"Emerging Alzheimer's disease therapies: focusing on the future".
artículo científico publicado en 2002
"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).
artículo científico publicado en 2016
'Unfolding' pathways in neurodegenerative disease
artículo científico publicado en 2003
12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress
artículo científico publicado en 2004
17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions
artículo científico publicado en 2004
1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France
article
2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception
artículo científico publicado en 2015
3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects
artículo científico publicado en 2010
A "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport
artículo científico publicado en 2011
A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes.
artículo científico publicado en 2018
A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment
artículo científico publicado en 2018
A Review and Rationale for the Use of Cellular Transplantation as a Therapeutic Strategy for Traumatic Brain Injury
A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model
artículo científico publicado en 2018
A case study of an emerging visual artist with frontotemporal lobar degeneration and amyotrophic lateral sclerosis
artículo científico publicado en 2009
A combined horseradish peroxidase-autoradiographic investigation of reciprocal connections between superior temporal gyrus and pulvinar in squirrel monkey
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artículo científico publicado el 28 de febrero de 1975
A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis
artículo científico publicado en 2014
A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114.
artículo científico publicado en 2003
A comprehensive screening of copy number variability in dementia with Lewy bodies
scientific article published on 24 October 2018
A detailed immunohistochemical analysis of cerebellar hemangioblastoma: an undifferentiated mesenchymal tumor
artículo científico publicado en 1989
A distinct familial presenile dementia with a novel missense mutation in the tau gene
artículo científico publicado en 1999
A framework for informing segmentation of in vivo MRI with information derived from ex vivo imaging: Application in the medial temporal lobe
artículo científico publicado en 2016
A harmonized classification system for FTLD-TDP pathology
artículo científico publicado en 2011
A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.
artículo científico publicado en 2000
A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury
artículo científico publicado en 2008
A model for improving the treatment and care of Alzheimer's disease patients through interdisciplinary research
artículo científico publicado en 2012
A morphometric study of the endocytosis of wheat germ agglutinin-horseradish peroxidase conjugates by retinal ganglion cells in the rat
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artículo científico publicado el 8 de agosto de 1983
A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies
artículo científico publicado en 2013
A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau deposition
artículo científico publicado en 2010
A neuroattenuated ICP34.5-deficient herpes simplex virus type 1 replicates in ependymal cells of the murine central nervous system
artículo científico publicado en 1998
A new consensus report on biomarkers for the early antemortem diagnosis of Alzheimer disease: current status, relevance to drug discovery, and recommendations for future research.
artículo científico publicado en 1998
A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases
artículo científico publicado en 2014
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease
artículo científico publicado en 2009
A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease
artículo científico publicado en 2000
A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank
artículo científico publicado en 2013
A rapidly dividing human medulloblastoma cell line (D283 MED) expresses all three neurofilament subunits
artículo científico publicado en 1987
A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury
artículo científico publicado en 2004
A review and rationale for the use of genetically engineered animals in the study of traumatic brain injury
artículo científico publicado en 2001
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008.
artículo científico publicado en 2009
A yeast functional screen predicts new candidate ALS disease genes
artículo científico publicado en 2011
A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred
artículo científico publicado en 1993
A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.
artículo científico publicado en 1991
A90V TDP-43 variant results in the aberrant localization of TDP-43 in vitro
artículo científico publicado en 2008
ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies
artículo científico publicado en 2020
AMY plaques in familial AD: comparison with sporadic Alzheimer's disease
artículo científico publicado en 2000
APOE Effect on Amyloid-β PET Spatial Distribution, Deposition Rate, and Cut-Points
artículo científico publicado en 2019
APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern
artículo científico publicado en 2015
APOE ε4 increases risk for dementia in pure synucleinopathies
artículo científico publicado en 2013
APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease
artículo científico publicado en 2014
APOE, thought disorder, and SPARE-AD predict cognitive decline in established Parkinson's disease
artículo científico publicado en 2017
ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration
artículo científico publicado en 2020
ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration
artículo científico publicado en 2020
Abnormal expression of two microtubule-associated proteins (MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia
scientific article published on December 1991
Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies
artículo científico publicado en 2014
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
artículo científico publicado en 1993
Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease
artículo científico publicado en 2014
Absence of association of alpha1-antichymotrypsin polymorphisms with Alzheimer's disease: a report on autopsy-confirmed cases
artículo científico publicado en 1998
Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration
artículo científico publicado en 2007
Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia
artículo científico publicado en 1998
Abundance of apoptotic neoplastic cells in diagnostic biopsy samples is not a prognostic factor in childhood primitive neuroectodermal tumors of the central nervous system
artículo científico publicado en 2001
Acalculia in Autopsy-Proven Corticobasal Degeneration
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artículo científico publicado el 15 de febrero de 2011
Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig.
artículo científico publicado en 1999
Acetylated tau neuropathology in sporadic and hereditary tauopathies
artículo científico publicado en 2013
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
artículo científico publicado en 2012
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
artículo científico publicado en 2016
Active Cigarette Smoking in Cognitively-Normal Elders and Probable Alzheimer's Disease is Associated with Elevated Cerebrospinal Fluid Oxidative Stress Biomarkers
scientific article published on 25 July 2016
Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain
artículo científico publicado en 2019
Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans
artículo científico publicado en 2011
Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
artículo científico publicado en 2009
Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit
artículo científico publicado en 2012
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
artículo científico publicado en 1998
Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia
artículo científico publicado en 1998
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
artículo científico publicado en 2015
Alpha-synuclein in familial Alzheimer disease: epitope mapping parallels dementia with Lewy bodies and Parkinson disease.
artículo científico publicado en 2001
Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae
artículo científico publicado en 2008
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
artículo científico publicado en 2018
Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons
scientific article published on 01 September 1996
Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease
artículo científico publicado en 2001
Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs
artículo científico publicado en 2016
Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2
artículo científico publicado en 2005
Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias
artículo científico publicado en 1993
Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice
artículo científico publicado en 2002
Alzheimer disease A68 proteins injected into rat brain induce codeposits of beta-amyloid, ubiquitin, and alpha 1-antichymotrypsin
artículo científico publicado en 1993
Alzheimer risk genes modulate the relationship between plasma apoE and cortical PiB binding
artículo científico publicado en 2015
Alzheimer's Disease Neuroimaging Initiative (ADNI): clinical characterization
artículo científico publicado en 2009
Alzheimer's disease biomarkers: walk with deliberate haste, don't run blithely on?
artículo científico publicado en 2013
Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects
artículo científico publicado en 2015
Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition
artículo científico publicado en 2009
Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease
artículo científico publicado en 2019
Alzheimer's disease, neuropeptides, neuropeptidase, and amyloid-beta peptide metabolism
artículo científico publicado en 2003
Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?
artículo científico publicado en 2018
Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.
artículo científico publicado en 2004
Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties.
artículo científico publicado en 2012
Aminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation
artículo científico publicado en 2013
Aminothienopyridazines as imaging probes of tau pathology: a patent evaluation of WO2013090497.
artículo científico publicado en 2014
Amygdaloid projections to prefrontal granular cortex in rhesus monkey demonstrated with horseradish peroxidase
artículo científico publicado el 12 de diciembre de 1975
Amyloid plaques in Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex contain species of A beta similar to those found in the amyloid plaques of Alzheimer's disease and pathological aging
artículo científico publicado en 1998
Amyloid plaques in cerebellar cortex and the integrity of Purkinje cell dendrites
artículo científico publicado en 1994
Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology
scientific article published on 20 November 2019
Amyloid-Beta Positron Emission Tomography Imaging of Alzheimer's Pathology in Parkinson's Disease Dementia
artículo científico publicado en 2016
Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas.
artículo científico publicado en 2003
Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation
artículo científico publicado en 2017
Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies
artículo científico publicado en 2010
Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases
scientific article published on 07 March 2009
Amyotrophic lateral sclerosis--a model of corticofugal axonal spread
artículo científico publicado en 2013
Amyotrophic lateral sclerosis-plus syndrome with TAR DNA-binding protein-43 pathology
artículo científico publicado en 2009
Amyotrophic lateral sclerosis/parkinsonism dementia complex: transgenic mice provide insights into mechanisms underlying a common tauopathy in an ethnic minority on Guam
artículo científico publicado en 2002
An Alzheimer's Disease-Derived Biomarker Signature Identifies Parkinson's Disease Patients with Dementia
artículo científico publicado en 2016
An English kindred with a novel recessive tauopathy and respiratory failure
artículo científico publicado en 2003
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline
scientific article published on 02 November 2020
An R5L tau mutation in a subject with a progressive supranuclear palsy phenotype
artículo científico publicado en 2002
An acetylation switch controls TDP-43 function and aggregation propensity
artículo científico
An extensive network of PHF tau-rich dystrophic neurites permeates neocortex and nearly all neuritic and diffuse amyloid plaques in Alzheimer disease
artículo científico publicado en 1994
An immunocytochemical study of normal and abnormal human cerebrospinal fluid with monoclonal antibodies to glial fibrillary acidic protein.
artículo científico publicado en 1986
An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice
artículo científico publicado en 2015
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease
artículo científico publicado en 2020
Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.
artículo científico publicado en 2016
Analysis of cerebrospinal fluid mitochondrial DNA levels in Alzheimer disease.
artículo científico publicado en 2014
Analysis of epitopes shared by Hirano bodies and neurofilament proteins in normal and Alzheimer's disease hippocampus
artículo científico publicado en 1989
Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies
scientific article published on 29 January 2020
Analytical and Clinical Performance of Amyloid-Beta Peptides Measurements in CSF of ADNIGO/2 Participants by an LC-MS/MS Reference Method
artículo científico publicado en 2020
Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration
artículo científico publicado en 2017
Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease
artículo científico publicado en 1999
Antibodies to the beta-amyloid peptide cross-react with conformational epitopes in human fibrinogen subunits from peripheral blood
artículo científico publicado en 1990
ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease
scientific article published on 04 January 2014
Apolipoprotein E epsilon 4 allele distribution in alcoholic dementia and in Alzheimer's disease in Japan.
artículo científico publicado en 1994
Areal and laminar distribution of some pulvinar cortical efferents in rhesus monkey
artículo científico publicado el 1 de octubre de 1976
Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint
scientific article published on 01 January 2020
Assessment of pathological tau proteins in frontotemporal dementias: qualitative and quantitative approaches
artículo científico publicado en 2004
Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease
artículo científico publicado en 2017
Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology
artículo científico publicado en 2011
Association of ABCA2 expression with determinants of Alzheimer's disease
artículo científico publicado en 2004
Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers
scientific article published on 03 July 2019
Association of CSF Aβ, amyloid PET and cognition in cognitively unimpaired elderly adults
scientific article published on 05 August 2020
Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease
artículo científico publicado en 1998
Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression
artículo científico publicado en 2015
Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders
scientific article published on 01 March 2019
Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease
artículo científico publicado en 2016
Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease
artículo científico publicado en 2013
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
artículo científico publicado en 1998
Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease
artículo científico publicado en 2013
Association of plasma and cortical amyloid beta is modulated by APOE ε4 status
scientific article published on 26 March 2013
Astrocyte senescence as a component of Alzheimer's disease
artículo científico publicado en 2012
Astrocytic TDP-43 pathology in Alexander disease
artículo científico publicado en 2014
Asymmetric bilateral demyelinating optic neuropathy from tacrolimus toxicity
artículo científico publicado en 2011
Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia
artículo científico publicado en 2017
At the interface of sensory and motor dysfunctions and Alzheimer's disease
artículo científico publicado en 2014
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
artículo científico publicado en 2010
Atypical Alzheimer's disease in an elderly United States resident with amyotrophic lateral sclerosis and pathological tau in spinal motor neurons
artículo científico publicado en 2014
Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease
artículo científico publicado en 2020
Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
scientific article published on 01 September 2019
Author response.
artículo científico publicado en 2013
Autopsy: Cutting Away the Myths
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artículo científico publicado el 1 de junio de 1992
Autosomal dominant dementia with widespread neurofibrillary tangles.
artículo científico publicado en 1997
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein
artículo científico publicado en 1999
Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies.
artículo científico publicado en 2005
Axonal transport defects: a common theme in neurodegenerative diseases
artículo científico publicado en 2005
A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model
artículo científico publicado en 2010
BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo
artículo científico publicado en 2005
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate.
artículo científico publicado en 2011
Behavioral variant frontotemporal dementia with corticobasal degeneration pathology: phenotypic comparison to bvFTD with Pick's disease
artículo científico publicado en 2011
Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression
artículo científico publicado en 2006
Bilateral subthalamic nucleus deep brain stimulation for advanced PD: Correlation of intraoperative MER and postoperative MRI with neuropathological findings
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artículo científico publicado el 1 de septiembre de 2003
Biochemical analysis of tau proteins in argyrophilic grain disease, Alzheimer's disease, and Pick's disease : a comparative study
artículo científico publicado en 2002
Biochemical and pathological characterization of Lrrk2.
artículo científico publicado en 2006
Biochemical and pathological characterization of frontotemporal dementia due to a Leu266Val mutation in microtubule-associated protein tau in an African American individual
artículo científico publicado en 2006
Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease
artículo científico publicado en 2003
Biological markers of amyloid beta-related mechanisms in Alzheimer's disease
artículo científico publicado en 2010
Biomarker Based Diagnosis Of Very Mild Alzheimer'S Disease: A Multicenter Study
article
Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease
artículo científico publicado en 2010
Biomarkers in frontotemporal lobar degenerations--progress and challenges
artículo científico publicado en 2011
Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics
artículo científico publicado en 2007
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.
artículo científico publicado en 1994
Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease
artículo científico publicado en 2011
Brain MR: pathologic correlation with gross and histopathology. 1. Lacunar infarction and Virchow-Robin spaces
artículo científico publicado en 1988
Brain MR: pathologic correlation with gross and histopathology. 2. Hyperintense white-matter foci in the elderly
artículo científico publicado en 1988
Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia
scientific article published on 14 April 2020
Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures
artículo científico publicado en 2015
Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease
artículo científico publicado en 2010
Brain degeneration linked to "fatal attractions" of proteins in Alzheimer's disease and related disorders
artículo científico publicado en 2001
Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis
artículo científico publicado en 2004
Brain progranulin expression in GRN-associated frontotemporal lobar degeneration
artículo científico publicado en 2009
Brain trauma in aged transgenic mice induces regression of established abeta deposits
artículo científico publicado en 2000
Brain-penetrant tetrahydronaphthalene thromboxane A2-prostanoid (TP) receptor antagonists as prototype therapeutics for Alzheimer's disease
artículo científico publicado en 2012
Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer's disease and related tauopathies
artículo científico publicado en 2014
Building a roadmap for developing combination therapies for Alzheimer's disease
artículo científico publicado en 2015
Building an integrated neurodegenerative disease database at an academic health center
artículo científico publicado en 2011
Burden of neurodegenerative diseases in a cohort of medical examiner subjects
artículo científico publicado en 2010
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy
scientific article published on 20 July 2019
C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts
scientific article published on 17 September 2020
COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)
artículo científico publicado en 2021
CSF Apo-E levels associate with cognitive decline and MRI changes
artículo científico publicado en 2014
CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease?
artículo científico publicado en 2014
CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects
artículo científico publicado en 2011
CSF biomarker variability in the Alzheimer's Association quality control program
artículo científico publicado en 2013
CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study
artículo científico publicado en 2016
CSF biomarkers cutoffs: the importance of coincident neuropathological diseases
artículo científico publicado en 2012
CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts
artículo científico publicado en 2018
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline
scholarly article by Marc Suárez-Calvet et al published December 2018 in EMBO Molecular Medicine
CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.
artículo científico publicado en 2018
CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer's disease
artículo científico publicado en 2013
Calcineurin immunoreactivity in Alzheimer's disease
artículo científico publicado en 1994
Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons
artículo científico publicado en 2016
Cardiovascular risk factors, cortisol, and amyloid-β deposition in Alzheimer's Disease Neuroimaging Initiative
artículo científico publicado en 2012
Caregiver report of apathy predicts dementia in Parkinson's disease
artículo científico publicado en 2015
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease
artículo científico publicado en 2008
Cell-to-Cell Transmission of Tau and α-Synuclein
artículo científico publicado en 2020
Cellular and molecular neuropathology of the olfactory epithelium and central olfactory pathways in Alzheimer's disease and schizophrenia
artículo científico publicado en 1998
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
artículo científico publicado en 2018
Cerebellar dysplasias in humans: development and possible relationship to glial and primitive neuroectodermal tumors of the cerebellar vermis
artículo científico publicado en 1994
Cerebral ischemia and CNS transplantation: differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line
artículo científico publicado en 1998
Cerebrospinal Fluid Total and Phosphorylated α-Synuclein in Patients with Creutzfeldt-Jakob Disease and Synucleinopathy
scientific article published on 22 August 2018
Cerebrospinal fluid abnormalities and rate of decline in everyday function across the dementia spectrum: normal aging, mild cognitive impairment, and Alzheimer disease
artículo científico publicado en 2010
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry
artículo científico publicado en 2017
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
artículo científico publicado en 2009
Cerebrospinal fluid biomarkers for differentiation of frontotemporal lobar degeneration from Alzheimer's disease
artículo científico publicado en 2013
Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals
artículo científico publicado en 2014
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology
artículo científico publicado en 2018
Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer's disease
artículo científico publicado en 2015
Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease
artículo científico publicado en 2005
Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment
artículo científico publicado en 2011
Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?
artículo científico publicado en 2003
Cerebrospinal fluid tau protein as a potential diagnostic marker in Alzheimer's disease
artículo científico publicado en 1998
Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration
article
Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.
artículo científico publicado en 2018
Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias
artículo científico publicado en 2012
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
artículo científico publicado en 2001
Characterization and differential distribution of the three major human protein kinase C isozymes (PKC alpha, PKC beta, and PKC gamma) of the central nervous system in normal and Alzheimer's disease brains.
artículo científico publicado en 1991
Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease
artículo científico publicado en 2006
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies
artículo científico publicado en 2016
Characterization of Parkinson's disease using blood-based biomarkers: A multicohort proteomic analysis
artículo científico publicado en 2019
Characterization of hippocampal subfields using ex vivo MRI and histology data: Lessons for in vivo segmentation
scientific article published on 01 November 2019
Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease
artículo científico publicado en 2019
Characterization of tau binding by gosuranemab
scientific article published on 26 September 2020
Characterization of tau fibrillization in vitro
artículo científico publicado en 2010
Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex
artículo científico publicado en 2006
Characterization of unmyelinated axons uniting epidermal and dermal immune cells in primate and murine skin
artículo científico publicado en 1998
Characterizing Alzheimer's disease using a hypometabolic convergence index
artículo científico publicado en 2011
Characterizing the human hippocampus in aging and Alzheimer's disease using a computational atlas derived from ex vivo MRI and histology.
artículo científico publicado en 2018
Chemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy
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artículo científico publicado el 1 de agosto de 1995
Cholera toxin and wheat germ agglutinin conjugates as neuroanatomical probes: Their uptake and clearance, transganglionic and retrograde transport and sensitivity
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artículo científico publicado el 15 de julio de 1982
Chondroid chordoma: a low-grade chondrosarcoma and its differential diagnosis
artículo científico publicado en 1989
Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies.
artículo científico publicado en 2005
Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy
artículo científico publicado en 2011
Chronic traumatic encephalopathy - confusion and controversies
scientific article published on 01 March 2019
Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players
scientific article published on 01 June 2019
Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases
artículo científico publicado en 2017
Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau
artículo científico publicado en 2020
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein.
artículo científico publicado en 2005
Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans
artículo científico publicado en 2010
Clinical and Dopamine Transporter Imaging Characteristics of Leucine- Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study
scientific article published on 19 February 2020
Clinical and biochemical differences in patients having Parkinson disease with vs without GBA mutations.
artículo científico publicado en 2013
Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study
artículo científico publicado en 2019
Clinical and multimodal biomarker correlates of ADNI neuropathological findings
artículo científico publicado en 2013
Clinical and pathological continuum of multisystem TDP-43 proteinopathies
artículo científico publicado en 2009
Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration
artículo científico publicado en 2020
Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease
artículo científico publicado en 2015
Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia
artículo científico
Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations.
artículo científico publicado en 2007
Clinical, neuroimaging, and pathologic features of progressive nonfluent aphasia
artículo científico publicado en 1996
Clinically silent Alzheimer's and vascular pathologies influence brain networks supporting executive function in healthy older adults.
artículo científico publicado en 2017
Clinicopathological Study of Patients With C9ORF72-Associated Frontotemporal Dementia Presenting With Delusions
artículo científico publicado en 2014
Clinicopathological correlations in behavioural variant frontotemporal dementia.
artículo científico publicado en 2017
Clinicopathological correlations in corticobasal degeneration
artículo científico publicado en 2011
Clonal human (hNT) neuron grafts for stroke therapy: neuropathology in a patient 27 months after implantation
artículo científico publicado en 2002
Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases
artículo científico publicado en 2007
Co-occurrence of Parkinson's disease with progressive supranuclear palsy
artículo científico publicado en 2002
Cognitive Functional Abilities in Parkinson's Disease: Agreement Between Patients and Informants
scientific article published on 17 May 2019
Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders
artículo científico publicado en 2019
Cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology
artículo científico publicado en 2012
Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis
artículo científico publicado en 2012
Cognitive impairment in elderly schizophrenia: a dementia (still) lacking distinctive histopathology
artículo científico
Cognitive profile of LRRK2-related Parkinson's disease
artículo científico publicado en 2015
Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition
artículo científico publicado en 2011
Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence
artículo científico publicado en 2016
Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease
artículo científico publicado en 1998
Commentary on "Diagnosis of Alzheimer's disease: two decades of progress". Alzheimer's disease research: new opportunities for early diagnosis and drug discovery
artículo científico publicado en 2005
Commentary on "Optimal design of clinical trials for drugs designed to slow the course of Alzheimer's disease." Biochemical biomarkers of late-life dementia
artículo científico publicado en 2006
Common neuropathological features underlie distinct clinical presentations in three siblings with hereditary diffuse leukoencephalopathy with spheroids caused by CSF1R p.Arg782His
artículo científico publicado en 2015
Common threads in neurodegenerative disorders of aging
Common variant rs356182 near SNCA defines a Parkinson's disease endophenotype
artículo científico publicado en 2016
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
artículo científico publicado en 2010
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
artículo científico publicado en 2011
Comparative epitope analysis of neuronal cytoskeletal proteins in Alzheimer's disease senile plaque neurites and neuropil threads.
artículo científico publicado en 1991
Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases
scientific article published on December 2013
Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging
artículo científico publicado en 2013
Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid
artículo científico publicado en 2013
Comparing predictors of conversion and decline in mild cognitive impairment
artículo científico publicado en 2010
Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology
artículo científico publicado en 2011
Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms
artículo científico publicado en 2012
Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort
scientific article published on 01 January 2020
Comparison of xMAP and ELISA assays for detecting cerebrospinal fluid biomarkers of Alzheimer's disease
artículo científico publicado en 2012
Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays
artículo científico publicado en 2020
Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factor
artículo científico publicado en 2021
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies
artículo científico publicado en 2008
Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred
artículo científico publicado en 2002
Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease
artículo científico publicado en 2020
Conjugates of horseradish peroxidase (HRP) with cholera toxin and wheat germ agglutinin are superior to free HRP as orthogradely transported markers
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artículo científico publicado el 2 de noviembre de 1981
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre
scientific article published on 10 July 2013
Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease
artículo científico publicado en 2020
Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders
artículo científico publicado en 1996
Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies
artículo científico publicado en 2006
Converging Patterns of α-Synuclein Pathology in Multiple System Atrophy
artículo científico publicado en 2018
Conversion between mini-mental state examination, montreal cognitive assessment, and dementia rating scale-2 scores in Parkinson's disease
artículo científico publicado en 2014
Coordinate reduction in cell proliferation and cell death in mouse olfactory epithelium from birth to maturity
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artículo científico publicado el 4 de julio de 1997
Correction of microtubule defects within Aβ plaque-associated dystrophic axons results in lowered Aβ release and plaque deposition
scientific article published on 11 September 2020
Correlating Cognitive Decline with White Matter Lesion and Brain Atrophy Magnetic Resonance Imaging Measurements in Alzheimer's Disease
artículo científico publicado en 2015
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature
artículo científico publicado en 2012
Corticothalamic neurons and thalamocortical terminal fields: An investigation in rat using horseradish peroxidase and autoradiography
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artículo científico publicado el 7 de marzo de 1975
Current state of Alzheimer's fluid biomarkers
scholarly article by José Luis Molinuevo et al published 1 December 2018 in Acta Neuropathologica
Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists
artículo científico publicado en 2011
Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery.
artículo científico publicado en 2006
Cytoskeletal requirements in axonal transport of slow component-b
artículo científico publicado en 2008
D2-40, a novel monoclonal antibody against the M2A antigen as a marker to distinguish hemangioblastomas from renal cell carcinomas
artículo científico publicado en 2005
DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia
artículo científico publicado en 2004
Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis
artículo científico publicado en 2013
Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders
artículo científico publicado en 2016
Deep clinical and neuropathological phenotyping of Pick disease
artículo científico publicado en 2015
Defining and predicting transdiagnostic categories of neurodegenerative disease
artículo científico publicado en 2020
Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum
artículo científico publicado en 2020
Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons
scientific journal article
Delayed transplantation of human neurons following brain injury in rats: a long-term graft survival and behavior study
artículo científico publicado en 2005
Dementia: a word to be forgotten.
artículo científico publicado en 2008
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
artículo científico publicado en 2012
Derivation of cutoffs for the Elecsys® amyloid β (1–42) assay in Alzheimer's disease
artículo científico publicado en 2018
Design of comprehensive Alzheimer's disease centers to address unmet national needs
artículo científico publicado en 2010
Design, synthesis and evaluation of photoactivatable derivatives of microtubule (MT)-active [1,2,4]triazolo[1,5-a]pyrimidines
scientific article published on 05 May 2018
Detection of Alzheimer Disease (AD)-Specific Tau Pathology in AD and NonAD Tauopathies by Immunohistochemistry With Novel Conformation-Selective Tau Antibodies.
artículo científico publicado en 2018
Detection of Alzheimer Disease Pathology in Patients Using Biochemical Biomarkers: Prospects and Challenges for Use in Clinical Practice
scientific article published on 17 December 2019
Detection of Alzheimer's disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau)
Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau
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artículo científico publicado el 11 de agosto de 1995
Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients
artículo científico publicado en 2003
Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.
artículo científico publicado en 2010
Development and in vitro characterization of a cationized monoclonal antibody against beta A4 protein: a potential probe for Alzheimer's disease
artículo científico publicado en 1994
Development and initial testing of the Penn Parkinson's Daily Activities Questionnaire
artículo científico publicado en 2015
Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease
artículo científico publicado en 2016
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium
artículo científico publicado en 2017
Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people
artículo científico publicado en 2010
Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease
artículo científico publicado en 2014
Diagnostic effectiveness of quantitative [¹⁸F]flutemetamol PET imaging for detection of fibrillar amyloid β using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus
artículo científico publicado en 2014
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative
artículo científico publicado en 2020
Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra
artículo científico publicado en 2001
Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brains
artículo científico publicado en 2014
Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts
artículo científico publicado en 1991
Diffusion Tensor MRI to Distinguish Progressive Supranuclear Palsy from α-Synucleinopathies
scientific article published on 15 October 2019
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody
artículo científico publicado en 2020
Discovery of brain-penetrant, orally bioavailable aminothienopyridazine inhibitors of tau aggregation
artículo científico publicado en 2010
Disruption of large-scale neural networks in non-fluent/agrammatic variant primary progressive aphasia associated with frontotemporal degeneration pathology
artículo científico publicado en 2012
Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells
artículo científico publicado en 2000
Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions
artículo científico publicado en 2012
Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1 - 42 and Hypertension
artículo científico publicado en 2018
Distinct antemortem profiles in patients with pathologically defined frontotemporal dementia.
artículo científico publicado en 2007
Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies.
artículo científico publicado en 2017
Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro
artículo científico publicado en 2003
Distinct α-synuclein strains differentially promote tau inclusions in neurons
artículo científico publicado en 2013
Distribution patterns of tau pathology in progressive supranuclear palsy
artículo científico publicado en 2020
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
artículo científico publicado en 2008
Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia
artículo científico publicado en 2019
Domain structure of neurofilament subunits as revealed by monoclonal antibodies.
artículo científico publicado en 1985
Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
artículo científico publicado en 2008
Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases
artículo científico publicado en 2015
Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies
artículo científico publicado en 2019
Drug discovery in neurodegenerative diseases
scientific article published on 09 February 2005
Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia
scientific article published on May 2004
Dysregulation of olfactory receptor neuron lineage in schizophrenia
artículo científico publicado en 2001
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
artículo científico publicado en 2011
Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.
artículo científico publicado en 2018
Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy
artículo científico publicado en 2020
Early fetal acquisition of the chromaffin and neuronal immunophenotype by human adrenal medullary cells. An immunohistological study using monoclonal antibodies to chromogranin A, synaptophysin, tyrosine hydroxylase, and neuronal cytoskeletal protei
artículo científico publicado en 1990
Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology
artículo científico publicado en 2019
Early marker for Alzheimer's disease: hippocampus T1rho (T(1rho)) estimation
artículo científico publicado en 2009
Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease
artículo científico publicado en 2003
Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration
artículo científico publicado en 2018
Editorial on Consensus Recommendations for the Postmortem Diagnosis of Alzheimer Disease from the National Institute on Aging and the Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer Disease
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artículo científico publicado el 1 de octubre de 1997
Effect of Genetic Risk Factors and Disease Progression on the Cerebrospinal Fluid Tau Levels in Alzheimer's Disease
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artículo científico publicado el 1 de octubre de 1997
Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease
artículo científico publicado en 2010
Effects of alpha-tocopherol on an animal model of tauopathies
artículo científico publicado en 2004
Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults
artículo científico publicado en 2013
Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease
artículo científico publicado en 2009
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study
artículo científico publicado en 2014
Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer's disease in veterans, using the Alzheimer's Disease Neuroimaging Initiative
artículo científico publicado en 2014
Elderly patients with schizophrenia exhibit infrequent neurodegenerative lesions
artículo científico publicado en 1994
Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology
artículo científico publicado en 2018
Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD
article
Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment
artículo científico publicado en 2005
Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease
artículo científico publicado en 2019
Emerging β-amyloid pathology and accelerated cortical atrophy
artículo científico publicado en 2014
Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration
artículo científico publicado en 2019
Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient
scientific article published on 29 January 2008
Endoscopic human olfactory biopsy technique: a preliminary report
scientific article published on 01 July 1993
Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats
artículo científico publicado en 1998
Enhanced neurofibrillary tangle formation, cerebral atrophy, and cognitive deficits induced by repetitive mild brain injury in a transgenic tauopathy mouse model
artículo científico publicado en 2005
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis
artículo científico publicado en 2008
Epitope analysis of senile plaque components in the hippocampus of patients with Parkinson's disease
artículo científico publicado el 1 de julio de 1992
Epitopes located in spatially separate domains of each neurofilament subunit are present in parkinson's disease lewy bodies
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artículo científico publicado el 1 de julio de 1991
Epitopes that span the tau molecule are shared with paired helical filaments.
artículo científico publicado en 1988
Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy
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artículo científico publicado el 13 de octubre de 2010
Erratum to: Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)
artículo científico publicado en 2015
Establishment and characterization of the human medulloblastoma cell line and transplantable xenograft D283 Med.
artículo científico publicado en 1985
Establishment of a cell model of ALS disease: Golgi apparatus disruption occurs independently from apoptosis
artículo científico publicado en 2007
Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases.
artículo científico publicado en 2017
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
artículo científico publicado en 2012
Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group
artículo científico publicado en 2017
Evaluation of potential infectivity of Alzheimer and Parkinson disease proteins in recipients of cadaver-derived human growth hormone
artículo científico publicado en 2013
Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies
artículo científico publicado en 2021
Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy
artículo científico publicado en 2016
Evaluation of the cyclopentane-1,2-dione as a potential bio-isostere of the carboxylic acid functional group
artículo científico publicado en 2014
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases
artículo científico publicado en 2012
Evidence for ordering of Alzheimer disease biomarkers
artículo científico publicado en 2011
Evidence of a founder effect in families with frontotemporal dementia that harbor the tau +16 splice mutation
artículo científico publicado en 2004
Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis
artículo científico publicado en 2008
Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments
scientific article published on August 2008
Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease
artículo científico publicado en 2020
Ex vivo gene therapy using targeted engraftment of NGF-expressing human NT2N neurons attenuates cognitive deficits following traumatic brain injury in mice
artículo científico publicado en 2004
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study
artículo científico publicado en 2020
Exercise and cognition: results from the National Long Term Care Survey
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artículo científico publicado el 1 de noviembre de 2010
Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
artículo científico publicado en 2009
Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death
artículo científico publicado en 2011
Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
artículo científico publicado en 2015
Exome sequencing reveals VCP mutations as a cause of familial ALS
artículo científico publicado en 2010
Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration
artículo científico publicado en 2017
Exploring human/animal intersections: converging lines of evidence in comparative models of aging
artículo científico publicado en 2007
Expression of GDNF mRNA in rat and human nervous tissue
artículo científico publicado en 1994
Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies
artículo científico publicado en 2009
Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain
artículo científico publicado en 2013
Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas
artículo científico publicado en 2003
Expression of beta-amyloid precursor protein in the developing human spinal cord
artículo científico publicado en 1994
Expression of neurofilament and neuron-specific enolase in small cell tumors of skin using immunohistochemistry
artículo científico publicado en 1985
Expression of neurofilament antigens by normal and neoplastic human adrenal chromaffin cells
scientific article published on 01 July 1985
Expression of neuronal and glial polypeptides during histogenesis of the human cerebellar cortex including observations on the dentate nucleus
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artículo científico publicado el 15 de agosto de 1993
Expression of the small heat-shock protein alphaB-crystallin in tauopathies with glial pathology
artículo científico publicado en 2004
Expression of trk receptors in the developing and adult human central and peripheral nervous system
artículo científico publicado en 1995
Expression patterns of beta-amyloid precursor protein (beta-APP) in neural and nonneural human tissues from Alzheimer's disease and control subjects
artículo científico publicado en 1991
Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons
artículo científico publicado en 2000
Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions
artículo científico publicado en 2010
FASTKD2 is associated with memory and hippocampal structure in older adults
artículo científico publicado en 2014
FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression
artículo científico publicado en 2009
FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration
artículo científico publicado en 2010
Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI
artículo científico publicado en 2011
Familial Frontotemporal Dementia: From Gene Discovery to Clinical Molecular Diagnostics
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artículo científico publicado el 1 de octubre de 2003
Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia
artículo científico publicado en 1998
Features of Patients With Nonfluent/Agrammatic Primary Progressive Aphasia With Underlying Progressive Supranuclear Palsy Pathology or Corticobasal Degeneration
artículo científico publicado en 2016
Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation
artículo científico publicado en 2004
Forebrain overexpression of alpha-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption
artículo científico publicado en 2009
Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia
artículo científico publicado en 2013
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
artículo científico publicado en 2012
Frontotemporal dementia and its subtypes: a genome-wide association study
artículo científico publicado en 2014
Frontotemporal dementia and tauopathy
artículo científico publicado en 2001
Frontotemporal dementia with novel tau pathology and a Glu342Val tau mutation
artículo científico publicado en 2000
Frontotemporal dementia with novel tau pathology and a Glu342Valtau mutation
scholarly article by Carol F. Lippa et al published December 2000 in Annals of Neurology
Frontotemporal dementia: clinicopathological correlations
artículo científico publicado en 2006
Frontotemporal dementia: report of a familial case
artículo científico publicado en 2001
Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine
artículo científico publicado en 2014
Full-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques.
artículo científico publicado en 1996
Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
scientific article published on 22 July 2015
GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease
artículo científico publicado en 2015
GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology
artículo científico publicado en 2012
GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.
artículo científico publicado en 2017
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease
artículo científico publicado en 2013
Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
artículo científico publicado en 2011
Gene expression changes in the course of normal brain aging are sexually dimorphic
artículo científico publicado en 2008
Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex
artículo científico publicado en 2002
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration
artículo científico publicado en 2011
Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration.
artículo científico publicado en 2013
Genetic evidence for the involvement of tau in progressive supranuclear palsy
artículo científico publicado en 1997
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
artículo científico publicado en 2019
Genetic predictors of survival in behavioral variant frontotemporal degeneration
scientific article published on 19 September 2019
Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases
artículo científico publicado en 2020
Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease
artículo científico publicado en 2005
Genetically Modified NT2N Human Neuronal Cells Mediate Long-Term Gene Expression as CNS Grafts In Vivo and Improve Functional Cognitive Outcome Following Experimental Traumatic Brain Injury
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artículo científico publicado el 1 de abril de 2003
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
artículo científico publicado en 2021
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.
artículo científico publicado en 2018
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD
scientific article published on 09 February 2019
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
artículo científico publicado en 2016
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias
artículo científico publicado en 2014
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers
artículo científico publicado en 2017
Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy
artículo científico publicado en 2015
Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism
artículo científico publicado en 2016
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.
artículo científico publicado en 1998
Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumors
artículo científico publicado en 1996
Global democratic consensus on neuropathological disease criteria
artículo científico publicado en 2002
Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult
scientific article published on 30 December 2019
Glucose hypometabolism and neuropathological correlates in brains of dementia with Lewy bodies.
artículo científico publicado en 2000
Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research
artículo científico publicado en 2015
Hallucinations and Development of Dementia in Parkinson's Disease
artículo científico publicado en 2020
Harnessing neuroplasticity for clinical applications
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artículo científico publicado en 2011
Healthy brain aging: a meeting report from the Sylvan M. Cohen Annual Retreat of the University of Pennsylvania Institute on Aging
artículo científico publicado en 2008
Heritability and genetic variance of dementia with Lewy bodies
scientific article published on 03 April 2019
Heterogeneity of neuroanatomical patterns in prodromal Alzheimer's disease: links to cognition, progression and biomarkers.
artículo científico publicado en 2016
High Throughput Screening for Small Molecule Inhibitors of Heparin-induced Tau Fibril Formation
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artículo científico publicado el 25 de marzo de 2011
High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration
artículo científico publicado en 2015
High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation
artículo científico publicado en 2007
High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies
scientific article published on 16 October 2020
High-throughput quantitative histological analysis of Alzheimer's disease pathology using a confocal digital microscanner
artículo científico publicado en 1999
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation
artículo científico publicado en 2020
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration
artículo científico publicado en 2020
Hippocampal Subfield Pathologic Burden in Lewy Body Diseases versus Alzheimer's Disease
artículo científico publicado en 2020
History of cigarette smoking in cognitively-normal elders is associated with elevated cerebrospinal fluid biomarkers of oxidative stress
artículo científico publicado en 2014
Horseradish peroxidase (HRP) conjugates of cholera toxin and lectins are more sensitive retrogradely transported markers than free HRP
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artículo científico publicado el 7 de enero de 1982
Human fetal hippocampal development: I. Cytoarchitecture, myeloarchitecture, and neuronal morphologic features
artículo científico publicado en 1996
Human fetal hippocampal development: II. The neuronal cytoskeleton
artículo científico publicado en 1996
Human neurons that constitutively secrete A beta do not induce Alzheimer's disease pathology following transplantation and long-term survival in the rodent brain
artículo científico publicado en 1995
Human olfactory epithelium in normal aging, alzheimer's disease, and other neurodegenerative disorders
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artículo científico publicado el 15 de agosto de 1991
Human tau pathology transmits glial tau aggregates in the absence of neuronal tau
scientific article published on 01 February 2020
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation
scientific article published on 04 July 2019
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
artículo científico publicado en 2010
IBOX(2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain
artículo científico publicado en 2001
IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques
artículo científico publicado en 2002
Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening
artículo científico publicado en 2009
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
article
Identification of phosphorylation sites in PHF-TAU from patients with Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex.
artículo científico publicado en 1996
Identifying Neuroimaging and Proteomic Biomarkers for MCI and AD via the Elastic Net
article
Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study
artículo científico publicado en 2015
Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies
artículo científico publicado en 2008
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls
artículo científico publicado en 2013
Immunochemical detection of diverse molecular species of horseradish peroxidase recovered from rat superior cervical ganglion following retrograde transport
artículo científico publicado en 1985
Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy
artículo científico publicado en 2000
Immunohistochemical demonstration of phosphorylated and nonphosphorylated forms of human neurofilament subunits in human pulmonary carcinoids
artículo científico publicado en 1987
Immunohistochemical detection of the effects of toxic injury on the central nervous system
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artículo científico publicado el 1 de febrero de 1995
Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration.
artículo científico publicado en 1997
Impact of Pre-Analytical Differences on Biomarkers in the ADNI and PPMI Studies: Implications in the Era of Classifying Disease Based on Biomarkers
artículo científico publicado en 2019
Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples
artículo científico publicado en 2019
Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014
artículo científico publicado en 2015
Impaired glutamate transport in a mouse model of tau pathology in astrocytes.
artículo científico publicado en 2006
Impaired rapid eye movement sleep in the Tg2576 APP murine model of Alzheimer's disease with injury to pedunculopontine cholinergic neurons
artículo científico publicado en 2005
Improved protocol for measurement of plasma β-amyloid in longitudinal evaluation of Alzheimer's Disease Neuroimaging Initiative study patients
artículo científico publicado en 2012
Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury
artículo científico publicado en 1997
In VivoPositron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders
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artículo científico publicado el 23 de marzo de 2011
In pursuit of the molecular neuropathology of schizophrenia
artículo científico publicado en 1995
In situ blood-brain barrier permeability of a C-10 paclitaxel carbamate
artículo científico publicado en 2008
In vivo measurement of plaque burden in a mouse model of Alzheimer's disease
artículo científico publicado en 2006
In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology
artículo científico publicado en 2013
Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease
artículo científico publicado en 2002
Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity
artículo científico publicado en 2000
Increased levels of fucosyltransferase IX and carbohydrate Lewis(x) adhesion determinant in human NT2N neurons.
artículo científico publicado en 2007
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease
scientific article published on 01 August 2019
Increased vulnerability of NFH-LacZ transgenic mouse to traumatic brain injury-induced behavioral deficits and cortical damage
artículo científico publicado en 1999
Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease
artículo científico publicado en 2014
Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration
artículo científico publicado en 2020
Induction of neurofilament triplet proteins in PC12 cells by nerve growth factor
artículo científico publicado en 1982
Inflammation and white matter degeneration persist for years after a single traumatic brain injury
artículo científico publicado en 2013
Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel
artículo científico publicado en 2013
Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau.
artículo científico publicado en 2009
Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein
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artículo científico publicado el 25 de abril de 2003
Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo
artículo científico publicado en 2020
Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers
artículo científico publicado en 2013
Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease
artículo científico publicado en 2016
Interactions between Hsp70 and the hydrophobic core of alpha-synuclein inhibit fibril assembly
scientific journal article
Interactions of Amyloidogenic Proteins
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artículo científico publicado el 1 de enero de 2003
Interneuronal transfer of axonally transported proteins: studies with HRP and HRP conjugates of wheat germ agglutinin, cholera toxin and the B subunit of cholera toxin
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artículo científico publicado el 8 de octubre de 1984
Internexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturity
artículo científico publicado en 1997
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
artículo científico publicado en 2014
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
artículo científico publicado en 2012
Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration
artículo científico publicado en 2011
Intraneuronal and extracellular neurofibrillary tangles exhibit mutually exclusive cytoskeletal antigens
scientific article published on 01 February 1988
Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes
scientific article published on 01 November 2019
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
artículo científico publicado en 2015
Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation
artículo científico publicado en 1990
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study
artículo científico publicado en 2017
Iodinated tracers for imaging amyloid plaques in the brain
artículo científico publicado en 2003
Is multiple system atrophy an infectious disease?
artículo científico publicado en 2018
Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain
artículo científico publicado en 2001
LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons.
artículo científico publicado en 2018
LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice
artículo científico publicado en 2019
Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology
artículo científico publicado en 2010
Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease
artículo científico
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
artículo científico publicado en 2020
Leptomeningeal carcinomatosis presenting as eosinophilic meningitis
artículo científico publicado en 1986
Lewy bodies contain beta-amyloid precursor proteins of Alzheimer's disease
artículo científico publicado el 10 de julio de 1992
Lewy bodies in the amygdala: increase of alpha-synuclein aggregates in neurodegenerative diseases with tau-based inclusions
artículo científico publicado en 2004
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.
artículo científico publicado en 2019
Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration
scientific article published on 24 August 2020
Living Longer and Paying the Price?
artículo científico publicado en 2005
Localization of the mitogen activated protein kinase ERK2 in Alzheimer's disease neurofibrillary tangles and senile plaque neurites
artículo científico publicado en 1993
Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma
artículo científico publicado en 2004
Long-term deep brain stimulation in a patient with essential tremor: clinical response and postmortem correlation with stimulator termination sites in ventral thalamus. Case report
artículo científico publicado en 2000
Long-term integration and neuronal differentiation of human embryonal carcinoma cells (NTera-2) transplanted into the caudoputamen of nude mice
artículo científico publicado en 1996
Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls.
artículo científico publicado en 2017
Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease
scientific article published on 30 July 2019
Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI
scientific article published on 29 June 2013
Longitudinal change of biomarkers in cognitive decline
artículo científico publicado en 2011
Longitudinal change of clinical and biological measures in early Parkinson's disease: Parkinson's progression markers initiative cohort.
artículo científico publicado en 2018
Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease
artículo científico publicado en 2012
Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer's disease
artículo científico publicado en 2019
Longitudinal study of normal cognition in Parkinson disease
artículo científico publicado en 2015
Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia
artículo científico publicado en 2001
Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis
artículo científico publicado en 2010
Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment
artículo científico publicado en 2014
Low plasma ApoE levels are associated with smaller hippocampal size in the Alzheimer's disease neuroimaging initiative cohort
artículo científico publicado en 2014
Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential
artículo científico publicado en 2014
Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype
artículo científico publicado en 2014
Lowering the risk of Alzheimer's disease: evidence-based practices emerge from new research
artículo científico publicado en 2005
MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations
scientific article published on July 2009
MRI and CSF biomarkers in normal, MCI, and AD subjects: predicting future clinical change
artículo científico publicado en 2009
MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers
artículo científico publicado en 2009
MT-Stabilizer, Dictyostatin, Exhibits Prolonged Brain Retention and Activity: Potential Therapeutic Implications
artículo científico publicado en 2013
Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis
artículo científico publicado en 2020
Malignant pineocytoma with prominent papillary features
artículo científico publicado en 1982
Many roads to Parkinson's disease neurodegeneration: head trauma-a road more traveled than we know?
artículo científico publicado en 2013
Mapping correlations between ventricular expansion and CSF amyloid and tau biomarkers in 240 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls
artículo científico publicado en 2009
Measurements of auto-antibodies to α-synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease.
artículo científico publicado en 2018
Mechanisms of Cell-to-Cell Transmission of Pathological Tau: A Review
Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery
artículo científico publicado en 2006
Medial pulvinar afferents to frontal eye fields in rhesus monkey demonstrated by horseradish peroxidase
artículo científico publicado en 1974
Meeting summary--cell biology of Parkinson's disease and related neurodegenerative disorders
artículo científico publicado en 2003
Memory, executive, and multidomain subtle cognitive impairment: clinical and biomarker findings
artículo científico publicado en 2015
Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis
artículo científico publicado en 2005
Metabolic network failures in Alzheimer's disease: A biochemical road map.
artículo científico publicado en 2017
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.
artículo científico publicado en 2018
Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis
artículo científico publicado en 2012
Microglial activation correlates with disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosis
artículo científico publicado en 2012
Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies
artículo científico publicado en 2012
Microtubule stabilizing drugs for the treatment of Alzheimer's disease
artículo científico publicado en 1994
Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model
artículo científico publicado en 2004
Microtubule-stabilising drugs for therapy of Alzheimer's disease and other neurodegenerative disorders with axonal transport impairments
artículo científico publicado en 2005
Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease
artículo científico publicado en 2014
Mild head injury increasing the brain's vulnerability to a second concussive impact
artículo científico publicado en 2001
Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in cellular Bcl-2 immunoreactivity
artículo científico publicado en 2002
Milder Alzheimer's disease pathology in heart failure and atrial fibrillation
artículo científico publicado en 2017
Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies
artículo científico publicado en 2002
Modeling Parkinson's disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
artículo científico publicado en 2017
Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease
artículo científico publicado en 2004
Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity
artículo científico publicado en 2016
Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease
artículo científico publicado en 1996
Molecular identification of AMY, an Alzheimer disease amyloid-associated protein
artículo científico publicado en 2003
Molecular markers of primitive neuroectodermal tumors and other pediatric central nervous system tumors. Monoclonal antibodies to neuronal and glial antigens distinguish subsets of primitive neuroectodermal tumors.
artículo científico publicado en 1989
Molecular milestones that signal axonal maturation and the commitment of human spinal cord precursor cells to the neuronal or glial phenotype in development
artículo científico publicado en 1991
Molecular phenotype of simian virus 40 large T antigen-induced primitive neuroectodermal tumors in four different lines of transgenic mice
scientific journal article
Monoclonal and polyclonal antibodies against neural antigens: diagnostic applications for studies of central and peripheral nervous system tumors
artículo científico publicado en 1983
Monoclonal antibodies to purified cortical Lewy bodies recognize the mid-size neurofilament subunit
artículo científico publicado en 1997
More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases
artículo científico publicado en 2004
Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy
artículo científico publicado en 2011
Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration
artículo científico publicado en 2005
Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration
artículo científico publicado en 2016
Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome
artículo científico publicado en 2016
Multimodal in vivo and postmortem assessments of tau in Lewy body disorders
artículo científico publicado en 2020
Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
artículo científico publicado en 2017
Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans
artículo científico publicado en 2007
Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).
artículo científico publicado en 2017
Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease
artículo científico publicado en 2015
Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases
artículo científico publicado en 2017
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.
artículo científico publicado en 1998
Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
artículo científico publicado en 2009
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
artículo científico publicado en 2013
Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia
artículo científico publicado en 2014
Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice
artículo científico publicado en 2020
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
artículo científico publicado en 2012
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach
artículo científico publicado en 2011
Neocortical and hippocampal amyloid-β and tau measures associate with dementia in the oldest-old
artículo científico publicado en 2011
Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease
artículo científico publicado en 2017
Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old
artículo científico publicado en 2013
Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells
artículo científico publicado el 1 de marzo de 1992
Neural and neuroendocrine phenotype of neuroblastomas, ganglioneuroblastomas, ganglioneuromas and mature versus embryonic human adrenal medullary cells
artículo científico publicado en 1991
Neural differentiation of rhesus embryonic stem cells
artículo científico publicado en 1998
Neurobiology of human neurons (NT2N) grafted into mouse spinal cord: implications for improving therapy of spinal cord injury
artículo científico publicado en 2000
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
artículo científico publicado en 2003
Neurodegenerative disease biomarkers: guideposts for disease prevention through early diagnosis and intervention
artículo científico publicado en 2011
Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
scientific article published on 01 July 2018
Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
artículo científico publicado en 2004
Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications
artículo científico publicado en 2006
Neurodegenerative tauopathies
artículo científico publicado en 2001
Neurodegenerative tauopathies: human disease and transgenic mouse models
artículo científico publicado en 1999
Neuroendocrine differentiation in poorly differentiated lung carcinomas: a light microscopic and immunohistologic study
artículo científico publicado en 1990
Neurofibrillary pathology and aluminum in Alzheimer's disease.
artículo científico publicado en 1995
Neurofibrillary tangles in progressive supranuclear palsy contain the same tau epitopes identified in Alzheimer's disease PHFtau.
artículo científico publicado en 1996
Neurofilament breakdown products in degenerating rat and human peripheral nerves
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artículo científico publicado el 1 de septiembre de 1984
Neurofilament mRNA is reduced in Parkinson's disease substantia nigra pars compacta neurons
artículo científico publicado en 1993
Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice
scientific article published on 01 September 2000
Neuroimmune interactions in Alzheimer's disease-New frontier with old challenges?
scientific article published on 24 October 2019
Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration
artículo científico publicado en 2008
Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration
artículo científico publicado en 2017
Neuron-specific age-related decreases in dopamine receptor subtype mRNAs
artículo científico publicado en 2003
Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo
artículo científico publicado en 2020
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
artículo científico publicado en 2002
Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition
artículo científico publicado en 2014
Neuronal origin of human esthesioneuroblastoma demonstrated with anti-neurofilament monoclonal antibodies
scientific article published on 01 July 1982
Neurons derived from a human teratocarcinoma cell line establish molecular and structural polarity following transplantation into the rodent brain
artículo científico publicado en 1993
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
artículo científico publicado en 2007
Neuropathologic substrates of Parkinson disease dementia
artículo científico publicado en 2012
Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias
artículo científico publicado en 2005
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
artículo científico publicado en 2017
Neuropathological verisimilitude in animal models of Alzheimer's disease: key to elucidating neurodegenerative pathways and identifying new targets for drug discovery
artículo científico publicado en 2002
Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12
artículo científico publicado en 2015
Neuropathology of synuclein aggregates
artículo científico publicado en 2000
Neuropsychologic assessment in collaborative Parkinson's disease research: a proposal from the National Institute of Neurological Disorders and Stroke Morris K. Udall Centers of Excellence for Parkinson's Disease Research at the University of Pennsy
artículo científico publicado en 2012
Neuropsychological Subgroups in Non-Demented Parkinson's Disease: A Latent Class Analysis
artículo científico publicado en 2017
Neurotrophin receptor TrkC predicts good clinical outcome in medulloblastoma and other primitive neuroectodermal brain tumors.
artículo científico publicado en 2000
Neurotrophin signal transduction in medulloblastoma
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artículo científico publicado el 1 de septiembre de 1997
Neurotrophins and neuronal versus glial differentiation in medulloblastomas and other pediatric brain tumors
artículo científico publicado en 1998
New directions for frontotemporal dementia drug discovery
artículo científico publicado en 2007
New insights into genetic and molecular mechanisms of brain degeneration in tauopathies
artículo científico publicado en 2000
Nitration of tau protein is linked to neurodegeneration in tauopathies
artículo científico publicado en 2003
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update
artículo científico publicado en 2009
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations
artículo científico publicado en 2008
Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study
artículo científico publicado en 2018
Non-Naturally Occurring Small Molecule Microtubule-Stabilizing Agents: A Potential Tactic for CNS-Directed Therapies
artículo científico publicado en 2016
Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease
scholarly article by Umesh Gangishetti et al published 25 September 2018 in Alzheimers Research & Therapy
Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease
artículo científico publicado en 2015
Nonlinear Z-score modeling for improved detection of cognitive abnormality
scientific article published on 05 December 2019
Normalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer's disease
artículo científico publicado en 2020
Nosology of Parkinson's disease: looking for the way out of a quagmire
artículo científico publicado en 2005
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis
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artículo científico publicado en 2020
Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment
artículo científico publicado en 2010
Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
artículo científico publicado en 2002
Novel late-onset Alzheimer disease loci variants associate with brain gene expression
artículo científico publicado en 2012
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.
artículo científico publicado en 2003
Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins
artículo científico publicado en 2014
Olfactory dysfunction occurs in transgenic mice overexpressing human tau protein
artículo científico publicado en 2004
Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease
artículo científico publicado en 2010
Overview of Protein Aggregation in Single, Double, and Triple Neurodegenerative Brain Amyloidoses
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artículo científico publicado el 1 de enero de 2003
Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease
artículo científico publicado en 1997
P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating
artículo científico publicado en 2011
PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease
artículo científico publicado en 2015
PART, a distinct tauopathy, different from classical sporadic Alzheimer disease
artículo científico publicado en 2015
PENN neurodegenerative disease research - in the spirit of Benjamin Franklin.
artículo científico publicado en 2007
PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
artículo científico publicado en 2001
Paclitaxel C-10 carbamates: potential candidates for the treatment of neurodegenerative tauopathies
artículo científico publicado en 2007
Paired helical filament tau in Alzheimer's disease. The kinase connection
artículo científico publicado en 1994
Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease
artículo científico publicado en 2002
Parkinson's disease and related alpha-synucleinopathies are brain amyloidoses
artículo científico publicado en 2003
Parkinson's disease and related synucleinopathies are a new class of nervous system amyloidoses
artículo científico publicado en 2002
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
artículo científico publicado en 2013
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation
artículo científico publicado en 2006
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
artículo científico publicado en 2015
Pathobiology of the Lewy body.
artículo científico publicado en 1999
Pathological 43-kDa Transactivation Response DNA-Binding Protein in Older Adults With and Without Severe Mental Illness
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artículo científico publicado el 1 de octubre de 2010
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
artículo científico publicado en 2007
Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam
scientific article published on 23 August 2007
Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
artículo científico publicado en 2017
Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies
artículo científico publicado en 2006
Pathological tau: a loss of normal function or a gain in toxicity?
scientific article published on 01 September 2005
Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology
artículo científico publicado en 2015
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
artículo científico publicado en 2012
Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
scientific article published in Nature Communications
Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion
artículo científico publicado en 2012
Patterns of striatal degeneration in frontotemporal dementia
artículo científico publicado en 2013
People with Parkinson's disease and normal MMSE score have a broad range of cognitive performance
artículo científico publicado en 2014
Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old
artículo científico publicado en 2014
Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model
artículo científico publicado en 2007
Pharmacokinetic, pharmacodynamic and metabolic characterization of a brain retentive microtubule (MT)-stabilizing triazolopyrimidine
artículo científico publicado en 2015
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease
artículo científico publicado en 2012
Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts
artículo científico
Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls
artículo científico publicado en 1987
Phospholipase pathway in Alzheimer's disease brains: decrease in Galphai in dorsolateral prefrontal cortex
artículo científico publicado en 1999
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions
artículo científico publicado en 2002
Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis
artículo científico publicado en 2017
Phosphorylated tau as a candidate biomarker for amyotrophic lateral sclerosis.
artículo científico publicado en 2014
Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus
artículo científico publicado en 2012
Phosphorylated α-synuclein in Parkinson's disease
artículo científico publicado en 2012
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
artículo científico publicado en 2009
Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases
artículo científico publicado en 1995
Physical activity and cognitive health
artículo científico publicado en 2007
Plaque-associated neuronal proteins: a recurrent motif in neuritic amyloid deposits throughout diverse cortical areas of the Alzheimer's disease brain
scientific article published on 01 December 1994
Plasma EGF and cognitive decline in Parkinson's disease and Alzheimer's disease
artículo científico publicado en 2016
Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease
artículo científico publicado en 2017
Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarker
artículo científico publicado en 2013
Plasma apolipoprotein A1 as a biomarker for Parkinson disease
artículo científico publicado en 2013
Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease
artículo científico publicado en 2012
Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease
artículo científico publicado en 2010
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease
artículo científico publicado en 2012
Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging
artículo científico publicado en 2016
Plasma tau in Alzheimer disease
scientific article published on 30 September 2016
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis
artículo científico
PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats
artículo científico publicado en 2011
Polymorphisms of dopamine receptor and transporter genes and Parkinson's disease
artículo científico publicado en 1995
Postmortem analysis of adrenal-medulla-to-caudate autograft in a patient with Parkinson's disease
artículo científico publicado en 1989
Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists
artículo científico publicado en 2014
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
artículo científico publicado en 2018
Practical utility of amyloid and FDG-PET in an academic dementia center
artículo científico publicado en 2013
Predicting clinical decline and conversion to Alzheimer's disease or dementia using novel Elecsys Aβ(1-42), pTau and tTau CSF immunoassays
scientific article published on 13 December 2019
Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification
artículo científico publicado en 2010
Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance
artículo científico publicado en 2010
Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques
artículo científico publicado en 1999
Prefrontal granular cortex of the rhesus monkey. I. Intrahemispheric cortical afferents
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artículo científico publicado el 26 de agosto de 1977
Prefrontal granular cortex of the rhesus monkey. II. Interhemispheric cortical afferents
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artículo científico publicado el 26 de agosto de 1977
Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD
scientific article published on 01 March 2020
Primary age-related tauopathy (PART): a common pathology associated with human aging
artículo científico publicado en 2014
Primary or secondary prevention for AD: who cares?
artículo científico publicado en 2012
Primitive neuroectodermal tumors of the central nervous system
artículo científico publicado en 1997
Primitive neuroectodermal tumors of the central nervous system in childhood: tumor biological aspects
artículo científico publicado en 1994
Primitive neuroectodermal tumors of the central nervous system. Patterns of expression of neuroendocrine markers, and all classes of intermediate filament proteins.
artículo científico publicado en 1990
Primum non nocere: a call for balance when reporting on CTE
artículo científico publicado en 2019
Production and characterization of two ependymoma xenografts
artículo científico publicado en 1996
Progress from Alzheimer's tangles to pathological tau points towards more effective therapies now.
artículo científico publicado en 2006
Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice
artículo científico publicado en 2016
Progressive Atrophy and Neuron Death for One Year Following Brain Trauma in the Rat
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artículo científico publicado el 1 de octubre de 1997
Proliferation, cell death, and neuronal differentiation in transplanted human embryonal carcinoma (NTera2) cells depend on the graft site in nude and severe combined immunodeficient mice
artículo científico publicado el 1 de agosto de 1995
Properties of antigenic determinants that distinguish neurofibrillary tangles in progressive supranuclear palsy and Alzheimer's disease
artículo científico publicado en 1988
Prospective clinicopathologic studies of schizophrenia: accrual and assessment of patients
artículo científico publicado en 1995
Proteasome Inhibition Stabilizes Tau Inclusions in Oligodendroglial Cells that Occur after Treatment with Okadaic Acid
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artículo científico publicado el 1 de octubre de 2003
Protein Accumulation in Traumatic Brain Injury
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artículo científico publicado el 1 de enero de 2003
Protein astrogliopathies in human neurodegenerative diseases and aging
artículo científico publicado en 2017
Protein mis-folding emerges as a "drugable" target for discovery of novel therapies for neuropsychiatric diseases of aging
artículo científico publicado en 2004
Protein transmission in neurodegenerative disease
artículo científico publicado en 2020
Psychometric Properties of the Clinical Dementia Rating Scale Sum of Boxes in Parkinson's Disease
scientific article published on 29 December 2020
Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.
artículo científico publicado en 2018
Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease
artículo científico publicado en 1996
Purification of paired helical filament tau and normal tau from human brain tissue
artículo científico publicado en 1999
Qualification of a surrogate matrix-based absolute quantification method for amyloid-β₄₂ in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry
artículo científico publicado en 2014
Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI.
artículo científico publicado en 2011
Quality of life and caregiver burden in familial frontotemporal lobar degeneration: Analyses of symptomatic and asymptomatic individuals within the LEFFTDS cohort
artículo científico publicado en 2020
Quantification of modified amyloid beta peptides in Alzheimer disease and Down syndrome brains
artículo científico publicado en 1998
Quantitative assessment of finger tapping characteristics in mild cognitive impairment, Alzheimer's disease, and Parkinson's disease
scientific article published on 04 April 2018
Quantitative neurohistological features of frontotemporal degeneration
artículo científico publicado en 2000
Radioiodinated styrylbenzene derivatives as potential SPECT imaging agents for amyloid plaque detection in Alzheimer's disease
artículo científico publicado en 2002
Rapid and intermittent cotransport of slow component-b proteins
artículo científico publicado en 2007
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
artículo científico publicado en 2017
Rarity of the Alzheimer disease-protective APP A673T variant in the United States
artículo científico publicado en 2015
Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent
artículo científico publicado en 1996
Recent advances in defining the neuropathology of schizophrenia
artículo científico publicado en 1996
Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials.
artículo científico publicado en 2017
Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking
artículo científico publicado en 2012
Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP.
artículo científico publicado en 2013
Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes.
artículo científico publicado en 2003
Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice
scientific article published on 17 November 2018
Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementia
artículo científico publicado en 2017
Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent tau and accumulation of abnormal tau-isoforms (A68 proteins)
artículo científico publicado el 1 de febrero de 1992
Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study
artículo científico publicado en 2010
Relationship between CSF biomarkers of Alzheimer's disease and rates of regional cortical thinning in ADNI data
artículo científico publicado en 2011
Relationship between plaques, tangles, and dystrophic processes in Alzheimer's disease
artículo científico publicado en 1995
Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI
artículo científico publicado en 2013
Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis.
artículo científico publicado en 2002
Reply: LATE to the PART-y
artículo científico publicado en 2019
Research on the Brain
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artículo científico publicado el 22 de octubre de 2003
Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy.
artículo científico publicado en 2004
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.
artículo científico publicado en 2005
Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis
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artículo científico publicado el 23 de noviembre de 2010
Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns
artículo científico publicado en 2020
Role of alpha-synuclein carboxy-terminus on fibril formation in vitro
artículo científico publicado en 2003
Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database
artículo científico publicado en 2015
Role of cerebrospinal fluid biomarkers in clinical trials for Alzheimer's disease modifying therapies
artículo científico publicado en 2014
Rotenone neurotoxicity: a new window on environmental causes of Parkinson's disease and related brain amyloidoses
artículo científico publicado en 2003
Rous-Whipple Award Lecture. The Alzheimer's brain: finding out what's broken tells us how to fix it.
artículo científico publicado en 2005
Saccade abnormalities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer disease
artículo científico publicado en 2012
Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy.
artículo científico publicado en 2016
Selective expression of epitopes in multiphosphorylation repeats of the high and middle molecular weight neurofilament proteins in Alzheimer neurofibrillary tangles
artículo científico publicado en 1989
Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model
artículo científico publicado en 2001
Selective neurodegeneration in murine mucopolysaccharidosis VII is progressive and reversible
artículo científico publicado en 2002
Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study.
artículo científico publicado en 2003
Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease
artículo científico publicado en 2012
Semi-Automated Digital Image Analysis of Pick's Disease and TDP-43 Proteinopathy
artículo científico publicado en 2015
Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration
artículo científico publicado en 2015
Sensitive fluorescence polarization technique for rapid screening of alpha-synuclein oligomerization/fibrillization inhibitors.
artículo científico publicado en 2007
Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD).
artículo científico publicado en 2014
Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain.
artículo científico publicado en 2018
Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques.
artículo científico publicado en 1997
Serial MRI and CSF biomarkers in normal aging, MCI, and AD
artículo científico publicado en 2010
Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers
scientific article published on 01 May 2020
Severe subcortical TDP-43 pathology in sporadic frontotemporal lobar degeneration with motor neuron disease
artículo científico publicado en 2007
Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome
artículo científico publicado en 2020
Sex differences in the genetic predictors of Alzheimer's pathology
scientific article published on 01 September 2019
Sex-specific genetic predictors of Alzheimer's disease biomarkers
artículo científico publicado en 2018
Shapes of the trajectories of 5 major biomarkers of Alzheimer disease
artículo científico publicado en 2012
Signature tau neuropathology in gray and white matter of corticobasal degeneration
artículo científico publicado en 2002
Simulated brain biopsy for diagnosing neurodegeneration using autopsy-confirmed cases.
artículo científico publicado en 2011
Simultaneous HPLC-MS-MS quantification of 8-iso-PGF(2alpha) and 8,12-iso-iPF(2alpha) in CSF and brain tissue samples with on-line cleanup
artículo científico publicado en 2010
Simultaneous analysis of cerebrospinal fluid biomarkers using microsphere-based xMAP multiplex technology for early detection of Alzheimer's disease
artículo científico
Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders.
artículo científico publicado en 2004
Sites of synthesis of chromogranins A and B in the human brain
artículo científico publicado el 1 de abril de 1992
Slow Progressive Accumulation of Oligodendroglial Alpha-Synuclein (α-Syn) Pathology in Synthetic α-Syn Fibril-Induced Mouse Models of Synucleinopathy
artículo científico publicado en 2019
Smaller neuron size in schizophrenia in hippocampal subfields that mediate cortical-hippocampal interactions
artículo científico publicado en 1995
Spatial relationship of AMY protein deposits and different species of Abeta peptides in amyloid plaques of the Alzheimer disease brain.
artículo científico publicado en 1999
Spinal cord neurofibrillary pathology in Alzheimer disease and Guam Parkinsonism-dementia complex
artículo científico publicado en 2001
Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter
artículo científico publicado en 2002
Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long term
artículo científico publicado en 2017
Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis
artículo científico publicado en 2019
Spreading of pathology in neurodegenerative diseases: a focus on human studies
artículo científico publicado en 2015
Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
scientific article published on 19 June 2013
Statins and Cognition in Parkinson's Disease.
artículo científico publicado en 2017
Stereotaxic Targeting of Alpha-Synuclein Pathology in Mouse Brain Using Preformed Fibrils
Strategies for Improving the Postmortem Neuropathological Diagnosis of Alzheimer’s Disease
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artículo científico publicado el 1 de julio de 1997
Studies of childhood brain tumors using immunohistochemistry and microwave technology: methodological considerations
artículo científico
Subicular Dendritic Arborization in Alzheimer's Disease Correlates with Neurofibrillary Tangle Density
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artículo científico publicado el 1 de octubre de 2003
Subjective Cognitive Complaint in Parkinson's Disease Patients with Normal Cognition: Canary in the Coal Mine?
scientific article published on 10 June 2020
Subthalamic nucleus deep brain stimulation in a patient with levodopa-responsive multiple system atrophy. Case report
artículo científico publicado en 2004
Subtypes based on cerebrospinal fluid and magnetic resonance imaging markers in normal elderly predict cognitive decline
artículo científico publicado en 2010
Survival and integration of transplanted postmitotic human neurons following experimental brain injury in immunocompetent rats
artículo científico publicado en 1999
Survival profiles of patients with frontotemporal dementia and motor neuron disease
artículo científico publicado en 2009
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
scientific journal article
Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline
artículo científico publicado en 2010
Synphilin in normal human brains and in synucleinopathies: studies with new antibodies
artículo científico publicado en 2002
Synthesis and characterization of high affinity fluorogenic α-synuclein probes
artículo científico publicado en 2020
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
artículo científico publicado en 2013
Synucleinopathies: clinical and pathological implications
artículo científico publicado en 2001
Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary
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T(1ρ) MRI in Alzheimer's disease: detection of pathological changes in medial temporal lobe
artículo científico publicado en 2011
T1rho (T1ρ) MR imaging in Alzheimer's disease and Parkinson's disease with and without dementia
artículo científico publicado en 2010
T1rho MRI and CSF biomarkers in diagnosis of Alzheimer's disease
artículo científico publicado en 2015
T1rho MRI of Alzheimer's disease
artículo científico publicado en 2008
TAR DNA-binding protein 43 in neurodegenerative disease
artículo científico publicado en 2010
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
artículo científico publicado en 2008
TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss
artículo científico publicado en 2017
TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.
artículo científico publicado en 2017
TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies
artículo científico publicado en 2015
TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies
artículo científico publicado en 2011
TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system.
artículo científico publicado en 2007
TDP-43 in cerebrospinal fluid of patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis
artículo científico publicado en 2008
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
artículo científico publicado en 2007
TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.
artículo científico publicado en 2010
TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions
scientific article published on 01 October 2007
TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
artículo científico publicado en 2014
TDP-43 pathology in a case of hereditary spastic paraplegia with a NIPA1/SPG6 mutation
artículo científico publicado en 2012
TDP-43 pathology, cognitive decline, and dementia in old age
artículo científico publicado en 2013
TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis
artículo científico publicado en 2007
TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: protein misfolding diseases without amyloidosis
artículo científico publicado en 2007
TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease
artículo científico publicado en 2007
TDP-43 skeins show properties of amyloid in a subset of ALS cases
artículo científico publicado en 2012
TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia
artículo científico publicado en 2016
TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions
artículo científico publicado en 2007
TDP-43: a novel neurodegenerative proteinopathy
artículo científico publicado en 2007
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.
artículo científico publicado en 2018
TMEM106B Effect on cognition in Parkinson disease and frontotemporal dementia
scholarly article by Thomas F. Tropea et al published 14 May 2019 in Annals of Neurology
TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions
artículo científico publicado en 2014
TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways
artículo científico publicado en 2012
TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease
artículo científico publicado en 2023
Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease
artículo científico publicado en 2017
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.
artículo científico publicado en 2005
Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression
artículo científico publicado en 2020
Tau and 14-3-3 in glial cytoplasmic inclusions of multiple system atrophy
artículo científico publicado en 2003
Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam
artículo científico publicado en 2002
Tau and axonopathy in neurodegenerative disorders
artículo científico publicado en 2002
Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease
artículo científico publicado en 2020
Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease
artículo científico publicado en 2001
Tau pathology associates with in vivo cortical thinning in Lewy body disorders
scientific article published on 27 October 2020
Tau pathology in a family with dementia and a P301L mutation in tau.
artículo científico publicado en 1999
Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections
artículo científico publicado en 2015
Tau proteins are abnormally expressed in olfactory epithelium of Alzheimer patients and developmentally regulated in human fetal spinal cord
artículo científico publicado en 1993
Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors
artículo científico publicado en 2009
Tau-focused therapy and tau transmission: Implications for Alzheimer’s Disease and related tauopathies
article
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
artículo científico publicado en 2007
Tauists, Baptists, Syners, Apostates, and new data
artículo científico publicado en 2002
Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases
artículo científico publicado en 2016
Temporal progression of hippocampal atrophy and apolipoprotein E gene in Alzheimer's disease
artículo científico publicado en 1996
Terminally differentiated human neurons survive and integrate following transplantation into the traumatically injured rat brain
artículo científico publicado en 1999
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers
artículo científico publicado en 2011
The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans
artículo científico publicado en 2015
The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement
artículo científico publicado en 2016
The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception
artículo científico publicado en 2013
The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.
artículo científico publicado en 2011
The Alzheimer's disease neuroimaging initiative
artículo científico publicado en 2005
The Alzheimer's disease neuroimaging initiative: progress report and future plans
artículo científico publicado en 2010
The Impact of Exercise, Cognitive Activities, and Socialization on Cognitive Function: Results From the National Long-Term Care Survey
artículo científico publicado en 2014
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
artículo científico publicado en 2006
The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort
scientific article published on 31 October 2018
The Penn Parkinson's Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson's disease
artículo científico publicado en 2016
The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates
artículo científico publicado en 2020
The TMEM106B locus and TDP-43 pathology in older persons without FTLD
artículo científico publicado en 2015
The acetylation of tau inhibits its function and promotes pathological tau aggregation
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artículo científico publicado el 1 de enero de 2011
The apolipoprotein E gene in Binswanger's disease and vascular dementia.
artículo científico publicado en 1996
The appearance of dendrites of callosal and corticothalamic neurons in somatosensory cortex of immature rats demonstrated by horseradish peroxidase
artículo científico publicado el 1 de enero de 1975
The art and science of anti-aging therapies
artículo científico publicado en 2005
The cells of origin of the corpus callosum in rat, cat and rhesus monkey
artículo científico publicado en 1974
The cellular and molecular biology of medulloblastoma.
artículo científico publicado en 1995
The cellular and molecular correlates of cognitive impairments in the Alzheimer's disease brain
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artículo científico publicado el 1 de noviembre de 1996
The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies
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artículo científico publicado el 14 de diciembre de 2010
The cytoskeleton in neurodegenerative diseases
artículo científico publicado en 2004
The developmental expression of neurofilament and glial filament proteins in the human pituitary gland: an immunohistochemical study with monoclonal antibodies.
artículo científico publicado en 1984
The disordered neuronal cytoskeleton in Alzheimer's disease
artículo científico publicado en 1992
The expression of alpha-, beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases
artículo científico publicado en 1999
The future of blood-based biomarkers for Alzheimer's disease
artículo científico publicado en 2013
The growth and impact of Alzheimer disease centers as measured by social network analysis
artículo científico publicado en 2014
The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging
artículo científico publicado en 1999
The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology
scientific article published on 06 January 2020
The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice
artículo científico publicado en 2012
The older rabbit as an animal model: implications for Alzheimer's disease
artículo científico publicado en 1996
The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.
artículo científico publicado en 1994
The power of neuroimaging biomarkers for screening frontotemporal dementia
artículo científico publicado en 2014
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
artículo científico publicado en 2002
The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI).
artículo científico publicado en 2013
The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury
artículo científico publicado en 1999
The role of tau in Alzheimer's disease
artículo científico publicado en 2002
The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration
artículo científico publicado en 2010
The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease
artículo científico publicado en 2018
The transcriptional activation domain of VP16 is required for efficient infection and establishment of latency by HSV-1 in the murine peripheral and central nervous systems
artículo científico publicado en 1999
The transitional association between β-amyloid pathology and regional brain atrophy
artículo científico publicado en 2014
The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease
artículo científico publicado en 2013
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
artículo científico publicado en 2013
Therapeutic strategies for tau mediated neurodegeneration
scientific article published on 20 October 2012
Therapeutic strategies for the treatment of tauopathies: Hopes and challenges
artículo científico publicado en 2016
Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant.
artículo científico publicado en 1995
Thorn-shaped astrocytes in the depth of cortical sulci in Western Pacific ALS/Parkinsonism-Dementia complex
scientific article published on 13 July 2020
Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U.
artículo científico publicado en 2013
Total and phosphorylated tau protein as biological markers of Alzheimer's disease
artículo científico publicado en 2009
Toxicity and neuronal infection of a HSV-1 ICP34.5 mutant in nude mice
artículo científico publicado en 1998
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
artículo científico publicado en 2013
Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers
artículo científico publicado en 2019
Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome
artículo científico publicado en 2009
Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin
artículo científico publicado en 2015
Transfectable and transplantable postmitotic human neurons: a potential "platform" for gene therapy of nervous system diseases
artículo científico publicado en 1997
Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh Compound B units of brain Aβ amyloid
artículo científico publicado en 2011
Transgenic animal models of tauopathies
artículo científico publicado en 2005
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
artículo científico publicado en 1996
Transgenic models of tauopathies and synucleinopathies
artículo científico publicado en 1999
Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration.
artículo científico publicado en 2005
Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration
artículo científico publicado en 2002
Transgenic mouse models of tauopathies: prospects for animal models of Pick's disease
artículo científico publicado en 2001
Transmission of tauopathy strains is independent of their isoform composition
scientific article published on 07 January 2020
Transmission of α-synuclein seeds in neurodegenerative disease: recent developments
scientific article published on 13 February 2019
Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats
artículo científico publicado en 1998
Transplantation of embryonic dopamine neurons for severe Parkinson's disease
artículo científico publicado en 2001
Transplanted human neurons derived from a teratocarcinoma cell line (NTera-2) mature, integrate, and survive for over 1 year in the nude mouse brain
artículo científico publicado en 1995
Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging
artículo científico publicado en 1999
Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations
artículo científico publicado en 2008
Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury
artículo científico publicado en 1998
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
scientific article published on 01 April 2020
Typical and atypical pathology in primary progressive aphasia variants
artículo científico
UNC13A polymorphism contributes to frontotemporal disease in sporadic amyotrophic lateral sclerosis
artículo científico publicado en 2018
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
artículo científico publicado en 2006
Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies
artículo científico publicado en 2003
Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies
artículo científico publicado en 2017
Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative
artículo científico publicado en 2018
Unexpected abundance of pathological tau in progressive supranuclear palsy white matter
artículo científico publicado en 2006
Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice
artículo científico publicado en 2016
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects
artículo científico publicado en 2010
Update on the neuropathological diagnosis of frontotemporal dementias
artículo científico publicado en 2001
Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice
artículo científico publicado en 2009
Utility of amyloid PET in the differential diagnosis of dementia: An autopsy-confirmed series
scholarly article by Manja Lehmann et al published July 2013 in Alzheimer's and Dementia
Utility of amyloid PET in the differential diagnosis of dementia: An autopsy-confirmed series
scholarly article by Manja Lehmann et al published July 2013 in Alzheimer's and Dementia
Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium
scientific article published on 01 January 2020
VENTRICULAR MAPS IN 804 SUBJECTS CORRELATE WITH COGNITIVE DECLINE, CSF PATHOLOGY, AND IMMINENT ALZHEIMER'S DISEASE
artículo científico publicado en 2010
Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects
artículo científico publicado en 2015
Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects
artículo científico publicado en 2015
Variables associated with hippocampal atrophy rate in normal aging and mild cognitive impairment
artículo científico publicado en 2014
Variants associated with Gaucher disease in multiple system atrophy
artículo científico publicado en 2015
Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration
artículo científico publicado en 2008
Vascular disease and dementias: paradigm shifts to drive research in new directions
artículo científico publicado en 2012
Ventricular maps in 804 ADNI subjects: correlations with CSF biomarkers and clinical decline
artículo científico publicado en 2010
Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury.
artículo científico publicado en 2004
Vulnerability of the neuronal cytoskeleton in aging and Alzheimer disease: widespread involvement of all three major filament systems.
artículo científico publicado en 1990
Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI).
artículo científico publicado en 2005
White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration
artículo científico publicado en 2013
Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson's disease
scientific article published on 08 August 2016
alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases
artículo científico publicado en 2004
alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease
artículo científico publicado en 2004
alpha-synuclein is developmentally expressed in cultured rat brain oligodendrocytes.
artículo científico publicado en 2000
p38 mitogen-activated protein kinase-independent induction of gadd45 expression in nerve growth factor-induced apoptosis in medulloblastomas
scientific article published on 05 September 2001
Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration
artículo científico publicado en 2014
α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies
artículo científico publicado en 2011
α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons
artículo científico publicado en 2019
α-Synuclein modulates tau spreading in mouse brains
artículo científico publicado en 2021
α-Synuclein pathology in Parkinson's disease and related α-synucleinopathies
scientific article published on 03 June 2019