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116 Strategies and mechanisms for vaccine induction of mucosal T cell immunity.

artículo científico publicado en 2014

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

artículo científico publicado en 2016

A CTL epitope on the circumsporozoite protein of P. yoelii

artículo científico publicado en 1990

A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei ⬇️

artículo científico publicado el 15 de septiembre de 1992

A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients

artículo científico publicado en 2011

A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL

artículo científico publicado en 1999

A mutant p53 tumor suppressor protein is a target for peptide-induced CD8+ cytotoxic T-cells ⬇️

artículo científico publicado el 15 de julio de 1993

A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance

artículo científico publicado en 2005

A novel combination immunotherapy for cancer by IL-13Rα2-targeted DNA vaccine and immunotoxin in murine tumor models

artículo científico publicado en 2011

A novel functional CTL avidity/activity compartmentalization to the site of mucosal immunization contributes to protection of macaques against simian/human immunodeficiency viral depletion of mucosal CD4+ T cells

artículo científico publicado en 2007

A novel immunoregulatory axis of NKT cell subsets regulating tumor immunity

scientific article published on 28 March 2008

A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic renal cell carcinoma

artículo científico publicado en 2010

A prime/boost vaccine regimen alters the rectal microbiome and impacts immune responses and viremia control post-SIV infection in male and female rhesus macaques

scientific article published on 23 September 2020

A push-pull approach to maximize vaccine efficacy: abrogating suppression with an IL-13 inhibitor while augmenting help with granulocyte/macrophage colony-stimulating factor and CD40L

artículo científico publicado en 2002

A push-pull vaccine strategy using Toll-like receptor ligands, IL-15, and blockade of negative regulation to improve the quality and quantity of T cell immune responses

artículo científico publicado en 2011

Adoptive transfer of CD8+ T cells from immune animals does not transfer immunity to blood stage Plasmodium yoelii malaria

artículo científico publicado en 1990

Altered Lipid Tumor Environment and Its Potential Effects on NKT Cell Function in Tumor Immunity

scientific article published on 18 September 2019

An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL.

artículo científico publicado en 2001

An approach to development of specific T-lymphocyte lines by use of preprocessed antigens in Plasmodium vinckei vinckei murine malaria

artículo científico publicado en 1993

An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans.

artículo científico publicado en 1994

An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself

artículo científico publicado en 1990

Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins: Paucity of clones responsive to intact parasites

artículo científico publicado en 1994

Analysis of peptide residues interacting with MHC molecule or T cell receptor. Can a peptide bind in more than one way to the same MHC molecule?

artículo científico publicado en 1990

Analysis of the mechanism for extracellular processing in the presentation of human immunodeficiency virus-1 envelope protein-derived peptide to epitope-specific cytotoxic T lymphocytes

artículo científico publicado en 2000

Antibodies directed against the MHC-I molecule H-2Dd complexed with an antigenic peptide: similarities to a T cell receptor with the same specificity

artículo científico publicado en 2000

Antibody conjugates mimic specific B cell presentation of antigen: relationship between T and B cell specificity

artículo científico publicado en 1987

Antigen conformation determines processing requirements for T-cell activation ⬇️

artículo científico publicado el 1 de noviembre de 1984

Antigen processing for presentation to T lymphocytes: function, mechanisms, and implications for the T-cell repertoire

artículo científico publicado en 1988

Antigen-specific murine T cell clones produce soluble interleukin 2 receptor on stimulation with specific antigens.

artículo científico publicado en 1986

Antigenic peptide interaction with MHC molecules: implications for the design of artificial vaccines.

artículo científico publicado en 1991

Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humans

artículo científico publicado en 1988

Antigenic structures recognized by T cells: towards the rational design of an AIDS vaccine

artículo científico publicado en 1988

Antigenicity of fusion proteins from sarcoma-associated chromosomal translocations

artículo científico publicado en 2001

Approaches and issues in the development of vaccines against HIV.

scientific article published on January 1991

Approaches to improve engineered vaccines for human immunodeficiency virus and other viruses that cause chronic infections

artículo científico publicado en 1999

Assessment of the relative therapeutic effects of vaccines on virus load and immune responses in small groups at several time points: efficacy of mucosal and subcutaneous polypeptide vaccines in rhesus macaques exposed to SHIV.

artículo científico publicado en 2004

Avidity of CD8 T cells sharpens immunodominance

artículo científico publicado en 2007

Balance is a key for happiness

artículo científico publicado en 2013

Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells

artículo científico publicado en 2010

Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy.

artículo científico publicado en 2017

Broad recognition of cytotoxic T cell epitopes from the HIV-1 envelope protein with multiple class I histocompatibility molecules ⬇️

artículo científico publicado el 15 de marzo de 1992

CD1d-restricted natural killer T cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta

artículo científico publicado en 2006

CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapy

artículo científico publicado en 2014

CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.

artículo científico publicado en 1995

Cancer vaccine strategies: translation from mice to human clinical trials.

artículo científico publicado en 2017

Cancer vaccines: 21st century approaches to harnessing an ancient modality to fight cancer.

artículo científico publicado en 2013

Cancer vaccines: translation from mice to human clinical trials

artículo científico publicado en 2018

Candidate HIV type 1 multideterminant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization

artículo científico publicado en 1996

Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1.

artículo científico publicado en 1992

Characterization of a novel human tumor antigen interleukin-13 receptor alpha2 chain.

artículo científico publicado en 2006

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

artículo científico publicado en 2003

Combined prophylactic and therapeutic cancer vaccine: enhancing CTL responses to HPV16 E2 using a chimeric VLP in HLA-A2 mice

scientific article published on 01 June 2006

Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promoting Anticancer Immunity

artículo científico publicado en 2017

Combining anti-CTLA4 with RG7787, an immunotoxin targeting mesothelin, promotes tumor eradication.

artículo científico publicado en 2015

Comparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaques

artículo científico publicado en 2014

Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1[19]) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with a

artículo científico publicado en 1997

Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations

scientific article published on 01 June 1993

Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types

artículo científico publicado en 1991

Construction of synthetic immunogen: use of new T-helper epitope on malaria circumsporozoite protein

artículo científico publicado en 1987

Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis

artículo científico publicado en 2007

Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008).

artículo científico

Cytokine, Chemokine, and Costimulatory Molecule Modulation to Enhance Efficacy of HIV Vaccines ⬇️

artículo científico publicado el 1 de mayo de 2003

Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes

scientific article published on 01 April 1997

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes

artículo científico publicado en 1990

Cytotoxic T cells specific for the circumsporozoite protein of plasmodium falciparum

artículo científico publicado en 1988

Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes

artículo científico publicado en 1997

DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses

artículo científico publicado en 2002

Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop

scientific article published on 01 April 1997

Delicate balance among three types of T cells in concurrent regulation of tumor immunity

artículo científico publicado en 2013

Demonstration of human T lymphotropic virus type I (HTLV-I)-specific T cell responses from seronegative and polymerase chain reaction-negative persons exposed to HTLV-I.

artículo científico publicado en 1994

Dendritic cell-induced activation of adaptive and innate antitumor immunity

artículo científico publicado en 2003

Development of a malaria T-cell vaccine for blood stage immunity

artículo científico publicado en 1992

Development of artificial vaccines against HIV using defined epitopes ⬇️

artículo científico publicado el 1 de julio de 1991

Development of smallpox vaccine candidates with integrated interleukin-15 that demonstrate superior immunogenicity, efficacy, and safety in mice

artículo científico publicado en 2007

Differential Regulation of T-cell mediated anti-tumor memory and cross-protection against the same tumor in lungs versus skin.

artículo científico publicado en 2018

Differential T cell homing to colon vs. small intestine is imprinted by local CD11c+ APCs that determine homing receptors

artículo científico publicado en 2017

Diversity Outbred Mice Reveal the Quantitative Trait Locus and Regulatory Cells of HER2 Immunity

scientific article published on 12 August 2020

Does Freund's adjuvant denature protein antigens? EPR studies of emulsified hemoglobin ⬇️

artículo científico publicado el 1 de febrero de 1976

Early SIV Dissemination After Intrarectal SIVmac251 Challenge Was Associated With Proliferating Virus-Susceptible Cells in the Colorectum

artículo científico publicado en 2015

Early role of CD4+ Th1 cells and antibodies in HER-2 adenovirus vaccine protection against autochthonous mammary carcinomas.

artículo científico publicado en 2005

Effect of TLR agonists on the differentiation and function of human monocytic myeloid-derived suppressor cells

artículo científico publicado en 2015

Effect of Zidovudine Postexposure Prophylaxis on the Development of HIV-Specific Cytotoxic T-Lymphocyte Responses in HIV-Exposed Healthcare Workers

article

Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.

artículo científico publicado en 2018

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection

artículo científico publicado en 2002

Effects on tumor immunity of anti-TGF-beta with different isoform specificities.

artículo científico publicado en 2014

Enhanced cell surface expression, immunogenicity and genetic stability resulting from a spontaneous truncation of HIV Env expressed by a recombinant MVA.

artículo científico publicado en 2007

Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence ⬇️

artículo científico publicado el 30 de septiembre de 1997

Enhancement of CD8+ T cell immunity in the lung by CpG oligodeoxynucleotides increases protective efficacy of a modified vaccinia Ankara vaccine against lethal poxvirus infection even in a CD4-deficient host

artículo científico publicado en 2006

Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin

artículo científico publicado en 1986

Episomal expression of truncated listeriolysin O in LmddA-LLO-E7 vaccine enhances antitumor efficacy by preferentially inducing expansions of CD4+FoxP3- and CD8+ T cells

artículo científico publicado en 2014

Epitope Selection and Design of Synthetic Vaccines Molecular Approaches to Enhancing Immunogenicity and Cross‐Reactivity of Engineered Vaccines ⬇️

artículo científico publicado el 12 de agosto de 1993

Epitope enhancement of a CD4 HIV epitope toward the development of the next generation HIV vaccine

artículo científico publicado en 2006

Epitope-enhanced conserved HIV-1 peptide protects HLA-A2-transgenic mice against virus expressing HIV-1 antigen

artículo científico publicado en 2003

Evidence for selection against human lung cancers bearing p53 missense mutations which occur within the HLA A*0201 peptide consensus motif

scientific article published on 01 March 1994

Evidence implicating MHC genes in the immunological nonresponsiveness to the plasmodium falciparum CS protein

artículo científico publicado en 1990

Excess β2 microglobulin promoting functional peptide association with purified soluble class I MHC molecules

artículo científico publicado en 1991

Exposure to human immunodeficiency virus (HIV) type I indicated by HIV-specific T helper cell responses before detection of infection by polymerase chain reaction and serum antibodies [corrected]

artículo científico publicado en 1991

Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients

artículo científico publicado en 2017

Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus

artículo científico publicado en 2005

Fc epsilon receptor-positive cells are a major source of antigen-induced interleukin-4 in spleens of mice infected with Schistosoma mansoni

scientific article published on 01 August 1993

Features of T-cell recognition and antigen structure useful in the design of vaccines to elicit T-cell immunity

artículo científico

Fine specificity of T cell recognition of the same peptide in association with different I-A molecules

scientific article published on 01 August 1989

Fixation and cryopreservation of whole blood and isolated mononuclear cells: Influence of different procedures on lymphocyte subset analysis by flow cytometry

artículo científico publicado en 2005

From genome to vaccine—new immunoinformatics tools for vaccine design

article by Anne Searls De Groot & Jay A Berzofsky published December 2004 in Methods

Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization

artículo científico publicado en 2008

Genetic control of immunity to Plasmodium yoelii sporozoites

artículo científico publicado en 1989

Genetic control of the T lymphocyte proliferative response to staphylococcal nuclease: evidence for multiple MHC-linked Ir gene control ⬇️

artículo científico publicado el 1 de mayo de 1978

Genetic control of the immune response in mice to a Plasmodium falciparum sporozoite vaccine. Widespread nonresponsiveness to single malaria T epitope in highly repetitive vaccine

artículo científico publicado en 1986

Genetic control of the immune response to myoglobin. III. Determinant-specific, two Ir gene phenotype is regulated by the genotype of reconstituting Kupffer cells ⬇️

artículo científico publicado el 1 de febrero de 1980

Genetic control of the immune response to myoglobin. V. Antibody production in vitro is macrophage and T cell-dependent and is under control of two determinant-specific Ir genes ⬇️

artículo científico publicado el 1 de junio de 1982

Genetic control of the immune response to myoglobins. IV. Inhibition of determinant-specific Ir gene-controlled antigen presentation and induction of suppression by pretreatment of presenting cells with anti-Ia antibodies ⬇️

artículo científico publicado el 1 de mayo de 1981

Genetic control of the immune response to myoglobins. VI. Distinct Ir genes for different myoglobins: complementing genes in I-A and H-2D for equine myoglobin

artículo científico publicado en 1982

Genetic control of the immune response to staphylococcal nuclease. III. Time-course and correlation between the response to native nuclease and the response to its polypeptide fragments ⬇️

artículo científico publicado el 1 de enero de 1977

Genetic control of the immune response to staphylococcal nuclease. IV. H-2-linked control of the relative proportions of antibodies produced to different determinants of native nuclease ⬇️

artículo científico publicado el 1 de enero de 1977

Genetic control of the immune response to staphylococcal nuclease. VII. Role of non-H-2-linked genes in the control of the anti-nuclease antibody response ⬇️

artículo científico publicado el 1 de febrero de 1978

Genetic regulation of protective immune response in congenic strains of mice vaccinated with a subunit malaria vaccine.

artículo científico publicado en 1996

Genetic restriction of protective immunity to Plasmodium yoelii sporozoites.

artículo científico publicado en 1990

Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells

scientific article published in Science

HPV-16 L1 VLP vaccine elicits a broad-spectrum of cytokine responses in whole blood

artículo científico publicado en 2005

Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance

artículo científico publicado en 1993

Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs.

artículo científico publicado en 1994

Hemagglutinin protein is a primary target of the measles virus-specific HLA-A2-restricted CD8+ T cell response during measles and after vaccination

artículo científico publicado en 2007

High Sensitivity Protein Gel Electrophoresis Label Compatible with Mass-Spectrometry

scientific article published on 31 October 2020

High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer.

artículo científico publicado en 2019

Human CTLs to wild-type and enhanced epitopes of a novel prostate and breast tumor-associated protein, TARP, lyse human breast cancer cells

artículo científico publicado en 2004

Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein

artículo científico publicado en 1989

Human T clones reactive to the sexual stages of plasmodium falciparum malaria. high frequency of gamete-reactive T cells in peripheral blood from nonexposed donors

artículo científico publicado en 1987

Human T-cell recognition of the circumsporozoite protein of plasmodium falciparum: Immunodominant T-cell domains map to the polymorphic regions of the molecule

artículo científico publicado en 1988

Human and murine CD4 T cell epitopes map to the same region of the malaria circumsporozoite protein: Limited immunogenicity of sporozoites and circumsporozoite protein

artículo científico publicado en 1988

Human immunodeficiency virus type 1 (HIV-1)-seronegative injection drug users at risk for HIV exposure have antibodies to HLA class I antigens and T cells specific for HIV envelope

artículo científico publicado en 1996

Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses

artículo científico publicado en 2014

Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins

artículo científico publicado en 1987

IL 1 induction by murine T cell clones: detection of an IL 1-inducing lymphokine

scientific article published on 01 April 1987

IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

artículo científico publicado en 2013

IL-1 is an autocrine growth factor for T cell clones

scientific article published on 01 December 1988

IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

artículo científico publicado en 2008

IL-15 ex vivo overcomes CD4+ T cell deficiency for the induction of human antigen-specific CD8+ T cell responses

artículo científico publicado en 2011

IL-15 expands unconventional CD8alphaalphaNK1.1+ T cells but not Valpha14Jalpha18+ NKT cells

artículo científico publicado en 2008

IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

scholarly article

IL13Rα2 expression identifies tissue-resident IL-22 producing PLZF+ innate T cells in the human liver.

artículo científico publicado en 2018

INT230-6 shows strong synergy with anti-PD-1 and can induce high complete response rates with T cell memory response in a colon cancer mouse model.

artículo científico publicado en 2015

Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE.

artículo científico publicado en 2013

Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors

artículo científico publicado en 2006

Identification of H-2Db-specific CD8+ T-cell epitopes from mouse VEGFR2 that can inhibit angiogenesis and tumor growth

artículo científico publicado en 2006

Identification of T-cell epitopes and use in construction of synthetic vaccines

artículo científico publicado en 1989

Identification of a nonameric H-2Kk-restricted CD8+ cytotoxic T lymphocyte epitope on the Plasmodium falciparum circumsporozoite protein

artículo científico publicado en 1995

Identification of an immunodominant and highly immunopathogenic determinant in the retinal interphotoreceptor retinoid-binding protein (IRBP).

artículo científico publicado en 1989

Identification of distinct predominant epitopes recognized by myoglobin-specific T cells under the control of different Ir genes and characterization of representative T cell clones ⬇️

artículo científico publicado el 1 de marzo de 1984

Identification of proteases that process distinct epitopes on the same protein

artículo científico publicado en 1989

Idiotypes of anti-myoglobin antibodies: shared idiotypes among monoclonal antibodies to distinct determinants of sperm whale myoglobin ⬇️

artículo científico publicado el 1 de abril de 1982

Immune activation in cervical neoplasia: cross-sectional association between plasma soluble interleukin 2 receptor levels and disease ⬇️

artículo científico publicado el 1 de octubre de 1997

Immune response gene regulation of immunity to Plasmodium berghei sporozoites and circumsporozoite protein vaccines. Overcoming genetic restriction with whole organism and subunit vaccines.

artículo científico publicado en 1989

Immune targeting of PD-1(hi) expressing cells during and after antiretroviral therapy in SIV-infected rhesus macaques

artículo científico publicado en 2013

Immunization of mice against Plasmodium vinckei with a combination of attenuated Salmonella typhimurium and malarial antigen

artículo científico publicado en 1990

Immunization with mutant p53- and K-ras-derived peptides in cancer patients: immune response and clinical outcome

artículo científico publicado en 2005

Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1.

artículo científico publicado en 1992

Immunization with subunit human immunodeficiency virus vaccine generates stronger T helper cell immunity than natural infection

artículo científico publicado en 1991

Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines

artículo científico publicado en 2004

Immunogenicity and immunopathogenicity of an autoimmune epitope are potentiated by increasing MHC binding through residue substitution

artículo científico publicado en 1997

Immunologically relevant peptide antigen exists on the presenting cell in a manner accessible to macromolecules in solution

artículo científico publicado en 1986

Immunoregulatory T cells in tumor immunity

artículo científico publicado en 2004

Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites

artículo científico publicado en 2001

Immunotherapy biomarkers 2016: overcoming the barriers.

scientific article published on 21 March 2017

Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa

artículo científico publicado en 2005

In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10.

artículo científico publicado en 1996

Inactivation of human immunodeficiency virus (HIV)-1 envelope-specific CD8+ cytotoxic T lymphocytes by free antigenic peptide: a self-veto mechanism?

artículo científico publicado en 1996

Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: association of viral persistence with egg granuloma formation

artículo científico publicado en 1994

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

artículo científico publicado en 1990

Induction of CD8+ cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells

artículo científico publicado en 1993

Induction of broadly cross-reactive cytotoxic T cells recognizing an HIV-1 envelope determinant

artículo científico publicado el 17 de enero de 1992

Induction of cytotoxic T lymphocytes and antitumor immunity with DNA vaccines expressing single T cell epitopes

artículo científico publicado en 1996

Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen

scientific article published on 01 May 1992

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques

article

Influences of antigen processing on the expression of the T cell repertoire. Evidence for MHC-specific hindering structures on the products of processing

artículo científico publicado en 1988

Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy

artículo científico publicado en 2020

Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques

artículo científico publicado en 2010

Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology

article

Interleukin 2 receptor expression in unstimulated murine splenic T cells. Localization to L3T4+ cells and regulation by non-H-2-linked genes

artículo científico publicado en 1986

Interleukin 21 collaborates with interferon-γ for the optimal expression of interferon-stimulated genes and enhances protection against enteric microbial infection

article

Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes

artículo científico publicado en 2015

Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals

artículo científico publicado en 1989

Interplay of cytokines and adjuvants in the regulation of mucosal and systemic HIV-specific CTL.

artículo científico publicado en 2000

Intratumoral therapy with IL13-PE38 results in effective CTL-mediated suppression of IL-13Ralpha2-expressing contralateral tumors

artículo científico publicado en 2006

Intratumorally delivered formulation, INT230-6, containing potent anticancer agents induces protective T cell immunity and memory

artículo científico publicado en 2019

Ir genes of different high responder haplotypes for staphylococcal nuclease are not allelic

scientific article published on 01 December 1981

Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

artículo científico publicado en 2017

Lack of IL-7 and IL-15 signaling affects interferon-γ production by, more than survival of, small intestinal intraepithelial memory CD8+ T cells.

artículo científico publicado en 2011

Lack of the programmed death-1 receptor renders host susceptible to enteric microbial infection through impairing the production of the mucosal natural killer cell effector molecules.

artículo científico publicado en 2015

Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection

artículo científico publicado en 2012

Limited immunological recognition of critical malaria vaccine candidate antigens

artículo científico publicado en 1988

Limiting dilution comparison of the repertoires of high and low responder MHC-restricted T cells

artículo científico publicado en 1988

Liver sulfatide-reactive type II NKT cells recognize endogenous phospholipids

Low Antigen Dose in Adjuvant-Based Vaccination Selectively Induces CD4 T Cells with Enhanced Functional Avidity and Protective Efficacy.

artículo científico publicado en 2017

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

artículo científico publicado en 2005

Mapping the idiotopes of a monoclonal anti-myoglobin antibody with syngeneic monoclonal anti-idiotypic antibodies: detection of a common idiotope

scientific article published on 01 February 1986

Mechanisms of T cell recognition with application to vaccine design ⬇️

artículo científico publicado el 1 de marzo de 1991

Mechanisms of immunodominance in T-cell recognition, with applications to vaccine design

artículo científico publicado en 1988

Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques

artículo científico publicado en 2003

Molecular Structure and Vaccine Design ⬇️

artículo científico publicado el 1 de enero de 1990

Molecular analysis of a heteroclitic T cell response to the immunodominant epitope of sperm whale myoglobin. Implications for peptide partial agonists ⬇️

artículo científico publicado el 1 de noviembre de 1995

Molecular mapping of a histocompatibility-restricted immunodominant T cell epitope with synthetic and natural peptides: implications for T cell antigenic structure

artículo científico publicado en 1986

Molecular studies of antigen processing and presentation to T cells by class II MHC molecules

artículo científico

Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques

article

Mucosal AIDS vaccines: current status and future directions

artículo científico publicado en 2004

Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response

article

Multiple Antigen Peptide Vaccines againstPlasmodium falciparumMalaria ⬇️

artículo científico publicado el 7 de septiembre de 2010

Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides.

artículo científico publicado en 1993

Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells

artículo científico publicado en 2016

Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate

article

Myeloid Cell-Mediated Trained Innate Immunity in Mucosal AIDS Vaccine Development

scientific article published on 28 February 2020

NK and CTL recognition of a single chain H-2Dd molecule: distinct sites of H-2Dd interact with NK and TCR.

artículo científico publicado en 1999

NKT cell networks in the regulation of tumor immunity

artículo científico publicado en 2014

NKT cells in tumor immunity: opposing subsets define a new immunoregulatory axis

artículo científico publicado en 2008

Natural immunosurveillance against spontaneous, autochthonous breast cancers revealed and enhanced by blockade of IL-13-mediated negative regulation.

artículo científico publicado en 2007

Neonatal exposure to immunogenic peptides. Differential susceptibility to tolerance induction of helper T cells and B cells reactive to malarial circumsporozoite peptide epitopes.

artículo científico publicado en 1988

New insights and approaches regarding B- and T-cell epitopes in HIV vaccine design

artículo científico publicado en 1999

Nonhuman primate models for HIV/AIDS vaccine development

artículo científico publicado en 2013

Novel approaches to peptide and engineered protein vaccines for HIV using defined epitopes: advances in 1994-1995.

artículo científico publicado en 1995

Oral vaccines: directed safe passage to the front line of defense

artículo científico publicado en 2013

Overcoming CD4 deficiency to induce long-lived memory CD8+ CTL.

artículo científico publicado en 2006

Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques.

artículo científico publicado en 2017

Parasite polymorphism present within minimal T cell epitopes of Plasmodium falciparum circumsporozoite protein

artículo científico publicado en 1988

Pathogenic roles of CD14, galectin-3, and OX40 during experimental cerebral malaria in mice

artículo científico publicado en 2009

Peptide vaccines against cancer.

artículo científico publicado en 2005

Peptide-induced mRNAs in whole blood ex vivo as a unique assay for peptide-specific T cell immunity

artículo científico publicado en 2013

Peptides containing multideterminant clusters of human immunodeficiency virus envelope induce murine and human T-cell responses in diverse histocompatibility types

article

Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection

artículo científico publicado en 1998

Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma

artículo científico publicado en 2014

Physiology of IgD. VII. Induction of receptors for IgD on cloned T cells by IgD and interleukin 2.

artículo científico publicado en 1987

Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: an inter-institute NIH study

artículo científico publicado en 2002

Plasma from some cancer patients inhibits adenoviral Ad5f35 vector transduction of dendritic cells.

artículo científico publicado en 2018

Plasmid DNA-based immunization for hepatitis C virus structural proteins: immune responses in mice

artículo científico publicado en 1997

Plasmodium falciparum: sporozoite boosting of immunity due to a T-cell epitope on a sporozoite vaccine

artículo científico publicado en 1987

Possible Therapeutic Application of Targeting Type II Natural Killer T Cell-Mediated Suppression of Tumor Immunity.

artículo científico publicado en 2018

Possible therapeutic vaccine strategy against human immunodeficiency virus escape from reverse transcriptase inhibitors studied in HLA-A2 transgenic mice

artículo científico publicado en 2006

Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer

artículo científico publicado en 2014

Prediction of HIV peptide epitopes by a novel algorithm.

