Lista de obras - John J Miles - Dominio Público Uruguay

A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

artículo científico publicado en 2014

A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy

artículo científico publicado en 2015

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

artículo científico publicado en 2007

A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics

artículo científico publicado en 2020

A single autoimmune T cell receptor recognizes more than a million different peptides

artículo científico publicado en 2011

Advances in T-cell epitope engineering

artículo científico publicado en 2013

Allelic polymorphism in the T cell receptor and its impact on immune responses

artículo científico publicado en 2010

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

artículo científico publicado en 2006

An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant

artículo científico publicado en 2014

Anomalies in T Cell Function Are Associated With Individuals at Risk of Mycobacterium abscessus Complex Infection.

artículo científico publicado en 2018

Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection

artículo científico publicado en 2005

Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining

artículo científico publicado en 2011

Antibody response to common human viruses is shaped by genetic factors

artículo científico publicado en 2018

Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs

artículo científico publicado en 2014

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection

artículo científico publicado en 2010

Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination

artículo científico publicado en 2011

Bone marrow transplantation generates T cell-dependent control of myeloma in mice

artículo científico publicado en 2018

CD8(+) T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope

artículo científico publicado en 2013

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

artículo científico publicado en 2014

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

artículo científico publicado en 2012

CTL recognition of a bulged viral peptide involves biased TCR selection

artículo científico publicado en 2005

Coinfection with Human Cytomegalovirus Genetic Variants in Transplant Recipients and Its Impact on Antiviral T Cell Immune Reconstitution

artículo científico publicado en 2016

Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells

artículo científico publicado en 2014

Design, synthesis and evaluation of β-lactam antigenic peptide hybrids; unusual opening of the β-lactam ring in acidic media ⬇️

artículo científico publicado el 7 de octubre de 2010

Differential pulsatile secretagogue control of GH secretion in healthy men ⬇️

artículo científico publicado el 13 de marzo de 2013

Diversity of Rhizoctonia spp. Causing Foliar Blight on Brachiaria in Colombia and Evaluation of Brachiaria Genotypes for Foliar Blight Resistance

scientific article published on 01 June 2013

Endogenous presentation of CD8+ T cell epitopes from Epstein-Barr virus-encoded nuclear antigen 1.

artículo científico publicado en 2004

Engineered T cell receptors and their potential in molecular medicine

artículo científico publicado en 2006

Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells

artículo científico publicado en 2016

Erratum: Tracking the T-cell repertoire after adoptive therapy

artículo científico publicado en 2017

Exploring immunomodulation by endocrine changes in Lady Windermere syndrome

artículo científico publicado en 2019

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

artículo científico publicado en 2010

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

artículo científico publicado en 2009

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

artículo científico publicado en 2018

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.

artículo científico publicado en 2018

HLA peptide length preferences control CD8+ T cell responses

artículo científico publicado en 2013

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

artículo científico publicado en 2010

Helminth Immunomodulation in Autoimmune Disease

artículo científico publicado en 2017

High frequency of herpesvirus-specific clonotypes in the human T cell repertoire can remain stable over decades with minimal turnover

artículo científico publicado en 2012

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance

artículo científico publicado en 2005

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

artículo científico publicado en 2013

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes

scientific article published on 25 March 2019

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

artículo científico publicado en 2016

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

artículo científico publicado en 2016

How the Cobra Got Its Flesh-Eating Venom: Cytotoxicity as a Defensive Innovation and Its Co-Evolution with Hooding, Aposematic Marking, and Spitting

artículo científico publicado en 2017

Human CD141+ Dendritic Cell and CD1c+ Dendritic Cell Undergo Concordant Early Genetic Programming after Activation in Humanized Mice In Vivo

artículo científico publicado en 2017

IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling

artículo científico publicado en 2013

Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors

artículo científico publicado en 2016

Immune drug discovery from venoms.

artículo científico publicado en 2017

Immune parameters to consider when choosing T-cell receptors for therapy

artículo científico publicado en 2013

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

artículo científico publicado en 2012

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

artículo científico publicado en 2008

Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.

artículo científico publicado en 2018

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

artículo científico publicado en 2010

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

artículo científico publicado en 2014

Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipients

artículo científico publicado en 2016

Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) Web-Server.

artículo científico publicado en 2016

Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire

article

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

artículo científico publicado en 2010

Molecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell Repertoire

artículo científico publicado en 2014

Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy

artículo científico publicado en 2016

Multivariate Analysis Using High Definition Flow Cytometry Reveals Distinct T Cell Repertoires between the Fetal-Maternal Interface and the Peripheral Blood

artículo científico publicado en 2014

Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

artículo científico publicado en 2015

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

artículo científico publicado en 2009

Peptide length determines the outcome of TCR/peptide-MHCI engagement

artículo científico publicado en 2013

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

artículo científico publicado en 2018

Phase I trial of a CD8+ T-cell peptide epitope-based vaccine for infectious mononucleosis

artículo científico publicado en 2008

Potent T cell response to a class I-binding 13-mer viral epitope and the influence of HLA micropolymorphism in controlling epitope length

artículo científico publicado en 2004

Predictable alphabeta T-cell receptor selection toward an HLA-B*3501-restricted human cytomegalovirus epitope

artículo científico publicado en 2007

Preferential binding of unusually long peptides to MHC class I and its influence on the selection of target peptides for T cell recognition

artículo científico publicado en 2007

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity

artículo científico publicado en 2016

Promiscuous CTL recognition of viral epitopes on multiple human leukocyte antigens: biological validation of the proposed HLA A24 supertype

artículo científico publicado en 2003

Prophylactic and therapeutic adenoviral vector-based multivirus-specific T-cell immunotherapy for transplant patients.

artículo científico publicado en 2016

Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis).

artículo científico publicado en 2018

Reactivated CD4+Tm cells of T1D patients and siblings display an exaggerated effector phenotype with heightened sensitivity to activation-induced cell death

artículo científico publicado en 2014

Real-time determination of enantiomeric and isomeric content using photoelectron elliptical dichroism

artículo científico publicado en 2018

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

artículo científico publicado en 2013

Relationship of Chromosome Arm 10q Variants to Occurrence of Multiple Primary Melanoma in the Population-Based Genes, Environment, and Melanoma (GEM) Study

scientific article published on 17 December 2018

Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studies

artículo científico publicado en 2018

Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.

artículo científico publicado en 2016

Structural and biophysical determinants of αβ T-cell antigen recognition

artículo científico publicado en 2012

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

artículo científico publicado en 2012

Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy

artículo científico publicado en 2016

Sympathetic support of energy expenditure and sympathetic nervous system activity after gastric bypass surgery.

artículo científico publicado en 2013

Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo

artículo científico publicado en 2021

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells

artículo científico publicado en 2015

T cell antigen receptor recognition of antigen-presenting molecules

artículo científico

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

artículo científico publicado en 2018

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

artículo científico publicado en 2005

T-cell Receptor Specificity Maintained by Altered Thermodynamics

artículo científico publicado en 2013

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

artículo científico publicado en 2012

T-cell grit: large clonal expansions of virus-specific CD8+ T cells can dominate in the peripheral circulation for at least 18 years

artículo científico publicado en 2005

T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones

artículo científico publicado en 2016

TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope

artículo científico publicado en 2006

TCR deep sequencing of transgenic RAG-1-deficient mice reveals endogenous TCR recombination: a cause for caution.

artículo científico publicado en 2018

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

article

The immune checkpoint CD96 defines a distinct lymphocyte phenotype and is highly expressed on tumor-infiltrating T cells

scientific article published on 17 October 2018

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

artículo científico publicado en 2005

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

article

The impact of a large and frequent deletion in the human TCR β locus on antiviral immunity

artículo científico publicado en 2012

Tracking the T-cell repertoire after adoptive therapy

artículo científico publicado en 2017

Tracking the repertoire of human adult and neonatal T cells during ex vivo amplification

artículo científico publicado en 2012

Understanding the complexity and malleability of T-cell recognition

artículo científico

Widespread sequence variation in Epstein-Barr virus nuclear antigen 1 influences the antiviral T cell response

artículo científico publicado en 2008

β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure

artículo científico publicado en 2014

Lista de obras de John J Miles

A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics

A single autoimmune T cell receptor recognizes more than a million different peptides

Advances in T-cell epitope engineering

Allelic polymorphism in the T cell receptor and its impact on immune responses

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant

Anomalies in T Cell Function Are Associated With Individuals at Risk of Mycobacterium abscessus Complex Infection.

Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection

Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining

Antibody response to common human viruses is shaped by genetic factors

Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection

Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination

Bone marrow transplantation generates T cell-dependent control of myeloma in mice

CD8(+) T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

CTL recognition of a bulged viral peptide involves biased TCR selection

Coinfection with Human Cytomegalovirus Genetic Variants in Transplant Recipients and Its Impact on Antiviral T Cell Immune Reconstitution

Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells

Design, synthesis and evaluation of β-lactam antigenic peptide hybrids; unusual opening of the β-lactam ring in acidic media ⬇️

Differential pulsatile secretagogue control of GH secretion in healthy men ⬇️

Diversity of Rhizoctonia spp. Causing Foliar Blight on Brachiaria in Colombia and Evaluation of Brachiaria Genotypes for Foliar Blight Resistance

Endogenous presentation of CD8+ T cell epitopes from Epstein-Barr virus-encoded nuclear antigen 1.

Engineered T cell receptors and their potential in molecular medicine

Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells

Erratum: Tracking the T-cell repertoire after adoptive therapy

Exploring immunomodulation by endocrine changes in Lady Windermere syndrome

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.

HLA peptide length preferences control CD8+ T cell responses

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

Helminth Immunomodulation in Autoimmune Disease

High frequency of herpesvirus-specific clonotypes in the human T cell repertoire can remain stable over decades with minimal turnover

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

How the Cobra Got Its Flesh-Eating Venom: Cytotoxicity as a Defensive Innovation and Its Co-Evolution with Hooding, Aposematic Marking, and Spitting

Human CD141+ Dendritic Cell and CD1c+ Dendritic Cell Undergo Concordant Early Genetic Programming after Activation in Humanized Mice In Vivo

IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling

Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors

Immune drug discovery from venoms.

Immune parameters to consider when choosing T-cell receptors for therapy

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipients

Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) Web-Server.

Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

Molecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell Repertoire

Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy

Multivariate Analysis Using High Definition Flow Cytometry Reveals Distinct T Cell Repertoires between the Fetal-Maternal Interface and the Peripheral Blood

Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

Peptide length determines the outcome of TCR/peptide-MHCI engagement

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

Phase I trial of a CD8+ T-cell peptide epitope-based vaccine for infectious mononucleosis

Potent T cell response to a class I-binding 13-mer viral epitope and the influence of HLA micropolymorphism in controlling epitope length

Predictable alphabeta T-cell receptor selection toward an HLA-B*3501-restricted human cytomegalovirus epitope

Preferential binding of unusually long peptides to MHC class I and its influence on the selection of target peptides for T cell recognition

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity

Promiscuous CTL recognition of viral epitopes on multiple human leukocyte antigens: biological validation of the proposed HLA A24 supertype

Prophylactic and therapeutic adenoviral vector-based multivirus-specific T-cell immunotherapy for transplant patients.

Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis).

Reactivated CD4+Tm cells of T1D patients and siblings display an exaggerated effector phenotype with heightened sensitivity to activation-induced cell death

Real-time determination of enantiomeric and isomeric content using photoelectron elliptical dichroism

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

Relationship of Chromosome Arm 10q Variants to Occurrence of Multiple Primary Melanoma in the Population-Based Genes, Environment, and Melanoma (GEM) Study

Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studies