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Lista de obras de Stephanie Hughes

250. Protection Against Huntington's Diease Progression: AAV-Mediated Delivery of Biotherapeutics

scholarly article by Adrian P. Kells et al published 2006 in Molecular Therapy

451. AAV-BDNF Augments Neurogenesis in Both the Normal Adult Rat Brain and the Quinolinic Acid Lesion Model of Huntington's Disease

scholarly article by Rebecca A. Henry et al published 2006 in Molecular Therapy

A C-terminal peptide from secreted amyloid precursor protein-α enhances long-term potentiation in rats and a transgenic mouse model of Alzheimer's disease

scientific article published on 13 June 2019

A schizophrenia risk factor induces marked anatomical deficits at GABAergic ‐dopaminergic synapses in the rat ventral tegmental area: Essential evidence for new targeted therapies

artículo científico publicado en 2021

AAV-mediated delivery of BDNF augments neurogenesis in the normal and quinolinic acid-lesioned adult rat brain.

artículo científico publicado en 2007

Adult-born dentate granule cell excitability depends on the interaction of neuron age, ontogenetic age and experience

artículo científico publicado en 2018

An altered secretome is an early marker of the pathogenesis of CLN6 Batten disease

artículo científico publicado en 2020

CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain

scientific article published on 20 October 2020

Cellular composition of human glial cultures from adult biopsy brain tissue

article

Characterisation of early changes in ovine CLN5 and CLN6 Batten disease neural cultures for the rapid screening of therapeutics

artículo científico publicado en 2017

Chimeric rabies SADB19-VSVg-pseudotyped lentiviral vectors mediate long-range retrograde transduction from the mouse spinal cord.

artículo científico publicado en 2015

Combined Immunochemistry and Live Imaging of Fluorescent Protein Expressing Neurons in Mouse Brain

article by Ruth M. Empson et al published 2015 in Neuromethods

Creating a neurogenic environment: the role of BDNF and FGF2.

artículo científico publicado en 2007

Diversity of layer 5 projection neurons in the mouse motor cortex.

artículo científico publicado en 2013

Experimental therapies in the neuronal ceroid lipofuscinoses

artículo científico publicado en 2015

Expression of the developmental transcription factor Fezf2 identifies a distinct subpopulation of layer 5 intratelencephalic-projection neurons in mature mouse motor cortex.

artículo científico publicado en 2014

Fezf2 expression in layer 5 projection neurons of mature mouse motor cortex.

artículo científico publicado en 2015

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors

artículo científico publicado en 2002

Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease

artículo científico publicado en 2019

Genetic targeting and chemogenetic inhibition of new born neurons

scientific article published on 07 December 2018

Inhibition of storage pathology in prenatal CLN5-deficient sheep neural cultures by lentiviral gene therapy.

artículo científico publicado en 2013

Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms.

artículo científico

Lentiviral-mediated gene transfer to the sheep brain: implications for gene therapy in Batten disease.

artículo científico publicado en 2011

Lentivirus-Mediated Expression of Human Secreted Amyloid Precursor Protein-Alpha Promotes Long-Term Induction of Neuroprotective Genes and Pathways in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2020

Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease

artículo científico publicado en 2018

Longitudinal In Vivo Monitoring of the CNS Demonstrates the Efficacy of Gene Therapy in a Sheep Model of CLN5 Batten Disease

article

Neural development in human embryonic stem cells-applications of lentiviral vectors.

artículo científico publicado en 2011

Neural progenitor cells derived from the adult rat subventricular zone: characterization and transplantation

scientific article published on 01 January 2007

Neuroproteomic Analysis after SARS-CoV-2 Infection Reveals Overrepresented Neurodegeneration Pathways and Disrupted Metabolic Pathways

artículo científico publicado en 2023

Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer's disease

artículo científico publicado en 2022

Patterned, but not tonic, optogenetic stimulation in motor thalamus improves reaching in acute drug-induced Parkinsonian rats.

artículo científico publicado en 2015

Peroxiredoxin 1 functions as a signal peroxidase to receive, transduce, and transmit peroxide signals in mammalian cells

artículo científico publicado en 2012

RNA-Sequencing Analysis Reveals a Regulatory Role for Transcription Factor Fezf2 in the Mature Motor Cortex

artículo científico publicado en 2017

Recent studies of ovine neuronal ceroid lipofuscinoses from BARN, the Batten Animal Research Network

artículo científico publicado en 2015

Secreted Amyloid Precursor Protein Alpha (sAPPα) Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes

artículo científico publicado en 2023

Secreted Amyloid Precursor Protein Alpha, a Neuroprotective Protein in the Brain Has Widespread Effects on the Transcriptome and Proteome of Human Inducible Pluripotent Stem Cell-Derived Glutamatergic Neurons Related to Memory Mechanisms

artículo científico publicado en 2022

The Tripeptide RER Mimics Secreted Amyloid Precursor Protein-Alpha in Upregulating LTP

artículo científico publicado en 2019

The contribution of multicellular model organisms to neuronal ceroid lipofuscinosis research

artículo científico publicado en 2019

Transcriptome Profiling of Layer 5 Intratelencephalic Projection Neurons From the Mature Mouse Motor Cortex

scholarly article by Alison J Clare published in January 2018

Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors

artículo científico publicado en 2000

Transduction of neurons lining the cerebral external capsules in mice with feline immunodeficiency virus based vectors

artículo científico publicado el 13 de noviembre de 2003

Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease.

artículo científico publicado en 2006

Verification of functional AAV-mediated neurotrophic and anti-apoptotic factor expression.

artículo científico publicado en 2006

Viral vector-based tools advance knowledge of basal ganglia anatomy and physiology

artículo científico publicado en 2016

Viral-mediated gene transfer to mouse primary neural progenitor cells.

artículo científico publicado en 2002

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico