Lista de obras - Scott B Rothbart - Dominio Público Uruguay

A DNA methylation reader complex that enhances gene transcription

artículo científico publicado en 2018

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin

artículo científico publicado en 2015

A fast, open source implementation of adaptive biasing potentials uncovers a ligand design strategy for the chromatin regulator BRD4. ⬇️

artículo científico publicado en 2016

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

artículo científico publicado en 2018

A histone methylation network regulates transgenerational epigenetic memory in C. elegans

artículo científico publicado en 2014

A physical basis for quantitative ChIP-sequencing

artículo científico publicado en 2020

AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells

artículo científico publicado en 2015

An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.

artículo científico publicado en 2015

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

artículo científico publicado en 2013

An Interactive Database for the Assessment of Histone Antibody Specificity

artículo científico publicado en 2015

An acetyl-methyl switch drives a conformational change in p53.

artículo científico publicado en 2015

Analysis of Histone Antibody Specificity with Peptide Microarrays

artículo científico

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

artículo científico publicado en 2012

Chromatin biochemistry enters the next generation of code 'seq-ing'.

artículo científico publicado en 2014

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

article published in the Proceedings of the National Academy of Sciences of the United States of America

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance

artículo científico publicado en 2018

Dido3 PHD Modulates Cell Differentiation and Division

artículo científico publicado en 2013

From histones to ribosomes: a chromatin regulator tangoes with translation

artículo científico publicado en 2015

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

artículo científico publicado en 2016

Histone H3.3 phosphorylation amplifies stimulation-induced transcription

artículo científico publicado en 2020

Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions

artículo científico publicado en 2017

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function

scientific article published on 22 February 2014

Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.

artículo científico publicado en 2015

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

scientific article published on 11 December 2020

Interpreting the language of histone and DNA modifications

artículo científico

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes

artículo científico publicado en 2015

Molecular basis for chromatin binding and regulation of MLL5

artículo científico publicado en 2013

Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation

artículo científico publicado en 2013

Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation

artículo científico publicado en 2015

Pemetrexed Indirectly Activates the Metabolic Kinase AMPK in Human Carcinomas ⬇️

artículo científico publicado el 15 de diciembre de 2010

Peptide microarrays to interrogate the "histone code".

artículo científico publicado en 2012

Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies

artículo científico publicado en 2012

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

scientific article published on 17 October 2016

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF

scientific article published on 24 May 2019

Structural basis for DNMT3A-mediated de novo DNA methylation

artículo científico publicado en 2018

Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1

artículo científico publicado en 2015

Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue

artículo científico publicado en 2013

Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq

artículo científico publicado en 2016

Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin

artículo científico publicado en 2012

The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer

artículo científico publicado en 2017

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

artículo científico publicado en 2019

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells

artículo científico publicado en 2020

Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition

artículo científico publicado en 2009

Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner

scientific article published on 05 February 2019

Lista de obras de Scott B Rothbart

A DNA methylation reader complex that enhances gene transcription

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin

A fast, open source implementation of adaptive biasing potentials uncovers a ligand design strategy for the chromatin regulator BRD4. ⬇️

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

A histone methylation network regulates transgenerational epigenetic memory in C. elegans

A physical basis for quantitative ChIP-sequencing

AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells

An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

An Interactive Database for the Assessment of Histone Antibody Specificity

An acetyl-methyl switch drives a conformational change in p53.

Analysis of Histone Antibody Specificity with Peptide Microarrays

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

Chromatin biochemistry enters the next generation of code 'seq-ing'.

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance

Dido3 PHD Modulates Cell Differentiation and Division

From histones to ribosomes: a chromatin regulator tangoes with translation

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

Histone H3.3 phosphorylation amplifies stimulation-induced transcription

Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function

Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Interpreting the language of histone and DNA modifications

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes

Molecular basis for chromatin binding and regulation of MLL5

Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation

Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation

Pemetrexed Indirectly Activates the Metabolic Kinase AMPK in Human Carcinomas ⬇️

Peptide microarrays to interrogate the "histone code".

Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF

Structural basis for DNMT3A-mediated de novo DNA methylation

Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1

Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue

Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq

Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin

The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells

Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition

Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner