Lista de obras -

A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells

artículo científico publicado en 2019

Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma.

artículo científico publicado en 2017

An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis.

artículo científico publicado en 2010

Association of blood monocyte and lymphocyte count and disease-free interval in dogs with osteosarcoma

scientific article published on 14 September 2010

Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma

scientific article published on 23 August 2019

Autophagy and cancer therapy

artículo científico publicado en 2014

Bacterial Killing Activity of Polymorphonuclear Myeloid-Derived Suppressor Cells Isolated From Tumor-Bearing Dogs

artículo científico publicado en 2019

Biological and molecular characterization of a canine hemangiosarcoma-derived cell line.

artículo científico publicado en 2005

Bisphosphonate conjugation for bone specific drug targeting.

artículo científico publicado en 2018

Canine Cancer: Strategies in Experimental Therapeutics

scientific article published on 15 November 2019

Canine Cutaneous Plasmacytosis: 21 Cases (2005-2015).

artículo científico publicado en 2017

Canine sarcomas as a surrogate for the human disease.

artículo científico publicado en 2018

Carcinoma of the apocrine glands of the anal sac in dogs: 113 cases (1985-1995).

artículo científico publicado en 2003

Changes in cell shape are correlated with metastatic potential in murine and human osteosarcomas.

artículo científico publicado en 2016

Characterization of a low expression haplotype in canine glutathione S-transferase (GSTT1) and its prevalence in golden retrievers.

artículo científico publicado en 2017

Click Conjugation of Cloaked Peptide Ligands to Microbubbles

artículo científico publicado en 2018

Clinical and Immunomodulatory Effects of Toceranib Combined with Low‐Dose Cyclophosphamide in Dogs with Cancer ⬇️

artículo científico publicado el 4 de febrero de 2012

Clinical outcome of partial cystectomy for transitional cell carcinoma of the canine bladder

artículo científico publicado en 2017

Clinical, Pathological, and Ethical Considerations for the Conduct of Clinical Trials in Dogs with Naturally Occurring Cancer: A Comparative Approach to Accelerate Translational Drug Development

scientific article published on 01 December 2018

Combination chemotherapy with L-asparaginase, lomustine, and prednisone for relapsed or refractory canine lymphoma

scientific article published on 01 January 2007

Combination chemotherapy with continuous L-asparaginase, lomustine, and prednisone for relapsed canine lymphoma.

artículo científico publicado en 2009

Comparative analysis of survivin expression in untreated and relapsed canine lymphoma.

artículo científico publicado en 2008

Comparative oncology approach to drug repurposing in osteosarcoma.

artículo científico publicado en 2018

Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere

artículo científico publicado en 2015

Comparison of carboplatin and doxorubicin-based chemotherapy protocols in 470 dogs after amputation for treatment of appendicular osteosarcoma

artículo científico publicado en 2014

Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos)

artículo científico publicado en 2009

Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs

artículo científico publicado en 2020

Correlation of nodal mast cells with clinical outcome in dogs with mast cell tumour and a proposed classification system for the evaluation of node metastasis.

artículo científico publicado en 2014

Cyclooxygenase-2 expression in equine tumors

scientific article published on 01 November 2008

Development of a limited-sampling model for prediction of doxorubicin exposure in dogs.

artículo científico publicado en 2012

Development of an in vitro model of acquired resistance to toceranib phosphate (Palladia®) in canine mast cell tumor.

artículo científico publicado en 2014

Diagnostic accuracy of pre-treatment biopsy for grading soft tissue sarcomas in dogs.

artículo científico publicado en 2012

Disease distribution in canine patients with acanthocytosis: 123 cases.

artículo científico publicado en 2013

Dose-escalating vinblastine for the treatment of canine mast cell tumour.

artículo científico publicado en 2008

Doxorubicin and cyclophosphamide for the treatment of canine lymphoma: a randomized, placebo-controlled study.

artículo científico publicado en 2010

Drug dose and drug choice: Optimizing medical therapy for veterinary cancer

scientific article published on 05 September 2019

Elevated serum thymidine kinase activity in canine splenic hemangiosarcoma*.

artículo científico publicado en 2011

Epidermal growth factor enhances the malignant phenotype in canine mammary carcinoma cell lines.

artículo científico publicado en 2010

Epithelial Cell Adhesion Molecule Expression in Canine Tumours

artículo científico publicado en 2016

Evaluation of a 15-week CHOP protocol for the treatment of canine multicentric lymphoma.

artículo científico publicado en 2012

Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma

scientific article published on 14 February 2007

Evaluation of prognostic factors associated with outcome in dogs with multiple cutaneous mast cell tumors treated with surgery with and without adjuvant treatment: 54 cases (1998-2004).

artículo científico publicado en 2006

Expression and function of survivin in canine osteosarcoma.

artículo científico publicado en 2011

Expression of Phosphorylated KIT in Canine Mast Cell Tumor.

artículo científico

GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma.

artículo científico publicado en 2014

Genomic instability and telomere fusion of canine osteosarcoma cells.

artículo científico publicado en 2012

Geographical differences in survival of dogs with non-Hodgkin lymphoma treated with a CHOP based chemotherapy protocol

artículo científico publicado en 2017

Glucose transporter 1 expression in canine osteosarcoma.

artículo científico publicado en 2008

Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo.

artículo científico publicado en 2011

HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

artículo científico publicado en 2013

Human granulocyte-macrophage colony-stimulating factor DNA cationic-lipid complexed autologous tumour cell vaccination in the treatment of canine B-cell multicentric lymphoma

scientific article published on 01 December 2007

IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma

artículo científico publicado en 2004

Imatinib mesylate inhibits platelet-derived growth factor activity and increases chemosensitivity in feline vaccine-associated sarcoma.

artículo científico publicado en 2004

Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study

artículo científico publicado en 2015

Impact of telomerase status on canine osteosarcoma patients.

artículo científico publicado en 2008

In vitro antineoplastic effects of auranofin in canine lymphoma cells.

artículo científico publicado en 2018

In vitro effects of PI3K/mTOR inhibition in canine hemangiosarcoma

artículo científico publicado en 2018

Increased monocyte chemotactic protein-1 concentration and monocyte count independently associate with a poor prognosis in dogs with lymphoma

artículo científico publicado en 2010

Induction of VEGF by tepoxalin does not lead to increased tumour growth in a canine osteosarcoma xenograft.

artículo científico publicado en 2010

Interactions between radiation therapy and immunotherapy: the best of two worlds?

scientific article published on 01 December 2006

Interleukin-11 receptor alpha is expressed on canine osteosarcoma.

artículo científico publicado en 2010

Intralesional lipid-complexed cytokine/superantigen immunogene therapy for spontaneous canine tumors

artículo científico publicado en 2003

Intrinsic Radiosensitivity and Cellular Characterization of 27 Canine Cancer Cell Lines

artículo científico publicado en 2016

Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling

artículo científico publicado en 2019

Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature

artículo científico publicado en 2009

Low-dose cyclophosphamide selectively decreases regulatory T cells and inhibits angiogenesis in dogs with soft tissue sarcoma.

artículo científico publicado en 2011

Lung tumor development and spontaneous regression in lambs coinfected with Jaagsiekte sheep retrovirus and ovine lentivirus.

artículo científico publicado en 2010

Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma

artículo científico publicado en 2015

Malignant mesenchymoma with widespread metastasis including bone marrow involvement in a dog.

artículo científico publicado en 2014

Multicenter prospective trial of hypofractionated radiation treatment, toceranib, and prednisone for measurable canine mast cell tumors.

artículo científico publicado en 2011

NOD/SCID mouse model of canine T-cell lymphoma with humoral hypercalcaemia of malignancy: cytokine gene expression profiling and in vivo bioluminescent imaging

artículo científico publicado en 2008

Novel Treatments for Lymphoma

scientific article published on 29 May 2019

Novel acyclic nucleotide analogues GS-343074 and GS-424044 demonstrate antiproliferative and pro-apoptotic activity in canine neoplastic cell lines.

artículo científico

Optofluidic intracavity spectroscopy of canine hemangiosarcoma.

artículo científico publicado en 2010

Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases

artículo científico publicado en 2006

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

artículo científico publicado en 2016

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

artículo científico publicado en 2014

Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer.

artículo científico publicado en 2010

Phase II clinical evaluation of lomustine chemotherapy for feline vaccine‐associated sarcoma ⬇️

artículo científico publicado el 17 de octubre de 2011

Phase II evaluation of VDC-1101 in canine cutaneous T-cell lymphoma

artículo científico publicado en 2014

Phosphorylated KIT as a predictor of outcome in canine mast cell tumours treated with toceranib phosphate or vinblastine

artículo científico publicado en 2019

Pilot study utilizing Fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography for glycolytic phenotyping of canine mast cell tumors

artículo científico publicado en 2018

Plasma synthesis of carbon magnetic nanoparticles and immobilization of doxorubicin for targeted drug delivery.

artículo científico publicado en 2004

Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer.

artículo científico publicado en 2009

Postsurgical Outcome in Cats with Exocrine Pancreatic Carcinoma: Nine Cases (2007-2016)

scientific article published on 24 July 2018

Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma

artículo científico publicado en 2012

Preclinical study of dolastatin-10 in dogs with spontaneous neoplasia

artículo científico publicado en 2001

Prednisone and vinblastine chemotherapy for canine mast cell tumor--41 cases (1992-1997)

artículo científico publicado en 1999

Preliminary evidence for biologic activity of toceranib phosphate (Palladia(®)) in solid tumours.

artículo científico publicado en 2011

Prognostic and predictive significance of KIT protein expression and c-kit gene mutation in canine cutaneous mast cell tumours: A consensus of the Oncology-Pathology Working Group

scientific article published on 09 July 2019

Prognostic significance of circulating microRNA-214 and -126 in dogs with appendicular osteosarcoma receiving amputation and chemotherapy

scientific article published on 25 January 2019

Prognostic value of fluorine flourodeoxyglucose positron emission tomography/computed tomography in dogs with appendicular osteosarcoma

artículo científico publicado en 2019

Prospective evaluation of flow cytometric characteristics, histopathologic diagnosis and clinical outcome in dogs with naïve B-cell lymphoma treated with a 19-week CHOP protocol

scientific article published on 04 November 2019

Prospective evaluation of toceranib phosphate in metastatic canine osteosarcoma.

artículo científico publicado en 2017

Proteus mirabilis inhibits cancer growth and pulmonary metastasis in a mouse breast cancer model.

artículo científico publicado en 2017

Pulse-Administered Toceranib Phosphate Plus Lomustine for Treatment of Unresectable Mast Cell Tumors in Dogs

artículo científico publicado en 2015

RT-PCR-based tyrosine kinase display profiling of canine melanoma: IGF-1 receptor as a potential therapeutic target.

artículo científico publicado en 2010

Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses.

artículo científico publicado en 2017

Recommended Guidelines for the Conduct and Evaluation of Prognostic Studies in Veterinary Oncology

artículo científico publicado en 2010

Relative biological effectiveness in canine osteosarcoma cells irradiated with accelerated charged particles

scientific article published on 30 June 2016

Response evaluation criteria for solid tumours in dogs (v1.0): a Veterinary Cooperative Oncology Group (VCOG) consensus document.

artículo científico publicado en 2013

Retrospective analysis for treatment of naïve canine multicentric lymphoma with a 15-week, maintenance-free CHOP protocol.

artículo científico publicado en 2015

Retrospective evaluation of doxorubicin-piroxicam combination for the treatment of transitional cell carcinoma in dogs

scientific article published on 03 January 2013

Serum 25-hydroxyvitamin D concentrations in dogs - correlation with health and cancer risk

artículo científico publicado en 2014

Serum vascular endothelial growth factor concentrations and postsurgical outcome in dogs with osteosarcoma.

artículo científico publicado en 2008

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

artículo científico publicado en 2018

Substitution of mitoxantrone for doxorubicin in a multidrug chemotherapeutic protocol for first-line treatment of dogs with multicentric intermediate- to large-cell lymphoma

artículo científico publicado en 2019

Survivin inhibition via EZN-3042 in canine lymphoma and osteosarcoma.

artículo científico publicado en 2014

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

artículo científico publicado en 2010

The Flint Animal Cancer Center (FACC) Canine Tumour Cell Line Panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.

artículo científico publicado en 2016

The immunosignature of canine lymphoma: characterization and diagnostic application

artículo científico publicado en 2014

Tyrosine kinase inhibitor special issue

artículo científico publicado en 2012

Veterinary oncology clinical trials: design and implementation.

artículo científico

Vinorelbine rescue therapy for dogs with primary urinary bladder carcinoma.

artículo científico publicado en 2013

What is your diagnosis? A soft-tissue mass in the thoracic cavity between the heart and the right crus of the diaphragm

artículo científico publicado en 2000

c-Kit Mutation and Localization Status as Response Predictors in Mast Cell Tumors in Dogs Treated with Prednisone and Toceranib or Vinblastine.

artículo científico publicado en 2017

c-Met tyrosine kinase receptor expression and function in human and canine osteosarcoma cells

artículo científico publicado el 1 de enero de 2003

Lista de obras de

A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells

Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma.

An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis.

Association of blood monocyte and lymphocyte count and disease-free interval in dogs with osteosarcoma

Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma

Autophagy and cancer therapy

Bacterial Killing Activity of Polymorphonuclear Myeloid-Derived Suppressor Cells Isolated From Tumor-Bearing Dogs

Biological and molecular characterization of a canine hemangiosarcoma-derived cell line.

Bisphosphonate conjugation for bone specific drug targeting.

Canine Cancer: Strategies in Experimental Therapeutics

Canine Cutaneous Plasmacytosis: 21 Cases (2005-2015).

Canine sarcomas as a surrogate for the human disease.

Carcinoma of the apocrine glands of the anal sac in dogs: 113 cases (1985-1995).

Changes in cell shape are correlated with metastatic potential in murine and human osteosarcomas.

Characterization of a low expression haplotype in canine glutathione S-transferase (GSTT1) and its prevalence in golden retrievers.

Click Conjugation of Cloaked Peptide Ligands to Microbubbles

Clinical and Immunomodulatory Effects of Toceranib Combined with Low‐Dose Cyclophosphamide in Dogs with Cancer ⬇️

Clinical outcome of partial cystectomy for transitional cell carcinoma of the canine bladder

Clinical, Pathological, and Ethical Considerations for the Conduct of Clinical Trials in Dogs with Naturally Occurring Cancer: A Comparative Approach to Accelerate Translational Drug Development

Combination chemotherapy with L-asparaginase, lomustine, and prednisone for relapsed or refractory canine lymphoma

Combination chemotherapy with continuous L-asparaginase, lomustine, and prednisone for relapsed canine lymphoma.

Comparative analysis of survivin expression in untreated and relapsed canine lymphoma.

Comparative oncology approach to drug repurposing in osteosarcoma.

Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere

Comparison of carboplatin and doxorubicin-based chemotherapy protocols in 470 dogs after amputation for treatment of appendicular osteosarcoma

Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos)

Concurrent use of rabacfosadine and L-asparaginase for relapsed or refractory multicentric lymphoma in dogs

Correlation of nodal mast cells with clinical outcome in dogs with mast cell tumour and a proposed classification system for the evaluation of node metastasis.

Cyclooxygenase-2 expression in equine tumors

Development of a limited-sampling model for prediction of doxorubicin exposure in dogs.

Development of an in vitro model of acquired resistance to toceranib phosphate (Palladia®) in canine mast cell tumor.

Diagnostic accuracy of pre-treatment biopsy for grading soft tissue sarcomas in dogs.

Disease distribution in canine patients with acanthocytosis: 123 cases.

Dose-escalating vinblastine for the treatment of canine mast cell tumour.

Doxorubicin and cyclophosphamide for the treatment of canine lymphoma: a randomized, placebo-controlled study.

Drug dose and drug choice: Optimizing medical therapy for veterinary cancer

Elevated serum thymidine kinase activity in canine splenic hemangiosarcoma*.

Epidermal growth factor enhances the malignant phenotype in canine mammary carcinoma cell lines.

Epithelial Cell Adhesion Molecule Expression in Canine Tumours

Evaluation of a 15-week CHOP protocol for the treatment of canine multicentric lymphoma.

Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma

Evaluation of prognostic factors associated with outcome in dogs with multiple cutaneous mast cell tumors treated with surgery with and without adjuvant treatment: 54 cases (1998-2004).

Expression and function of survivin in canine osteosarcoma.

Expression of Phosphorylated KIT in Canine Mast Cell Tumor.

GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma.

Genomic instability and telomere fusion of canine osteosarcoma cells.

Geographical differences in survival of dogs with non-Hodgkin lymphoma treated with a CHOP based chemotherapy protocol

Glucose transporter 1 expression in canine osteosarcoma.

Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo.

HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

Human granulocyte-macrophage colony-stimulating factor DNA cationic-lipid complexed autologous tumour cell vaccination in the treatment of canine B-cell multicentric lymphoma

IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma

Imatinib mesylate inhibits platelet-derived growth factor activity and increases chemosensitivity in feline vaccine-associated sarcoma.

Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study

Impact of telomerase status on canine osteosarcoma patients.

In vitro antineoplastic effects of auranofin in canine lymphoma cells.

In vitro effects of PI3K/mTOR inhibition in canine hemangiosarcoma

Increased monocyte chemotactic protein-1 concentration and monocyte count independently associate with a poor prognosis in dogs with lymphoma

Induction of VEGF by tepoxalin does not lead to increased tumour growth in a canine osteosarcoma xenograft.

Interactions between radiation therapy and immunotherapy: the best of two worlds?

Interleukin-11 receptor alpha is expressed on canine osteosarcoma.

Intralesional lipid-complexed cytokine/superantigen immunogene therapy for spontaneous canine tumors

Intrinsic Radiosensitivity and Cellular Characterization of 27 Canine Cancer Cell Lines

Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling

Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature

Low-dose cyclophosphamide selectively decreases regulatory T cells and inhibits angiogenesis in dogs with soft tissue sarcoma.

Lung tumor development and spontaneous regression in lambs coinfected with Jaagsiekte sheep retrovirus and ovine lentivirus.

Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma

Malignant mesenchymoma with widespread metastasis including bone marrow involvement in a dog.

Multicenter prospective trial of hypofractionated radiation treatment, toceranib, and prednisone for measurable canine mast cell tumors.

NOD/SCID mouse model of canine T-cell lymphoma with humoral hypercalcaemia of malignancy: cytokine gene expression profiling and in vivo bioluminescent imaging

Novel Treatments for Lymphoma

Novel acyclic nucleotide analogues GS-343074 and GS-424044 demonstrate antiproliferative and pro-apoptotic activity in canine neoplastic cell lines.

Optofluidic intracavity spectroscopy of canine hemangiosarcoma.

Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer.

Phase II clinical evaluation of lomustine chemotherapy for feline vaccine‐associated sarcoma ⬇️