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Antipsychotic drugs regulate hedgehog signaling by modulation of 7-dehydrocholesterol reductase levels

artículo científico publicado en 2010

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.

artículo científico publicado en 2010

Development of mammary tumors by conditional expression of GLI1

scientific article published on 19 May 2009

Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model

artículo científico publicado en 2017

Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis

artículo científico publicado en 2006

Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

scientific journal article

Hedgehog signaling and pancreatic tumor development

artículo científico publicado en 2011

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

artículo científico publicado en 2007

Inhibition of GLI1 gene activation by Patched1

artículo científico publicado en 2006

Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice ⬇️

artículo científico publicado el 31 de agosto de 2011

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

artículo científico publicado en 2007

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

artículo científico

Targeted Expression of GLI1 in the Salivary Glands Results in an Altered Differentiation Program and Hyperplasia ⬇️

artículo científico publicado el 18 de septiembre de 2011

The Hedgehog pathway as a drug target in cancer therapy.

artículo científico publicado en 2007

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition

scholarly article

Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice

artículo científico publicado en 2009

Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes.

artículo científico publicado en 2011

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