artículo científico publicado en 1996

Prediction of immunodominant helper T cell antigenic sites from the primary sequence

artículo científico publicado en 1987

Preferential V beta usage by cytotoxic T cells cross-reactive between two epitopes of HIV-1 gp160 and degenerate in class I MHC restriction ⬇️

artículo científico publicado el 15 de agosto de 1993

Preliminary association of circulating tumor cells (CTCs) pre- and post-AdHER2 dendritic cell vaccination with overall survival in patients with metastatic HER2+ solid tumors

artículo científico publicado en 2015

Production of T-T hybrids from T cell clones. Direct comparison between cloned T cells and T hybridoma cells derived from them

artículo científico publicado en 1988

Progress on new vaccine strategies against chronic viral infections

artículo científico publicado en 2004

Progress on new vaccine strategies for the immunotherapy and prevention of cancer

artículo científico publicado en 2004

Progress toward an artificial vaccine for HIV: identification of helper and cytotoxic T-cell epitopes and methods of immunization

artículo científico publicado el 1 de enero de 1991

Properties of monoclonal antibodies specific for determinants of a protein antigen, myoglobin

scientific article published on 01 December 1980

Prospective Use of High-Refractive Index Materials for Single Molecule Detection in Flow Cytometry

scholarly article by Joshua A Welsh et al published 1 August 2018 in Sensors

Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

artículo científico publicado en 2021

Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses

artículo científico publicado en 2004

Protective immunity provided by HLA-A2 epitopes for fusion and hemagglutinin proteins of measles virus.

artículo científico publicado en 2006

Protein antigenic structures recognized by T cells: potential applications to vaccine design

artículo científico publicado en 1987

Rapid induction of apoptosis in CD8+ HIV-1 envelope-specific murine CTLs by short exposure to antigenic peptide

artículo científico publicado en 2002

Reciprocal cytotoxic T lymphocyte cross-reactivity interactions between two major epitopes within HIV-1 gp160

scientific article published on 01 November 1996

Recognition of peptides that are immunopathogenic but cryptic. Mechanisms that allow lymphocytes sensitized against cryptic peptides to initiate pathogenic autoimmune processes.

artículo científico publicado en 1991

Recombinant human IL-2 overcomes genetic nonresponsiveness to malaria sporozoite peptides. Correlation of effect with biologic activity of IL-2.

artículo científico publicado en 1988

Regulation of tumor immunity: the role of NKT cells

artículo científico publicado en 2008

Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-gamma dependent.

artículo científico publicado en 2002

Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2.

artículo científico publicado en 2008

Role of CD4 T cell helper subsets in immune response and deviation of CD8 T cells in mice

artículo científico publicado en 2017

Role of IL-13 in regulation of anti-tumor immunity and tumor growth ⬇️

artículo científico publicado el 11 de noviembre de 2003

Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection

artículo científico publicado en 1992

Role of alpha3 domain of class I MHC molecules in the activation of high- and low-avidity CD8+ CTLs.

artículo científico publicado en 2007

Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL

artículo científico publicado en 1996

Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus

artículo científico publicado en 1994

Role of intrastructural/intermolecular help in immunization with peptide-phospholipid complexes

scientific article published on 01 July 1991

Selective induction of high avidity CTL by altering the balance of signals from APC.

artículo científico publicado en 2003

Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway.

artículo científico publicado en 2014

Semi-allogeneic cell hybrids stimulate HIV-1 envelope-specific cytotoxic T lymphocytes

artículo científico publicado en 2000

Sequences outside a minimal immunodominant site exert negative effects on recognition by staphylococcal nuclease-specific T cell clones

artículo científico publicado en 1989

Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses

artículo científico publicado en 2003

Strategies for designing and optimizing new generation vaccines

artículo científico publicado en 2001

Strategies for developing and optimizing cancer vaccines

artículo científico publicado en 2019

Strategies to use immune modulators in therapeutic vaccines against cancer

artículo científico publicado en 2012

Structural basis of antigen recognition by T lymphocytes. Implications for vaccines

artículo científico publicado en 1988

Structural features of T-cell recognition: applications to vaccine design

artículo científico

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein

artículo científico publicado en 1989

Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes

artículo científico publicado en 1998

Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody

artículo científico publicado en 2009

Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels

artículo científico publicado en 2006

T cell clones specific for an amphipathic alpha-helical region of sperm whale myoglobin show differing fine specificities for synthetic peptides. A multiview/single structure interpretation of immunodominance

artículo científico publicado en 1986

T cell clones to two major T cell epitopes of myoglobin: effect of I-A/I-E restriction on epitope dominance

artículo científico publicado en 1985

T cell recognition of hypervariable region-1 from hepatitis C virus envelope protein with multiple class II MHC molecules in mice and humans: preferential help for induction of antibodies to the hypervariable region.

artículo científico publicado en 1999

T-cell antigenic sites tend to be amphipathic structures

artículo científico publicado en 1985

TARP vaccination is associated with slowing in PSA velocity and decreasing tumor growth rates in patients with Stage D0 prostate cancer

artículo científico publicado en 2016

TLR agonists and/or IL-15 adjuvanted mucosal SIV vaccine reduced gut CD4⁺ memory T cell loss in SIVmac251-challenged rhesus macaques

artículo científico publicado en 2011

Targeting TARP, a novel breast and prostate tumor-associated antigen, with T cell receptor-like human recombinant antibodies

artículo científico publicado en 2008

The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentation

artículo científico publicado en 2008

The NS2 Protein of Human Respiratory Syncytial Virus Suppresses the Cytotoxic T-Cell Response as a Consequence of Suppressing the Type I Interferon Response.

artículo científico publicado en 2006

The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response ⬇️

artículo científico publicado en 2006

The T cell response to the malaria circumsporozoite protein: an immunological approach to vaccine development

artículo científico publicado en 1988

The antigenic structure of proteins: a reappraisal.

artículo científico publicado en 1984

The combination of GM-CSF and IL-2 as local adjuvant shows synergy in enhancing peptide vaccines and provides long term tumor protection

artículo científico publicado en 2007

The contrasting roles of NKT cells in tumor immunity

artículo científico publicado en 2009

The effect of antigen dose on T cell-targeting vaccine outcome

artículo científico publicado en 2018

The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors

artículo científico publicado en 1977

The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition

artículo científico publicado en 1993

The importance of local mucosal HIV-specific CD8(+) cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administration of IL-12.

artículo científico publicado en 1998

The murine Kupffer cell. I. Characterization of the cell serving accessory function in antigen-specific T cell proliferation ⬇️

artículo científico publicado el 1 de diciembre de 1979

The organization of human leucocyte antigen class I epitopes in HIV genome products: implications for HIV evolution and vaccine design ⬇️

artículo científico publicado el 1 de agosto de 1997

The role of CD4+ T cells in immunity to malaria sporozoites

artículo científico publicado en 1993

Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus

scientific article published on 18 May 2020

Therapy of advanced established murine breast cancer with a recombinant adenoviral ErbB-2/neu vaccine

artículo científico publicado en 2008

Tissue-Specific Roles of NKT Cells in Tumor Immunity

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines

artículo científico publicado en 2008

Topographic antigenic determinants recognized by monoclonal antibodies to sperm whale myoglobin ⬇️

artículo científico publicado el 25 de marzo de 1982

Toward a vaccine for AIDS: the emergence of immunobiology-based vaccine development

artículo científico publicado en 1994

Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells

artículo científico publicado en 2004

Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17

artículo científico publicado en 2008

Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining

artículo científico publicado en 2001

Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences.

artículo científico publicado en 1995

Type II NKT cells differentially regulate CD4 T cell subsets

Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology ⬇️

artículo científico publicado en 2020

Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13.

artículo científico publicado en 2005

Unsung Hero Robert C. Gallo

artículo científico publicado en 2009

Use of Bioinformatics to Predict MHC Ligands and T-Cell Epitopes

article published in 2010

Use of bioinformatics to predict MHC ligands and T-cell epitopes: Application to epitope-driven vaccine design

Use of intrinsic and extrinsic helper epitopes for in vivo induction of anti-hepatitis C virus cytotoxic T lymphocytes (CTL) with CTL epitope peptide vaccines

artículo científico publicado en 1996

Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice

artículo científico publicado en 2010

Vaccination and Autoimmunity

scholarly article published 28 January 2004

Vaccination by genetically modified dendritic cells expressing a truncated neu oncogene prevents development of breast cancer in transgenic mice

artículo científico publicado en 2004

Vaccine-induced myeloid cell population dampens protective immunity to SIV

artículo científico publicado en 2014

Vaginal type-II mucosa is an inductive site for primary CD8⁺ T-cell mucosal immunity.

artículo científico publicado en 2015

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