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Lista de obras de Bryan Paul Morgan

''Homologous restriction'' in complement lysis: roles of membrane complement regulators.

artículo científico publicado en 2005

2-Chloroadenosine inhibits complement-induced reactive oxygen metabolite production and recovery of human polymorphonuclear leucocytes attacked by complement

scientific article published on 01 January 1985

A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.

artículo científico publicado en 2015

A novel antibody against human factor B that blocks formation of the C3bB proconvertase and inhibits complement activation in disease models.

artículo científico publicado en 2014

A novel mutation in a patient with a deficiency of the eighth component of complement associated with recurrent meningococcal meningitis.

artículo científico publicado en 2009

A protein toxin from the sea anemone Phyllodiscus semoni targets the kidney and causes a severe renal injury with predominant glomerular endothelial damage

artículo científico publicado en 2007

A quantitative method for comparison of expression of alternatively spliced genes using different primer pairs

artículo científico publicado en 2005

A rapid method for the isolation of analogues of human CD59 by preparative SDS-PAGE: application to pig CD59

scientific article published on 01 February 1995

A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer ⬇️

artículo científico publicado el 22 de marzo de 2012

Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene.

artículo científico publicado en 2017

Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice.

artículo científico publicado en 2009

Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial

artículo científico publicado en 2015

Affinity purification of human factor H on polypeptides derived from streptococcal m protein: enrichment of the Y402 variant

artículo científico publicado en 2013

Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation.

artículo científico publicado en 2013

An abnormal but functionally active complement component C9 protein found in an Irish family with subtotal C9 deficiency.

artículo científico publicado en 2003

An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice

artículo científico publicado en 2015

Anti-disialoside antibodies kill perisynaptic Schwann cells and damage motor nerve terminals via membrane attack complex in a murine model of neuropathy.

artículo científico publicado en 2004

Antibody-independent activation of the classical complement pathway by cytomegalovirus-infected fibroblasts

scientific article published on 01 December 1998

Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.

artículo científico publicado en 2003

Antithyroid drugs and release of inflammatory mediators by complement-attacked thyroid cells

artículo científico publicado el 12 de septiembre de 1992

B cells from mice prematurely expressing human complement receptor type 2 are unresponsive to T-dependent antigens

artículo científico publicado en 2005

Beyond lysis: how complement influences cell fate.

artículo científico publicado en 2003

Biological activity, membrane-targeting modification, and crystallization of soluble human decay accelerating factor expressed in E. coli.

artículo científico publicado en 2004

Blockade of the C5a receptor fails to protect against experimental autoimmune encephalomyelitis in rats

artículo científico publicado en 2004

C3-dependent mechanism of microglial priming relevant to multiple sclerosis.

artículo científico publicado en 2012

CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells

artículo científico publicado en 2005

CD55 Deficiency Protects against Atherosclerosis in ApoE-Deficient Mice via C3a Modulation of Lipid Metabolism ⬇️

artículo científico publicado el 2 de agosto de 2011

CD55 in rat male reproductive tissue: differential expression in testis and expression of a unique truncated isoform on spermatozoa

scientific journal article

CD59 blockade enhances antigen-specific CD4+ T cell responses in humans: a new target for cancer immunotherapy?

artículo científico publicado en 2009

CD59 or C3 are not requred for angiotensin II-dependent hypertension or hypertrophy in mice.

artículo científico publicado en 2007

CD59 protects rat kidney from complement mediated injury in collaboration with crry

artículo científico publicado en 2000

CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens.

artículo científico publicado en 2007

CD59a is the primary regulator of membrane attack complex assembly in the mouse.

artículo científico publicado en 2004

CD93 regulates central nervous system inflammation in two mouse models of autoimmune encephalomyelitis

artículo científico publicado en 2018

Characterization in vitro and in vivo of the pig analogue of human CD59 using new monoclonal antibodies

artículo científico publicado en 1998

Characterization of a large genomic deletion in four Irish families with C7 deficiency.

artículo científico publicado en 2011

Characterization of the mouse analogues of CD59 using novel monoclonal antibodies: tissue distribution and functional comparison ⬇️

artículo científico publicado el 1 de mayo de 2003

Characterizing a pH-switch anti-C5 antibody as a tool for human and mouse complement C5 purification and cross-species inhibition of classical and reactive lysis

artículo científico publicado en 2018

Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice.

artículo científico publicado en 2008

Comparison of the suppressive effects of soluble CR1 and C5a receptor antagonist in acute arthritis induced in rats by blocking of CD59

artículo científico publicado en 2000

Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease

artículo científico publicado en 2016

Complement C3a receptors in the pituitary gland: a novel pathway by which an innate immune molecule releases hormones involved in the control of inflammation.

artículo científico publicado en 2003

Complement UK--how and why it started

artículo científico publicado en 2011

Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat

artículo científico publicado en 1998

Complement activation and expression during chronic relapsing experimental autoimmune encephalomyelitis in the Biozzi ABH mouse.

artículo científico publicado en 2015

Complement activation in leprosy: a retrospective study shows elevated circulating terminal complement complex in reactional leprosy

artículo científico publicado en 2016

Complement activation in multiple sclerosis plaques: an immunohistochemical analysis

artículo científico publicado en 2014

Complement activation on human neuroblastoma cell lines in vitro: route of activation and expression of functional complement regulatory proteins.

artículo científico publicado en 1996

Complement and clusterin in the spinal cord dorsal horn and gracile nucleus following sciatic nerve injury in the adult rat

artículo científico publicado en 1995

Complement and complement regulators in the male reproductive system

artículo científico publicado en 2006

Complement component C9 in Graves' disease

artículo científico publicado en 1986

Complement dysregulation and disease: From genes and proteins to diagnostics and drugs ⬇️

artículo científico publicado el 1 de noviembre de 2012

Complement in multiple sclerosis: its role in disease and potential as a biomarker.

artículo científico publicado en 2008

Complement in the pathogenesis of Alzheimer's disease.

artículo científico publicado en 2017

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

artículo científico publicado en 2016

Complement mediated cell death is associated with DNA fragmentation

artículo científico publicado en 2000

Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection.

artículo científico publicado en 2013

Complement membrane attack is required for endplate damage and clinical disease in passive experimental myasthenia gravis in Lewis rats

scientific article published on 01 November 2006

Complement regulation at the molecular level: The structure of decay-accelerating factor

artículo científico publicado en 2004

Complement regulation by Kaposi's sarcoma-associated herpesvirus ORF4 protein.

artículo científico publicado en 2003

Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells

artículo científico publicado en 1995

Complement regulator CD59 deficiency fails to augment susceptibility to actively induced experimental autoimmune myasthenia gravis.

artículo científico publicado en 2006

Complement regulator factor H as a serum biomarker of multiple sclerosis disease state.

artículo científico publicado en 2010

Complement regulator factor H in multiple sclerosis.

artículo científico publicado en 2011

Complement regulatory molecules: application to therapy and transplantation.

artículo científico publicado en 1995

Complement regulatory protein expression by a human oligodendrocyte cell line: cytokine regulation and comparison with astrocytes.

artículo científico publicado en 1996

Complement system activation contributes to the ependymal damage induced by microbial neuraminidase.

artículo científico publicado en 2016

Complement system biomarkers in epilepsy

artículo científico publicado en 2018

Complement system biomarkers in first episode psychosis

artículo científico publicado en 2017

Complement therapeutics; history and current progress.

artículo científico publicado en 2003

Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis

artículo científico publicado en 2011

Complement, a target for therapy in inflammatory and degenerative diseases.

artículo científico publicado en 2015

Complement, roles in renal disease and modulation for therapy.

artículo científico publicado en 2008

Complement-mediated lysis of pigeon erythrocyte ghosts analysed by flow cytometry. Evidence for the involvement of a 'threshold' phenomenon.

artículo científico publicado en 1983

Complement: central to innate immunity and bridging to adaptive responses.

artículo científico publicado en 2004

Complementing the inflammasome.

artículo científico publicado en 2015

Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99].

artículo científico publicado en 2013

Cross-linking of CD59 and of other glycosyl phosphatidylinositol-anchored molecules on neutrophils triggers cell activation via tyrosine kinase

artículo científico publicado en 1993

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury

scientific journal article

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers

artículo científico publicado en 2018

Cutting edge: murine CD59a modulates antiviral CD4+ T cell activity in a complement-independent manner

artículo científico publicado en 2005

Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release.

artículo científico publicado en 2013

Cytokine-mediated up-regulation of CD55 and CD59 protects human hepatoma cells from complement attack.

artículo científico publicado en 2000

Decay-accelerating factor must bind both components of the complement alternative pathway C3 convertase to mediate efficient decay

scientific journal article

Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis

artículo científico publicado en 2004

Deficiency of the complement regulator CD59a exacerbates Wallerian degeneration.

artículo científico publicado en 2009

Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.

artículo científico publicado en 2012

Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis

scientific article published on 01 September 2004

Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice.

artículo científico publicado en 2015

Development of a model for cytomegalovirus infection of oligodendrocytes.

artículo científico publicado en 1997

Dimerization of complement factor H-related proteins modulates complement activation in vivo

artículo científico publicado en 2013

Discovery of omecamtiv mecarbil the first, selective, small molecule activator of cardiac Myosin.

artículo científico publicado en 2010

Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay

artículo científico publicado en 2013

Distribution of membrane cofactor protein (MCP/CD46) on pig tissues. Relevance To xenotransplantation

artículo científico publicado en 1999

Editorial

artículo científico publicado en 2016

Effects of inhibition of complement activation using recombinant soluble complement receptor 1 on neutrophil CD11b/CD18 and L-selectin expression and release of interleukin-8 and elastase in simulated cardiopulmonary bypass

artículo científico publicado en 1996

Efficient generation of monoclonal antibodies for specific protein domains using recombinant immunoglobulin fusion proteins: pitfalls and solutions.

artículo científico publicado en 2002

Enhanced complement susceptibility of avidin-biotin-treated human erythrocytes is a consequence of neutralization of the complement regulators CD59 and decay accelerating factor.

artículo científico publicado en 1995

Epitope mapping of 10 monoclonal antibodies against the pig analogue of human membrane cofactor protein (MCP)

artículo científico publicado en 1999

Evidence for activation of the terminal pathway of complement and upregulation of sulfated glycoprotein (SGP)-2 in the hypoglossal nucleus following peripheral nerve injury

scientific article published on 01 January 1995

Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent ⬇️

artículo científico publicado el 1 de noviembre de 1995

Exploiting the nephrotoxic effects of venom from the sea anemone, Phyllodiscus semoni, to create a hemolytic uremic syndrome model in the rat

artículo científico publicado en 2012

Expression and function of membrane regulators of complement on rat astrocytes in culture

artículo científico publicado en 1996

Expression of CD46 in developing rat spermatozoa: ultrastructural localization and utility as a marker of the various stages of the seminiferous tubuli

scientific journal article

Expression of human complement receptor type 2 (CD21) in mice during early B cell development results in a reduction in mature B cells and hypogammaglobulinemia.

artículo científico publicado en 2002

Expression of rat CD59: functional analysis confirms lack of species selectivity and reveals that glycosylation is not required for function

artículo científico publicado en 1997

Expression of the glycosylphosphatidylinositol-linked complement-inhibiting protein CD59 antigen in insect cells using a baculovirus vector ⬇️

artículo científico publicado el 1 de noviembre de 1993

Extracting the barbs from complement assays: Identification and optimisation of a safe substitute for traditional buffers

artículo científico publicado en 2018

Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis

artículo científico publicado en 2015

Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B

scholarly article

Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo.

artículo científico publicado en 2003

Genetic analysis and functional characterization of novel mutations in a series of patients with atypical hemolytic uremic syndrome.

artículo científico publicado en 2016

Glomerular complement regulation is overwhelmed in passive Heymann nephritis

scientific article published on 01 September 2001

Glycation of CD59 impairs complement regulation on erythrocytes from diabetic subjects.

artículo científico publicado en 2005

Glycosylation and the complement system.

artículo científico publicado en 2002

Hereditary angioedema--therapies old and new.

artículo científico publicado en 2010

Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9.

artículo científico publicado en 2017

High Levels of Soluble C5b-9 Complex in Dialysis Fluid May Predict Poor Prognosis in Peritonitis in Peritoneal Dialysis Patients

artículo científico publicado en 2017

High-resolution structures of bacterially expressed soluble human CD59

artículo científico publicado en 2007

Holding T cells in check--a new role for complement regulators?

artículo científico publicado en 2006

Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q

artículo científico publicado en 2002

Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59

artículo científico publicado en 1994

Human diffusely adhering Escherichia coli expressing Afa/Dr adhesins that use human CD55 (decay-accelerating factor) as a receptor does not bind the rodent and pig analogues of CD55

artículo científico publicado en 2004

Human factor H-related protein 5 (FHR-5). A new complement-associated protein

artículo científico publicado en 2001

Identification of an Astrocyte Cell Population from Human Brain that Expresses Perforin, a Cytotoxic Protein Implicated in Immune Defense ⬇️

artículo científico publicado el 16 de febrero de 1998

Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.

artículo científico publicado en 2014

Identification of the individual residues that determine human CD59 species selective activity

artículo científico publicado en 1999

Immunization with autologous CD46 generates a strong autoantibody response in rats that targets spermatozoa.

artículo científico publicado en 2006

Immunocytochemical localization of the terminal complement complex in multiple sclerosis.

artículo científico publicado en 1989

Immunoradiometric assay for human complement component C9 utilising monoclonal antibodies

scientific article published on 01 October 1983

Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.

artículo científico publicado en 2010

Implication of Complement System and its Regulators in Alzheimer’s Disease

artículo científico publicado en 2009

In vivo characterization and therapeutic efficacy of a C5-specific inhibitor from the soft tick Ornithodoros moubata

scientific article published on 10 January 2007

Inhibition of complement-induced [14C]sucrose release by intracellular and extracellular monoclonal antibodies to C9: evidence that C9 is a transmembrane protein

artículo científico publicado en 1984

Inhibition of coxsackie B virus infection by soluble forms of its receptors: binding affinities, altered particle formation, and competition with cellular receptors.

artículo científico publicado en 2005

Inhibition of the Membrane Attack Complex of the Complement System Reduces Secondary Neuroaxonal Loss and Promotes Neurologic Recovery after Traumatic Brain Injury in Mice

artículo científico publicado en 2014

Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation

artículo científico publicado en 2013

Intervention in the complement system: a therapeutic strategy in inflammation.

artículo científico publicado en 1996

Into the third century of complement research

artículo científico publicado en 2000

Intracellular Ca2+ and cell injury: a paradoxical role of Ca2+ in complement membrane attack.

artículo científico publicado en 1986

Introduction to complement in health and disease: novel aspects and insights

artículo científico publicado en 2018

Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement ⬇️

artículo científico publicado el 15 de mayo de 1992

Isolation and characterization of a membrane-attack-complex-inhibiting protein present in human serum and other biological fluids

artículo científico publicado en 1990

Isolation and characterization of the complement-inhibiting protein CD59 antigen from platelet membranes ⬇️

artículo científico publicado el 1 de marzo de 1992

Killing of cells by perforin. Resistance to killing is not due to diminished binding of perforin to the cell membrane ⬇️

artículo científico publicado el 15 de noviembre de 1991

Killing of rat glial cells by complement: deficiency of the rat analogue of CD59 is the cause of oligodendrocyte susceptibility to lysis

artículo científico publicado en 1993

Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway.

artículo científico publicado en 2010

Letter in response to A. Agrawal: 'CRP after 2004'

scientific article published on 01 February 2006

Local therapy with soluble complement receptor 1 (sCR1) suppresses inflammation in rat mono-articular arthritis

artículo científico publicado en 1997

M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator.

artículo científico publicado en 2015

Mapping the regions of the complement inhibitor CD59 responsible for its species selective activity

artículo científico publicado en 1997

Measurement of C9 concentrations using an immunochemiluminometric assay

Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration

artículo científico publicado en 2008

Measurement of soluble CD59 in CSF in demyelinating disease: Evidence for an intrathecal source of soluble CD59.

artículo científico publicado en 2018

Mechanisms of complement resistance induced by non-lethal complement attack and by growth arrest

scientific article published on 01 April 1997

Membrane attack complex formation on yeast as trigger of selective release of terminal complement proteins from human polymorphonuclear leukocytes

artículo científico publicado en 2000

Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats.

artículo científico publicado en 2012

Membrane complement regulators protect against the development of type II collagen-induced arthritis in rats

scientific article published on 01 October 2001

Mice expressing human CR1/CD35 have an enhanced humoral immune response to T-dependent antigens but fail to correct the effect of premature human CR2 expression ⬇️

artículo científico publicado el 25 de junio de 2011

Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation

artículo científico publicado en 2017

Miller Fisher anti-GQ1b antibodies: alpha-latrotoxin-like effects on motor end plates

artículo científico publicado en 1999

Molecular and functional analysis of mouse decay accelerating factor (CD55)

artículo científico publicado en 1999

Molecular cell biology of complement membrane attack.

artículo científico publicado en 2017

Molecular cloning of the rat analogue of human CD59: structural comparison with human CD59 and identification of a putative active site

scientific journal article

Molecular cloning, expression and characterization of the rat analogue of human membrane cofactor protein (MCP/CD46)

artículo científico publicado en 1999

Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55).

artículo científico publicado en 2004

Molecular pathogenesis of human CD59 deficiency

artículo científico publicado en 2018

Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status.

artículo científico publicado en 2007

Myelin-oligodendrocyte glycoprotein (MOG) is a surface marker of oligodendrocyte maturation

scientific article published on 01 May 1989

Non-lethal doses of antibody and complement stimulate release of prostaglandin E2 from human amniotic cells in vitro

artículo científico publicado en 1990

Normal rat serum cytotoxicity against syngeneic oligodendrocytes. Complement activation and attack in the absence of anti-myelin antibodies.

artículo científico publicado en 1989

Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

artículo científico publicado en 1997

Photoproteins as indicators of intracellular free Ca2+

scientific article published on 01 July 1989

Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysis

artículo científico publicado en 1993

Physiology and pathophysiology of complement: progress and trends.

artículo científico publicado en 1995

Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder.

artículo científico publicado en 2016

Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis

artículo científico publicado en 2012

Production and functional analysis of rat CD59 and chimeric CD59-Crry as active soluble proteins in Pichia pastoris

scientific article published on 01 January 2000

Production and functional characterization of a soluble recombinant form of mouse CD59

artículo científico publicado en 2000

Protection of human breast cancer cells from complement-mediated lysis by expression of heterologous CD59.

artículo científico publicado en 1999

Rat T cells express neither CD55 nor CD59 and are dependent on Crry for protection from homologous complement

artículo científico publicado en 2002

Rat membrane cofactor protein (MCP; CD46) is expressed only in the acrosome of developing and mature spermatozoa and mediates binding to immobilized activated C3

scientific journal article

Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice.

artículo científico publicado en 2010

Respective roles of decay-accelerating factor and CD59 in circumventing glomerular injury in acute nephrotoxic serum nephritis

artículo científico publicado en 2004

Response to Comment on "Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis"

artículo científico publicado en 2015

Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease

artículo científico publicado en 2020

Retraction notice to "The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility" [Mol. Immunol. 45 (2008) 534-542]

article published in 2014

Retraction: Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms

artículo científico publicado en 2011

Role and regulation of pig CD59 and membrane cofactor protein/CD46 expressed on pig aortic endothelial cells

scientific article published on 01 August 2000

Role of CD59 in experimental glomerulonephritis in rats

scientific article published on 01 July 1994

Role of complement in the aetiology of Pick's disease?

artículo científico publicado en 1996

Role of complement regulatory membrane proteins in ischaemia-reperfusion injury of rat gastric mucosa

scientific article published on 01 October 1999

Role of the Complement Pathway in Inflammatory Skin Diseases: A Focus on Hidradenitis Suppurativa

scientific article published on 20 December 2019

Roles for glycosylation in the anti-inflammatory molecule CD59.

artículo científico publicado en 1997

Roles of the complement system in human neurodegenerative disorders: pro-inflammatory and tissue remodeling activities.

artículo científico publicado en 2002

Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation

artículo científico publicado en 2012

Signalling through neutrophil Fc gamma RIII, Fc gamma RII, and CD59 is not impaired in active rheumatoid arthritis.

artículo científico publicado en 1996

Soluble complement receptor 1 (sCR1) protects against experimental autoimmune myasthenia gravis

artículo científico publicado en 1996

Soluble complement receptor 1 protects the peripheral nerve from early axon loss after injury.

artículo científico publicado en 2008

Soluble complement receptor one (sCR1) inhibits the development and progression of rat collagen-induced arthritis

scientific article published on 01 January 2000

Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice

artículo científico publicado en 2018

Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation

artículo científico publicado en 2010

Spermatogenic cells distal to the blood-testis barrier in rats lack C3 convertase regulators and may be at risk of complement-mediated injury.

artículo científico publicado en 2005

Sphingomyelinases in the venom of the spider Loxosceles intermedia are responsible for both dermonecrosis and complement-dependent hemolysis

artículo científico publicado en 1998

Structural basis of complement membrane attack complex formation.

artículo científico publicado en 2016

Structures of the rat complement regulator CrrY

artículo científico publicado en 2011

Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration.

artículo científico

Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU).

artículo científico publicado en 2010

Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis.

artículo científico publicado en 2009

Systemic complement profiling in multiple sclerosis as a biomarker of disease state.

artículo científico publicado en 2012

Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis.

artículo científico publicado en 2018

Target-sensitive immunoerythrocytes: interaction of biotinylated red blood cells with immobilized avidin induces their lysis by complement

scientific article published on 01 March 1996

Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria

article

Terminal complexes of the complement system: new structural insights and their relevance to function.

artículo científico publicado en 2016

Terminal component of complement (C9) in cerebrospinal fluid of patients with multiple sclerosis

artículo científico publicado en 1984

The Glycosylation of the Complement Regulatory Protein, Human Erythrocyte CD59

artículo científico publicado en 1997

The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury

scientific article published on 01 January 2002

The Membrane Attack Complex of the Complement System Is Essential for Rapid Wallerian Degeneration

artículo científico publicado en 2007

The administration of complement component C9 enhances the survival of neonatal rats with Escherichia coli sepsis.

artículo científico publicado en 1997

The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury

artículo científico publicado en 2010

The complement-inhibiting protein, Protectin (CD59 antigen), is present and functionally active on glomerular epithelial cells ⬇️

artículo científico publicado el 1 de febrero de 1991

The distribution of inflammatory demyelinated lesions in the central nervous system of rats with antibody-augmented demyelinating experimental allergic encephalomyelitis.

artículo científico publicado en 1994

The effect of soluble complement receptor 1 (sCR1) and human thyroid antibodies on the course of experimental autoimmune thyroiditis in rats

scientific article published on 01 January 1996

The expression of complement regulatory proteins by adult human oligodendrocytes

scientific article published on 01 April 1998

The human complement fragment receptor, C5L2, is a recycling decoy receptor.

artículo científico publicado en 2008

The lipopolysaccharide co-receptor CD14 is present and functional in seminal plasma and expressed on spermatozoa

artículo científico publicado en 2001

The membrane attack complex as an inflammatory trigger

artículo científico

The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice

artículo científico publicado en 2009

The membrane attack pathway of complement drives pathology in passively induced experimental autoimmune myasthenia gravis in mice

scientific article published on 01 November 2006

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.

artículo científico publicado en 2015

The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility.

artículo científico publicado en 2007

The pig analogue of CD59 protects transgenic mouse hearts from injury by human complement

scientific article published on 01 September 2000

The possibilities and pitfalls for anti-complement therapies in inflammatory diseases.

artículo científico publicado en 2004

The role of calcium in rat oligodendrocyte injury and repair

artículo científico publicado en 1992

The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barré syndrome.

artículo científico publicado en 2008

The role of complement in disorders of the nervous system ⬇️

artículo científico publicado el 1 de diciembre de 1997

The role of complement in neurological and neuropsychiatric diseases.

artículo científico

The role of complement in the pathogenesis of experimental allergic encephalomyelitis

scientific article published on 01 August 1989

Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex

artículo científico publicado en 2016

Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis

artículo científico publicado en 2017

Transfected CD59 protects mesangial cells from injury induced by antibody and complement

artículo científico publicado en 1996

Transience of membrane channels induced by perforin and by the membrane attack complex

artículo científico publicado en 1990

Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement ⬇️

artículo científico publicado el 1 de noviembre de 1995

Tumour cell killing using chemically engineered antibody constructs specific for tumour cells and the complement inhibitor CD59

scientific article published on 01 February 1997

Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration

artículo científico publicado en 2009

Vaccination against meningococcus in complement-deficient individuals.

artículo científico publicado en 1998

Variation in complement component C1 inhibitor in age-related macular degeneration

artículo científico publicado en 2011

Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement

artículo científico publicado en 1989

Zymosan, but not lipopolysaccharide, triggers severe and progressive peritoneal injury accompanied by complement activation in a rat peritonitis model.

artículo científico publicado en 2009

p53 regulates cellular resistance to complement lysis through enhanced expression of CD59

artículo científico publicado en 2006

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