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A microRNA signature that correlates with cognition and is a target against cognitive decline

artículo científico publicado en 2021

A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.

artículo científico publicado en 2018

A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2

scientific article published on 15 September 2019

Activation of the NLRP3 inflammasome in microglia: The role of ceramide

artículo científico publicado en 2017

CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume

artículo científico publicado en 2018

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

artículo científico publicado en 2021

Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).

artículo científico publicado en 2018

Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition

Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice

artículo científico publicado el 10 de marzo de 2011

Do infections have a role in the pathogenesis of Alzheimer disease?

scientific article published on 09 March 2020

Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression

artículo científico publicado en 2019

Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis

artículo científico publicado en 2019

Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults

artículo científico publicado en 2019

IFN-β1a (Rebif®) Modifies the Expression of Microfilament-Associated Cell-Cell Contacts in C6 Glioma Cells

artículo científico publicado el 1 de febrero de 2003

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

scientific article published on 04 June 2020

Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid binding protein 3 and ferritin to neurodegeneration and neuroinflammation

artículo científico publicado en 2020

Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes

artículo científico publicado en 2014

Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease

artículo científico publicado en 2018

Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment

scientific article published on 05 September 2019

Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease

artículo científico publicado en 2017

Microglia take centre stage in neurodegenerative disease

scientific article published on 01 February 2019

Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology

artículo científico publicado en 2021

Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer’s Disease

artículo científico publicado en 2018

Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness

artículo científico publicado en 2019

Norepinephrine as a modulator of microglial dynamics

scientific article published on 01 November 2019

Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples

scholarly article by Steffen Wolfsgruber et al published 17 January 2019 in Alzheimers Research & Therapy

Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease

artículo científico publicado en 2019

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

artículo científico publicado en 2014

Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes

artículo científico publicado en 2021

SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation

artículo científico publicado en 2021

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease

artículo científico publicado en 2014

Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies

artículo científico publicado en 2018

Soluble Aβ oligomers and protofibrils induce NLRP3 inflammasome activation in microglia

scientific article published on 23 December 2019

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

artículo científico publicado el 28 de septiembre de 2010

Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome

artículo científico publicado en 2019

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

scientific article published on 23 December 2016

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

artículo científico publicado en 2014

Tau plasma levels in subjective cognitive decline: Results from the DELCODE study

artículo científico publicado en 2017

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

artículo científico publicado en 2011

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease

scientific article published on 21 March 2019

Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey

scientific article published on 22 August 2019

Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study

artículo científico publicado en 2019

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers

artículo científico publicado en 2016