Lista de obras - Martijn C Nawijn - Dominio Público Uruguay

A cellular census of human lungs identifies novel cell states in health and in asthma

artículo científico publicado en 2019

A specific DAMP profile identifies susceptibility to smoke-induced airway inflammation.

artículo científico publicado en 2013

Airway epithelial barrier function regulates the pathogenesis of allergic asthma.

artículo científico

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2024

An integrated cell atlas of the lung in health and disease

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis

artículo científico

Basophil activation test in mastocytosis patients with and without wasp venom allergy

artículo científico publicado en 2014

Basophil activation test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy on immunotherapy

artículo científico publicado en 2014

Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?

artículo científico publicado en 2020

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

artículo científico publicado en 2018

Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation

artículo científico publicado en 2011

Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

scientific article published in Scientific Reports

Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release

artículo científico publicado en 2015

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

artículo científico publicado en 2015

Comparison of genome-wide gene expression profiling by RNA Sequencing <i>versus</i> microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

artículo científico

Computational analysis of multimorbidity between asthma, eczema and rhinitis

artículo científico publicado en 2017

Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy

artículo científico publicado en 2012

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study

artículo científico publicado en 2015

Cryopreservation does not alter the frequency of regulatory T cells in peripheral blood mononuclear cells

artículo científico publicado en 2009

Cytotoxic T lymphocyte antigen 4-immunoglobulin G is a potent adjuvant for experimental allergen immunotherapy

artículo científico publicado en 2013

DAMPs activating innate and adaptive immune responses in COPD.

artículo científico

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

artículo científico publicado en 2018

Decoding asthma: translating genetic variation in IL33 and IL1RL1 into disease pathophysiology.

artículo científico publicado en 2013

E-cadherin: gatekeeper of airway mucosa and allergic sensitization ⬇️

artículo científico publicado el 12 de abril de 2011

Flow cytometric analysis of cytokine expression in short-term allergen-stimulated T cells mirrors the phenotype of proliferating T cells in long-term cultures

artículo científico publicado en 2011

For better or for worse: the role of Pim oncogenes in tumorigenesis ⬇️

artículo científico publicado el 9 de diciembre de 2010

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

artículo científico publicado en 2009

GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma.

artículo científico publicado en 2009

Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma

artículo científico publicado en 2018

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice

artículo científico publicado en 2017

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice.

artículo científico publicado en 2015

House dust mite-induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production.

artículo científico publicado en 2013

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations

artículo científico publicado en 2016

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients.

artículo científico publicado en 2015

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

artículo científico publicado en 2015

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

artículo científico publicado en 2016

Iron administration reduces airway hyperreactivity and eosinophilia in a mouse model of allergic asthma

scientific article published on 01 October 2011

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

artículo científico publicado en 2017

Methods for Experimental Allergen Immunotherapy: Subcutaneous and Sublingual Desensitization in Mouse Models of Allergic Asthma

artículo científico publicado en 2021

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

artículo científico publicado en 2014

Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice

artículo científico publicado en 2013

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015.

artículo científico publicado en 2016

Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure

artículo científico publicado en 2015

Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation.

artículo científico publicado en 2014

Pim3 negatively regulates glucose-stimulated insulin secretion ⬇️

artículo científico publicado el 1 de septiembre de 2010

Predictive value of serum sST2 in preschool wheezers for development of asthma with high FeNO.

artículo científico publicado en 2017

Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.

artículo científico publicado en 2014

Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

artículo científico publicado en 2016

Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription

artículo científico publicado en 2015

Protocadherin-1: Epithelial barrier dysfunction in asthma and eczema

artículo científico publicado en 2014

Recent advances in the epigenetics and genomics of asthma.

artículo científico publicado en 2011

Serum periostin does not reflect type 2-driven inflammation in COPD.

artículo científico publicado en 2018

Shared DNA methylation signatures in childhood allergy: the MeDALL study

artículo científico publicado en 2020

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

artículo científico publicado en 2020

Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.

artículo científico publicado en 2017

Subcutaneous immunotherapy suppresses Th2 inflammation and induces neutralizing antibodies, but sublingual immunotherapy suppresses airway hyperresponsiveness in grass pollen mouse models for allergic asthma

artículo científico publicado en 2018

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model

artículo científico publicado en 2018

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice.

artículo científico publicado en 2010

Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.

artículo científico publicado en 2016

Susceptibility to chronic mucus hypersecretion, a genome wide association study

artículo científico publicado en 2014

TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice.

artículo científico publicado en 2013

The Human Cell Atlas

artículo científico publicado en 2017

The Human Cell Atlas

The Human Cell Atlas White Paper ⬇️

artículo científico publicado en 2018

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

scientific article published on 01 July 2019

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma

artículo científico publicado en 2016

The discovAIR project: a roadmap towards the Human Lung Cell Atlas

artículo científico

The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders.

artículo científico

The single-cell eQTLGen consortium

artículo científico publicado en 2020

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar

artículo científico

Lista de obras de Martijn C Nawijn

A cellular census of human lungs identifies novel cell states in health and in asthma

A specific DAMP profile identifies susceptibility to smoke-induced airway inflammation.

Airway epithelial barrier function regulates the pathogenesis of allergic asthma.

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

An integrated cell atlas of the lung in health and disease

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis

Basophil activation test in mastocytosis patients with and without wasp venom allergy

Basophil activation test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy on immunotherapy

Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation

Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

Comparison of genome-wide gene expression profiling by RNA Sequencing <i>versus</i> microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

Computational analysis of multimorbidity between asthma, eczema and rhinitis

Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study

Cryopreservation does not alter the frequency of regulatory T cells in peripheral blood mononuclear cells

Cytotoxic T lymphocyte antigen 4-immunoglobulin G is a potent adjuvant for experimental allergen immunotherapy

DAMPs activating innate and adaptive immune responses in COPD.

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

Decoding asthma: translating genetic variation in IL33 and IL1RL1 into disease pathophysiology.

E-cadherin: gatekeeper of airway mucosa and allergic sensitization ⬇️

Flow cytometric analysis of cytokine expression in short-term allergen-stimulated T cells mirrors the phenotype of proliferating T cells in long-term cultures

For better or for worse: the role of Pim oncogenes in tumorigenesis ⬇️

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma.

Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice.

House dust mite-induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production.

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients.

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

Iron administration reduces airway hyperreactivity and eosinophilia in a mouse model of allergic asthma

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

Methods for Experimental Allergen Immunotherapy: Subcutaneous and Sublingual Desensitization in Mouse Models of Allergic Asthma

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015.

Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure

Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation.

Pim3 negatively regulates glucose-stimulated insulin secretion ⬇️

Predictive value of serum sST2 in preschool wheezers for development of asthma with high FeNO.

Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.

Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription

Protocadherin-1: Epithelial barrier dysfunction in asthma and eczema

Recent advances in the epigenetics and genomics of asthma.

Serum periostin does not reflect type 2-driven inflammation in COPD.

Shared DNA methylation signatures in childhood allergy: the MeDALL study

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.

Subcutaneous immunotherapy suppresses Th2 inflammation and induces neutralizing antibodies, but sublingual immunotherapy suppresses airway hyperresponsiveness in grass pollen mouse models for allergic asthma

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice.

Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.

Susceptibility to chronic mucus hypersecretion, a genome wide association study

TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice.

The Human Cell Atlas

The Human Cell Atlas

The Human Cell Atlas White Paper ⬇️

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma

The discovAIR project: a roadmap towards the Human Lung Cell Atlas

The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders.

The single-cell eQTLGen consortium

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar