Filtros de búsqueda

Lista de obras de John D. Lambris

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

A 'rule of 3' to revive Greek science, research and innovation.

artículo científico publicado en 2015

A Phase-Variable Surface Layer from the Gut Symbiont Bacteroides thetaiotaomicron

artículo científico publicado en 2015

A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins

artículo científico publicado en 2013

A complement receptor C5a antagonist regulates epithelial to mesenchymal transition and crystallin expression after lens cataract surgery in mice

artículo científico publicado en 2011

A complement-IL-4 regulatory circuit controls liver regeneration

artículo científico publicado en 2011

A flow-through optical sensor system for label-free detection of proteins and DNA

A functional C5a anaphylatoxin receptor in a teleost species

artículo científico publicado en 2004

A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor, IkappaBalpha

artículo científico publicado en 2005

A method for analysing lymphocyte surface antigens

scientific article published on 01 January 1980

A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family

artículo científico publicado en 2009

A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration

artículo científico publicado en 2014

A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways.

artículo científico publicado en 2006

A novel C5aR-tissue factor crosstalk in neutrophils links innate immunity to coagulation pathways

A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration.

artículo científico publicado en 2001

A protective role for the fifth complement component (c5) in allergic airway disease

artículo científico publicado en 2006

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

artículo científico publicado en 2006

A role for Lys-His-Gly-NH2 in avian and murine B cell development

artículo científico publicado en 1989

A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin

artículo científico publicado en 2006

A structural basis for complement inhibition by Staphylococcus aureus

artículo científico publicado en 2007

A sweet spot to control complement-induced inflammation

scientific article published on 01 September 2012

Absence of mannose-binding lectin prevents hyperglycemic cardiovascular complications

artículo científico publicado en 2011

Accumulation of viruslike particles in a yeast mutant lacking a mitochondrial pore protein

artículo científico publicado en 1989

Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor

artículo científico publicado en 2011

Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation

scientific article published on April 2008

Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis.

scientific article published on February 2014

Advances in understanding the structure, function, and mechanism of the SCIN and Efb families of Staphylococcal immune evasion proteins

artículo científico

Aegean reflections on innate immunity

artículo científico publicado en 2013

Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood

artículo científico publicado en 2021

Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII.

artículo científico

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

artículo científico publicado en 2010

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

artículo científico publicado en 2010

Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression.

artículo científico publicado en 2012

Ancient origin of the complement system: emerging invertebrate models.

artículo científico publicado en 2007

Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity

artículo científico publicado en 2009

Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin

artículo científico publicado en 2004

Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research – 20 years of experience and future perspectives

artículo científico publicado en 2022

Applying complement therapeutics to rare diseases.

artículo científico publicado en 2015

Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person

artículo científico publicado en 2011

Attenuation of Staphylococcus aureus-Induced Bacteremia by Human Mini-Antibodies Targeting the Complement Inhibitory Protein Efb

artículo científico publicado en 2015

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

artículo científico publicado en 2019

Author Correction: Complement as a target in COVID-19?

artículo científico publicado en 2020

Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating

artículo científico publicado en 2012

Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface

article

Blood protein-polymer adsorption: implications for understanding complement-mediated hemoincompatibility

artículo científico publicado en 2011

C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood

artículo científico publicado en 2013

C3 glomerulopathy - understanding a rare complement-driven renal disease

artículo científico publicado en 2019

C3 promotes expansion of CD8+ and CD4+ T cells in a Listeria monocytogenes infection

artículo científico publicado en 2009

C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury

artículo científico publicado en 2004

C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion

artículo científico publicado en 2007

C3a receptor antagonist attenuates brain injury after intracerebral hemorrhage

artículo científico publicado en 2008

C5L2 receptor disruption enhances the development of diet-induced insulin resistance in mice

artículo científico publicado en 2012

C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome

artículo científico publicado en 2008

C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury☆,☆☆

artículo científico publicado en 2003

C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist

artículo científico publicado en 2005

C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay

artículo científico publicado en 2012

C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing

artículo científico publicado en 2011

CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis

artículo científico publicado en 2020

CD59 efficiently protects human NT2-N neurons against complement-mediated damage

artículo científico publicado en 2007

CMAP: Complement Map Database

artículo científico publicado en 2013

Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

artículo científico publicado en 2010

Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD

artículo científico publicado en 2008

Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus

artículo científico publicado en 2007

Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor

scientific article published on 03 July 2019

Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

scientific article published on 19 February 2014

CiC3-1a-mediated chemotaxis in the deuterostome invertebrate Ciona intestinalis (Urochordata).

artículo científico publicado en 2003

Clinical promise of next-generation complement therapeutics

scientific article published on 19 July 2019

Cloning and structure of three rainbow trout C3 molecules: a plausible explanation for their functional diversity

artículo científico publicado en 2001

Cloning of three trout C3 isoforms: structural, functional, and phylogenetic analysis

Coarse-Grained Conformational Sampling of Protein Structure Improves the Fit to Experimental Hydrogen-Exchange Data.

artículo científico publicado en 2017

Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex.

artículo científico publicado en 2016

Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.

artículo científico publicado en 2015

Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.

artículo científico publicado en 2017

Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist.

artículo científico publicado en 2004

Complement C3 inhibition by compstatin Cp40 prevents intra- and extravascular hemolysis of red blood cells

scientific article published on 31 January 2020

Complement C3 inhibitor Cp40 attenuates xenoreactions in pig hearts perfused with human blood.

artículo científico publicado en 2016

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

scientific article published on 19 September 2020

Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery.

artículo científico publicado en 2017

Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β.

artículo científico publicado en 2011

Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.

artículo científico publicado en 2015

Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects

artículo científico publicado en 2017

Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis

artículo científico publicado en 2022

Complement C5a receptor is essential for the optimal generation of antiviral CD8+ T cell responses

artículo científico publicado en 2004

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

artículo científico publicado en 2003

Complement C5a-Induced Changes in Neutrophil Morphology During Inflammation

artículo científico publicado en 2017

Complement C5a-Mediated TAM-ing of Antitumor Immunity Drives Squamous Carcinogenesis

artículo científico publicado en 2018

Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches

artículo científico publicado en 2015

Complement Receptors (CR) and Cytotoxic Responses: Monoclonal Antibodies Directed Against CR1 AMD CR3 Inhibit the Generation of Human Allospecific and Virus Specific Cytotoxic Cells in Vitro

article

Complement activation by CpG in a human whole blood loop system: mechanisms and immunomodulatory effects

artículo científico publicado en 2009

Complement activation is critical to airway hyperresponsiveness after acute ozone exposure

artículo científico publicado en 2003

Complement activation on neutrophils initiates endothelial adhesion and extravasation

artículo científico publicado en 2019

Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression

artículo científico publicado en 2021

Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration

artículo científico publicado en 2013

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

artículo científico publicado en 2010

Complement and Neutrophil Function Changes After Liver Resection in Humans

artículo científico publicado en 2009

Complement and coagulation: strangers or partners in crime?

artículo científico publicado en 2007

Complement and dysbiosis in periodontal disease ⬇️

artículo científico publicado el 1 de noviembre de 2012

Complement and innate immunity.

artículo científico publicado en 2000

Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

scientific article published on 06 August 2020

Complement as a target in COVID-19?

scientific article published on 23 April 2020

Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection

artículo científico publicado en 2003

Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense ⬇️

artículo científico publicado en 2016

Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1

artículo científico publicado en 2010

Complement component C3aR constitutes a novel regulator for chick eye morphogenesis.

artículo científico publicado en 2017

Complement component C5a mediates hemorrhage-induced intestinal damage

artículo científico publicado en 2008

Complement component c5a is integral to the febrile response of mice to lipopolysaccharide

artículo científico publicado en 2005

Complement deficiency promotes cutaneous wound healing in mice

artículo científico publicado en 2014

Complement deposits on ocular tissues adjacent to sites of inflammation

artículo científico publicado en 2007

Complement diversity: a mechanism for generating immune diversity?

artículo científico publicado en 1998

Complement evasion by human pathogens

artículo científico publicado en 2008

Complement fragment C3a controls mutual cell attraction during collective cell migration

artículo científico publicado en 2011

Complement in Action: An Analysis of Patent Trends from 1976 Through 2011 ⬇️

artículo científico publicado el 1 de enero de 2013

Complement in cancer: untangling an intricate relationship.

artículo científico publicado en 2017

Complement in disease: a defence system turning offensive

artículo científico publicado en 2016

Complement in immune and inflammatory disorders: pathophysiological mechanisms

artículo científico publicado en 2013

Complement in immune and inflammatory disorders: therapeutic interventions

artículo científico publicado en 2013

Complement in inflammatory tissue damage and disease

article

Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape

artículo científico publicado en 2014

Complement in urochordates: cloning and characterization of two C3-like genes in the ascidian Ciona intestinalis

artículo científico publicado en 2002

Complement inhibition decreases early fibrogenic events in the lung of septic baboons

artículo científico publicado en 2015

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

artículo científico publicado en 2010

Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies.

artículo científico publicado en 2016

Complement inhibition in a xenogeneic model of interactions between human whole blood and porcine endothelium

artículo científico publicado en 2014

Complement inhibition in cancer therapy

artículo científico

Complement inhibition in pre-clinical models of periodontitis and prospects for clinical application

artículo científico publicado en 2016

Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques

artículo científico publicado en 2015

Complement modulates the cutaneous microbiome and inflammatory milieu

artículo científico publicado en 2013

Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

artículo científico publicado en 2020

Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair

artículo científico publicado en 2017

Complement therapeutics

artículo científico publicado en 2016

Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention

artículo científico publicado en 2015

Complement-Dependent Mechanisms and Interventions in Periodontal Disease

artículo científico publicado en 2019

Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4.

artículo científico publicado en 2017

Complement-dependent neutrophil recruitment is critical for the development of elastase-induced abdominal aortic aneurysm

artículo científico publicado en 2009

Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF

artículo científico publicado en 2002

Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis

artículo científico publicado en 2010

Complement-targeted therapeutics

artículo científico publicado en 2007

Complement-targeted therapeutics in periodontitis

artículo científico publicado en 2013

Complement-triggered pathways orchestrate regenerative responses throughout phylogenesis

artículo científico publicado en 2013

Complement: More than killing

scholarly article by John D. Lambris published February 2013 in Seminars in Immunology

Complement: an inflammatory pathway fulfilling multiple roles at the interface of innate immunity and development.

artículo científico publicado en 2005

Complement: more than a 'guard' against invading pathogens?

artículo científico publicado en 2002

Complement: structure, functions, evolution, and viral molecular mimicry

artículo científico publicado en 2003

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

artículo científico publicado en 2010

Complementing the Cancer-Immunity Cycle

Complexity of complement activation in sepsis

artículo científico publicado en 2008

Compstatin Cp40 blocks hematin-mediated deposition of C3b fragments on erythrocytes: Implications for treatment of malarial anemia

artículo científico publicado en 2016

Compstatin analog Cp40 inhibits complement dysregulation in vitro in C3 glomerulopathy

artículo científico publicado en 2015

Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3.

artículo científico publicado en 2006

Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts

article

Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3.

artículo científico publicado en 2003

Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention

artículo científico publicado en 2015

Compstatin: a complement inhibitor on its way to clinical application

artículo científico publicado en 2008

Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water

artículo científico publicado en 2007

Conformational differences between surface-bound and fluid-phase complement-component-C3 fragments. Epitope mapping by cDNA expression ⬇️

artículo científico publicado el 15 de marzo de 1992

Conformational interconversion in compstatin probed with molecular dynamics simulations

artículo científico publicado en 2003

Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin

artículo científico publicado en 2014

Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18.

artículo científico publicado en 2015

Contribution of chondroitin sulfate A to the binding of complement proteins to activated platelets

artículo científico publicado en 2010

Contribution of the Innate Immune System to Autoimmune Diabetes: A Role for the CR1/CR2 Complement Receptors

Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin

artículo científico publicado en 2016

Corrigendum: Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

scientific article published on 03 May 2019

Coupling of C3b to erythrocytes by disulfide bond formation: Preparation of EC3b for hemolytic and complement receptor assays

artículo científico publicado en 1983

Cross-disciplinary research stirs new challenges into the study of the structure, function and systems biology of complement.

artículo científico publicado en 2006

Crosstalk between the coagulation and complement systems in sepsis

artículo científico publicado en 2014

Crosstalk pathways between Toll-like receptors and the complement system

artículo científico publicado en 2010

Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN).

artículo científico publicado en 2009

Current understanding of periodontal disease pathogenesis and targets for host-modulation therapy

artículo científico publicado en 2020

Cutting edge: members of the Staphylococcus aureus extracellular fibrinogen-binding protein family inhibit the interaction of C3d with complement receptor 2.

artículo científico publicado en 2008

Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model

artículo científico publicado en 2008

DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity

artículo científico publicado en 2006

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids

artículo científico publicado en 2005

Development of a new pharmacophore model that discriminates active compstatin analogs

artículo científico publicado en 2008

Diet-induced hepatocellular carcinoma in genetically predisposed mice

artículo científico publicado en 2009

Differential capacity for complement receptor-mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte

artículo científico publicado en 2016

Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production

artículo científico publicado en 2005

Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood

artículo científico publicado en 2012

Differentiation-dependent changes in human trophoblast expression of decay-accelerating factor are modulated by 3?,5? cyclic adenosine monophosphate

scientific article published on 01 January 1997

Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation

artículo científico publicado en 2008

Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family

artículo científico publicado en 2012

Diversity in the C3b contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family

artículo científico publicado en 2012

Diversity of the third form of complement, C3, in fish: functional characterization of five forms of C3 in the diploid fish Sparus aurata

artículo científico publicado en 1997

Do cryopreserved mesenchymal stromal cells display impaired immunomodulatory and therapeutic properties?

artículo científico publicado en 2014

Does complement play a role in bone development and regeneration?

artículo científico

Drusen complement components C3a and C5a promote choroidal neovascularization

artículo científico publicado en 2006

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry

artículo científico publicado en 2008

Early post-operative measurement of cytokine plasma levels combined with pre-operative bilirubin levels identify high-risk patients after liver resection

artículo científico publicado en 2010

Editorial: Therapeutic Modulation of the Complement System: Clinical Indications and Emerging Drug Leads

scientific article published on 01 January 2019

Effect of a putative B cell superantigen on complement

artículo científico publicado en 1995

Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation

artículo científico publicado en 2004

Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement

artículo científico publicado en 2006

Electrostatic contributions drive the interaction betweenStaphylococcus aureusprotein Efb-C and its complement target C3d

artículo científico publicado en 2008

Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins

artículo científico publicado en 2005

Epitope Mapping Using the X-Ray Crystallographic Structure of Complement Receptor Type 2 (CR2)/CD21: Identification of a Highly Inhibitory Monoclonal Antibody That Directly Recognizes the CR2-C3d Interface

scientific article published on 01 November 2001

Erythrocytes Reveal Complement Activation in Patients with COVID-19

artículo científico publicado en 2020

Escherichia coli-induced coagulation activation and pentraxin 3 release is highly dependent on complement and CD14

artículo científico publicado en 2012

Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

artículo científico publicado en 2002

Evidence for multiple sites of interaction in C3 for complement receptor type 2 (C3d/EBV receptor, CD21)

scientific article published on 01 November 1991

Evolution and diversity of the complement system of poikilothermic vertebrates

artículo científico publicado en 1998

Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria

scientific article published on 14 February 2018

Exploring the complement interaction network using surface plasmon resonance.

artículo científico publicado en 2007

Expression and function of C5a receptor in mouse microvascular endothelial cells

artículo científico publicado en 2002

Expression of CR2/EBV receptors on human thymocytes detected by monoclonal antibodies

scientific article published on 01 August 1988

Expression of EBV/C3d receptors on T cells: biological significance

artículo científico publicado en 1993

Expression of complement 3 and complement 5 in newt limb and lens regeneration.

artículo científico publicado en 2003

Expression of compstatin in Escherichia coli: incorporation of unnatural amino acids enhances its activity

artículo científico publicado en 2005

Factor H C-Terminal Domains Are Critical for Regulation of Platelet/Granulocyte Aggregate Formation.

artículo científico publicado en 2017

Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule

artículo científico publicado en 2019

Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial Pathogen Streptococcus pyogenes

artículo científico publicado en 2017

Fluorescent labelling of proteins of lymphocyte plasma membranes

artículo científico publicado en 1979

From orphan drugs to adopted therapies: Advancing C3-targeted intervention to the clinical stage.

artículo científico publicado en 2016

Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis

artículo científico publicado en 2018

Functional maturation of murine B lymphocyte precursors—III. Soluble factors involved in the regulation of growth and differentiation

scientific article published on 01 November 1988

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

artículo científico publicado en 2003

G protein coupled receptor specificity for C3a and compound 48/80-induced degranulation in human mast cells: roles of Mas-related genes MrgX1 and MrgX2.

artículo científico publicado en 2011

Generation of C5a in the absence of C3: a new complement activation pathway

article

Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-CS antibodies

artículo científico publicado en 1987

Generation of analogues of the clinical complement inhibitor compstatin with improved potency and pharmacokinetics

artículo científico publicado en 2010

Generation of three different fragments of bound C3 with purified factor I or serum. II. Location of binding sites in the C3 Fragments for Factors B and H, complement receptors , and bovine conglutinin ⬇️

artículo científico publicado el 1 de agosto de 1983

Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis

artículo científico publicado en 2014

Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization

artículo científico publicado en 2012

Gingival Exudatome Dynamics Implicate Inhibition of the Alternative Complement Pathway in the Protective Action of the C3 Inhibitor Cp40 in Nonhuman Primate Periodontitis

scientific article published on 29 August 2018

H1 10:00 Phylogeny and diversity of the third complement component C3

scholarly article

H7 11:45 Structural and functional characterization of B/C2 complement molecules in teleost fish ⬇️

artículo científico publicado en 1997

Herpes simplex virus type 1 evades the effects of antibody and complement in vivo

artículo científico publicado en 2002

High-Fat Diet-Induced Complement Activation Mediates Intestinal Inflammation and Neoplasia, Independent of Obesity

artículo científico publicado en 2016

Hormonal regulation of complement factor B in human endometrium

artículo científico publicado en 1993

Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature

scholarly article

Hydrogen/deuterium exchange mass spectrometry: potential for investigating innate immunity proteins

artículo científico publicado en 2007

Hydrophobic Effect and Hydrogen Bonds Account for the Improved Activity of a Complement Inhibitor, Compstatin

article

Hypoxia and reoxygenation of primary human hepatocytes induce proteome changes of glucose metabolism, oxidative protection and peroxisomal function ⬇️

artículo científico publicado el 1 de octubre de 2010

Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes.

artículo científico publicado en 1982

Illuminating the latest advances in innate immunity on the island of the sun god ⬇️

artículo científico publicado el 1 de noviembre de 2010

Immune competence of the Ciona intestinalis pharynx: Complement system-mediated activity

artículo científico publicado en 2012

Immune evasion of Moraxella catarrhalis involves ubiquitous surface protein A-dependent C3d binding

artículo científico publicado en 2011

Impaired ability of complement activation via the alternative pathway C3 convertase caused by a single-point mutation in the beta chain of C3

artículo científico publicado en 2010

Importance of Factors H and I for the Adherence of C3b-Coated Erythrocytes to Cells

artículo científico publicado en 1983

In vivo significance of ITK-SLP-76 interaction in cytokine production

artículo científico publicado en 2010

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

artículo científico publicado en 2016

Increased C5a receptor expression in sepsis

artículo científico publicado en 2002

Increased C5a receptor expression in sepsis

Inducing and characterizing liver regeneration in mice: Reliable models, essential "readouts" and critical perspectives

artículo científico publicado en 2013

Induction of complement C3a receptor responses by kallikrein-related peptidase 14.

artículo científico publicado en 2013

Inhibition of Heparin/Protamine Complex-Induced Complement Activation by Compstatin in Baboons

artículo científico publicado en 2000

Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantation

artículo científico publicado en 2013

Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3

artículo científico publicado en 2016

Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury.

artículo científico publicado en 2015

Innate immune responses to trauma

artículo científico publicado en 2018

Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategies

artículo científico publicado en 2011

Innate immunity in the Aegean: ancient pathways for today's survival

artículo científico publicado en 2002

Innate immunity mechanisms

artículo científico publicado el 1 de enero de 2012

Integrated Computational and Experimental Approach for Lead Optimization and Design of Compstatin Variants with Improved Activity

article

Interaction between Epstein-Barr virus and a T cell line (HSB-2) via a receptor phenotypically distinct from complement receptor type 2

artículo científico publicado el 1 de mayo de 1992

Interaction between the coagulation and complement system

artículo científico publicado en 2008

Interaction of Streptococcus pyogenes with extracellular matrix components resulting in immunomodulation and bacterial eradication

artículo científico publicado en 2020

Interactions between coagulation and complement--their role in inflammation

artículo científico publicado en 2011

Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb

scientific article published on 14 May 2019

Invited commentary

Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model

artículo científico publicado en 2017

Is complement good or bad for cancer patients? A new perspective on an old dilemma

artículo científico publicado en 2009

Isolation and characterization of the third complement component of axolotl (Ambystoma mexicanum)

artículo científico publicado en 1990

Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) open reading frame 4 protein (kaposica) is a functional homolog of complement control proteins

artículo científico publicado en 2003

Key role of complement receptor 1 in the initial binding of Escherichia coli and Neisseria meningitidis to erythrocytes in human whole blood

artículo científico publicado en 2009

Key role of complement receptor 1 in the initial binding of Escherichia coli and Neisseria meningitidis to erythrocytes in human whole blood

artículo científico publicado en 2008

Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b.

artículo científico publicado en 2002

Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220.

artículo científico publicado en 2001

Liver inflammation and regeneration: two distinct biological phenomena or parallel pathophysiologic processes?

artículo científico publicado en 2006

Liver regeneration: a link to inflammation through complement.

artículo científico publicado en 2006

Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist

artículo científico publicado en 2012

Local endothelial complement activation reverses endothelial quiescence, enabling t-cell homing, and tumor control during t-cell immunotherapy.

artículo científico publicado en 2017

Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38kDa tryptic fragment of factor H ⬇️

artículo científico publicado el 1 de diciembre de 1984

Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement

artículo científico publicado en 2011

Lymphocyte mitogenesis induced by monoclonal antibodies to the T3 complex. Differential modulation by human IgG

artículo científico publicado en 1984

Mass spectrometric analyses of the activation products of the third component of complement

article

Mechanisms of action of differentiation inducers: detection of inducer binding protein(s) in murine erythroleukemia cells.

artículo científico publicado en 2005

Mediation of a non-proteolytic activation of complement component C3 by phospholipid vesicles.

artículo científico publicado en 2014

Membranoproliferative glomerulonephritis type II (dense deposit disease): an update

artículo científico publicado en 2005

Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses

artículo científico publicado en 2011

Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS.

artículo científico publicado en 2016

Microbial hijacking of complement-toll-like receptor crosstalk

artículo científico publicado en 2010

Microbial manipulation of receptor crosstalk in innate immunity ⬇️

artículo científico publicado el 1 de marzo de 2011

Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model

article

Modulation of the antitumor immune response by complement

artículo científico publicado en 2008

Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b

artículo científico publicado en 2010

Molecular cloning of the beta subunit of complement component eight of rainbow trout

artículo científico publicado en 2003

Molecular intercommunication between the complement and coagulation systems

artículo científico publicado en 2010

More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation

artículo científico publicado en 2016

Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration

artículo científico publicado en 2013

Multi-scale characterization of the energy landscape of proteins with application to the C3D/Efb-C complex

artículo científico publicado en 2010

Multiple forms of complement C3 in trout that differ in binding to complement activators

artículo científico publicado en 1996

Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation

artículo científico publicado en 2010

Native State of Complement Protein C3d Analysed via Hydrogen Exchange and Conformational Sampling

artículo científico publicado en 2018

Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood

artículo científico publicado en 2011

Neoantigens in complement component C3 as detected by monoclonal antibodies. Mapping of the recognized epitopes by synthetic peptides.

artículo científico publicado en 1990

Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis

artículo científico publicado en 2015

New Analogs of the Complement C3 Inhibitor Compstatin with Increased Solubility and Improved Pharmacokinetic Profile

artículo científico publicado en 2018

New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

artículo científico publicado en 2012

New approaches to the treatment of dense deposit disease

artículo científico publicado en 2007

New insights into the immune functions of complement

scientific article published on 01 August 2019

New milestones ahead in complement-targeted therapy

artículo científico publicado en 2016

Novel Complement Modulators for Paroxysmal Nocturnal Hemoglobinuria: Peptide and Protein Inhibitors of C3 Convertase Prevent Both Surface C3 Deposition and Subsequent Hemolysis of Affected Erythrocytes in Vitro ⬇️

artículo científico publicado en 2012

Novel Immunoassay for Complement Activation by PF4/Heparin Complexes

artículo científico publicado en 2018

Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

artículo científico publicado en 2010

Novel biological networks modulated by complement

artículo científico publicado en 2005

Novel mechanism of antibody-independent complement neutralization of herpes simplex virus type 1.

artículo científico

Novel mechanisms and functions of complement.

artículo científico publicado en 2017

Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays

artículo científico publicado en 2004

Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans

artículo científico publicado en 2011

Overexpression, purification, and characterization of third component of complement

artículo científico publicado en 1994

PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells

artículo científico publicado en 2011

PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer

artículo científico publicado en 2015

Partial hepatectomy induced liver proteome changes in mice

artículo científico publicado en 2005

Pathogenesis of B-cell superantigen-induced immune complex-mediated inflammation

artículo científico publicado en 2006

Pathogenic microbes and community service through manipulation of innate immunity

artículo científico publicado en 2012

Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2014

Peptides of myelin basic protein stimulate T lymphocytes from patients with multiple sclerosis

artículo científico publicado en 1989

Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis

artículo científico publicado en 2017

Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time

artículo científico publicado en 2012

Phylogenetic aspects of the complement system.

artículo científico publicado en 2001

Phylogeny of the third complement component, C3, and conservation of C3-ligand interactions

scientific article published on 01 April 1994

Phylogeny of the third component of complement, C3: Analysis of the conservation of human CR1, CR2, H, and B binding sites, concanavalin A binding sites, and thiolester bond in the C3 from different species

artículo científico publicado en 1992

Physical methods for structure, dynamics and binding in immunological research.

artículo científico publicado en 2004

Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis

artículo científico publicado en 2012

Porphyromonas gingivalis disturbs host-commensal homeostasis by changing complement function

artículo científico publicado en 2017

Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis

artículo científico publicado en 2014

Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood

artículo científico publicado en 2013

Preclinical Development and In Vivo Evaluation Of Next-Generation Compstatin Analogs With Improved Systemic Profiles: A Novel Option For The Treatment Of Paroxysmal Nocturnal Hemoglobinuria ⬇️

artículo científico publicado en 2013

Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood

scientific article published on 08 August 2009

Preformed mediators of defense-Gatekeepers enter the spotlight

artículo científico publicado en 2016

Progress and Trends in Complement Therapeutics ⬇️

artículo científico publicado el 1 de enero de 2013

Prolongation of ex vivo–perfused pig xenograft survival by the complement inhibitor compstatin

scientific article published on 01 February 1999

Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates

scientific article published on 27 March 2020

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

artículo científico publicado en 2002

Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood

artículo científico publicado en 2016

Protection of host cells by complement regulators.

artículo científico publicado en 2016

Protection of innate immunity by C5aR antagonist in septic mice

article

Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine

artículo científico publicado en 2011

Protective Effects of the Complement Inhibitor Compstatin CP40 in Hemorrhagic Shock

Protective effects of IL-6 blockade in sepsis are linked to reduced C5a receptor expression

artículo científico publicado en 2003

Rare loss-of-function mutation in complement component C3 provides insight into molecular and pathophysiological determinants of complement activity

artículo científico publicado en 2015

Rational engineering of a minimized immune inhibitor with unique triple-targeting properties

artículo científico publicado en 2013

Real-time label-free detection of complement activation products in human serum by white light reflectance spectroscopy

artículo científico publicado en 2009

Recent developments in low molecular weight complement inhibitors

artículo científico publicado en 2009

Reduced Terminal Complement Complex Formation in Mice Manifests in Low Bone Mass and Impaired Fracture Healing

artículo científico publicado en 2018

Regulation of Human Cytotoxic Responses by Complement: C3, C3b and C3d Preparations Enhance Human Allogeneic Cytotoxic Responses

artículo científico publicado en 1986

Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation: Points for Therapeutic Interventions

artículo científico

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

artículo científico publicado en 2007

Regulation of immune responsiveness in vivo by disrupting an early T-cell signaling event using a cell-permeable peptide

artículo científico publicado en 2013

Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses

artículo científico publicado en 2017

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

artículo científico publicado en 2016

Restoration of complement-enhanced neutralization of vaccinia virus virions by novel monoclonal antibodies raised against the vaccinia virus complement control protein

artículo científico publicado en 2003

Role of complement in host-microbe homeostasis of the periodontium

artículo científico publicado en 2013

Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting

scientific journal article

Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates.

artículo científico publicado en 2017

Safety profile after prolonged C3 inhibition

scientific article published on 10 October 2018

Segment spanning residues 727-768 of the complement C3 sequence contains a neoantigenic site and accommodates the binding of CR1, factor H, and factor B

scientific article published on 01 February 1992

Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood

artículo científico publicado en 2010

Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients.

artículo científico publicado en 2016

Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

artículo científico publicado en 2021

Short Leucine-Rich Proteoglycans Modulate Complement Activity and Increase Killing of the Respiratory Pathogen

scientific article published on 28 September 2018

Similarities between a conserved sequence element of homoeo boxes and other genes

artículo científico publicado en 1986

Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement

artículo científico publicado en 2020

Solution insights into the structure of the Efb/C3 complement inhibitory complex as revealed by lysine acetylation and mass spectrometry

artículo científico publicado en 2008

Solution structure of Compstatin, a potent complement inhibitor ⬇️

artículo científico publicado el 1 de marzo de 1998

Solvent accessibility of native and hydrolyzed human complement protein 3 analyzed by hydrogen/deuterium exchange and mass spectrometry.

artículo científico publicado en 2005

Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation

artículo científico publicado en 2008

Structural Implications for the Formation and Function of the Complement Effector Protein iC3b.

artículo científico publicado en 2017

Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H.

artículo científico publicado en 1985

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

artículo científico publicado en 2009

Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis.

artículo científico publicado en 1996

Structure and biology of complement protein C3, a connecting link between innate and acquired immunity

artículo científico publicado en 2001

Structure of C3b reveals conformational changes that underlie complement activity

artículo científico publicado en 2006

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators

artículo científico publicado en 2009

Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition

artículo científico publicado en 2007

Structure, functions, and evolution of the third complement component and viral molecular mimicry ⬇️

artículo científico publicado el 1 de enero de 1998

Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin

artículo científico publicado en 2009

Structures of C3b in complex with factors B and D give insight into complement convertase formation

artículo científico publicado en 2010

Studies of structure-activity relations of complement inhibitor compstatin.

artículo científico publicado en 2003

Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration

artículo científico publicado en 2010

Synergistic neuroprotective effects of C3a and C5a receptor blockade following intracerebral hemorrhage

artículo científico publicado en 2009

Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin

artículo científico publicado en 2011

Systems Analysis of the Complement-Induced Priming Phase of Liver Regeneration.

artículo científico publicado en 2016

T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice

artículo científico publicado en 2014

Taming hemodialysis-induced inflammation: Are complement C3 inhibitors a viable option?

artículo científico publicado en 2019

Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis

artículo científico publicado en 2012

Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions

artículo científico publicado en 2020

The C-terminus of complement factor H is essential for host cell protection

artículo científico publicado en 2007

The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss

artículo científico publicado en 2011

The Challenges and Promise of Complement Therapeutics for Ocular Diseases.

artículo científico publicado en 2019

The Complement System Is Critical in Maintaining Retinal Integrity during Aging.

artículo científico publicado en 2018

The XXIV International Complement Workshop (ICW) on October 10-15, 2012. Preface

artículo científico publicado en 2012

The alternative complement pathway regulates pathological angiogenesis in the retina

artículo científico publicado en 2014

The anaphylatoxin receptor C5aR is present during fracture healing in rats and mediates osteoblast migration in vitro

artículo científico publicado en 2011

The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent

artículo científico publicado en 2008

The classical complement cascade mediates CNS synapse elimination

artículo científico publicado en 2007

The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance

artículo científico publicado en 2013

The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo

artículo científico publicado en 2005

The complement system in teleosts

artículo científico publicado en 2002

The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood

artículo científico publicado en 2013

The electrostatic nature of C3d-complement receptor 2 association.

artículo científico publicado en 2004

The evolution and appearance of C3 duplications in fish originate an exclusive teleost c3 gene form with anti-inflammatory activity

artículo científico publicado en 2014

The evolution, structure, biology and pathophysiology of complement

article

The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase

artículo científico publicado en 2014

The first case of COVID-19 treated with the complement C3 inhibitor AMY-101

artículo científico publicado en 2020

The induction of cytokines by polycation containing microspheres by a complement dependent mechanism

artículo científico publicado en 2012

The interaction of glycoprotein C of herpes simplex virus types 1 and 2 with the alternative complement pathway

artículo científico publicado en 1994

The multifunctional role of C3, the third component of complement

artículo científico publicado en 1988

The multifunctional role of C3: Structural analysis of its interactions with physiological ligands

article

The proinflammatory mediators C3a and C5a are essential for liver regeneration

artículo científico publicado en 2003

The regulation of liver cell survival by complement

artículo científico publicado en 2009

The renaissance of complement therapeutics.

artículo científico publicado en 2017

The role of complement in biomaterial-induced inflammation

artículo científico publicado en 2006

The role of complement in inflammatory diseases from behind the scenes into the spotlight

artículo científico publicado en 2007

The role of complement in tumor growth

artículo científico publicado en 2014

The role of properdin in zymosan- and Escherichia coli-induced complement activation

artículo científico publicado en 2012

The role of properdin in zymosan- and Escherichia coli-induced complement activation

artículo científico publicado en 2012

The role of the complement system in metabolic organs and metabolic diseases

artículo científico publicado en 2013

The role of third complement component (C3) in homing of hematopoietic stem/progenitor cells into bone marrow.

artículo científico publicado en 2006

The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR.

artículo científico publicado en 2002

The third component of Xenopus complement: cDNA cloning, structural and functional analysis, and evidence for an alternate C3 transcript.

artículo científico publicado en 1995

The three HveA receptor ligands, gD, LT-alpha and LIGHT bind to distinct sites on HveA.

artículo científico publicado en 2000

Therapeutic C3 inhibitor Cp40 abrogates complement activation induced by modern hemodialysis filters

artículo científico publicado en 2014

Therapeutic control of complement activation at the level of the central component C3.

artículo científico publicado en 2015

Therapeutic targeting of the complement system

scientific article published on 09 December 2019

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin

artículo científico publicado en 2004

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

scientific article published on 26 August 2020

To regeneration...with complement

artículo científico publicado en 2006

Unwelcome complement

artículo científico publicado en 2009

Using an in vitro xenoantibody-mediated complement-dependent cytotoxicity model to evaluate the complement inhibitory activity of the peptidic C3 inhibitor Cp40.

artículo científico publicado en 2015

ciCD94-1, an ascidian multipurpose C-type lectin-like receptor expressed in Ciona intestinalis hemocytes and larval neural structures

artículo científico publicado en 2007

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda