Lista de obras - Gemma Fabrias - Dominio Público Uruguay

19F NMR analyses of some cyclopropane derivatives

3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate.

artículo científico publicado en 2012

3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.

artículo científico publicado en 2016

A Convenient and Stereoselective Synthesis of (3Z,5Z)-5-Fluorotetrade Cadien-1-yl Acetate, A Fluorinated Analog of the sex Pheromone of the CarpenterwormPrionoxistus robiniae(Peck)

A Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor

artículo científico publicado en 2020

A new member of the PBAN family in Spodoptera littoralis: molecular cloning and immunovisualisation in scotophase hemolymph

artículo científico publicado en 2002

A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease.

artículo científico publicado en 2010

Acid ceramidase as a therapeutic target in metastatic prostate cancer.

artículo científico publicado en 2013

Action of PBAN and related peptides on pheromone biosynthesis in isolated pheromone glands of the redbanded leafroller moth, Argyrotaenia velutinana

artículo científico publicado en 1994

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols.

artículo científico publicado en 2015

Activity-Based Imaging of Acid Ceramidase in Living Cells

scientific article published on 02 May 2019

Analogs of sex pheromone of processionary moth,Thaumetopoea pityocampa: Synthesis and biological activity

artículo científico publicado en 1988

Anomalous formation of 1,1,4-tribromohex-1-en-3-one in the wittig reaction of 2-halopent-2-enals with dibromomethylene triphenylphosphorane

Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis.

artículo científico publicado en 2013

Azide-tagged sphingolipids: new tools for metabolic flux analysis

artículo científico publicado en 2015

C6-Ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth ⬇️

artículo científico publicado el 21 de septiembre de 2011

Cellular changes that accompany shedding of human corneocytes.

artículo científico publicado en 2012

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer

artículo científico publicado en 2012

Click and count: specific detection of acid ceramidase activity in live cells

artículo científico publicado en 2020

Comparative sex pherome biosynthesis in Thaumetopoea pityocampa and T. processionea: a rationale for the phenotypic variation in the sex pherome within the genus Thaumetopoea

artículo científico publicado en 2003

Control of the biosynthetic pathway of Sesamia nonagrioides sex pheromone by the pheromone biosynthesis activating neuropeptide

artículo científico publicado en 2000

Coordinated regulation of the orosomucoid-like gene family expression controls de novo ceramide synthesis in mammalian cells.

artículo científico publicado en 2014

De novo ceramide synthesis is involved in acute inflammation during labor

artículo científico publicado en 2016

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization

artículo científico publicado en 2016

Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms.

artículo científico publicado en 2016

Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains

article

Effect of prenatal steroidal inhibition of sPLA2 in a rat model of preterm lung.

artículo científico publicado en 2015

Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis

scientific journal article

Fluorinated analogs of insect sex pheromones

article by F. Camps et al published September 1984 in Cellular and Molecular Life Sciences

From the configurational preference of dihydroceramide desaturase-1 towards Δ6-unsaturated substrates to the discovery of a new inhibitor.

artículo científico publicado en 2017

Identification and biosynthesis of (E,E)-10,12-tetradecadienyl acetate in Spodoptera littoralis female sex pheromone gland

artículo científico publicado en 1997

Inhibition of acid ceramidase by a 2‐substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N‐(4‐hydroxyphenyl) retinamide ⬇️

artículo científico publicado el 28 de diciembre de 2010

Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II.

artículo científico publicado en 2014

Introduction to the special issue: Inhibitors of enzymes involved in lipid metabolism

scientific article published on 17 August 2015

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile

artículo científico publicado en 2014

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

artículo científico publicado en 2016

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: new insights into the pathogenesis of Krabbe's disease

artículo científico publicado en 2014

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis

artículo científico publicado en 2015

Natural grape extracts regulate colon cancer cells malignancy.

artículo científico publicado en 2015

Natural products as platforms for the design of sphingolipid-related anticancer agents

artículo científico

New fluorogenic probes for neutral and alkaline ceramidases

scientific article published on 29 March 2019

Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna

artículo científico publicado en 2015

On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging.

artículo científico publicado en 2014

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1

artículo científico publicado en 2012

Sila-pheromones: Silicon analogues of the female sex pheromone of the processionary moth thaumetopoea pityocampa

article by Gemma Arsequell et al published January 1990 in Tetrahedron Letters

Specific sphingolipid content decrease in Cerkl knockdown mouse retinas

scientific journal article

Stereospecificity of the (Z)-9 desaturase that converts (E)-11-tetradecenoic acid into (Z,E)-9,11-tetradecadienoic acid in the biosynthesis of Spodoptera littoralis sex pheromone

artículo científico publicado en 2001

Straightforward access to spisulosine and 4,5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells.

artículo científico publicado en 2013

Synthesis of [14,14,14-2H3] 12-hydroxytetradecanoic acid and [13,14-2H2] 11-hydroxytetradecanoic acid useful as tracers to study a (11E)-desaturation reaction in Spodoptera littoralis

artículo científico publicado en 1996

Synthesis of a fluorinated analog of the sex pheromone of the processionary moth thaumetopoea. pityocampa(denis and schiff.)

article by Francisco Camps et al published January 1986 in Tetrahedron

Synthesis of dienic fluorinated analogs of insect sex pheromones

article by Francisco Camps et al published January 1984 in Tetrahedron

Systemic ceramide accumulation leads to severe and varied pathological consequences.

artículo científico publicado en 2013

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

scientific article published on 13 May 2020

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells.

artículo científico publicado en 2017

Thiafatty acids as tracers to investigate biosynthetic pathways of lepidopteran sex pheromones

artículo científico publicado en 2001

cis- versus trans-ceramides: effects of the double bond on conformation and H-bonding interactions

artículo científico publicado en 2009

Lista de obras de Gemma Fabrias

19F NMR analyses of some cyclopropane derivatives

3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate.

3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.

A Convenient and Stereoselective Synthesis of (3Z,5Z)-5-Fluorotetrade Cadien-1-yl Acetate, A Fluorinated Analog of the sex Pheromone of the CarpenterwormPrionoxistus robiniae(Peck)

A Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor

A new member of the PBAN family in Spodoptera littoralis: molecular cloning and immunovisualisation in scotophase hemolymph

A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease.

Acid ceramidase as a therapeutic target in metastatic prostate cancer.

Action of PBAN and related peptides on pheromone biosynthesis in isolated pheromone glands of the redbanded leafroller moth, Argyrotaenia velutinana

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols.

Activity-Based Imaging of Acid Ceramidase in Living Cells

Analogs of sex pheromone of processionary moth,Thaumetopoea pityocampa: Synthesis and biological activity

Anomalous formation of 1,1,4-tribromohex-1-en-3-one in the wittig reaction of 2-halopent-2-enals with dibromomethylene triphenylphosphorane

Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis.

Azide-tagged sphingolipids: new tools for metabolic flux analysis

C6-Ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth ⬇️

Cellular changes that accompany shedding of human corneocytes.

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer

Click and count: specific detection of acid ceramidase activity in live cells

Comparative sex pherome biosynthesis in Thaumetopoea pityocampa and T. processionea: a rationale for the phenotypic variation in the sex pherome within the genus Thaumetopoea

Control of the biosynthetic pathway of Sesamia nonagrioides sex pheromone by the pheromone biosynthesis activating neuropeptide

Coordinated regulation of the orosomucoid-like gene family expression controls de novo ceramide synthesis in mammalian cells.

De novo ceramide synthesis is involved in acute inflammation during labor

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization

Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms.

Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains

Effect of prenatal steroidal inhibition of sPLA2 in a rat model of preterm lung.

Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis

Fluorinated analogs of insect sex pheromones

From the configurational preference of dihydroceramide desaturase-1 towards Δ6-unsaturated substrates to the discovery of a new inhibitor.

Identification and biosynthesis of (E,E)-10,12-tetradecadienyl acetate in Spodoptera littoralis female sex pheromone gland

Inhibition of acid ceramidase by a 2‐substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N‐(4‐hydroxyphenyl) retinamide ⬇️

Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II.

Introduction to the special issue: Inhibitors of enzymes involved in lipid metabolism

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: new insights into the pathogenesis of Krabbe's disease

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis

Natural grape extracts regulate colon cancer cells malignancy.

Natural products as platforms for the design of sphingolipid-related anticancer agents

New fluorogenic probes for neutral and alkaline ceramidases

Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna

On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging.

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1

Sila-pheromones: Silicon analogues of the female sex pheromone of the processionary moth thaumetopoea pityocampa

Specific sphingolipid content decrease in Cerkl knockdown mouse retinas

Stereospecificity of the (Z)-9 desaturase that converts (E)-11-tetradecenoic acid into (Z,E)-9,11-tetradecadienoic acid in the biosynthesis of Spodoptera littoralis sex pheromone

Straightforward access to spisulosine and 4,5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells.

Synthesis of [14,14,14-2H3] 12-hydroxytetradecanoic acid and [13,14-2H2] 11-hydroxytetradecanoic acid useful as tracers to study a (11E)-desaturation reaction in Spodoptera littoralis

Synthesis of a fluorinated analog of the sex pheromone of the processionary moth thaumetopoea. pityocampa(denis and schiff.)

Synthesis of dienic fluorinated analogs of insect sex pheromones

Systemic ceramide accumulation leads to severe and varied pathological consequences.

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells.

Thiafatty acids as tracers to investigate biosynthetic pathways of lepidopteran sex pheromones

cis- versus trans-ceramides: effects of the double bond on conformation and H-bonding interactions