Lista de obras - Dorothy Hudig - Dominio Público Uruguay

A serine proteinase as a "trigger" for human natural killer lymphocyte-mediated cytolysis

artículo científico publicado en 1985

Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide

artículo científico publicado en 1993

Active tumor cell resistance to human natural killer lymphocyte attack

artículo científico publicado en 1981

An improved method to quantify human NK cell-mediated antibody-dependent cell-mediated cytotoxicity (ADCC) per IgG FcR-positive NK cell without purification of NK cells

artículo científico publicado en 2017

Assessment of a role for phospholipase A2 and arachidonic acid metabolism in human lymphocyte natural cytotoxicity.

artículo científico publicado en 1984

Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein

artículo científico publicado en 1996

Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases

scientific article published on 01 November 1993

Calreticulin, a component of the endoplasmic reticulum and of cytotoxic lymphocyte granules, regulates perforin-mediated lysis in the hemolytic model system.

artículo científico publicado en 1998

Cell surface thiols, methylation, and complement-like components are involved in the early events of CML whereas proteases participate in the later, Ca++-dependent events

artículo científico publicado en 1985

Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes)

artículo científico publicado en 1996

Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity

artículo científico publicado en 1994

Conversion of the substrate specificity of mouse proteinase granzyme B ⬇️

artículo científico publicado el 1 de junio de 1994

DNA synthesis and proliferation of human lymphocytes in vitro: III. Fate of cycling cells in aging cultures of phytohemagglutinin stimulated human lymphocytes

scientific article published on 01 January 1981

Definition and redesign of the extended substrate specificity of granzyme B.

artículo científico publicado en 1998

Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C).

artículo científico publicado en 2004

Determination of activable proacrosin/acrosin in bovine sperm using an irreversible isocoumarin serine protease inhibitor

artículo científico publicado en 1996

Dipeptide vinyl sulfones suitable for intracellular inhibition of dipeptidyl peptidase I

scientific journal article

Dipeptidyl peptidase I: importance of progranzyme activation sequences, other dipeptide sequences, and the N-terminal amino group of synthetic substrates for enzyme activity

artículo científico publicado en 2002

Effect of unsaturated fatty acids on human lymphocytes: disparate influences of oleic and linolenic acids on natural cytotoxicity

artículo científico publicado en 1981

Ethanol activation of human natural cytotoxicity ⬇️

artículo científico publicado el 1 de diciembre de 1983

Fluorescent derivatives of diphenyl [1-(N-peptidylamino)alkyl]phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases

artículo científico publicado en 1994

Fractionation of perforin and granzymes by immobilized metal affinity chromatography (IMAC)

artículo científico publicado en 1996

Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease

artículo científico publicado en 2005

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors

artículo científico publicado en 2000

Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes

scientific article published on 01 December 1993

Hydrolysis of tumor cell lipids after CTL-mediated death

artículo científico publicado en 2009

IL-15-mediated induction of LFA-1 is a late step required for cytotoxic differentiation of human NK cells from CD34+Lin- bone marrow cells

artículo científico publicado en 2003

Inclusion of family members without ME/CFS in research studies promotes discovery of biomarkers specific for ME/CFS

scientific article published on 16 June 2020

Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal

artículo científico publicado en 2006

Inhibition of human lymphocyte natural cytotoxicity and antibody-dependent cell-mediated cytotoxicity by K-76 COONa, a reagent that blocks complement activity

artículo científico publicado en 1984

Inhibition of human natural cytotoxicity by macromolecular antiproteases

scientific article published on 01 April 1981

Interaction between a Ca2+-binding protein calreticulin and perforin, a component of the cytotoxic T-cell granules

artículo científico publicado en 1998

Interactions between human natural killer (NK) lymphocytes and yeast cells: human NK cells do not kill Candida albicans, although C. albicans blocks NK lysis of K562 cells

artículo científico publicado en 1988

Lipid-dependent cytotoxicity by the lipase PLRP2 and by PLRP2-positive cytotoxic T lymphocytes (CTLs).

artículo científico publicado en 2009

Localization, implications for function, and gene expression of chymotrypsin-like proteinases of cytotoxic RNK-16 lymphocytes

artículo científico publicado en 1988

Low dose IL-15 induces snap arming of CD44(low) T lymphocytes in the absence of antigen

artículo científico publicado en 2008

Lymphocyte granule-mediated cytolysis requires serine protease activity

scientific article published on 01 December 1987

Lysis by RNK-16 cytotoxic lymphocyte granules. Rate assays and conditions to study control of cytolysis

artículo científico publicado en 1988

NK cells in gamma-interferon-deficient mice suppress lung innate immunity against Mycoplasma spp

artículo científico publicado en 2005

Natural Killer (NK) Cell Expression of CD2 as a Predictor of Serial Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)

artículo científico publicado en 2020

P-4 and RNKP-7, new granzyme-like serine proteases expressed in activated rat lymphocytes

scientific article published on 01 May 1997

Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity

artículo científico publicado en 2009

Perforin lytic activity is controlled by calreticulin

artículo científico publicado en 2000

Perforin-Enhancing Protein, a Low Molecular Weight Protein of Cytotoxic Lymphocyte Granules, Enhances Perforin Lysis ⬇️

artículo científico publicado el 9 de julio de 1997

Properties of human blood monocytes. I. CD91 expression and log orthogonal light scatter provide a robust method to identify monocytes that is more accurate than CD14 expression

artículo científico publicado en 2013

Properties of human blood monocytes. II. Monocytes from healthy adults are highly heterogeneous within and among individuals

artículo científico publicado en 2013

Proteases and lymphocyte cytotoxic killing mechanisms

artículo científico publicado en 1993

Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis ⬇️

artículo científico publicado el 15 de mayo de 1998

RNKP-1, a novel natural killer-associated serine protease gene cloned from RNK-16 cytotoxic lymphocytes.

artículo científico publicado en 1990

Rapid purification of cationic granule proteases: application to human granzymes

artículo científico publicado en 1993

Regulation of perforin lysis: implications for protein disulfide isomerase proteins

artículo científico publicado en 2009

Selective isocoumarin serine protease inhibitors block RNK-16 lymphocyte granule-mediated cytolysis

artículo científico publicado en 1989

Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition

artículo científico publicado en 2008

Sulfonyl fluoride serine protease inhibitors inactivate RNK-16 lymphocyte granule proteases and reduce lysis by granule extracts and perforin ⬇️

artículo científico publicado el 1 de junio de 1992

Synthesis and Kinetic Studies of Diphenyl 1-(N-Peptidylamino)alkanephosphonate Esters and Their Biotinylated Derivatives as Inhibitors of Serine Proteases and Probes for Lymphocyte Granzymes ⬇️

artículo científico publicado el 15 de agosto de 1997

Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase

artículo científico publicado en 1998

Synthetic substrates and inhibitors for serine proteases from lymphocytes, mast cells, semen, and blood

artículo científico publicado el 1 de enero de 1992

The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors

scientific article published on 01 August 1991

The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases

scientific article published on 01 February 1980

The mechanism of cell-mediated cytotoxicity. III. Protease-specific inhibitors preferentially block later events in cytotoxic T lymphocyte-mediated lysis than do inhibitors of methylation or thiol-reactive agents

scientific article published on 01 October 1983

The mechanism of cell-mediated cytotoxicity. IV. K-76 COONa, which inhibits the activity of Factor I and of C5, inhibits early events in cytotoxic T-lymphocyte-mediated cytolysis and in T-lymphocyte activation

artículo científico publicado en 1984

The requirement for proteinase activity for human lymphocyte-mediated natural cytotoxicity (NK): evidence that the proteinase is serine dependent and has aromatic amino acid specificity of cleavage

artículo científico publicado en 1984

cDNA cloning of granzyme J.

artículo científico publicado en 1997

Lista de obras de Dorothy Hudig

A serine proteinase as a "trigger" for human natural killer lymphocyte-mediated cytolysis

Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide

Active tumor cell resistance to human natural killer lymphocyte attack

An improved method to quantify human NK cell-mediated antibody-dependent cell-mediated cytotoxicity (ADCC) per IgG FcR-positive NK cell without purification of NK cells

Assessment of a role for phospholipase A2 and arachidonic acid metabolism in human lymphocyte natural cytotoxicity.

Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein

Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases

Calreticulin, a component of the endoplasmic reticulum and of cytotoxic lymphocyte granules, regulates perforin-mediated lysis in the hemolytic model system.

Cell surface thiols, methylation, and complement-like components are involved in the early events of CML whereas proteases participate in the later, Ca++-dependent events

Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes)

Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity

Conversion of the substrate specificity of mouse proteinase granzyme B ⬇️

DNA synthesis and proliferation of human lymphocytes in vitro: III. Fate of cycling cells in aging cultures of phytohemagglutinin stimulated human lymphocytes

Definition and redesign of the extended substrate specificity of granzyme B.

Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C).

Determination of activable proacrosin/acrosin in bovine sperm using an irreversible isocoumarin serine protease inhibitor

Dipeptide vinyl sulfones suitable for intracellular inhibition of dipeptidyl peptidase I

Dipeptidyl peptidase I: importance of progranzyme activation sequences, other dipeptide sequences, and the N-terminal amino group of synthetic substrates for enzyme activity

Effect of unsaturated fatty acids on human lymphocytes: disparate influences of oleic and linolenic acids on natural cytotoxicity

Ethanol activation of human natural cytotoxicity ⬇️

Fluorescent derivatives of diphenyl [1-(N-peptidylamino)alkyl]phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases

Fractionation of perforin and granzymes by immobilized metal affinity chromatography (IMAC)

Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors

Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes

Hydrolysis of tumor cell lipids after CTL-mediated death

IL-15-mediated induction of LFA-1 is a late step required for cytotoxic differentiation of human NK cells from CD34+Lin- bone marrow cells

Inclusion of family members without ME/CFS in research studies promotes discovery of biomarkers specific for ME/CFS

Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal

Inhibition of human lymphocyte natural cytotoxicity and antibody-dependent cell-mediated cytotoxicity by K-76 COONa, a reagent that blocks complement activity

Inhibition of human natural cytotoxicity by macromolecular antiproteases

Interaction between a Ca2+-binding protein calreticulin and perforin, a component of the cytotoxic T-cell granules

Interactions between human natural killer (NK) lymphocytes and yeast cells: human NK cells do not kill Candida albicans, although C. albicans blocks NK lysis of K562 cells

Lipid-dependent cytotoxicity by the lipase PLRP2 and by PLRP2-positive cytotoxic T lymphocytes (CTLs).

Localization, implications for function, and gene expression of chymotrypsin-like proteinases of cytotoxic RNK-16 lymphocytes

Low dose IL-15 induces snap arming of CD44(low) T lymphocytes in the absence of antigen

Lymphocyte granule-mediated cytolysis requires serine protease activity

Lysis by RNK-16 cytotoxic lymphocyte granules. Rate assays and conditions to study control of cytolysis

NK cells in gamma-interferon-deficient mice suppress lung innate immunity against Mycoplasma spp

Natural Killer (NK) Cell Expression of CD2 as a Predictor of Serial Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)

P-4 and RNKP-7, new granzyme-like serine proteases expressed in activated rat lymphocytes

Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity

Perforin lytic activity is controlled by calreticulin

Perforin-Enhancing Protein, a Low Molecular Weight Protein of Cytotoxic Lymphocyte Granules, Enhances Perforin Lysis ⬇️

Properties of human blood monocytes. I. CD91 expression and log orthogonal light scatter provide a robust method to identify monocytes that is more accurate than CD14 expression

Properties of human blood monocytes. II. Monocytes from healthy adults are highly heterogeneous within and among individuals

Proteases and lymphocyte cytotoxic killing mechanisms

Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis ⬇️

RNKP-1, a novel natural killer-associated serine protease gene cloned from RNK-16 cytotoxic lymphocytes.

Rapid purification of cationic granule proteases: application to human granzymes

Regulation of perforin lysis: implications for protein disulfide isomerase proteins

Selective isocoumarin serine protease inhibitors block RNK-16 lymphocyte granule-mediated cytolysis

Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition

Sulfonyl fluoride serine protease inhibitors inactivate RNK-16 lymphocyte granule proteases and reduce lysis by granule extracts and perforin ⬇️

Synthesis and Kinetic Studies of Diphenyl 1-(N-Peptidylamino)alkanephosphonate Esters and Their Biotinylated Derivatives as Inhibitors of Serine Proteases and Probes for Lymphocyte Granzymes ⬇️

Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase

Synthetic substrates and inhibitors for serine proteases from lymphocytes, mast cells, semen, and blood

The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors

The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases

The mechanism of cell-mediated cytotoxicity. III. Protease-specific inhibitors preferentially block later events in cytotoxic T lymphocyte-mediated lysis than do inhibitors of methylation or thiol-reactive agents

The mechanism of cell-mediated cytotoxicity. IV. K-76 COONa, which inhibits the activity of Factor I and of C5, inhibits early events in cytotoxic T-lymphocyte-mediated cytolysis and in T-lymphocyte activation

The requirement for proteinase activity for human lymphocyte-mediated natural cytotoxicity (NK): evidence that the proteinase is serine dependent and has aromatic amino acid specificity of cleavage

cDNA cloning of granzyme J.