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A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

scientific article published on 07 July 2020

Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets.

artículo científico publicado en 2010

Altered fibrinolysis in autosomal dominant thrombomodulin-associated coagulopathy.

scientific article published on 19 July 2016

An international study on the feasibility of a standardized combined plasma clot turbidity and lysis assay: communication from the SSC of the ISTH.

artículo científico publicado en 2018

Defective α2 antiplasmin cross-linking and thrombus stability in a case of acquired factor XIII deficiency

artículo científico publicado en 2017

Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

scientific article published on 01 March 2020

Emerging roles for factor XII in vivo

artículo científico publicado en 2011

Endothelial cell oxidative stress in diabetes: a key driver of cardiovascular complications?

artículo científico publicado en 2014

Evaluation of and recommendation for the nomenclature of the CPB2 gene product (also known as TAFI and proCPU): communication from the SSC of the ISTH.

artículo científico publicado en 2015

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

artículo científico publicado en 2011

Functional factor XIII-A is exposed on the stimulated platelet surface

artículo científico publicado en 2014

Harmonisation of D-dimer - A call for action

artículo científico publicado en 2015

Human thrombi contain an abundance of active thrombin

artículo científico publicado en 2001

Immobilized transition metal ions stimulate contact activation and drive factor XII‐mediated coagulation ⬇️

artículo científico publicado el 1 de octubre de 2012

Insights into thrombin activatable fibrinolysis inhibitor function and regulation.

artículo científico

Let's cross-link: diverse functions of the promiscuous cellular transglutaminase factor XIII-A

artículo científico publicado en 2019

Localization and identification of thrombin and plasminogen activator activities in model human thrombi by in situ zymography

artículo científico publicado en 2002

Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis

artículo científico publicado en 2010

Novel aspects of platelet factor XIII function

artículo científico publicado en 2016

Plasmin and the thrombin-thrombomodulin complex both contribute to thrombin-activatable fibrinolysis inhibitor activation in whole blood model thrombi.

artículo científico publicado en 2013

Plasminogen activator inhibitor-1 and haemostasis in obesity.

artículo científico publicado en 2001

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

artículo científico publicado en 2015

Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

artículo científico publicado en 2009

Platelet-Mediated Modulation of Fibrinolysis.

artículo científico publicado en 2017

Polyphosphate as a haemostatic modulator

artículo científico publicado en 2016

Polyphosphate binds with high affinity to exosite II of thrombin.

artículo científico publicado en 2009

Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity

artículo científico publicado en 2016

Polyphosphate delays fibrin polymerisation and alters the mechanical properties of the fibrin network ⬇️

artículo científico publicado en 2016

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

artículo científico publicado en 2010

Polyphosphate modulates blood coagulation and fibrinolysis.

artículo científico publicado en 2006

Polyphosphate scores a hat trick in regulating host defense mechanisms ⬇️

artículo científico publicado el 1 de junio de 2012

Single-chain factor XII exhibits activity when complexed to polyphosphate

artículo científico publicado en 2014

The antifibrinolytic function of factor XIII is exclusively expressed through α₂-antiplasmin cross-linking.

artículo científico publicado en 2011

The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro

artículo científico publicado en 2007

Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome).

artículo científico publicado en 2015

Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers: a prospective analysis.

artículo científico publicado en 2013

Thrombus lysis by uPA, scuPA and tPA is regulated by plasma TAFI

artículo científico publicado en 2003

Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation.

artículo científico publicado en 2013

Lista de obras de

A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets.

Altered fibrinolysis in autosomal dominant thrombomodulin-associated coagulopathy.

An international study on the feasibility of a standardized combined plasma clot turbidity and lysis assay: communication from the SSC of the ISTH.

Defective α2 antiplasmin cross-linking and thrombus stability in a case of acquired factor XIII deficiency

Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

Emerging roles for factor XII in vivo

Endothelial cell oxidative stress in diabetes: a key driver of cardiovascular complications?

Evaluation of and recommendation for the nomenclature of the CPB2 gene product (also known as TAFI and proCPU): communication from the SSC of the ISTH.

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

Functional factor XIII-A is exposed on the stimulated platelet surface

Harmonisation of D-dimer - A call for action

Human thrombi contain an abundance of active thrombin

Immobilized transition metal ions stimulate contact activation and drive factor XII‐mediated coagulation ⬇️

Insights into thrombin activatable fibrinolysis inhibitor function and regulation.

Let's cross-link: diverse functions of the promiscuous cellular transglutaminase factor XIII-A

Localization and identification of thrombin and plasminogen activator activities in model human thrombi by in situ zymography

Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis

Novel aspects of platelet factor XIII function

Plasmin and the thrombin-thrombomodulin complex both contribute to thrombin-activatable fibrinolysis inhibitor activation in whole blood model thrombi.

Plasminogen activator inhibitor-1 and haemostasis in obesity.

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

Platelet-Mediated Modulation of Fibrinolysis.

Polyphosphate as a haemostatic modulator

Polyphosphate binds with high affinity to exosite II of thrombin.

Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity

Polyphosphate delays fibrin polymerisation and alters the mechanical properties of the fibrin network ⬇️

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

Polyphosphate modulates blood coagulation and fibrinolysis.

Polyphosphate scores a hat trick in regulating host defense mechanisms ⬇️

Single-chain factor XII exhibits activity when complexed to polyphosphate

The antifibrinolytic function of factor XIII is exclusively expressed through α₂-antiplasmin cross-linking.

The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro

Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome).

Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers: a prospective analysis.

Thrombus lysis by uPA, scuPA and tPA is regulated by plasma TAFI

Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation.