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Lista de obras de Robin J.M. Franklin

A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System

artículo científico publicado en 2018

A map of transcriptional heterogeneity and regulatory variation in human microglia

scientific article published on 03 June 2021

Abnormal myelinogenesis in the central nervous system of the VF mutant rat with recoverable tremor.

artículo científico publicado en 2012

Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis

scientific article published on 21 June 2008

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

artículo científico publicado en 2008

Ageing stem and progenitor cells: implications for rejuvenation of the central nervous system

artículo científico publicado en 2013

Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination

artículo científico publicado en 2019

Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell Remyelination

artículo científico publicado en 2015

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression

artículo científico publicado en 2014

Autologous olfactory glial cell transplantation is reliable and safe in naturally occurring canine spinal cord injury.

artículo científico publicado en 2005

Autologous olfactory mucosal cell transplants in clinical spinal cord injury: a randomized double-blinded trial in a canine translational model

artículo científico publicado en 2012

Auxetic nuclei in embryonic stem cells exiting pluripotency.

artículo científico publicado en 2014

Axon loss in multiple sclerosis.

artículo científico publicado en 1998

Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy

artículo científico publicado en 2016

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

artículo científico publicado en 2006

CNS Remyelination and the Innate Immune System

artículo científico publicado en 2016

CNS axons retain their competence for myelination throughout life.

artículo científico publicado en 2004

CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

artículo científico publicado en 2010

Calponin is expressed by fibroblasts and meningeal cells but not olfactory ensheathing cells in the adult peripheral olfactory system.

artículo científico

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS

scientific article published on 01 October 2006

Cell therapy for spinal cord injuries: what is really going on?

artículo científico publicado en 2014

Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury.

artículo científico publicado en 2017

Clinical canine spinal cord injury provides an opportunity to examine the issues in translating laboratory techniques into practical therapy.

artículo científico publicado en 2006

Clinical implications of myelin regeneration in the central nervous system

artículo científico publicado en 2017

Comparison of cell populations derived from canine olfactory bulb and olfactory mucosal cultures.

artículo científico

Congenital unilateral absence of the corticospinal tract in a Siamese cat.

artículo científico publicado en 2007

Contrasting effects of basic fibroblast growth factor and epidermal growth factor on mouse neonatal olfactory mucosa cells.

artículo científico publicado en 2007

Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system.

artículo científico publicado en 2006

Current status of myelin replacement therapies in multiple sclerosis.

artículo científico

Debris clearance by microglia: an essential link between degeneration and regeneration.

artículo científico publicado en 2009

Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration

artículo científico publicado en 2015

Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation.

artículo científico publicado en 2011

Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline

artículo científico publicado en 2016

Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination

scientific article published on 26 July 2005

Differentiation of the O-2A progenitor cell line CG-4 into oligodendrocytes and astrocytes following transplantation into glia-deficient areas of CNS white matter.

artículo científico publicado en 1995

Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain

artículo científico publicado en 2022

Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination.

artículo científico publicado en 1999

Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity?

scientific article published on 10 April 2019

Do olfactory glia have advantages over Schwann cells for CNS repair?

artículo científico publicado el 1 de diciembre de 1997

Do your glial cells make you clever?

artículo científico publicado en 2013

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

scientific journal article

Effects of pre- versus post-anaesthetic buprenorphine on propofol-anaesthetized rats.

artículo científico publicado en 2005

Efficient Remyelination Requires DNA Methylation

artículo científico publicado en 2017

Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen.

artículo científico publicado en 2011

Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) via β1 Integrin.

artículo científico publicado en 2016

FGF but not EGF induces phosphorylation of the cAMP response element binding protein in olfactory mucosa-derived cell cultures.

artículo científico publicado en 2010

Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS.

artículo científico publicado en 2006

Fibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions.

artículo científico publicado en 2015

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

artículo científico publicado el 1 de enero de 2013

Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency

artículo científico publicado en 2012

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage

artículo científico publicado en 2016

Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.

artículo científico publicado en 2011

Glia Disease and Repair-Remyelination

artículo científico publicado en 2015

Glial cell transplants that are subsequently rejected can be used to influence regeneration of glial cell environments in the CNS

artículo científico publicado en 1995

Hereditary ataxia, myokymia and neuromyotonia in Jack Russell terriers

scientific article published on 01 August 2012

High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology.

scientific article published on 31 October 2013

Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS.

artículo científico publicado en 2004

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.

artículo científico publicado en 2011

Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination.

artículo científico publicado en 2013

Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes

artículo científico publicado en 2010

Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells

artículo científico publicado en 2018

Isolation and long-term expansion of functional, myelinating oligodendrocyte progenitor cells from neonatal rat brain.

artículo científico publicado en 2014

Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells

artículo científico publicado en 2015

LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination.

artículo científico publicado en 2017

Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system

artículo científico publicado el 15 de octubre de 1997

MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter.

artículo científico publicado en 2016

Macrophages and CNS remyelination

artículo científico

Magnetic resonance imaging of functional Schwann cell transplants labelled with magnetic microspheres.

artículo científico publicado en 2006

Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy.

artículo científico publicado en 2010

Mechanical environment modulates biological properties of oligodendrocyte progenitor cells.

artículo científico publicado en 2012

Mechanisms of CNS remyelination--the key to therapeutic advances.

artículo científico publicado en 2005

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

artículo científico publicado en 2014

Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination.

artículo científico publicado en 2005

Multiple sclerosis genetics

artículo científico publicado en 2014

Mutations in genes causing human familial isolated hyperparathyroidism do not account for hyperparathyroidism in Keeshond dogs

scientific article published on 08 December 2006

Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

artículo científico publicado en 2006

Myelin regeneration in multiple sclerosis: targeting endogenous stem cells

artículo científico publicado en 2011

Myelin regeneration: a recapitulation of development?

artículo científico publicado en 2011

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

artículo científico publicado en 2009

Myokymia and neuromyotonia in veterinary medicine: a comparison with peripheral nerve hyperexcitability syndrome in humans.

artículo científico publicado en 2013

Nasal and frontal sinus mucosa of the adult dog contain numerous olfactory sensory neurons and ensheathing glia.

artículo científico publicado en 2005

Neural Precursor Cells Cultured at Physiologically Relevant Oxygen Tensions Have a Survival Advantage Following Transplantation

artículo científico publicado el 15 de mayo de 2013

Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes

artículo científico publicado en 2013

Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.

artículo científico publicado en 2008

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

artículo científico publicado el 12 de diciembre de 2011

Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis

artículo científico publicado en 2013

Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors

artículo científico publicado en 2015

Neuronal vulnerability and multilineage diversity in multiple sclerosis

scientific article published on 17 July 2019

Neuroprotection and repair in multiple sclerosis

artículo científico publicado el 2 de octubre de 2012

Neuroscience. The mysteries of myelin unwrapped.

artículo científico publicado en 2004

Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.

artículo científico publicado en 2004

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

artículo científico publicado en 2010

Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS

scientific article published on 10 January 2006

Oligodendrocyte progenitors: adult stem cells of the central nervous system?

artículo científico

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity

artículo científico publicado en 2018

Oligodendroglial pathology in the development of myelin breakdown in the dmy mutant rat

artículo científico publicado el 9 de marzo de 2011

Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination

artículo científico publicado en 2008

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

artículo científico publicado en 2017

Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis.

artículo científico publicado en 2013

Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes.

artículo científico publicado en 2015

Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination.

artículo científico publicado en 2004

Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination.

artículo científico publicado en 2016

Promoting remyelination in multiple sclerosis by endogenous adult neural stem/precursor cells: defining cellular targets.

artículo científico publicado en 2007

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

artículo científico publicado en 2009

Reconstruction of the glia limitans by sub-arachnoid transplantation of astrocyte-enriched cultures

artículo científico publicado en 1995

Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease.

artículo científico publicado en 2017

Regenerating CNS myelin - from mechanisms to experimental medicines.

artículo científico publicado en 2017

Regenerative Medicines for Remyelination: From Aspiration to Reality

artículo científico publicado en 2015

Regulatory T cells promote myelin regeneration in the central nervous system.

artículo científico publicado en 2017

Rejuvenation of Regeneration in the Aging Central Nervous System

artículo científico publicado el 6 de enero de 2012

Remyelination - An effective means of neuroprotection.

scientific article published on 16 June 2009

Remyelination by transplanted olfactory ensheathing cells.

artículo científico publicado en 2003

Remyelination: the true regeneration of the central nervous system.

artículo científico

Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells

artículo científico publicado en 1993

Response of olfactory ensheathing cells to the degeneration and regeneration of the peripheral olfactory system and the involvement of the neuregulins

artículo científico publicado en 2004

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

artículo científico publicado en 2015

Retinoid X receptors as a potential avenue for regenerative medicine in multiple sclerosis

artículo científico publicado en 2011

Schwann cell precursors: a favourable cell for myelin repair in the Central Nervous System.

artículo científico publicado en 2007

Schwann cell remyelination is restricted to astrocyte-deficient areas after transplantation into demyelinated adult rat brain

scientific article published on 01 June 2000

Schwann cells transplanted into normal and X-irradiated adult white matter do not migrate extensively and show poor long-term survival.

artículo científico publicado en 2000

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

artículo científico publicado en 2019

Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination.

artículo científico publicado en 2015

Special issue on stem cells: "the end of the beginning".

artículo científico publicado en 2014

Stem cell treatments and multiple sclerosis

artículo científico publicado en 2010

Stem cells, progenitors and myelin repair.

artículo científico publicado en 2005

Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice.

artículo científico publicado en 2017

Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS

scientific article published on 01 November 2004

The Brown Animal Sanatory Institution--historical lessons for the present?

artículo científico publicado en 2000

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury

artículo científico publicado en 2015

The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination

artículo científico publicado en 2014

The VF rat with abnormal myelinogenesis has a mutation in Dopey1.

artículo científico publicado en 2014

The biology of CNS remyelination: the key to therapeutic advances.

artículo científico publicado en 2008

The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelination

scientific article published on 04 February 2020

The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche.

artículo científico publicado en 2013

The phagocytic capacity of neurones

scientific article published on 01 May 2007

The translational biology of remyelination: past, present, and future

artículo científico

Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors

artículo científico publicado en 2019

Type 1 astrocytes fail to inhibit Schwann cell remyelination of CNS axons in the absence of cells of the O-2A lineage.

artículo científico publicado en 1992

Tyrosine kinases: maiming myelin in leprosy

scientific article published on 01 August 2006

Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin

artículo científico publicado en 2016

Up-regulation of oligodendrocyte precursor cell alphaV integrin and its extracellular ligands during central nervous system remyelination.

artículo científico publicado en 2009

Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation

artículo científico publicado en 2015

What roles do growth factors play in CNS remyelination?

artículo científico publicado en 2001