Lista de obras -

A fluorescent approach for identifying P2X1 ligands

artículo científico publicado en 2015

A role for specific collagen motifs during wound healing and inflammatory response of fibroblasts in the teleost fish gilthead seabream.

artículo científico publicado en 2011

A simple bioconjugate attachment protocol for use in single molecule force spectroscopy experiments based on mixed self-assembled monolayers.

artículo científico publicado en 2012

A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides

artículo científico publicado en 2006

An Activating Mutation Reveals a Second Binding Mode of the Integrin α2 I Domain to the GFOGER Motif in Collagens ⬇️

artículo científico publicado en 2013

Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.

artículo científico publicado en 2018

Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions.

artículo científico publicado en 2008

Cellular response to collagen-elastin composite materials

scientific article published on 23 December 2018

Characterization of high affinity binding motifs for the discoidin domain receptor DDR2 in collagen

artículo científico publicado en 2008

Cleavage by MMP-13 renders VWF unable to bind to collagen but increases its platelet reactivity

artículo científico publicado en 2020

Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1 ⬇️

artículo científico publicado el 28 de octubre de 2010

Collagen-binding proteins: insights from the Collagen Toolkits

scientific article published on 13 September 2019

Collagen-induced platelet activation

artículo científico publicado en 2006

Collagen-platelet interactions: recognition and signalling

artículo científico publicado en 2003

Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

artículo científico publicado en 2006

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood

artículo científico publicado en 2012

Corrigendum to 'Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro' [Biochem. Pharmacol. 148 (2018) 288-297]

artículo científico publicado en 2018

Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF

Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI

artículo científico publicado en 2010

Crystallographic insight into collagen recognition by discoidin domain receptor 2

artículo científico publicado en 2009

Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2

artículo científico publicado en 2004

Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment

artículo científico publicado en 2006

Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions.

artículo científico publicado en 2017

Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation

artículo científico publicado en 2012

Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate.

artículo científico publicado en 2014

Evaluation of cell binding to collagen and gelatin: a study of the effect of 2D and 3D architecture and surface chemistry

artículo científico publicado en 2016

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.

artículo científico publicado en 2016

First analysis of a bacterial collagen-binding protein with collagen Toolkits: promiscuous binding of YadA to collagens may explain how YadA interferes with host processes

artículo científico publicado en 2010

Hydroxyproline Ring Pucker Causes Frustration of Helix Parameters in the Collagen Triple Helix

artículo científico publicado en 2015

Identification and structural analysis of type I collagen sites in complex with fibronectin fragments

artículo científico publicado en 2009

Identification of multiple potent binding sites for human leukocyte associated Ig-like receptor LAIR on collagens II and III.

artículo científico publicado en 2009

Identification of platelet function defects by multi-parameter assessment of thrombus formation

artículo científico publicado en 2014

Impact of UV- and carbodiimide-based crosslinking on the integrin-binding properties of collagen-based materials

scientific article published on 02 October 2019

Implications for Collagen Binding from the Crystallographic Structure of Fibronectin 6FnI1-2FnII7FnI

artículo científico publicado en 2010

Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex

artículo científico publicado en 2012

Integrin activation state determines selectivity for novel recognition sites in fibrillar collagens

artículo científico publicado en 2004

Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens

artículo científico publicado en 2008

Mapping of potent and specific binding motifs, GLOGEN and GVOGEA, for integrin α1β1 using collagen toolkits II and III.

artículo científico publicado en 2012

Measurement of the Interaction Between Recombinant I-domain from Integrin alpha 2 beta 1 and a Triple Helical Collagen Peptide with the GFOGER Binding Motif Using Molecular Force Spectroscopy

artículo científico publicado en 2013

NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization

artículo científico publicado en 2014

New insights into the DT40 B cell receptor cluster using a proteomic proximity labeling assay

artículo científico publicado en 2014

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

artículo científico publicado en 2011

Optimisation of UV irradiation as a binding site conserving method for crosslinking collagen-based scaffolds.

artículo científico publicado en 2015

Platelet adhesion to decorin but not collagen I correlates with the integrin α2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system

artículo científico publicado en 2011

Platelet integrin alpha2 I-domain specific antibodies produced via domain specific DNA vaccination combined with variable gene phage display

artículo científico publicado en 2005

Platelets amplify inflammation in arthritis via collagen-dependent microparticle production

artículo científico publicado en 2010

Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation

artículo científico publicado en 2011

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

artículo científico publicado en 2014

Production of calmodulin-tagged proteins in Drosophila Schneider S2 cells: a novel system for antigen production and phage antibody isolation

artículo científico publicado en 2006

Proline provides site-specific flexibility for in vivo collagen

artículo científico publicado en 2018

Rapid Synthesis of a Register-specific Heterotrimeric Type I Collagen Helix Encompassing the Integrin α2β1 Binding Site

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor

artículo científico publicado en 2015

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces

scientific article published on 07 June 2019

Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation

artículo científico publicado en 2009

Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.

artículo científico publicado en 2017

Structural basis for collagen recognition by the immune receptor OSCAR.

artículo científico publicado en 2015

Structural basis of sequence-specific collagen recognition by SPARC

artículo científico publicado en 2008

Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

artículo científico publicado en 2012

Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling

artículo científico publicado en 2019

Structure of the integrin alpha2beta1-binding collagen peptide

artículo científico publicado en 2004

Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood

artículo científico publicado en 2010

The effect of purity upon the triple-helical stability of collagenous peptides

artículo científico publicado en 2011

The effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function

artículo científico publicado en 2004

The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix

artículo científico publicado en 2004

The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding.

artículo científico publicado en 2016

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression

artículo científico publicado en 2003

The properties conferred upon triple-helical collagen-mimetic peptides by the presence of cysteine residues.

artículo científico publicado en 2012

The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage

artículo científico publicado en 2014

The streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen

artículo científico publicado en 2010

The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen

artículo científico publicado en 2016

Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites

artículo científico publicado en 2018

Unique charge-dependent constraint on collagen recognition by integrin α10β1.

artículo científico publicado en 2016

Use of synthetic peptides to locate novel integrin alpha2beta1-binding motifs in human collagen III.

artículo científico publicado en 2005

Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner.

artículo científico publicado en 2015

alpha 11beta 1 integrin recognizes the GFOGER sequence in interstitial collagens

artículo científico publicado en 2002

Lista de obras de

A fluorescent approach for identifying P2X1 ligands

A role for specific collagen motifs during wound healing and inflammatory response of fibroblasts in the teleost fish gilthead seabream.

A simple bioconjugate attachment protocol for use in single molecule force spectroscopy experiments based on mixed self-assembled monolayers.

A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides

An Activating Mutation Reveals a Second Binding Mode of the Integrin α2 I Domain to the GFOGER Motif in Collagens ⬇️

Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.

Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions.

Cellular response to collagen-elastin composite materials

Characterization of high affinity binding motifs for the discoidin domain receptor DDR2 in collagen

Cleavage by MMP-13 renders VWF unable to bind to collagen but increases its platelet reactivity

Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1 ⬇️

Collagen-binding proteins: insights from the Collagen Toolkits

Collagen-induced platelet activation

Collagen-platelet interactions: recognition and signalling

Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood

Corrigendum to 'Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro' [Biochem. Pharmacol. 148 (2018) 288-297]

Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF

Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI

Crystallographic insight into collagen recognition by discoidin domain receptor 2

Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2

Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment

Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions.

Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation

Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate.

Evaluation of cell binding to collagen and gelatin: a study of the effect of 2D and 3D architecture and surface chemistry

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.

First analysis of a bacterial collagen-binding protein with collagen Toolkits: promiscuous binding of YadA to collagens may explain how YadA interferes with host processes

Hydroxyproline Ring Pucker Causes Frustration of Helix Parameters in the Collagen Triple Helix

Identification and structural analysis of type I collagen sites in complex with fibronectin fragments

Identification of multiple potent binding sites for human leukocyte associated Ig-like receptor LAIR on collagens II and III.

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Impact of UV- and carbodiimide-based crosslinking on the integrin-binding properties of collagen-based materials

Implications for Collagen Binding from the Crystallographic Structure of Fibronectin 6FnI1-2FnII7FnI

Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex

Integrin activation state determines selectivity for novel recognition sites in fibrillar collagens

Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens

Mapping of potent and specific binding motifs, GLOGEN and GVOGEA, for integrin α1β1 using collagen toolkits II and III.

Measurement of the Interaction Between Recombinant I-domain from Integrin alpha 2 beta 1 and a Triple Helical Collagen Peptide with the GFOGER Binding Motif Using Molecular Force Spectroscopy

NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization

New insights into the DT40 B cell receptor cluster using a proteomic proximity labeling assay

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

Optimisation of UV irradiation as a binding site conserving method for crosslinking collagen-based scaffolds.

Platelet adhesion to decorin but not collagen I correlates with the integrin α2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system

Platelet integrin alpha2 I-domain specific antibodies produced via domain specific DNA vaccination combined with variable gene phage display

Platelets amplify inflammation in arthritis via collagen-dependent microparticle production

Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

Production of calmodulin-tagged proteins in Drosophila Schneider S2 cells: a novel system for antigen production and phage antibody isolation

Proline provides site-specific flexibility for in vivo collagen

Rapid Synthesis of a Register-specific Heterotrimeric Type I Collagen Helix Encompassing the Integrin α2β1 Binding Site

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces

Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation

Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.

Structural basis for collagen recognition by the immune receptor OSCAR.

Structural basis of sequence-specific collagen recognition by SPARC

Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling

Structure of the integrin alpha2beta1-binding collagen peptide

Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood

The effect of purity upon the triple-helical stability of collagenous peptides

The effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function

The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix

The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding.

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression

The properties conferred upon triple-helical collagen-mimetic peptides by the presence of cysteine residues.

The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage

The streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen

The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen

Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites

Unique charge-dependent constraint on collagen recognition by integrin α10β1.

Use of synthetic peptides to locate novel integrin alpha2beta1-binding motifs in human collagen III.

Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner.

alpha 11beta 1 integrin recognizes the GFOGER sequence in interstitial collagens