Lista de obras -

"Cushing's disease of the omentum"--fact or fiction?

artículo científico publicado en 2004

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol

artículo científico publicado en 2002

11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target.

artículo científico publicado en 2005

11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes

artículo científico publicado en 2010

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle ⬇️

artículo científico publicado en 2009

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

artículo científico publicado en 2004

11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice ⬇️

artículo científico publicado en 2017

11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess

artículo científico publicado en 2014

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects

artículo científico

11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial

artículo científico publicado en 2020

11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension

artículo científico publicado en 2020

5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes

artículo científico publicado en 2015

A comparative quality assessment of evidence-based clinical guidelines in endocrinology

artículo científico

A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. ⬇️

artículo científico publicado en 2008

A potential role for hepcidin in obesity-driven colorectal tumourigenesis

artículo científico publicado en 2017

A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease ⬇️

artículo científico publicado en 2012

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

artículo científico publicado en 2019

AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome.

artículo científico publicado en 2017

AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease

scientific article published on 19 July 2019

AKR1D1 knockout mice develop a sex-dependent metabolic phenotype

artículo científico publicado en 2022

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

artículo científico publicado en 2019

Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis

artículo científico publicado en 2014

Absence of Cushingoid phenotype in a patient with Cushing's disease due to defective cortisone to cortisol conversion

artículo científico publicado en 2002

Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary steroid metabolome

scientific article published on 16 April 2020

Acute Hypercortisolemia Exerts Depot-Specific Effects on Abdominal and Femoral Adipose Tissue Function

artículo científico publicado en 2017

Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months

artículo científico publicado en 2009

Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol ⬇️

artículo científico publicado en 2015

Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome.

artículo científico publicado en 2016

Altered cortisol metabolism in individuals with HNF1A-MODY

scientific article published on 12 May 2020

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.

artículo científico publicado en 2004

Association between hypercortisolaemia and adipose tissue blood flow in vivo

artículo científico publicado en 2015

Baseline morning cortisol level as a predictor of pituitary-adrenal reserve: a comparison across three assays

artículo científico publicado en 2016

Care standards for non-alcoholic fatty liver disease in the United Kingdom 2016: a cross-sectional survey

artículo científico publicado en 2017

Central hypoadrenalism.

artículo científico publicado en 2014

Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?

artículo científico publicado en 2010

Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat. ⬇️

artículo científico publicado en 2007

Corticosteroids, 11beta-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus.

artículo científico publicado en 2007

Cortisol metabolism, postnatal depression and weight changes in the first 12 months postpartum.

artículo científico publicado en 2016

Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity

artículo científico publicado en 2002

Current therapeutic strategies in non-alcoholic fatty liver disease.

artículo científico publicado en 2011

Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake ⬇️

artículo científico publicado en 2013

Depot-specific prostaglandin synthesis in human adipose tissue: a novel possible mechanism of adipogenesis

artículo científico publicado en 2006

Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle

artículo científico publicado en 2014

Diagnosis and management of adrenal insufficiency

artículo científico

Differential adipose tissue gene expression profiles in abacavir treated patients that may contribute to the understanding of cardiovascular risk: a microarray study

artículo científico publicado en 2015

Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis ⬇️

artículo científico publicado en 2015

Diminished 11β-hydroxysteroid dehydrogenase type 2 activity is associated with decreased weight and weight gain across the first year of life

artículo científico publicado en 2014

Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man

artículo científico publicado en 2015

Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond.

artículo científico publicado en 2016

Early occurrence of new-onset diabetes after transplantation is related to type of liver graft and warm ischaemic injury.

artículo científico publicado en 2014

Editorial: can urine-based metabolomics improve diagnosis of advanced fibrosis in NAFLD? Authors' reply

scientific article published on 01 June 2020

Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome.

artículo científico publicado en 2015

Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence

artículo científico publicado en 2012

Effects of the 5-HT2C receptor agonist meta-chlorophenylpiperazine on appetite, food intake and emotional processing in healthy volunteers

artículo científico publicado en 2014

Electron interactions and transport between coupled quantum Hall edge states

scientific article published on 03 March 2005

Elevated cerebrospinal fluid (CSF) leptin in idiopathic intracranial hypertension (IIH): evidence for hypothalamic leptin resistance?

artículo científico publicado en 2008

Evaluating the Fat Distribution in Idiopathic Intracranial Hypertension Using Dual-Energy X-ray Absorptiometry Scanning.

artículo científico publicado en 2017

Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones

scientific article published on 13 December 2011

Extensive weight loss can reduce immune age by altering IgG N-glycosylation

artículo científico publicado en 2020

Gender-Specific Differences in Skeletal Muscle 11β-HSD1 Expression Across Healthy Aging

artículo científico publicado en 2015

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis.

artículo científico publicado en 2015

Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue

artículo científico publicado en 2007

Glucocorticoids and non-alcoholic fatty liver disease.

artículo científico

Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo

artículo científico publicado en 2013

Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo

artículo científico publicado en 2020

Guidelines for liver transplantation for patients with non-alcoholic steatohepatitis

scientific article published on 10 January 2012

Hepatitis C virus infection is associated with hepatic and adipose tissue insulin resistance that improves after viral cure

scientific article published on 17 January 2019

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2005

Hormonal regulation of lipogenesis

artículo científico publicado en 2013

Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione

artículo científico publicado en 2014

IGFALS gene dosage effects on serum IGF-I and glucose metabolism, body composition, bone growth in length and width, and the pharmacokinetics of recombinant human IGF-I administration

artículo científico publicado en 2014

Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity ⬇️

artículo científico publicado en 2008

Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome

artículo científico publicado en 2009

Increased central adiposity and decreased subcutaneous adipose tissue 11β-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance-A longitudinal cohort study

artículo científico publicado en 2019

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.

artículo científico publicado en 2007

Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue

artículo científico publicado en 2008

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2012

Learning pharmacokinetic models for in vivo glucocorticoid activation

Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial

artículo científico publicado en 2013

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

artículo científico publicado en 2015

Liver biochemical abnormalities in Turner syndrome: A comprehensive characterization of an adult population

scientific article published on 19 August 2018

Longitudinal changes in glucocorticoid metabolism are associated with later development of adverse metabolic phenotype

artículo científico publicado en 2014

Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice

artículo científico publicado en 2013

Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study ⬇️

artículo científico publicado en 2010

Low-dose growth hormone inhibits 11 beta-hydroxysteroid dehydrogenase type 1 but has no effect upon fat mass in patients with simple obesity

artículo científico publicado en 2003

Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease ⬇️

artículo científico publicado en 2016

Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome

artículo científico publicado en 2005

Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement

scientific article published on 16 November 2012

Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.

artículo científico publicado en 2017

Modulation of glucocorticoid action and the treatment of type-2 diabetes

artículo científico publicado en 2007

Mortality in patients with pituitary disease

artículo científico publicado en 2010

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency

artículo científico publicado en 2003

Non-alcoholic fatty liver disease and diabetes

artículo científico publicado en 2016

Nonalcoholic Fatty Liver Disease in Adults: Current Concepts in Etiology, Outcomes, and Management

artículo científico publicado en 2020

Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency

artículo científico publicado en 2009

Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis?

scientific article published on 21 December 2018

Optimizing human hepatocyte models for metabolic phenotype and function: effects of treatment with dimethyl sulfoxide (DMSO).

artículo científico publicado en 2016

Orlistat for overweight subjects with nonalcoholic steatohepatitis.

artículo científico publicado en 2009

PYY plays a key role in the resolution of diabetes following bariatric surgery in humans

artículo científico publicado en 2019

Pathogenesis of non-alcoholic fatty liver disease.

artículo científico publicado en 2009

Peri-operative corticosteroid supplementation for patients on therapeutic glucocorticoids: a national survey

scientific article published on 25 June 2020

Plasma Renin Measurements are Unrelated to Mineralocorticoid Replacement Dose in Patients With Primary Adrenal Insufficiency

artículo científico publicado en 2020

Prevalence and severity of non-alcoholic fatty liver disease are underestimated in clinical practice: impact of a dedicated screening approach at a large university teaching hospital.

artículo científico publicado en 2017

Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.

artículo científico publicado en 2007

Reduced glucocorticoid production rate, decreased 5alpha-reductase activity, and adipose tissue insulin sensitization after weight loss

artículo científico publicado en 2008

Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle

artículo científico publicado en 2013

Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue ⬇️

artículo científico publicado en 2011

Regulation--the real threat to clinical research.

artículo científico publicado en 2008

Response to the Letter: "Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man"

scientific article published on 01 April 2016

SFRP2 Is Associated with Increased Adiposity and VEGF Expression ⬇️

artículo científico publicado en 2016

Safety and efficacy of liraglutide in patients with type 2 diabetes and elevated liver enzymes: individual patient data meta-analysis of the LEAD program.

artículo científico publicado en 2012

Selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome: is the target liver, fat, or both? ⬇️

artículo científico publicado en 2009

Severe asymptomatic non-alcoholic fatty liver disease in routine diabetes care; a multi-disciplinary team approach to diagnosis and management

scientific article published on 15 October 2013

Sex Differences in Hepatic Lipogenesis with Acute Fructose Feeding

Short- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue. ⬇️

artículo científico publicado en 2011

Special issue on Steroids in Obesity and Diabetes ⬇️

artículo científico publicado el 1 de octubre de 2010

Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency

artículo científico publicado en 2008

Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism

artículo científico publicado en 2017

The 5-HT2C receptor agonist meta-chlorophenylpiperazine (mCPP) reduces palatable food consumption and BOLD fMRI responses to food images in healthy female volunteers

artículo científico publicado en 2017

The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1

artículo científico publicado en 2020

The Dehydrogenase Hypothesis

artículo científico

The Endocrine and Metabolic Characteristics of a large Bardet-Biedl syndrome clinic population

artículo científico publicado en 2018

The Short Synacthen (Corticotropin) Test Can Be Used to Predict Recovery of Hypothalamo-Pituitary-Adrenal Axis Function

artículo científico publicado en 2018

The long-term predictive accuracy of the short synacthen (corticotropin) stimulation test for assessment of the hypothalamic-pituitary-adrenal axis

artículo científico publicado en 2005

The role of 11 beta-hydroxysteroid dehydrogenase in central obesity and osteoporosis

artículo científico publicado en 2000

The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy

artículo científico publicado en 2009

Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT).

artículo científico

Treating hypertension in diabetic nephropathy

artículo científico publicado en 2003

Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial

artículo científico publicado en 2018

Understanding androgen action in adipose tissue

artículo científico publicado en 2014

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis

artículo científico publicado en 2014

Very low calorie diets are associated with transient ventricular impairment before reversal of diastolic dysfunction in obesity

scientific article published on 21 November 2018

Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue

artículo científico publicado en 2004

Lista de obras de

"Cushing's disease of the omentum"--fact or fiction?

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol

11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target.

11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle ⬇️

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice ⬇️

11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects

11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial

11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension

5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes

A comparative quality assessment of evidence-based clinical guidelines in endocrinology

A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. ⬇️

A potential role for hepcidin in obesity-driven colorectal tumourigenesis

A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease ⬇️

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome.

AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease

AKR1D1 knockout mice develop a sex-dependent metabolic phenotype

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis

Absence of Cushingoid phenotype in a patient with Cushing's disease due to defective cortisone to cortisol conversion

Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary steroid metabolome

Acute Hypercortisolemia Exerts Depot-Specific Effects on Abdominal and Femoral Adipose Tissue Function

Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months

Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol ⬇️

Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome.

Altered cortisol metabolism in individuals with HNF1A-MODY

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.

Association between hypercortisolaemia and adipose tissue blood flow in vivo

Baseline morning cortisol level as a predictor of pituitary-adrenal reserve: a comparison across three assays

Care standards for non-alcoholic fatty liver disease in the United Kingdom 2016: a cross-sectional survey

Central hypoadrenalism.

Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?

Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat. ⬇️

Corticosteroids, 11beta-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus.

Cortisol metabolism, postnatal depression and weight changes in the first 12 months postpartum.

Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity

Current therapeutic strategies in non-alcoholic fatty liver disease.

Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake ⬇️

Depot-specific prostaglandin synthesis in human adipose tissue: a novel possible mechanism of adipogenesis

Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle

Diagnosis and management of adrenal insufficiency

Differential adipose tissue gene expression profiles in abacavir treated patients that may contribute to the understanding of cardiovascular risk: a microarray study

Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis ⬇️

Diminished 11β-hydroxysteroid dehydrogenase type 2 activity is associated with decreased weight and weight gain across the first year of life

Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man

Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond.

Early occurrence of new-onset diabetes after transplantation is related to type of liver graft and warm ischaemic injury.

Editorial: can urine-based metabolomics improve diagnosis of advanced fibrosis in NAFLD? Authors' reply

Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome.

Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence

Effects of the 5-HT2C receptor agonist meta-chlorophenylpiperazine on appetite, food intake and emotional processing in healthy volunteers

Electron interactions and transport between coupled quantum Hall edge states

Elevated cerebrospinal fluid (CSF) leptin in idiopathic intracranial hypertension (IIH): evidence for hypothalamic leptin resistance?

Evaluating the Fat Distribution in Idiopathic Intracranial Hypertension Using Dual-Energy X-ray Absorptiometry Scanning.

Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones

Extensive weight loss can reduce immune age by altering IgG N-glycosylation

Gender-Specific Differences in Skeletal Muscle 11β-HSD1 Expression Across Healthy Aging

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis.

Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue

Glucocorticoids and non-alcoholic fatty liver disease.

Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo

Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo

Guidelines for liver transplantation for patients with non-alcoholic steatohepatitis

Hepatitis C virus infection is associated with hepatic and adipose tissue insulin resistance that improves after viral cure

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.

Hormonal regulation of lipogenesis

Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione

IGFALS gene dosage effects on serum IGF-I and glucose metabolism, body composition, bone growth in length and width, and the pharmacokinetics of recombinant human IGF-I administration

Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity ⬇️

Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome

Increased central adiposity and decreased subcutaneous adipose tissue 11β-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance-A longitudinal cohort study

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.

Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.

Learning pharmacokinetic models for in vivo glucocorticoid activation

Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial