Lista de obras - Martina Kocan - Dominio Público Uruguay

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

scientific article published on 26 February 2016

AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis

scientific article published on 11 September 2019

Agonist-independent interactions between beta-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis.

artículo científico publicado en 2009

An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii

scientific article published on 16 April 2019

BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors without causing classical receptor desensitization

scientific article published on 20 March 2019

Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.

artículo científico publicado en 2014

Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein-coupled receptors in live cells

artículo científico publicado en 2008

Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology

artículo científico publicado en 2009

Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist

artículo científico publicado en 2016

Enhanced BRET Technology for the Monitoring of Agonist-Induced and Agonist-Independent Interactions between GPCRs and β-Arrestins

artículo científico publicado en 2010

INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells.

artículo científico publicado en 2018

Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression

artículo científico publicado en 2018

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.

artículo científico publicado en 2017

Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1.

artículo científico publicado en 2012

Minimum active structure of insulin-like peptide 5.

artículo científico publicado en 2013

Orthosteric, Allosteric and Biased Signalling at the Relaxin-3 Receptor RXFP3.

artículo científico publicado en 2015

Real-time examination of cAMP activity at relaxin family peptide receptors using a BRET-based biosensor

artículo científico publicado en 2018

Relaxin family peptides and their receptors

artículo científico

Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis

artículo científico publicado en 2014

Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor.

artículo científico publicado en 2016

Signalling profiles of H3 relaxin, H2 relaxin and R3(BΔ23-27)R/I5 acting at the relaxin family peptide receptor 3 (RXFP3)

artículo científico publicado en 2014

Single chain peptide agonists of relaxin receptors

scientific article published on 11 January 2019

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins

artículo científico publicado en 2017

Study of GPCR–Protein Interactions by BRET ⬇️

artículo científico publicado el 1 de enero de 2011

The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor, Diethylamine NONOate.

artículo científico publicado en 2016

The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity

artículo científico publicado en 2015

The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4.

artículo científico publicado en 2016

The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.

scientific article published on July 2013

The relaxin receptor as a therapeutic target - perspectives from evolution and drug targeting

artículo científico publicado en 2018

Two-component systems of Corynebacterium glutamicum: deletion analysis and involvement of the PhoS-PhoR system in the phosphate starvation response.

artículo científico publicado en 2006

Understanding relaxin signalling at the cellular level

artículo científico publicado en 2018

Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis

scientific article published on 30 July 2019

β2‐Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C‐terminal tail ⬇️

artículo científico publicado el 1 de marzo de 2012

Lista de obras de Martina Kocan

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis

Agonist-independent interactions between beta-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis.

An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii

BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors without causing classical receptor desensitization

Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.

Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein-coupled receptors in live cells

Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology

Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist

Enhanced BRET Technology for the Monitoring of Agonist-Induced and Agonist-Independent Interactions between GPCRs and β-Arrestins

INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells.

Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.

Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1.

Minimum active structure of insulin-like peptide 5.

Orthosteric, Allosteric and Biased Signalling at the Relaxin-3 Receptor RXFP3.

Real-time examination of cAMP activity at relaxin family peptide receptors using a BRET-based biosensor

Relaxin family peptides and their receptors

Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis

Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor.

Signalling profiles of H3 relaxin, H2 relaxin and R3(BΔ23-27)R/I5 acting at the relaxin family peptide receptor 3 (RXFP3)

Single chain peptide agonists of relaxin receptors

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins

Study of GPCR–Protein Interactions by BRET ⬇️

The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor, Diethylamine NONOate.

The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity

The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4.

The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.

The relaxin receptor as a therapeutic target - perspectives from evolution and drug targeting

Two-component systems of Corynebacterium glutamicum: deletion analysis and involvement of the PhoS-PhoR system in the phosphate starvation response.

Understanding relaxin signalling at the cellular level

Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis

β2‐Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C‐terminal tail ⬇️