Lista de obras - Michael P Carty - Dominio Público Uruguay

Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation ⬇️

artículo científico publicado el 1 de noviembre de 2011

Analysis of mutations induced by replication of UV-damaged plasmid DNA in HeLa cell extracts

scientific article published on 01 January 1995

Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors.

artículo científico publicado en 2018

COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.

artículo científico publicado en 2012

Complete replication of plasmid DNA containing a single UV-induced lesion in human cell extracts

scientific article published on 01 April 1996

DNA polymerase alpha from HeLa cells synthesizes DNA with high fidelity in a reconstituted replication system

scientific article published on 01 October 1990

DNA polymerase eta, a key protein in translesion synthesis in human cells.

artículo científico publicado en 2010

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells

artículo científico publicado en 2013

Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition

artículo científico publicado en 2016

Doxorubicin induces the DNA damage response in cultured human mesenchymal stem cells.

artículo científico publicado en 2012

Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.

artículo científico publicado en 2011

Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin

artículo científico publicado en 2008

Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts.

artículo científico publicado en 2001

First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation towards normal and breast cancer cell lines.

artículo científico publicado en 2011

HeLa cell single-stranded DNA-binding protein increases the accuracy of DNA synthesis by DNA polymerase alpha in vitro.

artículo científico publicado en 1992

HuCOP1 contributes to the regulation of DNA repair in keratinocytes.

artículo científico publicado en 2016

In vitro replication and mutagenesis of a novel reversion vector with selective DNA damage in the supF gene.

artículo científico publicado en 2001

Insights into UV-induced apoptosis: ultrastructure, trichrome stain and spectral imaging

artículo científico publicado en 2002

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis

artículo científico publicado en 2009

N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines

artículo científico publicado en 2018

New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.

artículo científico publicado en 2010

One-pot double intramolecular homolytic aromatic substitution routes to dialicyclic ring fused imidazobenzimidazolequinones and preliminary analysis of anticancer activity

artículo científico publicado en 2010

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

artículo científico publicado en 2003

Selective Methylmagnesium Chloride Mediated Acetylations of Isosorbide: A Route to Powerful Nitric Oxide Donor Furoxans

artículo científico publicado en 2018

Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro ⬇️

artículo científico publicado el 1 de marzo de 1992

Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents.

artículo científico publicado en 2010

Synthesis by radical cyclization and cytotoxicity of highly potent bioreductive alicyclic ring fused [1,2-a]benzimidazolequinones

artículo científico publicado en 2007

The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.

artículo científico publicado en 2007

The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells.

artículo científico publicado en 2010

The morphological and spectral phenotype of apoptosis in HeLa cells varies following exposure to UV-C and the addition of inhibitors of ICE and CPP32.

artículo científico publicado en 1998

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

artículo científico publicado en 2006

UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.

artículo científico publicado en 2001

Lista de obras de Michael P Carty

Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation ⬇️

Analysis of mutations induced by replication of UV-damaged plasmid DNA in HeLa cell extracts

Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors.

COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.

Complete replication of plasmid DNA containing a single UV-induced lesion in human cell extracts

DNA polymerase alpha from HeLa cells synthesizes DNA with high fidelity in a reconstituted replication system

DNA polymerase eta, a key protein in translesion synthesis in human cells.

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells

Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition

Doxorubicin induces the DNA damage response in cultured human mesenchymal stem cells.

Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.

Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin

Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts.

First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation towards normal and breast cancer cell lines.

HeLa cell single-stranded DNA-binding protein increases the accuracy of DNA synthesis by DNA polymerase alpha in vitro.

HuCOP1 contributes to the regulation of DNA repair in keratinocytes.

In vitro replication and mutagenesis of a novel reversion vector with selective DNA damage in the supF gene.

Insights into UV-induced apoptosis: ultrastructure, trichrome stain and spectral imaging

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis

N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines

New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.

One-pot double intramolecular homolytic aromatic substitution routes to dialicyclic ring fused imidazobenzimidazolequinones and preliminary analysis of anticancer activity

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

Selective Methylmagnesium Chloride Mediated Acetylations of Isosorbide: A Route to Powerful Nitric Oxide Donor Furoxans

Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro ⬇️

Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents.

Synthesis by radical cyclization and cytotoxicity of highly potent bioreductive alicyclic ring fused [1,2-a]benzimidazolequinones

The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.

The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells.

The morphological and spectral phenotype of apoptosis in HeLa cells varies following exposure to UV-C and the addition of inhibitors of ICE and CPP32.

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.