Lista de obras - Laura J Sharpe - Dominio Público Uruguay

A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes

artículo científico publicado en 2015

A lipidomic perspective on intermediates in cholesterol synthesis as indicators of disease status.

artículo científico publicado en 2014

Akt acutely activates the cholesterogenic transcription factor SREBP-2.

artículo científico publicado en 2011

Akt phosphorylates Sec24: new clues into the regulation of ER-to-Golgi trafficking.

artículo científico publicado en 2010

Antipsychotic drugs upregulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol.

artículo científico publicado en 2009

Approaches to investigate the role of signaling in ER-to-Golgi transport.

artículo científico publicado en 2008

Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt ⬇️

artículo científico publicado el 1 de octubre de 2012

Cholesterol homeostasis: How do cells sense sterol excess?

artículo científico publicado en 2016

Cholesterol sensing by the ABCG1 lipid transporter: Requirement of a CRAC motif in the final transmembrane domain

artículo científico publicado en 2015

Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

artículo científico publicado en 2016

DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme. ⬇️

artículo científico publicado en 2014

DHCR7: A vital enzyme switch between cholesterol and vitamin D production

artículo científico publicado en 2016

Desmosterol and DHCR24: unexpected new directions for a terminal step in cholesterol synthesis.

artículo científico

Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed

artículo científico publicado en 2014

Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1

artículo científico

Identifying Sterol Response Elements Within Promoters of Genes.

artículo científico publicado en 2017

Investigating signaling processes in membrane trafficking

artículo científico publicado en 2015

Is seladin-1 really a selective Alzheimer's disease indicator?

artículo científico

Navigating the Shallows and Rapids of Cholesterol Synthesis Downstream of HMGCR

artículo científico publicado en 2015

New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis.

artículo científico publicado en 2017

Oxysterols: Old Tale, New Twists.

artículo científico publicado en 2016

Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis.

artículo científico publicado en 2016

Post-translational control of the long and winding road to cholesterol

artículo científico publicado en 2020

Protein kinase A modulates the activity of a major human isoform of ABCG1 ⬇️

artículo científico publicado el 7 de agosto de 2012

Protein tyrosine phosphatase inhibition down-regulates ligand-induced ABCA1 expression.

artículo científico publicado en 2013

Rapamycin down-regulates LDL-receptor expression independently of SREBP-2.

artículo científico publicado en 2008

Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis

scientific article published on 20 December 2013

Sterols regulate 3β-hydroxysterol Δ24-reductase (DHCR24) via dual sterol regulatory elements: cooperative induction of key enzymes in lipid synthesis by Sterol Regulatory Element Binding Proteins.

artículo científico publicado en 2012

The Akt-SREBP nexus: cell signaling meets lipid metabolism.

artículo científico publicado en 2010

The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway.

scientific article published on 21 January 2014

The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.

artículo científico publicado en 2018

The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters

artículo científico publicado en 2015

The UPS and downs of cholesterol homeostasis.

artículo científico

The role of signalling in cellular cholesterol homeostasis

artículo científico publicado en 2013

The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis.

artículo científico publicado en 2014

The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally.

artículo científico publicado en 2015

Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally

artículo científico publicado en 2020

Lista de obras de Laura J Sharpe

A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes

A lipidomic perspective on intermediates in cholesterol synthesis as indicators of disease status.

Akt acutely activates the cholesterogenic transcription factor SREBP-2.

Akt phosphorylates Sec24: new clues into the regulation of ER-to-Golgi trafficking.

Antipsychotic drugs upregulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol.

Approaches to investigate the role of signaling in ER-to-Golgi transport.

Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt ⬇️

Cholesterol homeostasis: How do cells sense sterol excess?

Cholesterol sensing by the ABCG1 lipid transporter: Requirement of a CRAC motif in the final transmembrane domain

Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme. ⬇️

DHCR7: A vital enzyme switch between cholesterol and vitamin D production

Desmosterol and DHCR24: unexpected new directions for a terminal step in cholesterol synthesis.

Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed

Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1

Identifying Sterol Response Elements Within Promoters of Genes.

Investigating signaling processes in membrane trafficking

Is seladin-1 really a selective Alzheimer's disease indicator?

Navigating the Shallows and Rapids of Cholesterol Synthesis Downstream of HMGCR

New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis.

Oxysterols: Old Tale, New Twists.

Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis.

Post-translational control of the long and winding road to cholesterol

Protein kinase A modulates the activity of a major human isoform of ABCG1 ⬇️

Protein tyrosine phosphatase inhibition down-regulates ligand-induced ABCA1 expression.

Rapamycin down-regulates LDL-receptor expression independently of SREBP-2.

Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis

Sterols regulate 3β-hydroxysterol Δ24-reductase (DHCR24) via dual sterol regulatory elements: cooperative induction of key enzymes in lipid synthesis by Sterol Regulatory Element Binding Proteins.

The Akt-SREBP nexus: cell signaling meets lipid metabolism.

The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway.

The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.

The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters

The UPS and downs of cholesterol homeostasis.

The role of signalling in cellular cholesterol homeostasis

The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis.

The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally.

Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally