Lista de obras - Genevieve Pratviel - Dominio Público Uruguay

1'-carbon hydroxylation of deoxyribose as the mechanism of cleavage of poly(dA) by manganese porphyrin combined with potassium monopersulfate

artículo científico publicado en 1989

8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases

scientific article published on 01 August 2018

A G-Quadruplex Ligand with 10000-Fold Selectivity over Duplex DNA

scientific article published on 01 February 2007

A single nuclease-resistant linkage in DNA as a versatile tool for the characterization of DNA lesions: application to the guanine oxidative lesion "G+34" generated by metalloporphyrin/KHSO(5) reagent

Cationic Porphyrin-Anionic Surfactant Mixtures for the Promotion of Self-Organized 1:4 Ion Pairs in Water with Strong Aggregation Properties

artículo científico publicado en 2015

Characterization of the dehydro-guanidinohydantoin oxidation product of guanine in a dinucleotide.

artículo científico publicado en 2002

Cleavage of double-stranded DNA by 'metalloporphyrin-linker-oligonucleotide' molecules: influence of the linker.

artículo científico publicado en 1995

Cobalt(III)porphyrin to target G-quadruplex DNA.

artículo científico publicado en 2015

Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes

scientific article published on 31 July 2019

Comparative Study of the Phototoxicity of Long-Wavelength Photosensitizers Targeted by the MornigaG Lectin

artículo científico publicado en 2011

Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe.

artículo científico

Concept for simultaneous and specific in situ monitoring of amyloid oligomers and fibrils via Förster resonance energy transfer

artículo científico publicado en 2014

Convenient method for the preparation of 2'-deoxyribosylurea by thymidine oxidation and NMR study of both anomers.

artículo científico publicado en 2001

Cross-docking study on InhA inhibitors: a combination of Autodock Vina and PM6-DH2 simulations to retrieve bio-active conformations

artículo científico publicado en 2012

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

artículo científico publicado en 2015

Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype

artículo científico publicado en 1989

DNA breaks generated by the bleomycin-iron III complex in the presence of KHSO5, a single oxygen donor

scientific article published on 01 May 1986

Dendrislides, dendrichips: a simple chemical functionalization of glass slides with phosphorus dendrimers as an effective means for the preparation of biochips

article by Emmanuelle Trévisiol et al published 2003 in New Journal of Chemistry

Ethionamide biomimetic activation and an unprecedented mechanism for its conversion into active and non-active metabolites

artículo científico publicado en 2016

Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis

artículo científico publicado en 2016

Formation of the carboxamidine precursor of cyanuric acid from guanine oxidative lesion dehydro-guanidinohydantoin

artículo científico publicado en 2014

G-Quadruplex binding optimization by gold(iii) insertion into the center of a porphyrin

scientific article published on 01 May 2019

Guanine Oxidation in Double-stranded DNA by MnTMPyP/KHSO(5): At Least Three Independent Reaction Pathways.

artículo científico publicado en 2001

Guanine oxidation: NMR characterization of a dehydro-guanidinohydantoin residue generated by a 2e-oxidation of d(GpT).

artículo científico publicado en 2001

Guanine oxidation: one- and two-electron reactions

scientific article published on 01 August 2006

Guanosine in a single stranded region of anticodon stem-loop tRNA models is prone to oxidatively generated damage resulting in dehydroguanidinohydantoin and spiroiminodihydantoin lesions

artículo científico publicado en 2015

Influence of the nature of the porphyrin ligand on the nuclease activity of metalloporphyrin-oligonucleotide conjugates designed with cationic, hydrophobic or anionic metalloporphyrins.

artículo científico publicado en 1997

Ionic Polypeptide Polymers with Unusual β-Sheet Stability

Mapping and characterization of G-quadruplexes in the genome of the social amoeba Dictyostelium discoideum

artículo científico publicado en 2019

Microstructured liposome array

artículo científico publicado en 2006

Modification of the thiourea linkage of a fluorescein-oligonucleotide conjugate to a guanidinium motif during ammonia deprotection

scientific article published on 01 September 1998

Novel 8-nitroquinolin-2(1 H )-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study

artículo científico publicado en 2018

Nucleopolypeptides with DNA-triggered α helix-to-β sheet transition.

artículo científico publicado en 2017

Oxidation of 5-methylaminomethyl uridine (mnm⁵U) by Oxone Leads to Aldonitrone Derivatives.

artículo científico publicado en 2018

Oxidative DNA damage mediated by transition metal ions and their complexes.

artículo científico

Oxidative damage generated by an oxo-metalloporphyrin onto the human telomeric sequence

artículo científico publicado en 2000

Porphyrin Derivatives for Telomere Binding and Telomerase Inhibition

artículo científico publicado en 2005

Porphyrin-aminoquinoline conjugates as telomerase inhibitors.

artículo científico publicado en 2003

Potassium monopersulfate and a water-soluble manganese porphyrin complex, [Mn(TMPyP)](OAc)5, as an efficient reagent for the oxidative cleavage of DNA

artículo científico publicado en 1989

Preferential hydroxylation by the chemical nuclease meso-tetrakis-(4-N-methylpyridiniumyl)porphyrinatomanganeseIII pentaacetate/KHSO5 at the 5' carbon of deoxyriboses on both 3' sides of three contiguous A.T base pairs in short double-stranded oligo ⬇️

artículo científico publicado el 1 de mayo de 1992

Preparation and nuclease activity of hybrid "metallotris(methylpyridinium)porphyrin oligonucleotide" molecules having a 3'-loop for protection against 3'-exonucleases.

artículo científico publicado en 1995

Selective DNA cleavage by metalloporphyrin derivatives.

artículo científico publicado en 1996

Smart Poly(imidazoyl-l-lysine): Synthesis and Reversible Helix-to-Coil Transition at Neutral pH

artículo científico publicado en 2017

Spontaneous reduction of mixed 2,2'-bipyridine/methylamine/chloro complexes of Pt(IV) in water in the presence of light is accompanied by complex isomerization, loss of methylamine, and formation of a strong oxidant, presumably HOCl.

artículo científico publicado en 2007

Structure/nuclease activity relationships of DNA cleavers based on cationic metalloporphyrin-oligonucleotide conjugates

scientific article published on 01 July 1996

Structures of Fe(II) Complexes with N,N,N'-Tris(2-pyridylmethyl)ethane-1,2-diamine Type Ligands. Bleomycin-like DNA Cleavage and Enhancement by an Alkylammonium Substituent on the N' Atom of the Ligand

scientific article published on 01 March 1999

Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.

artículo científico publicado en 2017

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells

artículo científico publicado en 2015

The pKa value of the proximal water molecule trans to a high-valent MnV[double bond, length as m-dash]O porphyrin: towards the control of reactivity by pH.

artículo científico publicado en 2017

Use of short duplexes for the analysis of the sequence-dependent cleavage of DNA by a chemical nuclease, a manganese porphyrin.

artículo científico publicado en 2005

Lista de obras de Genevieve Pratviel

1'-carbon hydroxylation of deoxyribose as the mechanism of cleavage of poly(dA) by manganese porphyrin combined with potassium monopersulfate

8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases

A G-Quadruplex Ligand with 10000-Fold Selectivity over Duplex DNA

A single nuclease-resistant linkage in DNA as a versatile tool for the characterization of DNA lesions: application to the guanine oxidative lesion "G+34" generated by metalloporphyrin/KHSO(5) reagent

Cationic Porphyrin-Anionic Surfactant Mixtures for the Promotion of Self-Organized 1:4 Ion Pairs in Water with Strong Aggregation Properties

Characterization of the dehydro-guanidinohydantoin oxidation product of guanine in a dinucleotide.

Cleavage of double-stranded DNA by 'metalloporphyrin-linker-oligonucleotide' molecules: influence of the linker.

Cobalt(III)porphyrin to target G-quadruplex DNA.

Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes

Comparative Study of the Phototoxicity of Long-Wavelength Photosensitizers Targeted by the MornigaG Lectin

Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe.

Concept for simultaneous and specific in situ monitoring of amyloid oligomers and fibrils via Förster resonance energy transfer

Convenient method for the preparation of 2'-deoxyribosylurea by thymidine oxidation and NMR study of both anomers.

Cross-docking study on InhA inhibitors: a combination of Autodock Vina and PM6-DH2 simulations to retrieve bio-active conformations

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype

DNA breaks generated by the bleomycin-iron III complex in the presence of KHSO5, a single oxygen donor

Dendrislides, dendrichips: a simple chemical functionalization of glass slides with phosphorus dendrimers as an effective means for the preparation of biochips

Ethionamide biomimetic activation and an unprecedented mechanism for its conversion into active and non-active metabolites

Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis

Formation of the carboxamidine precursor of cyanuric acid from guanine oxidative lesion dehydro-guanidinohydantoin

G-Quadruplex binding optimization by gold(iii) insertion into the center of a porphyrin

Guanine Oxidation in Double-stranded DNA by MnTMPyP/KHSO(5): At Least Three Independent Reaction Pathways.

Guanine oxidation: NMR characterization of a dehydro-guanidinohydantoin residue generated by a 2e-oxidation of d(GpT).

Guanine oxidation: one- and two-electron reactions

Guanosine in a single stranded region of anticodon stem-loop tRNA models is prone to oxidatively generated damage resulting in dehydroguanidinohydantoin and spiroiminodihydantoin lesions

Influence of the nature of the porphyrin ligand on the nuclease activity of metalloporphyrin-oligonucleotide conjugates designed with cationic, hydrophobic or anionic metalloporphyrins.

Ionic Polypeptide Polymers with Unusual β-Sheet Stability

Mapping and characterization of G-quadruplexes in the genome of the social amoeba Dictyostelium discoideum

Microstructured liposome array

Modification of the thiourea linkage of a fluorescein-oligonucleotide conjugate to a guanidinium motif during ammonia deprotection

Novel 8-nitroquinolin-2(1 H )-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study

Nucleopolypeptides with DNA-triggered α helix-to-β sheet transition.

Oxidation of 5-methylaminomethyl uridine (mnm⁵U) by Oxone Leads to Aldonitrone Derivatives.

Oxidative DNA damage mediated by transition metal ions and their complexes.

Oxidative damage generated by an oxo-metalloporphyrin onto the human telomeric sequence

Porphyrin Derivatives for Telomere Binding and Telomerase Inhibition

Porphyrin-aminoquinoline conjugates as telomerase inhibitors.

Potassium monopersulfate and a water-soluble manganese porphyrin complex, [Mn(TMPyP)](OAc)5, as an efficient reagent for the oxidative cleavage of DNA

Preferential hydroxylation by the chemical nuclease meso-tetrakis-(4-N-methylpyridiniumyl)porphyrinatomanganeseIII pentaacetate/KHSO5 at the 5' carbon of deoxyriboses on both 3' sides of three contiguous A.T base pairs in short double-stranded oligo ⬇️

Preparation and nuclease activity of hybrid "metallotris(methylpyridinium)porphyrin oligonucleotide" molecules having a 3'-loop for protection against 3'-exonucleases.

Selective DNA cleavage by metalloporphyrin derivatives.

Smart Poly(imidazoyl-l-lysine): Synthesis and Reversible Helix-to-Coil Transition at Neutral pH

Spontaneous reduction of mixed 2,2'-bipyridine/methylamine/chloro complexes of Pt(IV) in water in the presence of light is accompanied by complex isomerization, loss of methylamine, and formation of a strong oxidant, presumably HOCl.

Structure/nuclease activity relationships of DNA cleavers based on cationic metalloporphyrin-oligonucleotide conjugates

Structures of Fe(II) Complexes with N,N,N'-Tris(2-pyridylmethyl)ethane-1,2-diamine Type Ligands. Bleomycin-like DNA Cleavage and Enhancement by an Alkylammonium Substituent on the N' Atom of the Ligand

Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells

The pKa value of the proximal water molecule trans to a high-valent MnV[double bond, length as m-dash]O porphyrin: towards the control of reactivity by pH.

Use of short duplexes for the analysis of the sequence-dependent cleavage of DNA by a chemical nuclease, a manganese porphyrin.