Lista de obras - Doron Merkler - Dominio Público Uruguay

Aggravation of viral hepatitis by platelet-derived serotonin

artículo científico publicado en 2008

B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.

artículo científico publicado en 2016

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice

scientific article published on 01 June 2019

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection

artículo científico publicado en 2016

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

scientific article published on 09 September 2019

Clival chordoma: a single-centre outcome analysis

artículo científico publicado en 2017

Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report.

artículo científico publicado en 2018

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior ⬇️

artículo científico publicado el 17 de enero de 2012

Enhanced Voluntary Exercise Improves Functional Recovery following Spinal Cord Injury by Impacting the Local Neuroglial Injury Response and Supporting the Rewiring of Supraspinal Circuits

artículo científico publicado en 2018

Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity

artículo científico publicado en 2020

Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.

artículo científico publicado en 2018

Extralymphatic virus sanctuaries as a consequence of potent T-cell activation

artículo científico publicado en 2007

Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements

scientific article published on 30 August 2018

Germline PMS2 and somatic POLE exonuclease mutations cause hypermutability of the leading DNA strand in biallelic mismatch repair deficiency syndrome brain tumours.

artículo científico publicado en 2017

Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells

artículo científico publicado en 2014

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.

artículo científico publicado en 2018

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis

artículo científico publicado en 2022

IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system

artículo científico publicado en 2011

Immunological mechanism of action and clinical profile of disease-modifying treatments in multiple sclerosis

artículo científico publicado en 2014

In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology

artículo científico publicado en 2016

Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients

artículo científico publicado en 2017

Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers

artículo científico publicado en 2013

Interferon-driven deletion of antiviral B cells at the onset of chronic infection.

artículo científico publicado en 2016

Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever.

artículo científico publicado en 2017

Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis

artículo científico publicado en 2012

Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses.

artículo científico publicado en 2016

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

artículo científico publicado en 2007

Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue

artículo científico publicado en 2014

Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model

artículo científico publicado en 2016

Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity

artículo científico publicado en 2018

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping

artículo científico publicado en 2018

Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE)

artículo científico publicado en 2016

Oxysterols regulate encephalitogenic CD4(+) T cell trafficking during central nervous system autoimmunity

artículo científico publicado en 2014

PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

artículo científico publicado en 2021

Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling

artículo científico publicado en 2021

Rapid induction of autoantibodies against Nogo‐A and MOG in the absence of an encephalitogenic T cell response: implication for immunotherapeutic approaches in neurological diseases ⬇️

artículo científico publicado el 16 de octubre de 2003

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

artículo científico publicado en 2015

Recurrent multiple CNS hemangioblastomas with VHL disease treated with pazopanib: a case report and literature review

artículo científico publicado en 2015

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

artículo científico publicado en 2017

Resident-Memory T Cells in Tissue-Restricted Immune Responses: For Better or Worse?

article

STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells.

artículo científico publicado en 2017

Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance

scientific article published on 01 April 2020

T cell-dependence of Lassa fever pathogenesis

artículo científico publicado en 2010

TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells

artículo científico publicado en 2016

Targeted ablation of oligodendrocytes triggers axonal damage

artículo científico publicado en 2011

The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs.

artículo científico publicado en 2017

The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8 T cells

artículo científico publicado en 2018

Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia

artículo científico publicado en 2012

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

artículo científico publicado en 2015

[CORRECTION] High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.

artículo científico publicado en 2018

pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion

scientific article published on 31 October 2016

Lista de obras de Doron Merkler

Aggravation of viral hepatitis by platelet-derived serotonin

B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

Clival chordoma: a single-centre outcome analysis

Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report.

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior ⬇️

Enhanced Voluntary Exercise Improves Functional Recovery following Spinal Cord Injury by Impacting the Local Neuroglial Injury Response and Supporting the Rewiring of Supraspinal Circuits

Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity

Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.

Extralymphatic virus sanctuaries as a consequence of potent T-cell activation

Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements

Germline PMS2 and somatic POLE exonuclease mutations cause hypermutability of the leading DNA strand in biallelic mismatch repair deficiency syndrome brain tumours.

Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis

IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system

Immunological mechanism of action and clinical profile of disease-modifying treatments in multiple sclerosis

In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology

Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients

Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers

Interferon-driven deletion of antiviral B cells at the onset of chronic infection.

Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever.

Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis

Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses.

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue

Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model

Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping

Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE)

Oxysterols regulate encephalitogenic CD4(+) T cell trafficking during central nervous system autoimmunity

PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling

Rapid induction of autoantibodies against Nogo‐A and MOG in the absence of an encephalitogenic T cell response: implication for immunotherapeutic approaches in neurological diseases ⬇️

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

Recurrent multiple CNS hemangioblastomas with VHL disease treated with pazopanib: a case report and literature review

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

Resident-Memory T Cells in Tissue-Restricted Immune Responses: For Better or Worse?

STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells.

Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance

T cell-dependence of Lassa fever pathogenesis

TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells

Targeted ablation of oligodendrocytes triggers axonal damage

The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs.

The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8 T cells

Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

[CORRECTION] High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.

pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion