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Lista de obras de Elena Aikawa

18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis

artículo científico publicado en 2009

2020 Jeffrey M. Hoeg Award Lecture: Calcifying Extracellular Vesicles as Building Blocks of Microcalcifications in Cardiovascular Disorders

artículo científico publicado en 2020

3D Ultrasound: seeing is understanding-from imaging to pathophysiology to developing therapies in secondary MR.

artículo científico publicado en 2016

A Not-So-Little Role for Lipoprotein(a) in the Development of Calcific Aortic Valve Disease.

artículo científico publicado en 2015

A Rock and a Hard Place: Chiseling Away at the Multiple Mechanisms of Aortic Stenosis.

artículo científico publicado en 2017

A novel quantitative approach for eliminating sample-to-sample variation using a hue saturation value analysis program

artículo científico publicado en 2014

A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification

artículo científico publicado en 2016

Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.

artículo científico publicado en 2008

Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves

artículo científico publicado en 2001

Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation.

artículo científico publicado en 2009

Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease

artículo científico publicado en 2016

After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective From the International Society for Applied Cardiovascular Biology

An (Auto)Taxing Effort to Mechanistically Link Obesity and Calcific Aortic Valve Disease

artículo científico publicado en 2020

Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis

scientific article published on 16 September 2020

Aortic valve calcification predicts all-cause mortality independent of coronary calcification and severe stenosis

scientific article published on 08 July 2020

ApoC-III is a novel inducer of calcification in human aortic valves

artículo científico publicado en 2020

Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.

artículo científico publicado en 2009

Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation

artículo científico publicado en 2010

CD45 Expression in Mitral Valve Endothelial Cells After Myocardial Infarction.

artículo científico publicado en 2016

CROT (Carnitine O-Octanoyltransferase) Is a Novel Contributing Factor in Vascular Calcification via Promoting Fatty Acid Metabolism and Mitochondrial Dysfunction

artículo científico publicado en 2020

Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.

artículo científico publicado en 2014

Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.

artículo científico publicado en 2011

Calcific aortic valve stenosis: hard disease in the heart: A biomolecular approach towards diagnosis and treatment.

artículo científico publicado en 2017

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation.

artículo científico publicado en 2016

Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation, and Biomarkers in Cardiovascular Inflammation

artículo científico publicado en 2013

Cardiovascular calcification: an inflammatory disease

artículo científico publicado en 2011

Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery

artículo científico publicado en 2019

Cardiovascular calcification: current controversies and novel concepts.

artículo científico

Cardiovascular inflammation

artículo científico publicado en 2012

Cathepsin S As an Inhibitor of Cardiovascular Inflammation and Calcification in Chronic Kidney Disease

artículo científico publicado en 2017

Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials

scholarly article by Farouc A. Jaffer et al published April 2006 in Molecular imaging : official journal of the Society for Molecular Imaging

Cellular imaging of inflammation in atherosclerosis using magnetofluorescent nanomaterials

artículo científico publicado en 2006

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging

scientific article published on 03 October 2005

Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells

artículo científico publicado en 2006

Chronic hypoxia activates the Akt and beta-catenin pathways in human macrophages.

artículo científico publicado en 2009

Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site.

artículo científico publicado en 2004

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy

artículo científico publicado en 2008

Comparative Histopathological Analysis of Mitral Valves in Barlow Disease and Fibroelastic Deficiency

artículo científico publicado en 2016

Complex association of lipoprotein(a) with aortic stenosis

scientific article published on 21 February 2020

Controlled delivery of gold nanoparticle-coupled miRNA therapeutics <i>via</i> an injectable self-healing hydrogel

artículo científico publicado en 2021

Current Trends and Future Perspectives of State-of-the-Art Proteomics Technologies Applied to Cardiovascular Disease Research

artículo científico publicado en 2016

Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve.

artículo científico publicado en 2011

Cystathionine γ-lyase accelerates osteoclast differentiation: identification of a novel regulator of osteoclastogenesis by proteomic analysis

artículo científico publicado en 2013

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles.

artículo científico publicado en 2018

Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy.

artículo científico publicado en 2006

Dietary lipid lowering reduces tissue factor expression in rabbit atheroma.

artículo científico publicado en 1999

Differential miRNA Loading Underpins Dual Harmful and Protective Roles for Extracellular Vesicles in Atherogenesis

scientific article published on 01 February 2019

Diffusion spectrum MRI tractography reveals the presence of a complex network of residual myofibers in infarcted myocardium.

artículo científico publicado en 2009

Dimerization of sortilin regulates its trafficking to extracellular vesicles

artículo científico publicado en 2018

Directing valvular interstitial cell myofibroblast-like differentiation in a hybrid hydrogel platform

artículo científico publicado en 2014

Discoidin Domain Receptor-1 Regulates Calcific Extracellular Vesicle Release in Vascular Smooth Muscle Cell Fibrocalcific Response via Transforming Growth Factor-β Signaling.

artículo científico publicado en 2016

Double-edged sword of ALDH2 mutations: one polymorphism can both benefit and harm the cardiovascular system

artículo científico publicado en 2020

Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.

