Lista de obras - Robert Nistico - Dominio Público Uruguay

5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice

artículo científico publicado en 2015

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

scientific article published on 31 March 2020

A healthy gut for a healthy brain: preclinical, clinical and regulatory as-pects

artículo científico publicado en 2020

A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus.

artículo científico publicado en 2003

ACET is a highly potent and specific kainate receptor antagonist: Characterisation and effects on hippocampal mossy fibre function

artículo científico publicado en 2009

Abnormal expression of neuronal nitric oxide synthase triggers limbic seizures and hippocampal damage in rat.

artículo científico publicado en 2002

Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice

artículo científico publicado en 2014

Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the future

artículo científico publicado en 2014

Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR.

artículo científico publicado en 2013

Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease

artículo científico publicado en 2014

Apoptosis in the dorsal lateral geniculate nucleus after monocular deprivation involves glutamate signaling, NO production, and PARP activation

artículo científico publicado en 2000

Apoptosis in the mechanisms of neuronal plasticity in the developing visual system

artículo científico publicado en 2003

Apoptosis induced by gp120 in the neocortex of rat involves enhanced expression of cyclooxygenase type 2 and is prevented by NMDA receptor antagonists and by the 21-aminosteroid U-74389G.

artículo científico publicado en 2000

Biological Mechanism-based Neurology and Psychiatry: a BACE1/2 and Downstream Pathway Model

artículo científico publicado en 2021

Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease

artículo científico publicado en 2013

Central cardiovascular responses induced by interleukin 1 beta and tumor necrosis factor alpha infused into nucleus tractus solitarii, nucleus parabrachialis medialis and third cerebral ventricle of normotensive rats.

artículo científico publicado en 2001

Cerebrospinal Fluid Neurogranin as a Biomarker of Neurodegenerative Diseases: A Cross-Sectional Study

artículo científico publicado en 2017

Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer's disease

artículo científico publicado en 2020

Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome

artículo científico publicado en 2014

Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist

artículo científico publicado en 2004

Cognitive impairment and dentate gyrus synaptic dysfunction in experimental parkinsonism

artículo científico publicado en 2013

Connexin 26 (GJB2) mutations, causing KID Syndrome, are associated with cell death due to calcium gating deregulation.

artículo científico publicado en 2010

D-aspartate: an atypical amino acid with neuromodulatory activity in mammals

artículo científico publicado en 2009

Dexamethasone inhibits the inducible bioconversion of glyceryl trinitrate to nitric oxide.

artículo científico publicado en 2002

Differential effect of carbamazepine and oxcarbazepine on excitatory synaptic transmission in rat hippocampus

artículo científico publicado en 2008

Early Alteration of Distribution and Activity of Hippocampal Type-1 Cannabinoid Receptor in Alzheimer's Disease-like Mice Overexpressing the Human Mutant Amyloid Precursor Protein.

artículo científico publicado en 2018

Editorial: targeting synaptic dysfunction and neural connectivity in neurological and psychiatric disorders.

artículo científico publicado en 2013

Effects of intranasally-delivered pro-nerve growth factors on the septo-hippocampal system in healthy and diabetic rats

artículo científico publicado en 2020

Electrophysiological and metabolic effects of CHF5074 in the hippocampus: Protection against in vitro ischemia

artículo científico publicado en 2014

Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats

artículo científico publicado en 2012

Ethanol enhances GABAB-mediated inhibitory postsynaptic transmission on rat midbrain dopaminergic neurons by facilitating GIRK currents

artículo científico publicado en 2009

Evidence that increases of mitochondrial immunoreactive IL-1β by HIV-1 gp120 implicatein situcleavage of pro-IL-1β in the neocortex of rat

article

Evidence that the HIV-1 coat protein gp120 causes neuronal apoptosis in the neocortex of rat via a mechanism involving CXCR4 chemokine receptor

artículo científico publicado en 2001

Excitotoxic mechanisms of apoptosis in the mammalian visual system following monocular visual deprivation.

artículo científico publicado en 2002

Exploitation of the HIV-1 coat glycoprotein, gp120, in neurodegenerative studies in vivo.

artículo científico publicado en 2001

Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals

artículo científico publicado en 2014

GLUK1 receptor antagonists and hippocampal mossy fiber function

artículo científico publicado en 2009

Gender difference in prescription opioid abuse: A focus on oxycodone and hydrocodone

artículo científico publicado en 2016

Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy

artículo científico publicado en 2015

Genders and the concurrent use of cocaine and alcohol: Pharmacological aspects.

artículo científico

Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus.

artículo científico publicado en 2016

Growth factors and synaptic plasticity in relapsing-remitting multiple sclerosis.

artículo científico publicado en 2014

HIV-1 Coat Glycoprotein gp120 Induces Apoptosis in Rat Brain Neocortex by Deranging the Arachidonate Cascade in Favor of Prostanoids

artículo científico publicado en 2001

HIV-1 gp120-induced apoptosis in the rat neocortex involves enhanced expression of cyclo-oxygenase type 2 (COX-2).

artículo científico publicado en 1998

Huperzine a restores cortico-hippocampal functional connectivity after bilateral AMPA lesion of the nucleus basalis of meynert.

artículo científico publicado en 2013

Increased D-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice.

artículo científico publicado en 2010

Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility

artículo científico publicado en 2007

Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis.

artículo científico publicado en 2013

Inhibition of hippocampal plasticity in rats performing contrafreeloading for water under repeated administrations of pramipexole

artículo científico publicado en 2015

Insulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory.

artículo científico publicado en 2012

Integrating molecular mechanisms with synaptic plasticity in neurological disease

artículo científico publicado en 2012

Interleukin-1β promotes long-term potentiation in patients with multiple sclerosis.

artículo científico publicado en 2013

Involvement of interleukin-1beta in the mechanism of human immunodeficiency virus type 1 (HIV-1) recombinant protein gp120-induced apoptosis in the neocortex of rat.

artículo científico publicado en 1999

Kainate receptors and mossy fiber LTP.

artículo científico publicado en 2005

L-DOPA: a scapegoat for accelerated neurodegeneration in Parkinson's disease?

artículo científico publicado en 2011

Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease

artículo científico publicado en 2010

Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740.

artículo científico publicado en 2014

Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective

scientific article published on 01 January 2019

Multifaceted roles of nitric oxide in the lateral geniculate nucleus: from visual signal transduction to neuronal apoptosis

artículo científico publicado en 2003

N-ethyl lidocaine (QX-314) protects striatal neurons against ischemia: an in vitro electrophysiological study.

artículo científico publicado en 2010

Na+ -Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory

scientific journal article

Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory

artículo científico publicado en 2018

New insights on the role of free D-aspartate in the mammalian brain

artículo científico publicado en 2012

Oxidative stress in stroke pathophysiology validation of hydrogen peroxide metabolism as a pharmacological target to afford neuroprotection.

artículo científico publicado en 2009

PDGF Modulates Synaptic Excitability and Short-Latency Afferent Inhibition in Multiple Sclerosis.

artículo científico publicado en 2018

Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate

artículo científico publicado en 2013

Persistent increase of D-aspartate in D-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay.

artículo científico publicado en 2009

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020.

artículo científico publicado en 2013

Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions.

artículo científico publicado en 2013

Potential therapeutic usefulness of hydrogen peroxide in conditions of brain ischemia

artículo científico publicado en 2008

Precision medicine and drug development in Alzheimer's disease: the importance of sexual dimorphism and patient stratification

scientific article published on 12 June 2018

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release.

artículo científico publicado en 2015

Profile of gantenerumab and its potential in the treatment of Alzheimer's disease

artículo científico publicado en 2013

RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis.

artículo científico publicado en 2016

Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia.

artículo científico publicado en 2014

Reversal of metabolic and neurological symptoms of phenylketonuric mice treated with a PAH containing helper-dependent adenoviral vector

artículo científico publicado en 2012

Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology.

artículo científico publicado en 2018

Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion.

artículo científico publicado en 2015

Role of ASIC1a in Normal and Pathological Synaptic Plasticity

scientific article published on 14 August 2020

Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine

artículo científico publicado en 2010

SUMO: a (oxidative) stressed protein.

artículo científico publicado en 2013

SUMOylation in neuroplasticity and neurological disorders.

artículo científico publicado en 2013

Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins.

artículo científico publicado en 2013

Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity.

artículo científico publicado en 2015

Subtle alterations of excitatory transmission are linked to presynaptic changes in the hippocampus of PINK1-deficient mice.

artículo científico publicado en 2016

Synaptic plasticity and PDGF signaling defects underlie clinical progression in multiple sclerosis.

artículo científico publicado en 2013

Synaptic plasticity as a therapeutic target in the treatment of autism-related single-gene disorders.

artículo científico

Synaptic plasticity in multiple sclerosis and in experimental autoimmune encephalomyelitis.

artículo científico publicado en 2013

Synaptic plasticity in the basal ganglia: a similar code for physiological and pathological conditions.

artículo científico publicado en 2007

Synaptoimmunology - roles in health and disease.

artículo científico publicado en 2017

Synergistic interactions between kainate and mGlu receptors regulate bouton Ca signalling and mossy fibre LTP.

artículo científico publicado en 2011

Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors.

artículo científico publicado en 2005

Systemic administration of cocaine, given alone or in combination with sensory stimuli, differentially affects L-arginine-nitric oxide metabolism in discrete regions of the brain of rat.

artículo científico publicado en 1999

Targeting SUMO-1ylation Contrasts Synaptic Dysfunction in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2016

Targeting Synaptic Plasticity in Experimental Models of Alzheimer's Disease

scientific article published on 16 July 2019

Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria.

artículo científico publicado en 2018

Targeting synaptic dysfunction in Alzheimer's disease therapy.

artículo científico

The Involvement of Post-Translational Modifications in Alzheimer's Disease

artículo científico publicado en 2017

The blockade of K(+)-ATP channels has neuroprotective effects in an in vitro model of brain ischemia.

artículo científico publicado en 2007

The positive allosteric modulator at mGlu2 receptors, LY487379, reverses the effects of chronic stress-induced behavioral maladaptation and synaptic dysfunction in the adulthood

artículo científico publicado en 2019

The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils

artículo científico publicado en 2003

The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus.

artículo científico publicado en 2017

The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic

artículo científico publicado en 2003

The selective disruption of presynaptic JNK2/STX1a interaction reduces NMDA receptor-dependent glutamate release

artículo científico publicado en 2019

The β-Secretase BACE1 in Alzheimer's Disease

artículo científico publicado en 2020

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

artículo científico publicado en 2011

Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia. ⬇️

artículo científico publicado en 2012

Unbalance between Excitation and Inhibition in Phenylketonuria, a Genetic Metabolic Disease Associated with Autism

artículo científico publicado en 2017

Unlocking the secrets of dopamine in Alzheimer's Disease

artículo científico publicado en 2017

Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia

artículo científico publicado en 2015

d-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain.

artículo científico publicado en 2015

Lista de obras de Robert Nistico

5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

A healthy gut for a healthy brain: preclinical, clinical and regulatory as-pects

A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus.

ACET is a highly potent and specific kainate receptor antagonist: Characterisation and effects on hippocampal mossy fibre function

Abnormal expression of neuronal nitric oxide synthase triggers limbic seizures and hippocampal damage in rat.

Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice

Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the future

Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR.

Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease

Apoptosis in the dorsal lateral geniculate nucleus after monocular deprivation involves glutamate signaling, NO production, and PARP activation

Apoptosis in the mechanisms of neuronal plasticity in the developing visual system

Apoptosis induced by gp120 in the neocortex of rat involves enhanced expression of cyclooxygenase type 2 and is prevented by NMDA receptor antagonists and by the 21-aminosteroid U-74389G.

Biological Mechanism-based Neurology and Psychiatry: a BACE1/2 and Downstream Pathway Model

Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease

Central cardiovascular responses induced by interleukin 1 beta and tumor necrosis factor alpha infused into nucleus tractus solitarii, nucleus parabrachialis medialis and third cerebral ventricle of normotensive rats.

Cerebrospinal Fluid Neurogranin as a Biomarker of Neurodegenerative Diseases: A Cross-Sectional Study

Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer's disease

Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome

Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist

Cognitive impairment and dentate gyrus synaptic dysfunction in experimental parkinsonism

Connexin 26 (GJB2) mutations, causing KID Syndrome, are associated with cell death due to calcium gating deregulation.

D-aspartate: an atypical amino acid with neuromodulatory activity in mammals

Dexamethasone inhibits the inducible bioconversion of glyceryl trinitrate to nitric oxide.

Differential effect of carbamazepine and oxcarbazepine on excitatory synaptic transmission in rat hippocampus

Early Alteration of Distribution and Activity of Hippocampal Type-1 Cannabinoid Receptor in Alzheimer's Disease-like Mice Overexpressing the Human Mutant Amyloid Precursor Protein.

Editorial: targeting synaptic dysfunction and neural connectivity in neurological and psychiatric disorders.

Effects of intranasally-delivered pro-nerve growth factors on the septo-hippocampal system in healthy and diabetic rats

Electrophysiological and metabolic effects of CHF5074 in the hippocampus: Protection against in vitro ischemia

Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats

Ethanol enhances GABAB-mediated inhibitory postsynaptic transmission on rat midbrain dopaminergic neurons by facilitating GIRK currents

Evidence that increases of mitochondrial immunoreactive IL-1β by HIV-1 gp120 implicatein situcleavage of pro-IL-1β in the neocortex of rat

Evidence that the HIV-1 coat protein gp120 causes neuronal apoptosis in the neocortex of rat via a mechanism involving CXCR4 chemokine receptor

Excitotoxic mechanisms of apoptosis in the mammalian visual system following monocular visual deprivation.

Exploitation of the HIV-1 coat glycoprotein, gp120, in neurodegenerative studies in vivo.

Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals

GLUK1 receptor antagonists and hippocampal mossy fiber function

Gender difference in prescription opioid abuse: A focus on oxycodone and hydrocodone

Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy

Genders and the concurrent use of cocaine and alcohol: Pharmacological aspects.

Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus.

Growth factors and synaptic plasticity in relapsing-remitting multiple sclerosis.

HIV-1 Coat Glycoprotein gp120 Induces Apoptosis in Rat Brain Neocortex by Deranging the Arachidonate Cascade in Favor of Prostanoids

HIV-1 gp120-induced apoptosis in the rat neocortex involves enhanced expression of cyclo-oxygenase type 2 (COX-2).

Huperzine a restores cortico-hippocampal functional connectivity after bilateral AMPA lesion of the nucleus basalis of meynert.

Increased D-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice.

Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility

Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis.

Inhibition of hippocampal plasticity in rats performing contrafreeloading for water under repeated administrations of pramipexole

Insulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory.

Integrating molecular mechanisms with synaptic plasticity in neurological disease

Interleukin-1β promotes long-term potentiation in patients with multiple sclerosis.

Involvement of interleukin-1beta in the mechanism of human immunodeficiency virus type 1 (HIV-1) recombinant protein gp120-induced apoptosis in the neocortex of rat.

Kainate receptors and mossy fiber LTP.

L-DOPA: a scapegoat for accelerated neurodegeneration in Parkinson's disease?

Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease

Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740.

Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective

Multifaceted roles of nitric oxide in the lateral geniculate nucleus: from visual signal transduction to neuronal apoptosis

N-ethyl lidocaine (QX-314) protects striatal neurons against ischemia: an in vitro electrophysiological study.

Na+ -Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory

Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory

New insights on the role of free D-aspartate in the mammalian brain

Oxidative stress in stroke pathophysiology validation of hydrogen peroxide metabolism as a pharmacological target to afford neuroprotection.

PDGF Modulates Synaptic Excitability and Short-Latency Afferent Inhibition in Multiple Sclerosis.

Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate

Persistent increase of D-aspartate in D-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay.

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020.

Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions.

Potential therapeutic usefulness of hydrogen peroxide in conditions of brain ischemia

Precision medicine and drug development in Alzheimer's disease: the importance of sexual dimorphism and patient stratification

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release.

Profile of gantenerumab and its potential in the treatment of Alzheimer's disease

RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis.

Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia.

Reversal of metabolic and neurological symptoms of phenylketonuric mice treated with a PAH containing helper-dependent adenoviral vector

Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology.

Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion.

Role of ASIC1a in Normal and Pathological Synaptic Plasticity