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Lista de obras de Kevin M Jude

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

scientific article published on 25 June 2018

A strategy for the selection of monovalent antibodies that span protein dimer interfaces

scientific article published on 06 August 2019

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

artículo científico publicado en 2015

Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins

artículo científico publicado en 2022

Deploying synthetic coevolution and machine learning to engineer protein-protein interactions

artículo científico publicado en 2023

Design of protein-binding proteins from the target structure alone

artículo científico publicado en 2022

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

artículo científico publicado en 2015

Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch

artículo científico publicado en 2020

Oxyanion-mediated inhibition of serine proteases

artículo científico publicado en 1998

Real-time detection of DNA topological changes with a fluorescently labeled cruciform.

artículo científico publicado en 2013

Receptor subtype discrimination using extensive shape complementary designed interfaces

scientific article published on 13 May 2019

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

artículo científico publicado en 2018

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.

artículo científico publicado en 2018

Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II

artículo científico publicado en 2007

Structural biology. Structural basis for Notch1 engagement of Delta-like 4

artículo científico publicado en 2015

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

artículo científico publicado en 2015

Structure of a 129 Xe-Cryptophane Biosensor Complexed with Human Carbonic Anhydrase II

artículo científico publicado en 2008

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling

artículo científico publicado en 2020

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

artículo científico publicado en 2019

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

artículo científico publicado en 2018

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