering measurements of macromolecular and subcellular particle motions

Strategies for automated analysis of C. elegans locomotion

Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms

Studies on an acetylcholine binding protein identify a basic residue in loop G on the β1 strand as a new structural determinant of neonicotinoid actions

Subtype-specific actions of beta-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4) expressed in Xenopus laevis oocytes

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.

The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum

The genome of the model beetle and pest Tribolium castaneum

The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera.

The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits

Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster

Tick Genome Assembled: New Opportunities for Research on Tick-Host-Pathogen Interactions

Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery?

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.