Lista de obras - Sebastian Bauer - Dominio Público Uruguay

5-ALA-mediated fluorescence of musculoskeletal tumors in a chick chorio-allantoic membrane model: preclinical in vivo qualification analysis as a fluorescence-guided surgery agent in Orthopedic Oncology

artículo científico publicado en 2022

A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor.

artículo científico publicado en 2010

A phase II study of a human anti-PDGFRα monoclonal antibody (olaratumab, IMC-3G3) in previously treated patients with metastatic gastrointestinal stromal tumors.

artículo científico publicado en 2017

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 'CREATE'.

artículo científico publicado en 2017

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 ‘CREATE’

artículo científico publicado en 2019

Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3. European Organization for Research and Treatment of Cancer (EORTC) phase 2 trial 90101 "CREATE".

artículo científico publicado en 2017

Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes.

artículo científico publicado en 2011

Adjuvant Imatinib for High-Risk GI Stromal Tumor: Analysis of a Randomized Trial

artículo científico publicado en 2015

Adjuvant chemotherapy for soft tissue sarcoma? a clear no - well - yes-ish

artículo científico publicado en 2013

Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA

artículo científico publicado en 2024

Avelumab in patients with previously treated metastatic adrenocortical carcinoma: phase 1b results from the JAVELIN solid tumor trial

scholarly article by Christophe Le Tourneau et al published 22 October 2018 in Journal for Immunotherapy of Cancer

Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial

artículo científico publicado en 2019

Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

scientific article published on 22 February 2019

Correlation of CTNNB1 Mutation Status with Progression Arrest Rate in RECIST Progressive Desmoid-Type Fibromatosis Treated with Imatinib: Translational Research Results from a Phase 2 Study of the German Interdisciplinary Sarcoma Group (GISG-01).

artículo científico publicado en 2016

Covalent-Allosteric Kinase Inhibitors.

artículo científico publicado en 2015

Cytomegalovirus induces apoptosis in acute leukemia cells as a virus-versus-leukemia function.

artículo científico publicado en 2015

DOG1 regulates growth and IGFBP5 in gastrointestinal stromal tumors.

artículo científico publicado en 2013

Desmoplastic small round cell tumors: Multimodality treatment and new risk factors

artículo científico publicado en 2019

Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib: An Exploratory Analysis of a Randomized Clinical Trial

artículo científico

Eltrombopag for thrombocytopenia in patients with advanced solid tumors receiving gemcitabine-based chemotherapy: a randomized, placebo-controlled phase 2 study.

artículo científico publicado en 2017

Emerging Agents for the Treatment of Advanced, Imatinib-Resistant Gastrointestinal Stromal Tumors: Current Status and Future Directions

artículo científico publicado en 2015

Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

artículo científico publicado en 2016

Evaluation of 47 soft tissue sarcoma resection specimens after isolated limb perfusion with TNF-alpha and melphalan: histologically characterized improved margins correlate with absence of recurrences

artículo científico publicado en 2009

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

artículo científico publicado en 2018

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

artículo científico publicado en 2018

Gemcitabine in the treatment of soft tissue sarcomas.

artículo científico publicado en 2004

Growth patterns of lung metastases from sarcoma: prognostic and surgical implications from histology.

artículo científico publicado en 2012

Growth patterns of lung metastases from sarcomas

artículo científico publicado en 2011

Head and Neck Kaposi Sarcoma: Clinicopathological Analysis of 11 Cases

artículo científico publicado en 2018

Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.

artículo científico publicado en 2006

Imatinib induces sustained progression arrest in RECIST progressive desmoid tumours: Final results of a phase II study of the German Interdisciplinary Sarcoma Group (GISG).

artículo científico publicado en 2017

Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.

artículo científico publicado en 2002

Inhibition of KIT-glycosylation by 2-deoxyglucose abrogates KIT-signaling and combination with ABT-263 synergistically induces apoptosis in gastrointestinal stromal tumor.

artículo científico publicado en 2015

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

scientific article published on 04 October 2019

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

scientific article published on 04 May 2016

Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.

artículo científico publicado en 2017

Integrative genomic and transcriptomic analysis of leiomyosarcoma.

artículo científico publicado en 2018

Intimal sarcoma of the pulmonary artery with unusual findings: a case report

artículo científico publicado en 2012

KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy

artículo científico publicado en 2019

Locally advanced and metastatic sarcoma (adult type) including gastrointestinal stromal tumors.

artículo científico publicado en 2006

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib -- analysis of prognostic factors (EORTC-STBSG collaborative study).

artículo científico publicado en 2014

Long-term outcome of dasatinib first-line treatment in gastrointestinal stromal tumor: A multicenter, 2-stage phase 2 trial (Swiss Group for Clinical Cancer Research 56/07).

artículo científico publicado en 2018

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

artículo científico publicado en 2014

Lower limb function and quality of life after ILP for soft-tissue sarcoma

artículo científico publicado en 2017

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation.

artículo científico publicado en 2017

Mammalian target of rapamycin pathway activity in alveolar soft part sarcoma.

artículo científico publicado en 2013

Molecular subtypes of gastrointestinal stromal tumor requiring specific treatments.

artículo científico publicado en 2016

Multimodality treatment including surgery for primary pulmonary sarcoma: Size does matter

artículo científico publicado en 2020

Needle biopsy through the abdominal wall for the diagnosis of gastrointestinal stromal tumour - Does it increase the risk for tumour cell seeding and recurrence?

artículo científico publicado en 2016

Neoadjuvant treatment improves capsular integrity and the width of the fibrous capsule of high-grade soft-tissue sarcomas

artículo científico publicado en 2012

One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial.

artículo científico publicado en 2012

Optimal Avapritinib Treatment Strategies for Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors

scientific article published on 10 December 2020

Optimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing.

artículo científico publicado en 2005

Options for treating different soft tissue sarcoma subtypes

artículo científico publicado en 2018

Pemetrexed in patients with refractory soft tissue sarcoma: A non-comparative multicenter phase II study of the German Sarcoma Group AIO-STS 005 ⬇️

artículo científico publicado el 5 de julio de 2012

Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

artículo científico publicado en 2014

Plastic Surgery in Palliative Care - Report on the Consensus Workshop of the 37th Annual Meeting of the German-language Group for Microsurgery of the Peripheral Nerves and Vessels (DAM) 2016 in Bochum

artículo científico publicado en 2016

Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients.

artículo científico publicado en 2014

Postoperative FDG-PET/CT staging in GIST: Is there a benefit following R0 resection? ⬇️

artículo científico publicado el 22 de octubre de 2010

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey.

artículo científico publicado en 2017

Preclinical models for translational sarcoma research

artículo científico publicado en 2017

Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells

artículo científico publicado en 2009

Prognostic relevance of soluble human leukocyte antigen–G and total human leukocyte antigen class I molecules in lung cancer patients

artículo científico publicado en 2010

Pulmonary metastasectomy for sarcoma-Essen experience.

artículo científico publicado en 2017

Rational promoter selection for gene transfer into cardiac cells.

artículo científico publicado en 2003

Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?

artículo científico publicado en 2018

Resection of residual disease in patients with metastatic gastrointestinal stromal tumors responding to treatment with imatinib.

artículo científico publicado en 2005

Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain

scientific article published on 24 September 2020

Results for patients with sarcoma not otherwise specified and other diagnoses than Ewing sarcoma treated according to the Euro-EWING 99 trial

artículo científico publicado en 2017

Risk factors for gastrointestinal stromal tumor recurrence in patients treated with adjuvant imatinib.

artículo científico publicado en 2014

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

artículo científico publicado en 2018

Somatostatin receptor scintigraphy in advanced renal cell carcinoma. Results of a phase II-trial of somatostatine analogue therapy in patients with advanced RCC.

artículo científico publicado en 2008

Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis.

artículo científico publicado en 2012

Survivin is a novel transcription regulator of KIT and is downregulated by miRNA-494 in gastrointestinal stromal tumors.

artículo científico publicado en 2017

Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors.

artículo científico publicado en 2016

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway

artículo científico publicado en 2015

The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15.

artículo científico publicado en 2016

Trabectedin in metastatic soft tissue sarcomas: Role of pretreatment and age ⬇️

artículo científico publicado el 2 de mayo de 2013

Translational insights into gastrointestinal stromal tumor and current clinical advances

artículo científico publicado en 2018

Treatment of gastrointestinal stromal tumor after imatinib and sunitinib.

artículo científico publicado en 2011

Tumor vascularization and histopathologic regression of soft tissue sarcomas treated with isolated limb perfusion with TNF-α and melphalan

artículo científico publicado en 2011

[Gastrointestinal stromal tumours (GIST)--development in pathology, surgery and medical therapy. Developed during the 10th German GIST-meeting, Göttingen].

artículo científico publicado en 2015

[Individualized tumor therapy and status quo in melanoma].

artículo científico publicado en 2012

[Isolated limb perfusion for liposarcoma : Histopathological response and subgroup analysis after TNF melphalan-based ILP].

artículo científico publicado en 2017

Lista de obras de Sebastian Bauer

5-ALA-mediated fluorescence of musculoskeletal tumors in a chick chorio-allantoic membrane model: preclinical in vivo qualification analysis as a fluorescence-guided surgery agent in Orthopedic Oncology

A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor.

A phase II study of a human anti-PDGFRα monoclonal antibody (olaratumab, IMC-3G3) in previously treated patients with metastatic gastrointestinal stromal tumors.

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 'CREATE'.

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 ‘CREATE’

Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3. European Organization for Research and Treatment of Cancer (EORTC) phase 2 trial 90101 "CREATE".

Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes.

Adjuvant Imatinib for High-Risk GI Stromal Tumor: Analysis of a Randomized Trial

Adjuvant chemotherapy for soft tissue sarcoma? a clear no - well - yes-ish

Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA

Avelumab in patients with previously treated metastatic adrenocortical carcinoma: phase 1b results from the JAVELIN solid tumor trial

Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial

Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

Correlation of CTNNB1 Mutation Status with Progression Arrest Rate in RECIST Progressive Desmoid-Type Fibromatosis Treated with Imatinib: Translational Research Results from a Phase 2 Study of the German Interdisciplinary Sarcoma Group (GISG-01).

Covalent-Allosteric Kinase Inhibitors.

Cytomegalovirus induces apoptosis in acute leukemia cells as a virus-versus-leukemia function.

DOG1 regulates growth and IGFBP5 in gastrointestinal stromal tumors.

Desmoplastic small round cell tumors: Multimodality treatment and new risk factors

Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib: An Exploratory Analysis of a Randomized Clinical Trial

Eltrombopag for thrombocytopenia in patients with advanced solid tumors receiving gemcitabine-based chemotherapy: a randomized, placebo-controlled phase 2 study.

Emerging Agents for the Treatment of Advanced, Imatinib-Resistant Gastrointestinal Stromal Tumors: Current Status and Future Directions

Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

Evaluation of 47 soft tissue sarcoma resection specimens after isolated limb perfusion with TNF-alpha and melphalan: histologically characterized improved margins correlate with absence of recurrences

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

Gemcitabine in the treatment of soft tissue sarcomas.

Growth patterns of lung metastases from sarcoma: prognostic and surgical implications from histology.

Growth patterns of lung metastases from sarcomas

Head and Neck Kaposi Sarcoma: Clinicopathological Analysis of 11 Cases

Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.

Imatinib induces sustained progression arrest in RECIST progressive desmoid tumours: Final results of a phase II study of the German Interdisciplinary Sarcoma Group (GISG).

Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.

Inhibition of KIT-glycosylation by 2-deoxyglucose abrogates KIT-signaling and combination with ABT-263 synergistically induces apoptosis in gastrointestinal stromal tumor.

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.

Integrative genomic and transcriptomic analysis of leiomyosarcoma.

Intimal sarcoma of the pulmonary artery with unusual findings: a case report

KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy

Locally advanced and metastatic sarcoma (adult type) including gastrointestinal stromal tumors.

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib -- analysis of prognostic factors (EORTC-STBSG collaborative study).

Long-term outcome of dasatinib first-line treatment in gastrointestinal stromal tumor: A multicenter, 2-stage phase 2 trial (Swiss Group for Clinical Cancer Research 56/07).

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

Lower limb function and quality of life after ILP for soft-tissue sarcoma

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation.

Mammalian target of rapamycin pathway activity in alveolar soft part sarcoma.

Molecular subtypes of gastrointestinal stromal tumor requiring specific treatments.

Multimodality treatment including surgery for primary pulmonary sarcoma: Size does matter

Needle biopsy through the abdominal wall for the diagnosis of gastrointestinal stromal tumour - Does it increase the risk for tumour cell seeding and recurrence?

Neoadjuvant treatment improves capsular integrity and the width of the fibrous capsule of high-grade soft-tissue sarcomas

One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial.

Optimal Avapritinib Treatment Strategies for Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors

Optimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing.

Options for treating different soft tissue sarcoma subtypes

Pemetrexed in patients with refractory soft tissue sarcoma: A non-comparative multicenter phase II study of the German Sarcoma Group AIO-STS 005 ⬇️

Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

Plastic Surgery in Palliative Care - Report on the Consensus Workshop of the 37th Annual Meeting of the German-language Group for Microsurgery of the Peripheral Nerves and Vessels (DAM) 2016 in Bochum

Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients.

Postoperative FDG-PET/CT staging in GIST: Is there a benefit following R0 resection? ⬇️

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey.

Preclinical models for translational sarcoma research

Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells

Prognostic relevance of soluble human leukocyte antigen–G and total human leukocyte antigen class I molecules in lung cancer patients

Pulmonary metastasectomy for sarcoma-Essen experience.

Rational promoter selection for gene transfer into cardiac cells.

Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?

Resection of residual disease in patients with metastatic gastrointestinal stromal tumors responding to treatment with imatinib.

Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain

Results for patients with sarcoma not otherwise specified and other diagnoses than Ewing sarcoma treated according to the Euro-EWING 99 trial

Risk factors for gastrointestinal stromal tumor recurrence in patients treated with adjuvant imatinib.

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

Somatostatin receptor scintigraphy in advanced renal cell carcinoma. Results of a phase II-trial of somatostatine analogue therapy in patients with advanced RCC.

Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis.

Survivin is a novel transcription regulator of KIT and is downregulated by miRNA-494 in gastrointestinal stromal tumors.

Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors.

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway

The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15.

Trabectedin in metastatic soft tissue sarcomas: Role of pretreatment and age ⬇️

Translational insights into gastrointestinal stromal tumor and current clinical advances