Lista de obras - Thomas Grewal - Dominio Público Uruguay

Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells

artículo científico publicado en 2016

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

artículo científico publicado en 2017

Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet

scientific article published in PLoS ONE

Annexin A6 - a multifunctional scaffold in cell motility

artículo científico publicado en 2017

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.

artículo científico publicado en 2015

Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells

artículo científico publicado en 2019

Annexin A6 in the liver: From the endocytic compartment to cellular physiology

artículo científico publicado en 2016

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation ⬇️

artículo científico publicado el 16 de julio de 2012

Annexin A6 is an organizer of membrane microdomains to regulate receptor localization and signalling

artículo científico publicado en 2011

Annexin A6 is highly abundant in monocytes of obese and type 2 diabetic individuals and is downregulated by adiponectin in vitro

scientific article published on July 2009

Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

scientific article published on 29 October 2019

Annexin A6 protein is downregulated in human hepatocellular carcinoma.

artículo científico publicado en 2016

Annexin A6 regulates adipocyte lipid storage and adiponectin release

artículo científico publicado en 2016

Annexin A6 regulates interleukin-2-mediated T-cell proliferation

artículo científico publicado en 2016

Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity

artículo científico publicado en 2005

Annexin A6-Linking Ca(2+) signaling with cholesterol transport.

artículo científico publicado en 2010

Annexin A6-balanced late endosomal cholesterol controls influenza A replication and propagation

artículo científico publicado en 2013

Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex

artículo científico publicado en 2007

Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi

artículo científico publicado en 2008

Annexin A6-regulator of the EGFR/Ras signalling pathway and cholesterol homeostasis

artículo científico publicado en 2010

Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment

artículo científico publicado en 2000

Annexins - insights from knockout mice.

artículo científico publicado en 2016

Annexins - scaffolds modulating PKC localization and signaling

artículo científico publicado en 2014

Annexins and endosomal signaling

artículo científico publicado en 2014

Annexins in cell migration and adhesion.

artículo científico publicado en 2017

Annexins--modulators of EGF receptor signalling and trafficking

artículo científico publicado en 2009

Annexins-Coordinators of Cholesterol Homeostasis in Endocytic Pathways.

artículo científico publicado en 2018

Annexins: Ca2+ Effectors Determining Membrane Trafficking in the Late Endocytic Compartment.

artículo científico publicado en 2017

Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics

artículo científico publicado en 2024

Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes

artículo científico publicado en 2015

Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis

artículo científico publicado en 2005

Casein Kinase 2 Is a Novel Regulator of the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) Trafficking

artículo científico publicado en 2015

Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux

artículo científico publicado en 2011

Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.

artículo científico publicado en 2002

Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.

artículo científico publicado en 2014

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function.

artículo científico publicado en 2011

Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes

artículo científico publicado en 2013

Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes

artículo científico publicado en 2018

Desialylated LDL uptake in human and mouse macrophages can be mediated by a lectin receptor

scientific article published on 01 March 1996

Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP).

artículo científico publicado en 2004

Differential Regulation of RasGAPs in Cancer.

artículo científico publicado en 2011

Differential involvement of H- and K-Ras in Raf-1 activation determines the role of calmodulin in MAPK signaling.

artículo científico publicado en 2009

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling

artículo científico publicado en 2012

Diverse Roles of Annexin A6 in Triple-Negative Breast Cancer Diagnosis, Prognosis and EGFR-Targeted Therapies

artículo científico publicado en 2020

Editorial [ Hot Topic:New Methodology and Approaches to Intracellular Lipid Transport in Atherosclerosis and Cardiovascular Disease (Guest Editors: Basil D. Roufogalis and Thomas Grewal)]

scientific article published on 01 February 2012

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.

artículo científico publicado en 2015

Expression of γ-IFN responsive genes in scavenger receptor over-expressing monocytes is associated with xanthomatosis ⬇️

artículo científico publicado el 1 de junio de 1998

Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations

artículo científico publicado en 2011

Functional implications of plasma membrane condensation for T cell activation

artículo científico publicado en 2008

GTPases Rac1 and Ras Signaling from Endosomes

artículo científico publicado en 2018

Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate-induced apoptosis

scholarly article by Seher Balaban et al published September 2018 in Molecular Oncology

High density lipoprotein-induced signaling of the MAPK pathway involves scavenger receptor type BI-mediated activation of Ras.

artículo científico publicado en 2003

Highlight: annexins in health and disease

scientific article published on 01 October 2016

Hydrophobic and basic domains target proteins to lipid droplets

artículo científico publicado en 2009

Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets

artículo científico publicado en 2006

Identification of a gamma-interferon-responsive element in the promoter of the human macrophage scavenger receptor A gene.

artículo científico publicado en 2001

Identification of dual PPARα/γ agonists and their effects on lipid metabolism.

artículo científico publicado en 2015

Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene

artículo científico publicado en 2017

Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.

artículo científico publicado en 2004

Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells.

artículo científico publicado en 2005

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells

artículo científico publicado en 2013

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

artículo científico publicado en 2008

Interleukins in glioblastoma pathophysiology: implications for therapy.

artículo científico

Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

artículo científico publicado en 2012

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

artículo científico publicado en 2018

Late endocytic compartments are major sites of annexin VI localization in NRK fibroblasts and polarized WIF-B hepatoma cells.

artículo científico publicado en 2000

Low density lipoprotein receptor-related protein 1 dependent endosomal trapping and recycling of apolipoprotein E.

artículo científico publicado en 2012

Mapping quantitative trait loci associated with barley net blotch resistance

artículo científico publicado en 2007

Methodologies for investigating natural medicines for the treatment of nonalcoholic fatty liver disease (NAFLD).

artículo científico publicado en 2012

Molecular mechanisms involved in Ras inactivation: the annexin A6-p120GAP complex.

artículo científico publicado en 2006

Oncogenic Ras modulates p38 MAPK-mediated inflammatory cytokine production in glioblastoma cells

artículo científico publicado en 2016

Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton.

artículo científico publicado en 2009

Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease ⬇️

artículo científico publicado en 2020

Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin

scientific journal article

Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control.

artículo científico publicado en 2014

Ras/mitogen-activated protein kinase (MAPK) signaling modulates protein stability and cell surface expression of scavenger receptor SR-BI.

artículo científico publicado en 2011

Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo.

artículo científico publicado en 2001

Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization.

artículo científico publicado en 2003

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes.

artículo científico publicado en 2015

Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation.

artículo científico publicado en 2017

Signal transduction pathways provide opportunities to enhance HDL and apoAI-dependent reverse cholesterol transport

scientific article published on February 2012

The -6.1-kilobase chicken lysozyme enhancer is a multifactorial complex containing several cell-type-specific elements.

artículo científico publicado en 1992

The cross-talk of LDL-cholesterol with cell motility: insights from the Niemann Pick Type C1 mutation and altered integrin trafficking.

artículo científico publicado en 2015

The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1β-driven IL-6 secretion in glioblastoma cells.

artículo científico publicado en 2014

Triton X-100 promotes a cholesterol-dependent condensation of the plasma membrane.

artículo científico publicado en 2009

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells.

artículo científico publicado en 2012

Lista de obras de Thomas Grewal

Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet

Annexin A6 - a multifunctional scaffold in cell motility

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.

Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells

Annexin A6 in the liver: From the endocytic compartment to cellular physiology

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation ⬇️

Annexin A6 is an organizer of membrane microdomains to regulate receptor localization and signalling

Annexin A6 is highly abundant in monocytes of obese and type 2 diabetic individuals and is downregulated by adiponectin in vitro

Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

Annexin A6 protein is downregulated in human hepatocellular carcinoma.

Annexin A6 regulates adipocyte lipid storage and adiponectin release

Annexin A6 regulates interleukin-2-mediated T-cell proliferation

Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity

Annexin A6-Linking Ca(2+) signaling with cholesterol transport.

Annexin A6-balanced late endosomal cholesterol controls influenza A replication and propagation

Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex

Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi

Annexin A6-regulator of the EGFR/Ras signalling pathway and cholesterol homeostasis

Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment

Annexins - insights from knockout mice.

Annexins - scaffolds modulating PKC localization and signaling

Annexins and endosomal signaling

Annexins in cell migration and adhesion.

Annexins--modulators of EGF receptor signalling and trafficking

Annexins-Coordinators of Cholesterol Homeostasis in Endocytic Pathways.

Annexins: Ca2+ Effectors Determining Membrane Trafficking in the Late Endocytic Compartment.

Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics

Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes

Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis

Casein Kinase 2 Is a Novel Regulator of the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) Trafficking

Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux

Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.

Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function.

Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes

Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes

Desialylated LDL uptake in human and mouse macrophages can be mediated by a lectin receptor

Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP).

Differential Regulation of RasGAPs in Cancer.

Differential involvement of H- and K-Ras in Raf-1 activation determines the role of calmodulin in MAPK signaling.

Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling

Diverse Roles of Annexin A6 in Triple-Negative Breast Cancer Diagnosis, Prognosis and EGFR-Targeted Therapies

Editorial [ Hot Topic:New Methodology and Approaches to Intracellular Lipid Transport in Atherosclerosis and Cardiovascular Disease (Guest Editors: Basil D. Roufogalis and Thomas Grewal)]

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.

Expression of γ-IFN responsive genes in scavenger receptor over-expressing monocytes is associated with xanthomatosis ⬇️

Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations

Functional implications of plasma membrane condensation for T cell activation

GTPases Rac1 and Ras Signaling from Endosomes

Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate-induced apoptosis

High density lipoprotein-induced signaling of the MAPK pathway involves scavenger receptor type BI-mediated activation of Ras.

Highlight: annexins in health and disease

Hydrophobic and basic domains target proteins to lipid droplets

Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets

Identification of a gamma-interferon-responsive element in the promoter of the human macrophage scavenger receptor A gene.

Identification of dual PPARα/γ agonists and their effects on lipid metabolism.

Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene

Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.

Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells.

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

Interleukins in glioblastoma pathophysiology: implications for therapy.

Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

Late endocytic compartments are major sites of annexin VI localization in NRK fibroblasts and polarized WIF-B hepatoma cells.

Low density lipoprotein receptor-related protein 1 dependent endosomal trapping and recycling of apolipoprotein E.

Mapping quantitative trait loci associated with barley net blotch resistance

Methodologies for investigating natural medicines for the treatment of nonalcoholic fatty liver disease (NAFLD).

Molecular mechanisms involved in Ras inactivation: the annexin A6-p120GAP complex.

Oncogenic Ras modulates p38 MAPK-mediated inflammatory cytokine production in glioblastoma cells

Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton.

Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease ⬇️

Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin

Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control.

Ras/mitogen-activated protein kinase (MAPK) signaling modulates protein stability and cell surface expression of scavenger receptor SR-BI.

Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo.

Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization.

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes.