Lista de obras - Santiago Vazquez - Dominio Público Uruguay

3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.

artículo científico publicado en 2013

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

scientific article published on 22 March 2020

Alternative syntheses of the new D2d symmetric tetramethyl tricyclo- [3.3.0.0(3,7)]octane-1,3,5,7-tetracarboxylate.

artículo científico publicado en 2003

Aniline-based inhibitors of influenza H1N1 virus acting on hemagglutinin-mediated fusion.

artículo científico publicado en 2017

Antibacterial activity of novel benzopolycyclic amines

artículo científico publicado en 2014

Azapropellanes with anti-influenza a virus activity.

artículo científico publicado en 2014

Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction

artículo científico publicado en 2017

Dimerization of pyramidalized 3,4,8,9-tetramethyltetracyclo [4.4.0.0(3,9).0(4,8)]dec-1(6)-ene to a hydrocarbon featuring four cyclohexane rings in boat conformations

artículo científico publicado en 2014

Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease

artículo científico publicado en 2022

Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus

artículo científico publicado en 2014

Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles. ⬇️

artículo científico publicado en 2017

Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors.

artículo científico publicado en 2018

Generation and reactions of two new functionalized tricyclo[3.3.0.0 3,7]oct-1(5)-ene derivatives.

artículo científico publicado en 2005

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

artículo científico publicado en 2021

Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel

artículo científico publicado en 2016

New polycyclic dual inhibitors of the wild type and the V27A mutant M2 channel of the influenza A virus with unexpected binding mode.

artículo científico publicado en 2015

Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold

artículo científico publicado en 2015

Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept

artículo científico publicado en 2018

Novel benzopolycyclic amines with NMDA receptor antagonist activity

scientific article published on 24 March 2014

Palladium-catalyzed cocyclotrimerization of arynes with a pyramidalized alkene

artículo científico publicado en 2018

Pentafluorosulfanyl-containing Triclocarban Analogs with Potent Antimicrobial Activity

artículo científico publicado en 2018

Pharmacological and Electrophysiological Characterization of Novel NMDA Receptor Antagonists

scientific article published on 01 June 2018

Polycyclic N-benzamido imides with potent activity against vaccinia virus.

artículo científico publicado en 2010

Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds.

artículo científico publicado en 2013

Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors

artículo científico publicado en 2015

Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus

artículo científico publicado en 2017

Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy

scientific article published on 01 May 2020

Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds.

artículo científico publicado en 2012

Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines.

artículo científico publicado en 2009

Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities.

artículo científico publicado en 2011

Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists

artículo científico publicado en 2018

Lista de obras de Santiago Vazquez

3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

Alternative syntheses of the new D2d symmetric tetramethyl tricyclo- [3.3.0.0(3,7)]octane-1,3,5,7-tetracarboxylate.

Aniline-based inhibitors of influenza H1N1 virus acting on hemagglutinin-mediated fusion.

Antibacterial activity of novel benzopolycyclic amines

Azapropellanes with anti-influenza a virus activity.

Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction

Dimerization of pyramidalized 3,4,8,9-tetramethyltetracyclo [4.4.0.0(3,9).0(4,8)]dec-1(6)-ene to a hydrocarbon featuring four cyclohexane rings in boat conformations

Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease

Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus

Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles. ⬇️

Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors.

Generation and reactions of two new functionalized tricyclo[3.3.0.0 3,7]oct-1(5)-ene derivatives.

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel

New polycyclic dual inhibitors of the wild type and the V27A mutant M2 channel of the influenza A virus with unexpected binding mode.

Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold

Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept

Novel benzopolycyclic amines with NMDA receptor antagonist activity

Palladium-catalyzed cocyclotrimerization of arynes with a pyramidalized alkene

Pentafluorosulfanyl-containing Triclocarban Analogs with Potent Antimicrobial Activity

Pharmacological and Electrophysiological Characterization of Novel NMDA Receptor Antagonists

Polycyclic N-benzamido imides with potent activity against vaccinia virus.

Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds.

Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors

Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus

Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy

Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds.

Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines.

Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities.

Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists