161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS
artículo científico publicado en 2018
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
artículo científico publicado en 2016
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016
artículo científico publicado en 2016
4-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood T cells against B-cell malignancies
artículo científico publicado en 2010
<i>Salmonella</i>-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy
artículo científico publicado en 2020
A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial
artículo científico publicado en 2015
A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing
artículo científico publicado en 2016
A Model System for Visualization of Whole-Body Sdf-1 Expression During Hematopoietic Cell Transplant.
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artículo científico publicado en 2009
A Novel Triple Umbilical Cord Blood Transplant (UCBT) Strategy To Promote NK Cell Immunotherapy (Unit 1) with a Fully Ablative Preparative Regimen Followed by a Double UCBT in Patients with Refractory AML.
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artículo científico publicado en 2006
A Phase I study of granulocyte-macrophage-colony stimulating factor/interleukin-3 fusion protein (PIXY321) following ifosfamide, carboplatin, and etoposide therapy for children with recurrent or refractory solid tumors
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artículo científico publicado el 1 de octubre de 1998
A Phase II Study Of Proteasome-Inhibition For Initial Therapy Of Chronic Graft-Versus-Host Disease
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artículo científico publicado en 2013
A Randomized Trial of One Vs. Two Doses of Influenza Vaccine Following Allogeneic Transplantation
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artículo científico publicado en 2012
A Refined Clinical Risk Score at Onset of Treatment for Acute Gvhd That Predicts Response to Initial Therapy, Survival and Transplant-Related Mortality
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artículo científico publicado en 2014
A Selective and Potent Rock 2 Inhibitor (KD025) Decreases Human STAT3-Dependent IL-21 and IL-17 Production and Experimental Chronic Graft-Versus-Host Disease (cGVHD)
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scholarly article
A confirmation of chronic graft-versus-host disease prediction using allogeneic HY antibodies following sex-mismatched hematopoietic cell transplantation
scientific article published on 17 January 2019
A correlation between conditioning and engraftment in recipients of MHC-mismatched T cell-depleted murine bone marrow transplants
scientific article published on 01 August 1985
A critical role for CD48 antigen in regulating alloengraftment and lymphohematopoietic recovery after bone marrow transplantation
artículo científico publicado en 1998
A critical role for donor-derived IL-22 in cutaneous chronic GVHD.
artículo científico publicado en 2017
A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells
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artículo científico publicado el 1 de octubre de 1995
A new murine model for bronchiolitis obliterans post-bone marrow transplant
artículo científico publicado en 2007
A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression.
artículo científico publicado en 2018
A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity
artículo científico publicado en 2007
A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells
artículo científico publicado en 2004
A phase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease
artículo científico publicado en 2007
A phase I clinical, pharmacological, and biological trial of interleukin 6 plus granulocyte-colony stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent/refractory solid tumors: enhanced hematological [...]
artículo científico publicado en 2001
A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group
artículo científico publicado en 1997
A phase II study of bortezomib plus prednisone for initial therapy of chronic graft-versus-host disease
artículo científico publicado en 2014
A phase II trial of human recombinant interleukin-2 administered as a 4-day continuous infusion for children with refractory neuroblastoma, non-Hodgkin's lymphoma, sarcoma, renal cell carcinoma, and malignant melanoma. A Childrens Cancer Group study
artículo científico publicado en 1995
A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system
artículo científico publicado en 2005
A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer
artículo científico publicado en 2012
A randomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease
artículo científico publicado en 2000
A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation
artículo científico publicado en 2012
A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality
artículo científico publicado en 2015
A robust in vitro model for trans-lymphatic endothelial migration
artículo científico publicado en 2017
A substantial level of donor hematopoietic chimerism is required to protect donor-specific islet grafts in diabetic nod mice
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artículo científico publicado el 15 de abril de 2003
A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells
artículo científico publicado en 2020
ARID5B regulates metabolic programming in human adaptive NK cells.
artículo científico publicado en 2018
Abnormal T cell-dependent B-cell responses in SCID mice receiving allogeneic bone marrow in utero. Severe combined immune deficiency
scientific article published on 08 August 2002
Abnormal function of the bone marrow microenvironment in chronic myelogenous leukemia: role of malignant stromal macrophages.
artículo científico publicado en 1995
Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
scientific article published on 17 July 2019
Absence of a facilitory role for NK 1.1-positive donor cells in engraftment across a major histocompatibility barrier in mice
scientific article published on 01 May 1988
Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome
artículo científico publicado en 2004
Acceleration of idiopathic pneumonia syndrome (IPS) in the absence of donor MIP-1 alpha (CCL3) after allogeneic BMT in mice
artículo científico publicado en 2003
Achievement of Tolerance Induction to Prevent Acute Graft-vs.-Host Disease
article published in 2019
Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease
artículo científico publicado en 2010
Activated Alveolar Macrophage-Derived Nitric Oxide Predicts the Development of Lung Damage After Marrow Transplantation in Mice
article
Activated Protein C (APC) Therapy Ameliorates Chronic Graft Versus Host Disease By Cell Signaling Mechanisms That Require Cleavage at Arg46 in PAR1 on T Cells
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scholarly article
Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells
artículo científico publicado en 2019
Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors
artículo científico publicado en 2018
Activation of thymic regeneration in mice and humans following androgen blockade
artículo científico publicado en 2005
Acute Graft-Versus-Host Disease: Clinical Presentation and Response to Therapy Following Umbilical Cord Blood Transplant.
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artículo científico publicado en 2004
Acute Graft-versus-Host Disease
scientific article published on 01 February 2018
Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy
artículo científico publicado en 2017
Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors
artículo científico publicado en 2008
Acute graft-versus-host disease following unrelated donor marrow transplantation: failure of conventional therapy
artículo científico publicado el 1 de julio de 1992
Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome.
artículo científico publicado en 2017
Acute graft-versus-host disease: from the bench to the bedside
artículo científico publicado en 2009
Acute toxicity of CD40 stimulation following syngeneic bone marrow transplantation
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artículo científico publicado en 2000
Acute upper gastrointestinal graft-versus-host disease: clinical significance and response to immunosuppressive therapy.
artículo científico
Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.
artículo científico publicado en 2018
Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells
artículo científico publicado en 2016
Adaptive NK cell reconstitution is associated with better clinical outcomes
scholarly article by Frank Cichocki et al published 24 January 2019 in JCI insight
Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Tr
artículo científico publicado en 2015
Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival
artículo científico publicado en 2006
Adenosine receptor A2A deficiency in leukocytes increases arterial neointima formation in apolipoprotein E-deficient mice
artículo científico publicado en 2010
Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice
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scholarly article
Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice
artículo científico publicado en 2014
Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.
artículo científico publicado en 2002
Adoptive Transfer of Umbilical Cord Blood-Derived Regulatory T Cells and Early Viral Reactivation
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artículo científico publicado el 25 de junio de 2013
Adult bone marrow-derived pluripotent hematopoietic stem cells are engraftable when transferred in utero into moderately anemic fetal recipients.
artículo científico publicado en 1995
Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation
artículo científico publicado en 2015
Advances in graft-versus-host disease biology and therapy
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artículo científico publicado el 11 de mayo de 2012
Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy
artículo científico publicado en 2017
Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy
artículo científico publicado en 2013
Allogeneic bone marrow transplantation for X-linked lymphoproliferative syndrome
scientific article published on 01 August 1986
Allogenic fetal liver cells have a distinct competitive engraftment advantage over adult bone marrow cells when infused into fetal as compared with adult severe combined immunodeficient recipients
scientific article published on 01 March 2002
Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration
artículo científico publicado en 2004
Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death.
artículo científico publicado en 2018
Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease
artículo científico publicado en 2009
Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease
artículo científico publicado en 2001
Alternate Donor HSCT for Fanconi Anemia (FA): Results of a Total Body Irradiation (TBI) Dose De-Escalation Study.
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artículo científico publicado en 2007
Alternative Donor Hematopoietic Cell Transplantation In 94 Patients with Fanconi Anemia at the University of Minnesota
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scholarly article
Alternative donor hematopoietic cell transplantation for Fanconi anemia
artículo científico publicado en 2015
Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells
scientific article published on 27 October 2008
Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid
scientific article published on 13 November 2018
Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802
article
An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.
artículo científico publicado en 2017
An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease
artículo científico publicado en 2004
An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition
artículo científico publicado en 2017
An alpha-defensin gene single nucleotide polymorphism modulates the gut microbiota and may alter the risk of acute graft-versus-host disease
scientific article published on 21 February 2020
An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos.
artículo científico publicado en 2013
An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin
artículo científico publicado en 2021
Analysis of BMT CTN-0201 and -0901 samples did not reproduce the reported association between recipient REG3A rs7588571 and chronic GVHD
artículo científico publicado en 2018
Analysis of the requirements for the induction of CD4+ T cell alloantigen hyporesponsiveness by ex vivo anti-CD40 ligand antibody
artículo científico publicado en 2000
Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation
artículo científico publicado en 2005
Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology
artículo científico publicado en 2016
Anti-CD3 + IL-2-stimulated murine killer cells. In vitro generation and in vivo antitumor activity
artículo científico publicado en 1989
Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen
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artículo científico publicado el 15 de diciembre de 1997
Anti-CD3 immunotoxin prevents low-dose STZ/interferon-induced autoimmune diabetes in mouse
artículo científico publicado en 1992
Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.
artículo científico publicado en 1996
Antibodies targeting surface membrane antigens in patients with chronic graft-versus-host disease
artículo científico publicado en 2017
Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation
artículo científico publicado en 2001
Antitumor protection from the murine T-cell leukemia/lymphoma EL4 by the continuous subcutaneous coadministration of recombinant macrophage-colony stimulating factor and interleukin-2
artículo científico publicado en 1993
Anti–PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation
artículo científico publicado en 2024
Assessment of multi-organ system engraftment by genotypic typing using restriction fragment-length polymorphisms and by phenotypic typing using a microcytotoxicity assay
artículo científico publicado en 1986
Association between recipient TNF rs361525 and acute GVHD: results from analysis of BMT CTN-0201 samples
scientific article published on 07 March 2018
Attenuation of acute graft-versus-host disease in the absence of the transcription factor RORγt
artículo científico publicado en 2012
Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo
scientific article published on 01 May 2001
Augmentation of donor bone marrow engraftment in histoincompatible murine recipients by granulocyte/macrophage colony-stimulating factor
artículo científico publicado en 1988
Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity
artículo científico publicado en 2020
Autologous bone marrow transplantation in acute myeloid leukemia: the University of Minnesota experience
artículo científico publicado en 1996
Autologous bone marrow versus non-mobilized peripheral blood stem cell transplantation for lymphoid malignancies: a prospective, comparative trial
scientific article published on 01 March 1997
Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.
artículo científico publicado en 2016
B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.
artículo científico publicado en 2017
B cell induction of IL-13 expression in NK cells: role of CD244 and SLAM-associated protein
artículo científico publicado en 2006
B cells in chronic graft-versus-host disease
artículo científico publicado en 2015
B-cell targeting in chronic Graft-versus-Host disease
artículo científico publicado en 2018
B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections].
artículo científico publicado en 2004
B7-1 expression decreases tumorigenicity and induces partial systemic immunity to murine neuroblastoma deficient in major histocompatibility complex and costimulatory molecules
artículo científico publicado en 1995
B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality
artículo científico publicado en 2015
Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs
scientific article published on 19 August 2019
Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation
scientific article published on 01 January 1997
Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease
artículo científico publicado en 2002
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism
artículo científico publicado en 2003
Blockade of the CD40/CD154 pathway enhances T-cell-depleted allogeneic bone marrow engraftment under nonmyeloablative and irradiation-free conditioning therapy
artículo científico publicado en 2003
Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes
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artículo científico publicado el 10 de noviembre de 2011
Bone Marrow Myeloid-Derived Suppressor Cells (MDSC) Inhibit Graft Versus Host Disease (GVHD) Via An Arginase-1 Dependant Mechanism That Is Upregulated by IL-13
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scholarly article
Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease Control
artículo científico publicado en 2021
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13
artículo científico publicado en 2010
Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression
artículo científico publicado en 2013
Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD).
artículo científico publicado en 2005
Bone marrow transplantation for recessive dystrophic epidermolysis bullosa
artículo científico publicado en 2010
Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation
artículo científico publicado en 2012
Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results
artículo científico publicado en 2018
Busulfan disposition in children
artículo científico publicado en 1990
Busulfan pharmacokinetics do not predict relapse in acute myeloid leukemia
scientific article published on 01 September 2000
Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help
artículo científico publicado en 2014
C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans
CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease
artículo científico publicado en 2013
CCR1 Is Required for Treg-Mediated Protection From Lethal Acute Graft-Versus-Host Disease.
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artículo científico publicado en 2009
CD154 on the surface of CD4+CD25+ regulatory t cells contributes to skin transplant tolerance
artículo científico publicado en 2003
CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets
artículo científico publicado en 2014
CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates
CD28 costimulation is essential for human T regulatory expansion and function
artículo científico publicado en 2008
CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells
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artículo científico publicado el 1 de octubre de 1997
CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease
scientific article published on 01 September 2004
CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration
artículo científico publicado en 2019
CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses
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artículo científico publicado el 1 de agosto de 1998
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
artículo científico publicado en 2001
CD4+ and CD8+ T cells each can utilize a perforin-dependent pathway to mediate lethal graft-versus-host disease in major histocompatibility complex-disparate recipients
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artículo científico publicado el 27 de agosto de 1997
CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy
artículo científico publicado en 2005
CD4+CD25+Foxp3+ Regulatory T Cell Function Outside the Immune System: Differential Regulation of Hematopoietic Progenitor Cell Populations.
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artículo científico publicado en 2007
CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation
CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells
artículo científico publicado en 2001
CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis
artículo científico publicado en 2014
CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire
artículo científico publicado en 2015
CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression.
artículo científico publicado en 2018
CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa
artículo científico publicado en 2016
CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.
artículo científico publicado en 2014
Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT
artículo científico publicado en 2017
Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies
artículo científico publicado en 2010
Cardiac functional and histopathologic findings in humans and mice with mucopolysaccharidosis type I: implications for assessment of therapeutic interventions in hurler syndrome
artículo científico publicado en 2005
Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells
artículo científico publicado en 2016
Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice
artículo científico publicado en 2014
Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype
artículo científico publicado en 2010
Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Nonhuman Primates
scientific article published on 21 March 2018
Chimeric antigen receptor costimulation domains modulate human regulatory T cell function.
artículo científico publicado en 2019
Chronic GvHD Is Characterized By Impaired B Cell Development in the Bone Marrow
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artículo científico publicado en 2015
Chronic graft-versus-host disease: biological insights from preclinical and clinical studies
artículo científico publicado en 2016
Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming
artículo científico publicado en 2019
Circulating T follicular helper cells with increased function during chronic graft-versus-host disease
artículo científico publicado en 2016
Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802
artículo científico publicado en 2015
Circulating macrophage colony-stimulating factor is not reduced in malignant osteopetrosis
artículo científico publicado el 1 de enero de 1992
Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
artículo científico publicado en 2014
Clinical application of expanded CD4+25+ cells
artículo científico publicado en 2006
Clinical perspectives for regulatory T cells in transplantation tolerance
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artículo científico publicado el 5 de agosto de 2011
Clinical-scale selection of anti-CD3/CD28-activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor
artículo científico publicado en 2002
Coblockade of the LFA1:ICAM and CD28/CTLA4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts
scientific article published on 01 May 1995
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
artículo científico publicado en 2011
Combination graft-versus-host disease prophylaxis using immunotoxin (anti-CD5-RTA [Xomazyme-CD5]) plus methotrexate and cyclosporine or prednisone after unrelated donor marrow transplantation
artículo científico publicado en 1993
Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses
artículo científico publicado en 2008
Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant
artículo científico publicado en 2017
Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions
artículo científico publicado en 2002
Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses
artículo científico publicado en 2002
Comparison of engraftment in recipients of matched sibling of unrelated donor marrow allografts
scientific article published on 01 January 1994
Comparison of enzymatic activity with evidence of engraftment in patients with inborn errors of metabolism receiving allogeneic marrow transplantation
artículo científico publicado en 1986
Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation
artículo científico publicado en 2015
Concise review: Transplantation of human hematopoietic cells for extracellular matrix protein deficiency in epidermolysis bullosa
artículo científico publicado en 2011
Concise review: hitting the right spot with mesenchymal stromal cells
artículo científico publicado en 2010
Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses
artículo científico publicado en 2010
Continuous IL-15 Signaling Leads to Functional Exhaustion of Human Natural Killer Cells through Metabolic Changes That Alters Their In Vivo Anti-Tumor Activity
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scholarly article
Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect
artículo científico publicado en 2018
Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells
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artículo científico publicado el 7 de junio de 2012
Control of acute myeloid leukemia relapse--dance between KIRs and HLA
scientific article published on 01 August 2012
Cooking Up Tolerance: Has a New Recipe Been Created?
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artículo científico publicado el 15 de junio de 2012
Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells.
artículo científico publicado en 2006
Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
artículo científico publicado en 2004
Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery
artículo científico publicado en 2007
Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation
artículo científico publicado en 2006
Correction of the Skin Defect in Murine Recessive Dystrophic Epidermolysis Bullosa by Bone Marrow Derived SLAM Family Receptor Enriched Cells.
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artículo científico publicado en 2007
Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells
artículo científico publicado en 2018
Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD.
artículo científico publicado en 2016
CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma
artículo científico publicado en 2003
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease
artículo científico publicado en 2005
Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol
artículo científico publicado en 2019
Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets
artículo científico publicado en 2018
Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade
artículo científico publicado en 2015
Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease
artículo científico publicado en 1999
Cyclophosphamide prevents systemic keratinocyte growth factor-induced up-regulation of surfactant protein A after allogeneic transplant in mice
artículo científico publicado en 2000
Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: influence of mouse colony environment.
artículo científico publicado en 1998
Cytokine expression in human cutaneous chronic graft-versus-host disease
artículo científico publicado en 1996
Cytokine mediators of chronic graft-versus-host disease
artículo científico publicado en 2017
Cytokine-primed bone marrow stem cells vs. peripheral blood stem cells for autologous transplantation: a randomized comparison of GM-CSF vs. G-CSF
artículo científico publicado el 1 de octubre de 1997
Cytolytic CD4+ and CD8+ Regulatory T-Cells and Implications for Developing Immunotherapies to Combat Graft-Versus-Host Disease
artículo científico publicado en 2022
Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion
artículo científico publicado en 2008
DNA Methylation Profile of Runx1 Regulatory Regions Is Correlated with Transition From Primitive to Definitive Hematopoietic Potential In Vitro and In Vivo
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scholarly article
DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo
artículo científico publicado en 2013
Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD
scientific article published on 01 November 2019
Death Receptor 3 (DR3) Is Expressed By Innate Lymphoid Cells (ILC) and Ligation By Tumor Like Antigen-1 (TL1A) Leads To Costimulation and Significant ILC Expansion
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artículo científico publicado en 2013
Defective Neo-Antigen Response to Keyhole Limpet Hemocyanin (KLH) Vaccines in Patients after Hematopoietic Cell Transplantation.
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artículo científico publicado en 2004
Defining Successful Immune Reconstitution (IR) after Allogeneic Hematopoietic Cell Transplantation (HCT)
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artículo científico publicado en 2015
Defining the Primate GvHD Transcriptome: Network Analysis Identifies the Key Pathways Responsible for GvHD Pathogenesis and the Mechanisms of Partial GvHD Control with Sirolimus
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artículo científico publicado en 2012
Defining the Primate T Cell Transcriptome during Graft Versus Host Disease: New Data Implicating the Hedgehog and Aurora Kinase Pathways in Pathogenesis and Prevention
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artículo científico publicado en 2014
Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD
artículo científico publicado en 2018
Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy
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artículo científico publicado el 17 de enero de 2012
Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation
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scholarly article
Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease
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artículo científico publicado en 2014
Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality
scientific article published on 18 March 2019
Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway.
artículo científico publicado en 2008
Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses
artículo científico publicado en 2006
Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia
scientific article published on 01 May 1995
Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia
artículo científico publicado en 2009
Depressed leukocyte reconstitution and engraftment in murine recipients of T cell-depleted histoincompatible marrow pretreated with interleukin 3
artículo científico publicado en 1988
Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.
artículo científico publicado en 2018
Development of IL-22-producing NK lineage cells from umbilical cord blood hematopoietic stem cells in the absence of secondary lymphoid tissue
artículo científico publicado en 2011
Development of a decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded
artículo científico publicado en 2010
Differential Regulation of T-cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node
scientific article published on 01 October 2019
Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets
scientific article published on 06 June 2019
Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity
artículo científico publicado en 2005
Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice
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artículo científico publicado el 1 de noviembre de 1998
Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy
artículo científico publicado en 2017
Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning
artículo científico publicado en 2004
Difficult stem cell mobilization despite adequate CD34+ cell dose predicts shortened progression free and overall survival after autologous HSCT for lymphoma
artículo científico publicado en 2007
Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation
artículo científico publicado en 2005
Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing
Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD
scientific article published on 20 April 2020
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
artículo científico publicado en 2018
Distinct Regulatory and Effector T Cell Metabolic Demands during Graft-Versus-Host Disease
scientific article published on 30 November 2019
Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ
artículo científico publicado en 2004
Divergent fates of antigen-specific CD8<sup>+</sup> T cell clones in mice with acute leukemia
artículo científico publicado en 2021
Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans
artículo científico publicado en 2011
Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice
artículo científico publicado en 2014
Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease
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scholarly article
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.
artículo científico publicado en 2009
Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality
scientific article published on 03 October 2019
Donor and host influences in bone marrow transplantation for immunodeficiency disease and leukemia
artículo científico publicado en 1993
Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402.
artículo científico publicado en 2017
Donor chimerism does not predict response to donor lymphocyte infusion for relapsed chronic myelogenous leukemia after allogeneic hematopoietic cell transplantation
artículo científico publicado en 2004
Dose and timing of interleukin (IL)-12 and timing and type of total-body irradiation: effects on graft-vs.-host disease inhibition and toxicity of exogenous IL-12 in murine bone marrow transplant recipients
scientific article published on 01 January 1999
Dose-escalated interleukin-2 therapy for refractory chronic graft-versus-host disease in adults and children
artículo científico publicado en 2019
Dynamic Graft-versus-Host Disease-Free, Relapse-Free Survival: Multistate Modeling of the Morbidity and Mortality of Allotransplantation
artículo científico publicado en 2019
Early E. casseliflavus gut colonization and outcomes of allogeneic hematopoietic cell transplantation
artículo científico publicado en 2019
Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease
scientific article published on 10 June 2019
Early antithymocyte globulin therapy improves survival in patients with steroid-resistant acute graft-versus-host disease
artículo científico publicado en 2002
Effect of IL-7 or IL-4 on reconstitution of donor lymphoid cells in congenic murine bone marrow transplantation
artículo científico publicado el 1 de julio de 1995
Effect of radiation dose-rate on hematopoietic cell engraftment in adult zebrafish
artículo científico publicado en 2013
Effect of recombinant human macrophage colony-stimulating factor in irradiated murine recipients of T-cell-depleted allogeneic or non-depleted syngeneic bone marrow transplants
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artículo científico publicado el 15 de marzo de 1992
Effect of tumor necrosis factor alpha and of the soluble tumor necrosis factor receptor on insulin secretion of isolated islets of Langerhans
artículo científico publicado en 1992
Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning
scientific article published on 08 February 2020
Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-gamma
scientific article published on 01 March 1996
Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.
artículo científico publicado en 2011
Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necro
artículo científico publicado en 2005
Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease
artículo científico publicado en 2018
Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells
artículo científico publicado en 2008
Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation
artículo científico publicado en 2001
Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease
article published in 2019
Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease
artículo científico publicado en 2016
Elevation of intracellular cyclic AMP in alloreactive CD4(+) T Cells induces alloantigen-specific tolerance that can prevent GVHD lethality in vivo
artículo científico publicado en 2007
Embryonic pig pancreatic tissue transplantation for the treatment of diabetes
artículo científico publicado en 2006
Emerging strategies to boost thymic function
artículo científico publicado en 2010
Endogenous IL-2 production by natural killer cells maintains cytotoxic and proliferative capacity following retroviral-mediated gene transfer
artículo científico publicado el 1 de octubre de 1997
Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin
artículo científico publicado en 2004
Engineered IL-2 Cytokine-Cytokine Receptor Complex Enables Selective Expansion of Regulatory T Cells and Facilitates Establishment of Organ Transplantation Tolerance
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artículo científico publicado en 2020
Engineering lymphocyte subsets: tools, trials and tribulations
artículo científico publicado en 2009
Engraftment of severe combined immune deficient mice receiving allogeneic bone marrow via In utero or postnatal transfer.
artículo científico publicado en 1998
Enhanced survival but reduced engraftment in murine recipients of recombinant granulocyte/macrophage colony-stimulating factor following transplantation of T-cell-depleted histoincompatible bone marrow
scientific article published on 01 October 1988
Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.
artículo científico publicado en 2017
Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation
artículo científico publicado en 1988
Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells
artículo científico publicado en 2018
Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival
artículo científico publicado en 2017
Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor
scientific article published on 05 July 2002
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases
artículo científico publicado en 2015
Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer
artículo científico publicado en 2016
Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.
artículo científico publicado en 2011
Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation
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artículo científico publicado el 2 de octubre de 2003
Ex vivo fucosylation of third-party human regulatory T cells enhances anti-graft-versus-host disease potency in vivo
artículo científico publicado en 2014
Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease.
artículo científico publicado en 2009
Expanded nonhuman primate tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses
artículo científico publicado en 2008
Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in vivo cytokine administration: implications for clinical therapy
artículo científico publicado en 2014
Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio
artículo científico publicado en 2009
Exuberant inflammation in nicotinamide adenine dinucleotide phosphate-oxidase-deficient mice after allogeneic marrow transplantation
artículo científico publicado en 2002
FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation.
artículo científico publicado en 1996
FK506 inhibits graft-versus-host disease and bone marrow graft rejection in murine recipients of MHC disparate donor grafts by interfering with mature peripheral T cell expansion post-transplantation
artículo científico publicado en 1994
FLT3 ligand administration after hematopoietic cell transplantation increases circulating dendritic cell precursors that can be activated by CpG oligodeoxynucleotides to enhance T-cell and natural killer cell function
artículo científico publicado en 2005
FTY720 Markedly Increases Alloengraftment but Does Not Eliminate Host Anti-Donor T Cells that Cause Graft Rejection on Its Withdrawal
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artículo científico publicado el 19 de junio de 2012
FTY720 Promotes Engraftment of Allogeneic Donor Bone Marrow Stem Cells but Impairs Thymopoiesis Resulting in Delayed Graft Rejection.
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artículo científico publicado en 2009
Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor
scientific article published on 01 April 2020
Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation
artículo científico publicado en 2001
Factors predicting single-unit predominance after double umbilical cord blood transplantation
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artículo científico publicado el 26 de septiembre de 2011
Fanconi anemia gene editing by the CRISPR/Cas9 system
artículo científico publicado en 2015
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
artículo científico publicado en 2017
First Use of Allogeneic Stem Cells in the Treatment of Recessive Dystrophic Epidermolysis Bullosa: Demonstration of Biochemical and Clinical Improvement.
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artículo científico publicado en 2009
First-in-human Phase 1 Clinical Study of the IL-15 Superagonist Complex ALT-803 to Treat Relapse after Transplantation
artículo científico publicado en 2018
First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia
scientific article published on 01 July 2019
Flt3 ligand (FL) treatment of murine donors does not modify graft-versus-host disease (GVHD) but FL treatment of recipients post-bone marrow transplantation accelerates GVHD lethality
artículo científico publicado en 2001
Flt3 ligand antitumor activity in a murine breast cancer model: a comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action
artículo científico publicado en 1999
Fludarabine vs cladribine plus busulfan and low-dose TBI as reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation: a prospective randomized trial
artículo científico publicado en 2007
Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses
artículo científico publicado en 2019
Follistatin and Soluble Endoglin Predict 1-Year Nonrelapse Mortality after Allogeneic Hematopoietic Cell Transplantation
artículo científico publicado en 2019
FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program
scientific article published on 31 January 2019
Functional NK cell repertoires are maintained through IL-2Rα and Fas ligand.
artículo científico publicado en 2014
GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells
artículo científico publicado en 2020
GM-CSF-induced internal autocrine proliferation occurs in a compartment outside of the endoplasmic reticulum
artículo científico publicado el 1 de julio de 1995
GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity
artículo científico publicado en 2017
GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28− CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression
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artículo científico publicado el 10 de septiembre de 2010
GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.
artículo científico publicado en 2016
GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.
artículo científico publicado en 2015
Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation
artículo científico publicado en 2001
Gender-related dimorphism in aortic insufficiency in murine mucopolysaccharidosis type I
artículo científico publicado en 2009
Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor--immunotoxin target gene
artículo científico publicado en 2002
General strategies in in vivo animal modeling
artículo científico publicado el 1 de enero de 1992
Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells
artículo científico publicado en 2019
Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease
artículo científico publicado en 2011
Genetic trickery--escape of leukemia from immune attack
scientific article published on 01 July 2009
Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model
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artículo científico publicado en 2013
Glucagon like peptide-2 for Intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans
artículo científico publicado en 2020
Graft Versus Host Disease After Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management
artículo científico publicado en 2016
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia
scientific article published on 01 March 2020
Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings. A pilot study using immunotoxins for T cell depletion of donor bone marrow
scientific article published on 01 July 1987
GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression
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artículo científico publicado en 2010
Haploidentical Natural Killer (NK) Cells Expanding In Vivo After Adoptive Transfer Exhibit Hyperfunction That Partially Overcomes Self Tolerance and Leads to Clearance of Refractory Leukemia
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artículo científico publicado en 2011
Haploidentical Natural Killer Cell Infusion Induces Remission in Non-Hodgkin Lymphoma and Overcomes Resistance to Rituximab
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scholarly article
Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells
artículo científico publicado en 2017
Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells
article
Hematopoietic cell therapy for metabolic disease
artículo científico publicado en 2007
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome)
artículo científico publicado en 2010
Hematopoietic progenitor cell regulation by CD4+CD25+ T cells
artículo científico publicado en 2010
Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells
artículo científico publicado en 2007
Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.
artículo científico publicado en 2007
High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation
artículo científico publicado en 1999
Higher therapeutic CsA levels early post transplantation reduce risk of acute GVHD and improves survival
artículo científico publicado en 2013
Histone Deacetylase 11 (HDAC11) Is a Regulatory Checkpoint of T-Cell Function: Implications for T-Cell Adoptive Immunotherapy
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scholarly article
Homeostatic expansion occurs independently of costimulatory signals
artículo científico publicado en 2001
Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions
scientific article published on 01 November 2000
Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells
artículo científico publicado en 2006
Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
scientific article published on 12 September 2013
How ibrutinib, a B-cell malignancy drug, became an FDA-approved second-line therapy for steroid-resistant chronic GVHD
artículo científico publicado en 2018
Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice
artículo científico publicado en 2018
Human CD34(+) bone marrow cells regulate stromal production of interleukin-6 and granulocyte colony-stimulating factor and increase the colony-stimulating activity of stroma
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artículo científico publicado el 15 de mayo de 1998
Human Effectors of Acute and Chronic GVHD Overexpress CD83 and Predict Mortality
artículo científico publicado en 2023
Human T regulatory cell therapy: take a billion or so and call me in the morning
artículo científico publicado en 2009
Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation
artículo científico publicado en 2015
Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity
artículo científico publicado en 2017
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells
artículo científico publicado en 2004
Human surfactant protein a suppresses T cell-dependent inflammation and attenuates the manifestations of idiopathic pneumonia syndrome in mice
artículo científico publicado en 2001
ICOSL+ plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist
artículo científico publicado en 2020
IDO in human gut graft-versus-host disease
artículo científico publicado en 2011
IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy
artículo científico publicado en 2007
IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation.
artículo científico publicado en 2012
IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function
artículo científico publicado en 2003
IL-15 administration following syngeneic bone marrow transplantation prolongs survival of lymphoma bearing mice
artículo científico publicado en 1996
IL-2 + Anti-IL2 Complex in Situ Stimulation of Host Tregs Combined with Absence of Donor B7.1 / B7.2: A Novel Approach to Facilitate Chimerism in RIC MHC-Matched Miha-Mismatched BMT Recipients.
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artículo científico publicado en 2009
IL-2 Stimulated Treg Inhibit in Vitro Expansion of Haploidentical Natural Killer (NK) Cells, Which Is Partially Overcome with An IL-2-Diphtheria Toxin Fusion Protein In Vivo,
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artículo científico publicado en 2011
IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer
artículo científico publicado en 2020
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
artículo científico publicado en 2007
IL-2-based immunotherapy after autologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: a phase I/II trial
artículo científico publicado en 2003
IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation
artículo científico publicado en 2009
IL-22 Is Critical To The Pathogenesis Of Cutaneous Gvhd Mediated By Th17 Cells
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artículo científico publicado en 2013
IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells
artículo científico publicado en 2014
IL-7 signaling imparts polyfunctionality and stemness potential to CD4(+) T cells.
artículo científico publicado en 2016
IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function
artículo científico publicado en 2016
Ibrutinib for chronic graft-versus-host disease after failure of prior therapy
artículo científico publicado en 2017
Ibrutinib treatment ameliorates murine chronic graft-versus-host disease
artículo científico publicado en 2014
Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis
artículo científico publicado en 2018
Identification of transfused blood cells in children with severe combined immunodeficiency syndrome by analysis of multiple cell lineages using restriction fragment length polymorphisms
artículo científico publicado en 1990
Immune Reconstitution (IR) after Allogeneic Hematopoietic Cell Transplantation (alloHCT): Comparing Results in Recipients of Unrelated Umbilical Cord Blood (UCB) to Those with an HLA-Matched Sibling Donor Peripheral Blood (MSD PB)
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artículo científico publicado en 2016
Immune Reconstitution after Umbilical Cord Blood Versus Peripheral Blood Progenitor Cell Transplantation in Adults Following Myeloablative Conditioning
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artículo científico publicado en 2016
Immune regulatory cell infusion for graft-versus-host disease prevention and therapy.
artículo científico publicado en 2018
Immune regulatory cells in umbilical cord blood: T regulatory cells and mesenchymal stromal cells
artículo científico publicado en 2009
Immunobiology of allogeneic hematopoietic stem cell transplantation
artículo científico publicado en 2007
Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis
artículo científico publicado en 2014
Impact of ABO-mismatch on risk of GVHD after umbilical cord blood transplantation
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artículo científico publicado el 18 de febrero de 2013
Impact of Allele-Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation
artículo científico publicado en 2015
Impact of Graft Source on Immune Recovery: Comparions Between Unrelated Umbilical Cord Blood (UCB), HLA Matched Sibling (Sib) Donor and Autologous (Auto) Hematopoietic Stem Cells.
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scholarly article
Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD
article
Improved graft-versus-host disease-free, relapse-free survival associated with bone marrow as the stem cell source in adults
scientific article published on April 2016
Improved survival and leukocyte reconstitution without detrimental effects on engraftment in murine recipients of human recombinant granulocyte colony-stimulating factor after transplantation of T-cell-depleted histoincompatible bone marrow
artículo científico publicado en 1989
In Vitro Generation of NK22 Cells From Hematopoietic Stem Cells
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artículo científico publicado en 2010
In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines
artículo científico publicado en 2017
In Vitro T-Cell Generation From Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination
artículo científico publicado en 2015
In situ identification of allospecific B cells using pentamers
artículo científico publicado en 2008
In utero engraftment of fully H-2-incompatible versus congenic adult bone marrow transferred into nonanemic or anemic murine fetal recipients.
artículo científico publicado en 1993
In utero transfer of adult bone marrow cells into recipients with severe combined immunodeficiency disorder yields lymphoid progeny with T- and B-cell functional capabilities
scientific article published on 01 December 1995
In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement
artículo científico publicado en 2006
In vitro tumor-pulsed or in vivo Flt3 ligand-generated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow-transplanted mice
scientific article published on 01 March 2001
In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations
artículo científico publicado en 2008
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures
artículo científico publicado en 2004
In vivo T-cell receptor ligation facilitates alloengraftment and prevents lethal graft-versus-host disease (GVHD) in mice
artículo científico publicado en 1993
In vivo administration of anti-CD3 monoclonal antibodies or immunotoxins in murine recipients of allogeneic T cell-depleted marrow for the promotion of engraftment
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artículo científico publicado el 1 de septiembre de 1991
In vivo administration of recombinant human granulocyte/macrophage colony-stimulating factor in acute lymphoblastic leukemia patients receiving purged autografts.
artículo científico publicado en 1989
In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice
artículo científico publicado en 1994
In vivo imaging of graft-versus-host-disease in mice
artículo científico publicado en 2004
In vivo inhibition of cytokine responsiveness and graft-versus-host disease mortality by rapamycin leads to a clinical-pathological syndrome discrete from that observed with cyclosporin A
artículo científico publicado en 1996
In vivo or in vitro anti-CD3 epsilon chain monoclonal antibody therapy for the prevention of lethal murine graft-versus-host disease across the major histocompatibility barrier in mice.
artículo científico publicado en 1994
In vivo survival and homeostatic proliferation of natural killer cells.
artículo científico publicado en 2003
Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis
artículo científico publicado en 2009
Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.
artículo científico publicado en 2017
Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans
artículo científico publicado en 2014
Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation.
artículo científico publicado en 2014
Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression
artículo científico publicado en 2016
Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality
scientific journal article
Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa
artículo científico publicado en 2010
Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
artículo científico publicado en 2009
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta
artículo científico publicado en 1999
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes
artículo científico publicado en 2018
Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation
artículo científico publicado en 2000
Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells
artículo científico publicado en 2008
Inflammasome effects in GvHD
artículo científico publicado en 2015
Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders
artículo científico publicado en 2006
Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function.
artículo científico publicado en 2014
Infusion of Ex Vivo Activated Donor Type 2 Innate Lymphoid Cells Inhibit Th1 Activity and Reduces Acute Graft-Versus-Host Disease
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artículo científico publicado en 2014
Infusion of anti-B7.1 (CD80) and anti-B7.2 (CD86) monoclonal antibodies inhibits murine graft-versus-host disease lethality in part via direct effects on CD4+ and CD8+ T cells
artículo científico publicado en 1996
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
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artículo científico publicado el 15 de octubre de 2010
Infusions of interleukin-1 alpha after autologous transplantation for Hodgkin's disease and non-Hodgkin's lymphoma induce effector cells with antilymphoma cytolytic activity
artículo científico publicado en 1994
Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration
artículo científico publicado en 2013
Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity
artículo científico publicado en 2018
Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib
artículo científico publicado en 2004
Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease
artículo científico publicado en 2020
Inhibition of pancreatic islet beta cell function by tumor necrosis factor is blocked by a soluble tumor necrosis factor receptor
scientific article published on 01 February 1993
Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD).
artículo científico publicado en 2007
Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice
scientific article published on 01 August 1999
Intercellular adhesion molecule-I (ICAM-I, CD54) deficiency segregates the unique pathophysiological requirements for generating idiopathic pneumonia syndrome (IPS) versus graft-versus-host disease following allogeneic murine bone marrow transplanta
scientific article published on 01 January 2001
Interleukin 2 immediately after autologous bone marrow transplantation for acute lymphoblastic leukemia--a phase I study
artículo científico publicado en 1993
Interleukin-1 alpha administered after autologous transplantation: a phase I/II clinical trial.
artículo científico publicado en 1994
Interleukin-1 alpha-mediated promotion of long-term alloengraftment and short-term neutrophil expansion does not require the presence of either donor or host T cells
scientific article published on 01 September 1996
Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation
artículo científico publicado en 2002
Interleukin-1 or tumor necrosis factor-alpha antagonists do not inhibit graft-versus-host disease induced across the major histocompatibility barrier in mice
scientific article published on 01 December 1995
Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts
scientific article published on 01 February 1995
Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease
artículo científico publicado en 1998
Interleukin-2 gene transfer into murine neuroblastoma decreases tumorigenicity and enhances systemic immunity causing regression of preestablished retroperitoneal tumors
artículo científico publicado en 1994
Interleukin-2 secretion by transduced and unselected BDL-2 lymphoma results in increased survival in mice with previously established disseminated disease
scientific article published on 01 April 1996
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease
artículo científico publicado en 2012
Interleukin-27 Enforces Regulatory T Cell Functions to Prevent Graft-versus-Host Disease
scientific article published on 12 February 2020
Intestinal Helminth Colonization Regulates Lethal Graft Versus Host Disease and Preserves Graft Versus Tumor in Bone Marrow Transplanted Mice
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artículo científico publicado en 2014
Intestinal Immune Conditioning with Helminths Employs Host T Helper 2 (Th2) Pathway to Induce Mixed Chimerism and Regulate Graft-Versus-Host Disease
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scholarly article
Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.
artículo científico publicado en 2014
Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD.
artículo científico publicado en 2014
Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells
artículo científico publicado en 2017
Invasive Fusarium infections in bone marrow transplant recipients
artículo científico publicado en 1984
Irradiation of singly and doubly transduced murine neuroblastoma cells expressing B7-1 and producing interferon-gamma reduces their capacity to induce systemic immunity
scientific article published on 01 March 1996
Isoform-specific targeting of ROCK proteins in immune cells
artículo científico publicado en 2016
KGF and androgen blockade work in concert to protect against conditioning regimen‐induced thymic epithelial damage and enhance T‐cell reconstitution following murine BMT
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scholarly article
KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT
scientific article published on 01 May 2000
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells
artículo científico publicado en 2007
Keratinocyte growth factor administered before conditioning ameliorates graft-versus-host disease after allogeneic bone marrow transplantation in mice
artículo científico publicado en 1998
Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation
artículo científico publicado en 2008
Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques
artículo científico publicado en 2007
Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury
artículo científico publicado en 2000
Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease
scientific article published on 01 July 2002
Keratinocytes from induced pluripotent stem cells in junctional epidermolysis bullosa
artículo científico publicado en 2012
Kinetics of Chimerism and Unit Predominance After Double Umbilical Cord Blood Transplantation
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scholarly article
Kupffer cell engraftment across the major histocompatibility barrier in mice: bone marrow origin, class II antigen expression, and antigen-presenting capacity.
artículo científico publicado en 1990
L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
artículo científico publicado en 2004
Lack of GVHD across classical, single minor histocompatibiliTy (miH) locus barriers in mice
scientific article published on 01 February 1996
Late Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation
artículo científico publicado en 2015
Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy
artículo científico publicado en 2015
Lethal murine graft-versus-host disease induced by donor gamma/delta expressing T cells with specificity for host nonclassical major histocompatibility complex class Ib antigens
artículo científico publicado en 1996
Leukocyte migration and graft-versus-host disease
artículo científico publicado en 2005
Licensing delineates helper and effector NK cell subsets during viral infection
artículo científico publicado en 2017
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
scientific article published on 01 March 2001
Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo
scientific article published on 11 September 2003
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients
artículo científico publicado en 2003
Limited role of MHC class I chain-related gene A (MICA) typing in assessing graft-versus-host disease risk after fully human leukocyte antigen-matched unrelated donor transplantation
artículo científico publicado en 2009
Lineage relationships of human interleukin-22–producing CD56+ RORγt+ innate lymphoid cells and conventional natural killer cells
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artículo científico publicado el 17 de enero de 2013
Lipid Composition of Whole Brain and Cerebellum in Hurler Syndrome (MPS IH) Mice
article
Long-term follow-up of a phase I/II randomized, placebo-controlled trial of palifermin to prevent graft-versus-host disease (GVHD) after related donor allogeneic hematopoietic cell transplantation (HCT).
artículo científico publicado en 2008
Long-term outcome of Hurler syndrome following bone marrow transplantation
artículo científico publicado en 1993
Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality
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scholarly article
Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease
artículo científico publicado en 2016
Low EGF in myeloablative allotransplantation: association with severe acute GvHD in BMT CTN 0402
artículo científico publicado en 2017
Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation
artículo científico publicado en 2016
Low dose subcutaneous interleukin-2 after autologous transplantation generates sustained in vivo natural killer cell activity
artículo científico publicado el 1 de abril de 1997
Low-Dose Interleukin-2 Therapy Restores Regulatory T Cell Homeostasis in Patients with Chronic Graft-Versus-Host Disease
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artículo científico publicado el 3 de abril de 2013
Low-dose IL-2 selectively activates subsets of CD4+ Tregs and NK cells
artículo científico publicado en 2016
Lower leukemia relapse in pediatric patients with pulmonary cytolytic thrombi following allogeneic transplant
artículo científico publicado en 2010
Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation
artículo científico publicado en 2015
Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone
artículo científico publicado en 2007
MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota
scientific article published on 18 September 2019
Maintenance of CD4 T cell fitness through regulation of Foxo1
artículo científico publicado en 2018
Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation
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scholarly article
Manipulating and visualizing T-cell alloresponses
scientific article published on 01 September 2005
Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity
artículo científico publicado en 2011
Mechanisms Responsible for and Strategies To Overcome Bone Marrow (BM) Rejection in Allosensitized Recipients.
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scholarly article
Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation
artículo científico publicado en 2003
Memory T cells in GVHD and GVL.
artículo científico publicado en 2008
Mesenchymal stromal cells from donors varying widely in age are of equal cellular fitness after in vitro expansion under hypoxic conditions
artículo científico publicado en 2010
Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function
scientific article published on 12 March 2020
Metabolic reprogramming augments potency of human pSTAT3-inhibited iTregs to suppress alloreactivity
artículo científico publicado en 2020
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans
artículo científico publicado en 2020
Mgta-456, a Cell Therapy Utilizing Expansion of CD34+ Hematopoietic Stem Cells (HSC), Improves HLA Matching for Adult Recipients, Promotes Faster Hematopoietic Recovery and Enables Uniform Engraftment with Less Acute Graft-Vs-Host Disease (GVHD)
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scholarly article
MiR-155 Impacts T Cell Migration in Acute Graft-Versus-Host Disease (aGVHD)
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artículo científico publicado en 2015
MiR-17-92 Is Required for the Pathogenicity of T and B Cells in Chronic Gvhd
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artículo científico publicado en 2016
MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function
artículo científico publicado en 2018
MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice
artículo científico publicado en 2018
MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection
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artículo científico publicado el 12 de septiembre de 2012
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
artículo científico publicado en 2006
Minicircle DNA is Superior to Plasmid DNA in Eliciting Antigen-specific CD8+ T-cell Responses
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artículo científico publicado el 21 de mayo de 2013
Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of α-L-iduronidase in mice with mucopolysaccharidosis type I
artículo científico publicado en 2010
Minimal PD-1 expression in mouse and human NK cells under diverse conditions
artículo científico publicado en 2020
Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization
artículo científico publicado en 2017
Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function
artículo científico publicado en 2019
Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10
artículo científico publicado en 2014
Modulation of Immune Checkpoints and Graft-versus-Leukemia in Allogeneic Transplants by Antagonizing Vasoactive Intestinal Peptide Signaling
artículo científico publicado en 2016
Molecular modification of a recombinant anti-CD3epsilon-directed immunotoxin by inducing terminal cysteine bridging enhances anti-GVHD efficacy and reduces organ toxicity in a lethal murine model
artículo científico publicado en 2000
Monocyte Subpopulation Recovery and Outcomes Following Hematopoietic Cell Transplantation
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scholarly article
Monocyte Subpopulation Recovery as Predictors of Hematopoietic Cell Transplantation Outcomes
scientific article published on 06 January 2019
Monomeric annexin A2 is an oxygen-regulated toll-like receptor 2 ligand and adjuvant
artículo científico publicado en 2016
Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC
artículo científico publicado en 2011
Mucocutaneous Engraftment and Type VII Collagen (C7) Replacement after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Recessive Dystrophic Epidermolysis Bullosa (RDEB)
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scholarly article
Multicenter Open-Label Phase 2 Study of Ibrutinib in Chronic Graft Versus Host Disease (cGVHD) after Failure of Corticosteroids
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scholarly article
Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming
artículo científico publicado en 2009
Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses
artículo científico publicado en 2022
Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients
artículo científico publicado en 2018
Murine gamma/delta-expressing T cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens
artículo científico publicado en 1996
Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration of rapamycin but develop an autoimmune-like syndrome
artículo científico publicado en 1993
Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: analysis of graft sources and long-term outcome.
artículo científico publicado en 2009
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation
artículo científico publicado en 2004
NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic
scientific article published on 10 February 2010
NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death
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scholarly article
NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution
artículo científico publicado en 2002
NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade
artículo científico publicado en 2003
Natural history of pulmonary complications in children after bone marrow transplantation
artículo científico publicado en 2005
Natural killer–cell differentiation by myeloid progenitors
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artículo científico publicado el 20 de diciembre de 2010
Negative Impact of KIR-Ligand Mismatch on Transplant-Related Mortality (TRM) in Umbilical Cord Blood Transplant (UCBT) Recipients.
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scholarly article
Negative effect of CTLA-4 on induction of T-cell immunity in vivo to B7-1+, but not B7-2+, murine myelogenous leukemia
artículo científico publicado en 2002
Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity
scientific article published on 27 March 2009
Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset
artículo científico publicado en 2018
New strategies for preventing graft-versus-host disease
artículo científico publicado en 1999
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis
artículo científico publicado en 2014
Nonhuman primate transplant models finally evolve: detailed immunogenetic analysis creates new models and strengthens the old.
artículo científico publicado en 2011
Nonmitogenic anti-CD3F(ab')2 fragments inhibit lethal murine graft-versus-host disease induced across the major histocompatibility barrier
artículo científico publicado en 1993
Notch signaling at later stages of NK cell development enhances KIR expression and functional maturation
artículo científico publicado en 2014
Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice
scientific article published on 04 September 2018
Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation
scientific article published on 01 November 2020
Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.
artículo científico publicado en 2018
Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation
scientific article published on 03 April 2020
Opposing Effects of CD70 Costimulation during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection of Mice
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artículo científico publicado el 20 de abril de 2011
Opposing roles of CD28:B7 and CTLA-4:B7 pathways in regulating in vivo alloresponses in murine recipients of MHC disparate T cells
scientific article published on 01 June 1999
Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning
scientific article published on 01 January 2000
Optimal Xenogeneic Adoptive Transfer of Human NK Cells: Fresh NK Cells and IL-15 Administration Are Superior to Frozen NK Cells and IL-2
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scholarly article
Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials
artículo científico publicado en 2016
Organ-Specific Protection By Bortezomib On The Treatment Of Cutaneous Chronic and Acute GvHD
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scholarly article
Organ-Specific Protection from CD8+ T Cell-Mediated Acute Skin GVHD by Bortezomib Administration Correlates with Decreased IL-6.
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artículo científico publicado en 2010
Osteosarcoma Derived from Cultured Mesenchymal Stem Cells.
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artículo científico publicado en 2006
Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity
artículo científico publicado en 2015
Outcome of CNS and pulmonary enteroviral infections after hematopoietic cell transplantation
artículo científico publicado en 2005
Outcome of dialysis for acute renal failure in pediatric bone marrow transplant patients
artículo científico
Outcome of second bone marrow transplantation following a uniform conditioning regimen as therapy for malignant relapse
artículo científico publicado en 1996
Outcomes and Predictors of Response in Steroid-Refractory Acute Graft-versus-Host Disease
scientific article published on 17 July 2019
Outcomes of Chronic Graft-Versus-Host Disease (cGVHD) Following Matched Sibling Donor (MSD) Versus Umbilical Cord Blood Transplant (UCBT)
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artículo científico publicado en 2019
Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo
artículo científico publicado en 2008
Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin
scientific article published on 01 June 2006
Oxygen is a master regulator of the immunogenicity of primary human glioma cells
artículo científico publicado en 2011
PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment
artículo científico publicado en 2020
PD-1 blockade for relapsed lymphoma post-allogeneic hematopoietic cell transplant: high response rate but frequent GVHD.
artículo científico publicado en 2017
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
artículo científico publicado en 2021
PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells
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artículo científico publicado el 9 de noviembre de 2010
PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
artículo científico publicado en 2022
PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection
artículo científico publicado en 2007
PKC-θ function at the immunological synapse: prospects for therapeutic targeting
artículo científico publicado en 2011
PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice
artículo científico publicado en 2009
Palifermin for oral mucositis after intensive therapy for hematologic cancers
artículo científico publicado en 2004
Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting
artículo científico publicado en 2006
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.
artículo científico publicado en 2018
Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation
artículo científico publicado en 2016
Pathology of the liver in mucopolysaccharidosis: light and electron microscopic assessment before and after bone marrow transplantation
artículo científico publicado el 1 de septiembre de 1992
Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets
artículo científico publicado en 2017
Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa
scientific article published on 06 December 2013
Pediatric acute GVHD: clinical phenotype and response to upfront steroids
scientific article published on 02 September 2019
Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.
artículo científico publicado en 2016
Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT
artículo científico publicado en 2021
Peritransplant palifermin use and lymphocyte recovery after T-cell replete, matched related allogeneic hematopoietic cell transplantation
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artículo científico publicado el 1 de octubre de 2011
Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity
artículo científico publicado en 2020
Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation
artículo científico publicado en 2005
Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates
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artículo científico publicado en 2018
Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice
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artículo científico publicado el 3 de octubre de 2013
Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT).
artículo científico publicado en 2006
Phase I Study of Alemtuzumab for Therapy of Steroid-Refractory Chronic Graft-versus-Host Disease
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artículo científico publicado el 14 de febrero de 2013
Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft
artículo científico publicado en 2015
Phenyl N-Tert-Butylnitrone (PBN) Protects Syngeneic Marrow Transplant Recipients from the Lethal Cytokine Syndrome Occurring after Agonistic CD40 Antibody Administration.
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artículo científico publicado en 2004
Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts
artículo científico publicado en 2015
Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or establishment of mixed chimerism
artículo científico publicado en 2002
Physiologic Control of IDO Competence in Splenic Dendritic Cells
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artículo científico publicado el 3 de agosto de 2011
Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression
artículo científico publicado en 2009
Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production
artículo científico publicado en 2017
Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation
artículo científico publicado en 2003
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
artículo científico publicado en 2007
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation
artículo científico publicado en 2019
Polyfunctional CD4+ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy
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artículo científico publicado el 2 de agosto de 2012
Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells
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artículo científico publicado el 3 de octubre de 2003
Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease
artículo científico publicado en 2014
Pre-transplant risk factors affecting outcome in Hurler syndrome
artículo científico publicado en 2009
Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease
artículo científico publicado en 2016
Preclinical models of acute and chronic graft-versus-host disease: how predictive are they for a successful clinical translation?
scientific article published on 18 March 2016
Predictive factors for chronic graft-versus-host disease after histocompatible sibling donor bone marrow transplantation
artículo científico publicado en 1994
Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients
artículo científico publicado en 2006
Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS)
artículo científico publicado en 2012
Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease
artículo científico publicado en 2018
Pretransplant conditioning with busulfan (Myleran) and cyclophosphamide for nonmalignant diseases. Assessment of engraftment following histocompatible allogeneic bone marrow transplantation
artículo científico publicado en 1985
Pretreatment of murine donor grafts with L-leucyl-L-leucine methyl ester: elimination of graft-versus-host disease without detrimental effects on engraftment
artículo científico publicado en 1990
Prevention of Acute GvHD During MHC Haploidentical BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model.
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artículo científico publicado en 2009
Prevention of Acute GvHD during Haplo-BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model
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artículo científico publicado en 2008
Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression
artículo científico publicado en 2013
Prevention of murine graft-versus-host disease and bone marrow alloengraftment across the major histocompatibility barrier after donor graft preincubation with anti-LFA1 immunotoxin
artículo científico publicado en 1991
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.
artículo científico publicado en 2010
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality
artículo científico publicado en 2016
Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity
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scholarly article
Programming of donor T cells using allogeneic δ-like ligand 4-positive dendritic cells to reduce GVHD in mice.
artículo científico publicado en 2016
Prolonged subcutaneous administration of 852A, a novel systemic toll‐like receptor 7 agonist, to activate innate immune responses in patients with advanced hematologic malignancies
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artículo científico publicado el 20 de junio de 2012
Promising Progression Free and Overall Survival Using a Novel (CY/FLU/TBI) Reduced-Intensity Conditioning (RIC) Regimen for Allogeneic Sibling Stem Cell Transplantation (SCT).
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artículo científico publicado en 2006
Promising progression-free survival for patients low and intermediate grade lymphoid malignancies after nonmyeloablative umbilical cord blood transplantation
artículo científico publicado en 2009
Promotion of murine marrow alloengraftment and hematopoietic recovery across the major histocompatibility barrier by administration of recombinant human interleukin-1 alpha
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artículo científico publicado el 15 de septiembre de 1992
Prospective randomized trial between two doses of granulocyte colony-stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent or refractory solid tumors: a children's cancer group report
artículo científico publicado en 2001
Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation
artículo científico publicado en 2002
Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function
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artículo científico publicado en 2015
Protein kinase C-theta mediates negative feedback on regulatory T cell function
artículo científico publicado en 2010
Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease
artículo científico publicado en 2016
Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
scientific article published on 01 August 2019
Pulmonary Complications Due to Iduronidase Deficiency (Hurler Syndrome) Linked to Active Pro-Inflammatory Status.
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artículo científico publicado en 2004
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease
artículo científico publicado en 2024
ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings
artículo científico publicado en 2016
Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of established graft-versus-host disease induced across the major histocompatibility barrier
scientific article published on 01 April 1991
Radiotherapy in mice with yttrium-90-labeled anti-Ly1 monoclonal antibody: therapy of the T cell lymphoma EL4
artículo científico publicado en 1991
Randomized clinical trial of thalidomide, cyclosporine, and prednisone versus cyclosporine and prednisone as initial therapy for chronic graft-versus-host disease
artículo científico publicado en 2001
Randomized comparison of cyclophosphamide-total body irradiation versus busulfan-cyclophosphamide conditioning in autologous bone marrow transplantation for acute myeloid leukemia
artículo científico publicado en 1995
Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production of Th1 or Th1 cytotoxic cytokines
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artículo científico publicado el 1 de junio de 1998
Rapamycin prolongs survival of murine recipients of fully allogeneic donor grafts when administered during the graft-versus-host disease process
artículo científico publicado en 1993
Rapamycin, a potent inhibitor of T-cell function, prevents graft rejection in murine recipients of allogeneic T-cell-depleted donor marrow
artículo científico publicado en 1994
Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning
artículo científico publicado en 2003
Re-Opening Schools Safely: The Case for Collaboration, Constructive Disruption of Pre-COVID Expectations, and Creative Solutions
scientific article published on 20 May 2020
Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells
artículo científico publicado en 1996
Real-time in vivo imaging of stem cells following transgenesis by transposition
artículo científico publicado en 2005
Recent advances in graft‐versus‐host disease (GVHD) prevention
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artículo científico publicado el 1 de junio de 1997
Receptors and counterreceptors involved in NK-B cell interactions
scientific article published on 01 April 2005
Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells.
artículo científico publicado en 2017
Recipient single nucleotide polymorphisms in Paneth cell antimicrobial peptide genes and acute graft-versus-host disease: analysis of BMT CTN-0201 and -0901 samples
article
Recipient-specific T-cell repertoire reconstitution in the gut following murine hematopoietic cell transplant
artículo científico publicado en 2020
Recombinant granulocyte/macrophage-colony stimulating factor in human and murine bone marrow transplantation
artículo científico publicado en 1988
Reduced intensity compared with high dose conditioning for allotransplantation in acute myeloid leukemia and myelodysplastic syndrome: a comparative clinical analysis
artículo científico publicado en 2007
Reduced-Intensity Conditioning Followed by Related and Unrelated Allografts for Hematologic Malignancies: Expanded Analysis and Long-Term Follow-Up
artículo científico publicado en 2018
Reduced-intensity conditioning followed by related allografts in hematologic malignancies: long-term outcomes most successful in indolent and aggressive non-Hodgkin lymphomas
artículo científico publicado en 2010
Reduction in murine acute GVHD severity by human gingival tissue-derived mesenchymal stem cells via the CD39 pathways
scholarly article by Xuhao Ni et al published 8 January 2019 in Cell Death and Disease
Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis
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artículo científico publicado en 2014
Regulation of acute graft-versus-host disease by microRNA-155.
artículo científico publicado en 2012
Regulation of glutathione redox status in lung and liver by conditioning regimens and keratinocyte growth factor in murine allogeneic bone marrow transplantation
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artículo científico publicado el 27 de octubre de 2001
Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation
artículo científico publicado en 2012
Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration
artículo científico publicado en 2020
Regulatory T cell expressed MyD88 is critical for prolongation of allograft survival
artículo científico publicado en 2016
Regulatory T cells
artículo científico publicado en 2005
Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus
artículo científico publicado en 2012
Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?
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artículo científico publicado el 31 de agosto de 2011
Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy
artículo científico publicado en 2008
Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units
artículo científico publicado en 2009
Relationship of Epidermal Growth Factor to Cyclosporine-Assocated Magnesium Wasting and Clinical Outcomes Post-Allogeneic Hematopoietic Cell Transplantation
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artículo científico publicado en 2014
Relationship of plasma pharmacokinetics of high-dose oral busulfan to the outcome of allogeneic bone marrow transplantation in children with thalassemia
artículo científico publicado en 1997
Removal of Donor CD4+ T Cells Markedly Promotes Graft-Versus-Tumor (GVT) Effects and Inhibits GVHD-Dependent Toxicity Associated with Prolonged Bortezomib Administration after Allogeneic BMT.
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artículo científico publicado en 2006
Renal dysfunction accounts for the dose limiting toxicity of DT390anti- CD3sFv, a potential new recombinant anti-GVHD immunotoxin
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artículo científico publicado el 1 de septiembre de 1997
Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer
artículo científico publicado en 2015
Reply
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation
artículo científico publicado en 2011
Reprint of: B cells in chronic graft-versus-host disease
artículo científico publicado en 2015
Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice
artículo científico publicado en 2010
Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses
scientific article published on 24 September 2020
Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
artículo científico publicado en 2017
Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems
artículo científico publicado en 2002
Restoration of CCL21 Accelerates Lymph Node (LN) and Spleen Regeneration Post-Transplant and Improves Anti-Pathogen and Anti-Tumor Effector Responses
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artículo científico publicado en 2012
Restriction fragment length polymorphisms as markers of engraftment in allogeneic marrow transplantation
scientific article published on 01 December 1985
Resurrecting the recalcitrant T-cell
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artículo científico publicado el 20 de octubre de 2011
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells
artículo científico publicado en 2011
Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene.
artículo científico publicado en 2000
Retroviral-mediated transfer of the iduronate-2-sulfatase gene into lymphocytes for treatment of mild Hunter syndrome (mucopolysaccharidosis type II)
scientific article published on 01 March 1996
Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.
artículo científico publicado en 1993
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
artículo científico publicado en 2020
Risk Factors for Acute and Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation with Umbilical Cord Blood and Matched Sibling Donors
artículo científico publicado en 2015
Risk Factors for Acute and Chronic Gvhd after Allogeneic Hematopoietic Cell Transplantation (allo-HCT): Relative Risks with Umbilical Cord Blood (UCB) and Matched Related Donors (MRD)
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artículo científico publicado en 2014
Risk factors for acute graft-versus-host disease in histocompatible donor bone marrow transplantation
scientific article published on 01 June 1991
Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial
artículo científico publicado en 2013
Robert Truitt tribute
artículo científico publicado en 2009
Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease
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scholarly article
Role of Recipient CD8+ T Cell Exhaustion in the Rejection of Adoptively Transferred Haploidentical NK Cells
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artículo científico publicado en 2016
Role of interleukin-12 in acute graft-versus-host disease(1)
artículo científico publicado en 2001
Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation
artículo científico publicado en 2017
Role of transgene regulation in ex vivo lentiviral correction of artemis deficiency
artículo científico publicado en 2015
Roles of CD28, CTLA4, and Inducible Costimulator in Acute Graft-versus-Host Disease in Mice
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artículo científico publicado el 27 de marzo de 2011
Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease
artículo científico publicado en 2019
ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease.
artículo científico publicado en 2015
STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model
artículo científico publicado en 2009
STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells
artículo científico publicado en 2018
STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets
artículo científico publicado en 2020
Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth
scientific article published on 01 March 2019
Sarcoma derived from cultured mesenchymal stem cells
artículo científico publicado en 2006
Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function
artículo científico publicado en 2012
Second infusion of bone marrow for treatment of graft failure after allogeneic bone marrow transplantation
artículo científico publicado en 1994
Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism
artículo científico publicado en 2014
Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization
artículo científico publicado en 2019
Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells
artículo científico publicado en 2010
Serum miR-29a Is Upregulated in Acute Graft-versus-Host Disease and Activates Dendritic Cells through TLR Binding
artículo científico publicado en 2017
Short-course total-lymphoid irradiation combined with total-body irradiation to facilitate engraftment of T cell-depleted marrow across a major histocompatibility barrier in mice
artículo científico publicado en 1988
Short-term ex vivo activation of splenocytes with anti-CD3 plus IL-2 and infusion post-BMT into mice results in in vivo expansion of effector cells with potent anti-lymphoma activity
artículo científico publicado en 1994
Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation
artículo científico publicado en 2009
Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis
artículo científico publicado en 2020
Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy
artículo científico publicado en 2018
Signatures of immune dysfunction predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia
artículo científico publicado en 2022
Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice
artículo científico publicado en 2008
Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation
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artículo científico publicado en 2010
Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free Graft-versus-Host Disease Prophylaxis for Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation
artículo científico publicado en 2016
Skeletal muscle contractile function and neuromuscular performance in Zmpste24 -/- mice, a murine model of human progeria
artículo científico publicado en 2011
Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies
artículo científico publicado en 2008
Sleeping Beauty-Mediated Transposition in Stem Cells
scholarly article
Sleeping Beauty-mediated correction of Fanconi anemia type C.
artículo científico publicado en 2011
Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease
article
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.
artículo científico publicado en 2018
Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system
artículo científico publicado en 2005
Stem Cell Source Dependent Differences in Reconstituting Peripheral T Follicular Helper Cells Following Hematopoietic Cell Transplantation, Their Association with Chronic Gvhd and Role in Response to Influenza Vaccination
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artículo científico publicado en 2014
Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.
artículo científico publicado en 2011
Stress responses, M2 macrophages, and a distinct microbial signature in fatal intestinal acute graft-versus-host disease
scientific article published on 08 August 2019
Striking Clinical, Molecular and Immunological Outcomes in Non-Human Primate Hematopoietic Stem Cell Transplantation Using a Novel OX40L Blockade Agent, KY1005, Combined with Rapamycin
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scholarly article
Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation
artículo científico publicado en 2011
Su1897 – Intestinal Immune Conditioning with Helminths Employ Host T Helper 2 (TH2) Pathway to Induce Mixed Chimerism and Regulate Colitis Associated with Graft-Versus-Host Disease
scholarly article
Successful Remission Rates and Survival after Lymphodepleting Chemotherapy and Donor Lymphocyte Infusion for Relapsed Hematologic Malignancies Postallogeneic Hematopoietic Cell Transplantation
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artículo científico publicado el 10 de diciembre de 2011
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
artículo científico publicado en 2005
Successful allogeneic cryopreserved marrow transplantation
scientific article published on 01 February 1989
Successful donor cell engraftment in a recipient of bone marrow from a cadaveric donor
artículo científico publicado en 1986
Superior efficacy of tumor cell vaccines grown in physiologic oxygen
artículo científico publicado en 2010
Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer
artículo científico publicado en 2014
Suppression of NK Cell-Mediated Bone Marrow Cell Rejection by CD4+CD25+ Regulatory T Cells: Linkage of Adaptive to Innate Responses.
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artículo científico publicado en 2005
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells
artículo científico publicado en 2006
Suppressor function of umbilical cord blood-derived CD4+CD25+ T-regulatory cells exposed to graft-versus-host disease drugs
artículo científico publicado en 2006
Surfactant protein A decreases lung injury and mortality after murine marrow transplantation
artículo científico publicado en 2002
Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation
artículo científico publicado en 2003
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging
artículo científico publicado en 2006
Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses
artículo científico publicado en 2003
Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients
artículo científico publicado en 2001
Synthetic zinc finger nuclease design and rapid assembly
artículo científico publicado en 2011
Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth
artículo científico publicado en 2012
Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells
artículo científico publicado en 2016
T Stem Cell Memory Dynamics during Acute Graft-Versus-Host Disease
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artículo científico publicado en 2015
T cell depletion for graft-versus-host-disease prophylaxis. A perspective on engraftment in mice and humans
artículo científico
T cell depletion with anti-CD5 immunotoxin in histocompatible bone marrow transplantation. The correlation between residual CD5 negative T cells and subsequent graft-versus-host disease
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artículo científico publicado el 1 de septiembre de 1990
T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction
artículo científico publicado en 2017
T-Cell Transcriptome Analysis Reveals the Mechanisms Controlling Synergy Between Costimulation Blockade and mTOR Inhibition during Graft Versus Host Disease Prevention
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scholarly article
T-cell expression of AhR inhibits the maintenance of pTreg cells in the gastrointestinal tract in acute GVHD.
artículo científico publicado en 2017
T-lymphocyte production of macrophage inflammatory protein-1alpha is critical to the recruitment of CD8(+) T cells to the liver, lung, and spleen during graft-versus-host disease.
artículo científico publicado en 2000
TALEN-based gene correction for epidermolysis bullosa.
artículo científico publicado en 2013
TCR affinity and specificity requirements for human regulatory T-cell function
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artículo científico publicado el 7 de febrero de 2012
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection
artículo científico publicado en 2008
TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination
artículo científico publicado en 2019
Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
artículo científico publicado en 2016
Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies
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scholarly article
Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease
artículo científico publicado en 2019
Targeting PKCtheta Inhibits Alloreactivity and Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia and Anti-Infection Activities.
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artículo científico publicado en 2009
Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease
artículo científico publicado en 2015
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
artículo científico publicado en 2010
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
artículo científico publicado en 2011
Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: ex vivo and in vivo studies in mice
artículo científico publicado en 1999
Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM).
artículo científico publicado en 2004
Targeting of the CNS in MPS-IH Using a Nonviral Transferrin-α-l-iduronidase Fusion Gene Product
Targeting of the CNS in MPS-IH using a nonviral transferrin-alpha-L-iduronidase fusion gene product
artículo científico publicado en 2008
Th17/Th22 Cells Mediate Breakthrough Graft-Versus-Host-Disease
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artículo científico publicado en 2015
The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning
artículo científico publicado en 2002
The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease
artículo científico publicado en 2016
The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.
artículo científico publicado en 2015
The Innate Immune Sensor Sting Promotes Donor CD8+ T Cell Activation and Recipient APC Death Early after Preclinical Allogeneic Hematopoietic Stem Cell Transplantation
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scholarly article
The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques
artículo científico publicado en 2016
The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells.
artículo científico publicado en 2015
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment
artículo científico publicado en 2015
The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer
artículo científico publicado en 2016
The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo
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artículo científico publicado el 22 de junio de 2011
The Unexpected and Differential Effect of Cyclosporin A on CD56Bright and CD56Dim NK Cell Expansion, Phenotype, Function and Development from Progenitor Cells.
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scholarly article
The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo
artículo científico publicado en 2002
The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide
artículo científico publicado en 1997
The effect of T subset depletion on the incidence of lethal graft-versus-host disease in a murine major-histocompatibility-complex-mismatched transplantation system
artículo científico publicado en 1987
The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia
artículo científico publicado en 2007
The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation
artículo científico publicado en 2008
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
scientific article published on 01 May 2002
The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation
scientific article published in Nature Communications
The lymph node stromal laminin alpha 5 shapes alloimmunity
scientific article published on 04 February 2020
The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo
artículo científico publicado en 2011
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.
artículo científico publicado en 2003
The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 T cells
artículo científico publicado en 2018
The puzzling world of murine T regulatory cells.
artículo científico publicado en 2002
The role of B7 costimulation by murine acute myeloid leukemia in the generation and function of a CD8+ T-cell line with potent in vivo graft-versus-leukemia properties.
artículo científico publicado en 1997
The role of T cell subsets in regulating the in vivo efficacy of CTLA4-Ig in preventing graft-versus-host disease in recipients of fully MHC or multiple minor histocompatibility-disparate donor inocula
artículo científico publicado en 1994
The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice
artículo científico publicado en 1994
The tissue expression of cytokines in human acute cutaneous graft-versus-host disease
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artículo científico publicado el 27 de agosto de 1995
The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations
artículo científico publicado en 2007
The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease
Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD
artículo científico publicado en 2014
Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels
artículo científico publicado en 2014
Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner
artículo científico publicado en 2016
Therapy for ongoing graft-versus-host disease induced across the major or minor histocompatibility barrier in mice with anti-CD3F(ab')2-ricin toxin A chain immunotoxin
scientific article published on 01 December 1995
Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD
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artículo científico publicado en 2019
Thrombopoietic cytokines in relation to platelet recovery after bone marrow transplantation
artículo científico publicado en 2000
Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors
artículo científico publicado en 2003
Thymic Epithelial Cell Support of Thymopoiesis Does Not Require
artículo científico publicado en 2018
Thymic Shielding (TS) in Recipients of Total Body Irradiation (TBI) and Alternative Donor Hematopoietic Stem Cell Transplant (AD-HSCT): Reduced Risk of Opportunistic Infection in Patients with Fanconi Anemia (FA).
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artículo científico publicado en 2006
Thymic T-cell development in allogeneic stem cell transplantation
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artículo científico publicado el 22 de marzo de 2011
Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor
artículo científico publicado en 2008
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
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artículo científico publicado el 8 de febrero de 2012
Tim-3, a Novel Immune Receptor, Is Constitutively Expressed on Human Natural Killer Cells and Functions as An Activating Coreceptor
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artículo científico publicado en 2010
Tissue mast cell counts may be associated with decreased severity of gastrointestinal acute GVHD and nonrelapse mortality
scientific article published on 01 May 2020
Tolerance induction by third-party "off-the-shelf" CD4+CD25+ Treg cells
artículo científico publicado en 2006
Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell
artículo científico publicado en 2002
Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells
artículo científico publicado en 2010
Toxicity and efficacy of anti-T-cell ricin toxin A chain immunotoxins in a murine model of established graft-versus-host disease induced across the major histocompatibility barrier
artículo científico publicado en 1991
Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity
artículo científico publicado en 2006
Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention
artículo científico publicado en 2015
Transfection of the mouse ICAM-1 gene into murine neuroblastoma enhances susceptibility to lysis, reduces in vivo tumorigenicity and decreases ICAM-2-dependent killing
artículo científico publicado en 1994
Transgene expression and silencing in a tick cell line: A model system for functional tick genomics
artículo científico publicado en 2008
Transgenesis of Multipotent Adult Progenitor Cells (MAPC) with Sleeping Beauty Transposons to Determine MAPC Homing and Persistence in Real-Time In Vivo.
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artículo científico publicado en 2004
Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo
artículo científico publicado en 1995
Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice
artículo científico publicado en 2008
Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells.
artículo científico publicado en 2013
Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy
artículo científico publicado en 2004
Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial
artículo científico publicado en 2008
Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival
artículo científico publicado en 2002
Treatment of Corticosteroid-Refractory Graft-Versus-Host Disease with Ruxolitinib in 95 Patients
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artículo científico publicado en 2015
Treatment of chronic graft-versus-host disease with bortezomib
artículo científico publicado en 2014
Treatment of moderate and severe acute GVHD after allogeneic bone marrow transplantation
scientific article published on 01 August 1994
Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome
artículo científico publicado en 1990
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
artículo científico publicado en 2016
Trispecific Killer Engagers (TriKEs) that contain IL-15 to make NK cells antigen specific and to sustain their persistence and expansion
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artículo científico publicado en 2015
Tumor growth control with IDO-silencing Salmonella--reply
artículo científico publicado en 2013
Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects
artículo científico publicado en 2004
Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors
artículo científico publicado en 2005
Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease
artículo científico publicado en 2017
Umbilical Cord Blood T Cells Express the Natural Cytotoxicity Receptors, NKp30, NKp44 and NKp46 after IL-15 Stimulation, but Only NKp30 Is Functional.
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artículo científico publicado en 2007
Umbilical cord blood T cells express multiple natural cytotoxicity receptors after IL-15 stimulation, but only NKp30 is functional
artículo científico publicado en 2008
Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells
artículo científico publicado en 2008
Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease
artículo científico publicado en 2007
Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect
artículo científico publicado en 2015
Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation
artículo científico publicado en 2015
Understanding chronic GVHD from different angles
artículo científico publicado en 2012
Unrelated donor bone marrow transplantation for children and adolescents with aplastic anaemia or myelodysplasia
artículo científico publicado en 1997
Unrelated donor bone marrow transplantation for children with acute leukemia
scientific article published on 01 February 1997
Unrelated donor bone marrow transplantation for correction of lethal congenital immunodeficiencies
artículo científico publicado en 1992
Unrelated donor bone marrow transplantation for hematological malignancies-current status
artículo científico publicado en 1996
Unrelated donor bone marrow transplantation therapy for chronic myelogenous leukemia
scientific article published on 01 September 1987
Unrelated donor bone marrow transplantation: influence of HLA A and B incompatibility on outcome
artículo científico publicado en 1995
VIP-Receptor Antagonist Enhanced Antileukemic Activity In Mice
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artículo científico publicado en 2013
VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways
scientific article published on 15 October 2020
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
artículo científico publicado en 2020
Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4(+)IL17(+) response
artículo científico publicado en 2014
Validation of Minnesota Acute GVHD Risk Score and Identification of New Factors Associated with Initial Response to Steroids: Not All GVHD Is Created Equal
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artículo científico publicado en 2018
Validation of Minnesota acute graft-versus-host disease Risk Score
artículo científico publicado en 2020
Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy
artículo científico publicado en 2019
Vstm3 is a member of the CD28 family and an important modulator of T-cell function
scientific journal article
What is the Optimal Design-Build-Test Cycle for Clinically Relevant Synthetic CAR T Cell Therapies?
scientific article published on 01 September 2020
Zebrafish stromal cells have endothelial properties and support hematopoietic cells
artículo científico publicado en 2011
Zinc fingers hit off target
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artículo científico publicado el 11 de octubre de 2011
iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy
artículo científico publicado en 2020
mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia
scholarly article
miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg).
artículo científico publicado en 2018
miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency
artículo científico publicado en 2016
miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1
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artículo científico publicado el 25 de febrero de 2011
p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
scientific article published on 01 March 2000
sdf1 Expression reveals a source of perivascular-derived mesenchymal stem cells in zebrafish
artículo científico publicado en 2014