Lista de obras - Laura Leyva - Dominio Público Uruguay

A New Risk Variant for Multiple Sclerosis at 11q23.3 Locus Is Associated with Expansion of CXCR5+ Circulating Regulatory T Cells

artículo científico publicado en 2020

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

artículo científico publicado en 2015

A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands

artículo científico publicado en 2014

ANKRD55 and DHCR7 are novel multiple sclerosis risk loci

article

Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß.

artículo científico publicado en 2017

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study.

artículo científico publicado en 2018

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

artículo científico publicado en 2016

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation

scientific article published on 31 March 2020

Cell-based product classification procedure: What can be done differently to improve decisions on borderline products?

artículo científico publicado en 2016

Cross-reactivity of antibodies against interferon beta in multiple sclerosis patients and interference of the JAK-STAT signaling pathway

artículo científico publicado en 2017

DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands

artículo científico publicado en 2012

Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker.

artículo científico publicado en 2016

Development and validation of an ELISA for quantification of soluble IFN-β receptor: assessment in multiple sclerosis

artículo científico publicado en 2015

Differences in the immunological responses in drug- and virus-induced cutaneous reactions in children.

artículo científico publicado en 2003

Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression

artículo científico publicado en 2004

Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease

artículo científico publicado en 2019

Expression of the skin-homing receptor in peripheral blood lymphocytes from subjects with nonimmediate cutaneousallergic drug reactions

artículo científico publicado en 2000

Gene expression in IFNß signalling pathway differs between monocytes, CD4 and CD8 T cells from MS patients ⬇️

artículo científico publicado el 24 de noviembre de 2010

Gene therapy with mesenchymal stem cells expressing IFN-ß ameliorates neuroinflammation in experimental models of multiple sclerosis

artículo científico publicado en 2016

Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1

artículo científico publicado en 2012

Genome-wide significant association with seven novel multiple sclerosis risk loci

artículo científico publicado en 2015

Global methylation correlates with clinical status in multiple sclerosis patients in the first year of IFNbeta treatment

artículo científico publicado en 2017

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis

artículo científico publicado en 2014

HLA class II alleles in patients with multiple sclerosis in the Biscay province (Basque Country, Spain)

artículo científico publicado en 2009

HLA class II and response to interferon-beta in multiple sclerosis.

artículo científico publicado en 2005

Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis

artículo científico publicado en 2009

Human endogenous retrovirus HERV-Fc1 association with multiple sclerosis susceptibility: a meta-analysis

artículo científico publicado en 2014

IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response

artículo científico publicado en 2005

IL28B polymorphisms are not associated with the response to interferon-β in multiple sclerosis

scientific article published on 01 September 2011

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

artículo científico publicado en 2009

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

artículo científico publicado en 2012

In vitro T-cell responses to beta-lactam drugs in immediate and nonimmediate allergic reactions.

artículo científico publicado en 2001

Interferon receptor expression in multiple sclerosis patients.

artículo científico publicado en 2006

Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations

artículo científico publicado en 2008

Killer-cell immunoglobulin-like receptor expression on lymphocyte subsets in multiple sclerosis patients treated with interferon-β: evaluation as biomarkers for clinical response

artículo científico publicado en 2014

Kinetics and incidence of anti-natalizumab antibodies in multiple sclerosis patients on treatment for 18 months

scientific article published on 21 December 2010

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

artículo científico publicado en 2015

Multiple sclerosis association study with theTENR-IL2-IL21region in a Spanish population

article

Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association.

artículo científico publicado en 2008

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

artículo científico publicado en 2015

Predictors of Fatigue Severity in Early Systemic Sclerosis: A Prospective Longitudinal Study of the GENISOS Cohort ⬇️

artículo científico publicado el 14 de octubre de 2011

Preferential Expression of the Skin–Homing Receptor CLA in Peripheral T Lymphocytes from Patients with Drug–Allergic Reactions

artículo científico publicado en 1999

Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis.

artículo científico publicado en 2005

Recombinant soluble IFN receptor (sIFNAR2) exhibits intrinsic therapeutic efficacy in a murine model of Multiple Sclerosis

artículo científico publicado en 2016

Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.

artículo científico publicado en 2010

Study of binding and neutralising antibodies to interferon-beta in two groups of relapsing-remitting multiple sclerosis patients

artículo científico publicado en 2001

Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction

artículo científico publicado en 2000

TRAIL and TRAIL receptors splice variants during long-term interferon β treatment of patients with multiple sclerosis: evaluation as biomarkers for therapeutic response

artículo científico publicado en 2015

Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis

artículo científico publicado en 2010

The HLA DRB1*03:01 allele is associated with NMO regardless of the NMO-IgG status in Brazilian patients from Rio de Janeiro.

artículo científico publicado en 2017

The efficacy of natalizumab in patients with multiple sclerosis according to level of disability: results of an observational study.

artículo científico publicado en 2010

The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis

artículo científico publicado en 2008

Lista de obras de Laura Leyva

A New Risk Variant for Multiple Sclerosis at 11q23.3 Locus Is Associated with Expansion of CXCR5+ Circulating Regulatory T Cells

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands

ANKRD55 and DHCR7 are novel multiple sclerosis risk loci

Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß.

Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study.

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation

Cell-based product classification procedure: What can be done differently to improve decisions on borderline products?

Cross-reactivity of antibodies against interferon beta in multiple sclerosis patients and interference of the JAK-STAT signaling pathway

DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands

Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker.

Development and validation of an ELISA for quantification of soluble IFN-β receptor: assessment in multiple sclerosis

Differences in the immunological responses in drug- and virus-induced cutaneous reactions in children.

Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression

Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease

Expression of the skin-homing receptor in peripheral blood lymphocytes from subjects with nonimmediate cutaneousallergic drug reactions

Gene expression in IFNß signalling pathway differs between monocytes, CD4 and CD8 T cells from MS patients ⬇️

Gene therapy with mesenchymal stem cells expressing IFN-ß ameliorates neuroinflammation in experimental models of multiple sclerosis

Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1

Genome-wide significant association with seven novel multiple sclerosis risk loci

Global methylation correlates with clinical status in multiple sclerosis patients in the first year of IFNbeta treatment

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis

HLA class II alleles in patients with multiple sclerosis in the Biscay province (Basque Country, Spain)

HLA class II and response to interferon-beta in multiple sclerosis.

Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis

Human endogenous retrovirus HERV-Fc1 association with multiple sclerosis susceptibility: a meta-analysis

IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response

IL28B polymorphisms are not associated with the response to interferon-β in multiple sclerosis

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

In vitro T-cell responses to beta-lactam drugs in immediate and nonimmediate allergic reactions.

Interferon receptor expression in multiple sclerosis patients.

Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations

Killer-cell immunoglobulin-like receptor expression on lymphocyte subsets in multiple sclerosis patients treated with interferon-β: evaluation as biomarkers for clinical response

Kinetics and incidence of anti-natalizumab antibodies in multiple sclerosis patients on treatment for 18 months

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

Multiple sclerosis association study with theTENR-IL2-IL21region in a Spanish population

Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association.

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

Predictors of Fatigue Severity in Early Systemic Sclerosis: A Prospective Longitudinal Study of the GENISOS Cohort ⬇️

Preferential Expression of the Skin–Homing Receptor CLA in Peripheral T Lymphocytes from Patients with Drug–Allergic Reactions

Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis.

Recombinant soluble IFN receptor (sIFNAR2) exhibits intrinsic therapeutic efficacy in a murine model of Multiple Sclerosis

Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.

Study of binding and neutralising antibodies to interferon-beta in two groups of relapsing-remitting multiple sclerosis patients

Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction

TRAIL and TRAIL receptors splice variants during long-term interferon β treatment of patients with multiple sclerosis: evaluation as biomarkers for therapeutic response

Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis

The HLA DRB1*03:01 allele is associated with NMO regardless of the NMO-IgG status in Brazilian patients from Rio de Janeiro.

The efficacy of natalizumab in patients with multiple sclerosis according to level of disability: results of an observational study.

The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis