Lista de obras - Timothy Tree - Dominio Público Uruguay

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

artículo científico publicado en 2016

A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop.

artículo científico publicado en 2006

Allograft-specific cytokine profiles associate with clinical outcome after islet cell transplantation

artículo científico publicado en 2008

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

artículo científico publicado en 2004

Autoreactive T cells in human type 1 diabetes.

artículo científico publicado en 2004

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

scientific article published on 03 July 2013

CTLs are targeted to kill ? cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

artículo científico publicado en 2009

Circulating T follicular helper cell and regulatory T cell frequencies are influenced by B cell depletion in patients with granulomatosis with polyangiitis.

artículo científico publicado en 2013

Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity

artículo científico publicado en 2013

Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls

artículo científico publicado en 2011

Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop

artículo científico publicado en 2003

Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.

artículo científico publicado en 2005

Enhancing the sensitivity of assays to detect T cell reactivity: the effect of cell separation and cryopreservation media

scientific article published on 01 December 2004

Generation of human islet-specific regulatory T cells by TCR gene transfer

artículo científico publicado en 2017

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.

artículo científico publicado en 2005

HLA class I epitope discovery in type 1 diabetes: independent and reproducible identification of proinsulin epitopes of CD8 T cells--report of the IDS T Cell Workshop Committee

artículo científico publicado en 2006

HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65.

artículo científico publicado en 2004

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors

artículo científico publicado en 2017

Identifying the 'Achilles Heel' of type 1 diabetes

artículo científico publicado en 2020

Immune modulation in humans: implications for type 1 diabetes mellitus.

artículo científico publicado en 2014

Immunological biomarkers for the development and progression of type 1 diabetes

artículo científico publicado en 2018

Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes

scientific article published on 01 December 2008

Mesenchymal stromal cells as a means of controlling pathological T-cell responses in allogeneic islet transplantation.

artículo científico

Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.

artículo científico publicado en 2017

Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner.

artículo científico publicado en 2018

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

artículo científico publicado en 2015

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death

scientific journal article

Persistent C-peptide is associated with reduced hypoglycaemia but not HbA1c in adults with longstanding Type 1 diabetes: evidence for lack of intensive treatment in UK clinical practice?

artículo científico publicado en 2019

Phenotypic Complexity of the Human Regulatory T Cell Compartment Revealed by Mass Cytometry

artículo científico publicado en 2015

Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture

artículo científico publicado en 2008

Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors

artículo científico publicado en 2013

Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells

artículo científico publicado en 2003

Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules

scientific article published on 09 April 2003

Reconstruction of a pathway of antigen processing and class II MHC peptide capture.

artículo científico publicado en 2007

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

artículo científico publicado en 2016

Regulatory T cell dysfunction in type 1 diabetes: what's broken and how can we fix it?

artículo científico publicado en 2017

Resistance to Onchocerca volvulus: Differential Cellular and Humoral Responses to a Recombinant Antigen, OvMBP20/11

article

Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2.

artículo científico publicado en 2015

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis.

artículo científico publicado en 2016

The novel cuticular collagen Ovcol-1 of Onchocerca volvulus is preferentially recognized by immunoglobulin G3 from putatively immune individuals.

artículo científico publicado en 1997

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

artículo científico publicado en 2020

Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.

artículo científico publicado en 2012

Lista de obras de Timothy Tree

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop.

Allograft-specific cytokine profiles associate with clinical outcome after islet cell transplantation

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

Autoreactive T cells in human type 1 diabetes.

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

CTLs are targeted to kill ? cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

Circulating T follicular helper cell and regulatory T cell frequencies are influenced by B cell depletion in patients with granulomatosis with polyangiitis.

Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity

Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls

Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop

Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.

Enhancing the sensitivity of assays to detect T cell reactivity: the effect of cell separation and cryopreservation media

Generation of human islet-specific regulatory T cells by TCR gene transfer

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.

HLA class I epitope discovery in type 1 diabetes: independent and reproducible identification of proinsulin epitopes of CD8 T cells--report of the IDS T Cell Workshop Committee

HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65.

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors

Identifying the 'Achilles Heel' of type 1 diabetes

Immune modulation in humans: implications for type 1 diabetes mellitus.

Immunological biomarkers for the development and progression of type 1 diabetes

Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes

Mesenchymal stromal cells as a means of controlling pathological T-cell responses in allogeneic islet transplantation.

Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.

Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner.

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death

Persistent C-peptide is associated with reduced hypoglycaemia but not HbA1c in adults with longstanding Type 1 diabetes: evidence for lack of intensive treatment in UK clinical practice?

Phenotypic Complexity of the Human Regulatory T Cell Compartment Revealed by Mass Cytometry

Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture

Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors

Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells

Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules

Reconstruction of a pathway of antigen processing and class II MHC peptide capture.

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

Regulatory T cell dysfunction in type 1 diabetes: what's broken and how can we fix it?

Resistance to Onchocerca volvulus: Differential Cellular and Humoral Responses to a Recombinant Antigen, OvMBP20/11

Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2.

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis.

The novel cuticular collagen Ovcol-1 of Onchocerca volvulus is preferentially recognized by immunoglobulin G3 from putatively immune individuals.

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.