artículo científico publicado en 2007

Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.

artículo científico publicado en 2017

EVpedia: a community web portal for extracellular vesicles research

artículo científico publicado en 2014

Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo

artículo científico publicado en 2008

Editorial: Exploring the Frontiers of Regenerative Cardiovascular Medicine

Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases

Editorial: Insight in heart valve disease: 2021

artículo científico publicado en 2022

Effect of Losartan on Mitral Valve Changes After Myocardial Infarction

artículo científico publicado en 2017

Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets

scientific article published on 22 June 2021

Elastogenesis at the onset of human cardiac valve development

artículo científico publicado en 2013

Elastomeric Fibrous Hybrid Scaffold Supports In Vitro and In Vivo Tissue Formation

scientific article published on 05 June 2017

Endothelial progenitor cells as a sole source for ex vivo seeding of tissue-engineered heart valves.

artículo científico publicado en 2010

Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review

scientific article published on 01 January 2019

Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.

artículo científico publicado en 2018

Enrichment of calcifying extracellular vesicles using density-based ultracentrifugation protocol

artículo científico publicado en 2014

Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis.

artículo científico publicado en 2010

Extracellular Vesicles As Mediators of Cardiovascular Calcification

artículo científico publicado en 2017

Extracellular vesicles in cardiovascular calcification: expanding current paradigms.

artículo científico publicado en 2016

Extracellular vesicles in cardiovascular disease: focus on vascular calcification

artículo científico publicado en 2016

Extracellular vesicles in cardiovascular homeostasis and disease.

artículo científico publicado en 2018

F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images

Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata

artículo científico publicado en 2011

Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion.

artículo científico publicado en 2017

Flow Preservation of Umbilical Vein for Autologous Shunt and Cardiovascular Reconstruction.

artículo científico publicado en 2018

Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo

artículo científico publicado en 2007

Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques

artículo científico publicado en 2016

Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II

artículo científico publicado en 2009

Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field

artículo científico publicado en 2017

Harnessing Single-Cell RNA Sequencing to Better Understand How Diseased Cells Behave the Way They Do in Cardiovascular Disease

scientific article published on 17 December 2020

Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep.

artículo científico publicado en 2007

Heart Valve Disease: Challenges and New Opportunities

scientific article published on 22 October 2020

Histopathological assessment of calcification and inflammation of calcific aortic valves from patients with and without diabetes mellitus

artículo científico publicado en 2016

Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy

artículo científico publicado en 2001

Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2.

artículo científico publicado en 2006

Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering

artículo científico publicado en 2006

Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.

artículo científico publicado en 2009

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

artículo científico publicado en 2009

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.

artículo científico publicado en 2010

In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease

artículo científico publicado en 2017

In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation

artículo científico publicado en 2011

In vivo monitoring of function of autologous engineered pulmonary valve

artículo científico publicado en 2010

Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques

artículo científico publicado en 2011

Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo

artículo científico publicado en 2006

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

scientific article published on 01 July 2005

Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis

artículo científico publicado en 2012

Innate and adaptive immunity in cardiovascular calcification

artículo científico publicado en 2020

Interferon-γ Released by Activated CD8+ T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves.

artículo científico publicado en 2017

International Society for Extracellular Vesicles: Second Annual Meeting, 17-20 April 2013, Boston, MA (ISEV 2013).

artículo científico publicado en 2013

Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study

artículo científico publicado en 2010

Leukocyte-derived microparticles as proinflammatory mediators in atherosclerosis

artículo científico publicado en 2013

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.

artículo científico publicado en 1998

Lipid lowering promotes accumulation of mature smooth muscle cells expressing smooth muscle myosin heavy chain isoforms in rabbit atheroma

scientific article published on 01 November 1998

Lipoprotein(a) Induces Vesicular Cardiovascular Calcification Revealed With Single-Extracellular Vesicle Analysis

artículo científico publicado en 2022

Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

Look More Closely at the Valve

artículo científico publicado en 2011

Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

artículo científico publicado en 2007

Macrophage Heterogeneity Complicates Reversal of Calcification in Cardiovascular Tissues.

artículo científico publicado en 2017

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques

artículo científico publicado en 2013

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques

scientific article published on 17 October 2005

Medial and intimal calcification in chronic kidney disease: stressing the contributions.

artículo científico publicado en 2013

MicroRNA Extracellular Vesicle Stowaways in Cell-Cell Communication and Organ Crosstalk

scientific article published on 26 November 2019

MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms.

artículo científico publicado en 2013

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling

artículo científico publicado en 2017

Mitral Regurgitation After Percutaneous Mitral Valvuloplasty: Insights Into Mechanisms and Impact on Clinical Outcomes

scientific article published on 11 September 2020

Mitral Valve Adaptation to Isolated Annular Dilation: Insights Into the Mechanism of Atrial Functional Mitral Regurgitation.

artículo científico publicado en 2017

Mitral Valve Adaptation: Can We Win the Race?

artículo científico publicado en 2018

Mitral valve disease--morphology and mechanisms

artículo científico publicado en 2015

Mitral valve endothelial cells with osteogenic differentiation potential.

artículo científico publicado en 2010

Modifying vascular calcification in diabetes mellitus: contribution of O-GlcNAcylation.

artículo científico publicado en 2014

Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.

artículo científico publicado en 2009

Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia

artículo científico publicado en 2009

Molecular imaging insights into early inflammatory stages of arterial and aortic valve calcification

artículo científico publicado en 2011

Molecular imaging of innate immune cell function in transplant rejection

artículo científico publicado en 2009

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

artículo científico publicado en 2006

Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease.

artículo científico publicado en 2007

Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis

artículo científico publicado en 2008

Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.

artículo científico publicado en 2016

N-acetylglucosamine-1-Phosphate Transferase Suppresses Lysosomal Hydrolases in Dysfunctional Osteoclasts: A Potential Mechanism for Vascular Calcification

artículo científico publicado en 2015

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis.

artículo científico publicado en 2007

New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study

artículo científico publicado en 2017

Noninvasive Molecular Imaging of Disease Activity in Atherosclerosis

artículo científico publicado en 2016

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis

artículo científico publicado en 2006

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

artículo científico publicado en 2012

Notch signaling in cardiovascular disease and calcification.

artículo científico publicado en 2008

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor

artículo científico publicado en 2007

Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo

artículo científico publicado en 2007

Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation

artículo científico publicado en 2009

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

artículo científico publicado en 2016

Parathyroid hormone: critical bridge between bone metabolism and cardiovascular disease.

artículo científico publicado en 2014

Pioglitazone suppresses inflammation in vivo in murine carotid atherosclerosis: novel detection by dual-target fluorescence molecular imaging.

artículo científico publicado en 2010

Pitavastatin Reduces Inflammation in Atherosclerotic Plaques in Apolipoprotein E-Deficient Mice with Late Stage Renal Disease.

artículo científico publicado en 2015

Potential drug targets for calcific aortic valve disease.

artículo científico publicado en 2014

Progenitor cells confer plasticity to cardiac valve endothelium.

artículo científico

Quantification of Calcified Particles in Human Valve Tissue Reveals Asymmetry of Calcific Aortic Valve Disease Development

artículo científico publicado en 2016

Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis

artículo científico publicado en 2008

Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects

artículo científico publicado en 2019

Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries

artículo científico publicado en 2013

Revisiting cardiovascular calcification: A multifaceted disease requiring a multidisciplinary approach

artículo científico

Role of extracellular vesicles in de novo mineralization: an additional novel mechanism of cardiovascular calcification

artículo científico publicado en 2013

Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism

S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus

artículo científico publicado en 2020

Selective cathepsin S inhibition attenuates atherosclerosis in apolipoprotein E-deficient mice with chronic renal disease

artículo científico publicado en 2015

Selective inhibition of matrix metalloproteinase-13 increases collagen content of established mouse atherosclerosis

artículo científico publicado en 2011

Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction.

artículo científico publicado en 2002

Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.

artículo científico publicado en 2017

Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves

artículo científico publicado en 2018

Simplified syntheses of complex multifunctional nanomaterials

artículo científico publicado en 2008

Simulation of early calcific aortic valve disease in a 3D platform: A role for myofibroblast differentiation.

artículo científico publicado en 2016

Small entities with large impact: microcalcifications and atherosclerotic plaque vulnerability

artículo científico publicado en 2014

Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases.

artículo científico publicado en 2017

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

artículo científico publicado en 2016

Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.

artículo científico publicado en 2018

Standardization of Human Calcific Aortic Valve Disease Modeling Reveals Passage-Dependent Calcification

Statins suppress apolipoprotein CIII-induced vascular endothelial cell activation and monocyte adhesion

artículo científico publicado en 2012

Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development

artículo científico publicado en 2021

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

artículo científico publicado en 2000

The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development

artículo científico publicado en 2018

The antiproliferative cytostatic effects of a self-activating viridin prodrug

artículo científico publicado en 2009

The osteoclast-associated receptor (OSCAR) is a novel receptor regulated by oxidized low-density lipoprotein in human endothelial cells.

artículo científico publicado en 2011

The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells

artículo científico publicado en 2009

Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

artículo científico publicado en 2008

Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin.

artículo científico publicado en 2018

Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.

artículo científico publicado en 2008

Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries

artículo científico publicado en 2009

Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling

artículo científico publicado en 2019

Valve under the microscope: shining a light on emerging technologies elucidating disease mechanisms

artículo científico

Valvular interstitial cells suppress calcification of valvular endothelial cells

artículo científico publicado en 2015

Vasculitis: molecular imaging by targeting the inflammatory enzyme myeloperoxidase.

artículo científico publicado en 2011

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

artículo científico publicado en 2012

Visualizing novel concepts of cardiovascular calcification

artículo científico publicado en 2013

Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition

artículo científico publicado en 2022

Zooming in on the genesis of atherosclerotic plaque microcalcifications

artículo científico publicado en 2016

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