Lista de obras - Ann C Williams - Dominio Público Uruguay

A single human colonic adenoma cell line can be converted in vitro to both a colorectal adenocarcinoma and a mucinous carcinoma

artículo científico publicado el 19 de junio de 1992

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

artículo científico publicado en 2014

An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis.

artículo científico publicado en 1999

Apoptosis and disease: a life or death decision

artículo científico publicado en 2004

Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer.

artículo científico publicado en 1990

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

artículo científico publicado en 2013

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis

artículo científico publicado en 2011

BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity

artículo científico

BAG-1L promotes keratinocyte differentiation in organotypic culture models and changes in relative BAG-1 isoform abundance may lead to defective stratification.

artículo científico publicado en 2011

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling

artículo científico publicado en 2016

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells

scientific article published on 04 March 2019

Bax inhibitor 1 in apoptosis and disease.

artículo científico publicado en 2011

Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

artículo científico publicado en 2018

Cannabinoids and cancer: potential for colorectal cancer therapy: Table 1

article by Patsos HA et al published 1 August 2005 in Biochemical Society Transactions

Cell and molecular biology of gastrointestinal tract cancer

artículo científico publicado el 1 de agosto de 1992

Circulating prostaglandins as biomarkers for colorectal cancer?

artículo científico publicado en 2015

Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation

artículo científico publicado en 2011

Colorectal carcinogenesis: sequential steps in the in vitro immortalization and transformation of human colonic epithelial cells (review).

artículo científico publicado en 1990

Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor beta (TGF-beta): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-

artículo científico publicado en 1991

Direct Transcriptional Up-regulation of Cyclooxygenase-2 by Hypoxia-Inducible Factor (HIF)-1 Promotes Colorectal Tumor Cell Survival and Enhances HIF-1 Transcriptional Activity during Hypoxia

scientific article published on 01 July 2006

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours

artículo científico publicado en 2003

HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells

artículo científico publicado en 2009

Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment

artículo científico publicado en 2004

IGFBP-3 and apoptosis--a license to kill?

artículo científico publicado en 2001

In vitro models for studying colorectal carcinogenesis: cellular and molecular events including APC and Rb cleavage in the control of proliferation, differentiation and apoptosis.

artículo científico publicado en 1996

Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence

artículo científico publicado en 2006

Increased p53-dependent apoptosis by the insulin-like growth factor binding protein IGFBP-3 in human colonic adenoma-derived cells

artículo científico publicado en 2000

Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells.

artículo científico publicado en 2006

Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB.

artículo científico publicado en 2006

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

artículo científico publicado en 2007

Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia?

artículo científico publicado en 2007

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells

scientific article published on 10 January 2019

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity

artículo científico publicado en 2017

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs

artículo científico publicado en 2013

Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer

artículo científico publicado en 2006

Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate.

artículo científico publicado en 1997

Molecular events including p53 and k-ras alterations in the in vitro progression of a human colorectal adenoma cell line to an adenocarcinoma.

artículo científico publicado en 1993

Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.

artículo científico publicado en 1990

Nuclear BAG-1 expression inhibits apoptosis in colorectal adenoma-derived epithelial cells.

artículo científico publicado en 2005

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

artículo científico publicado en 2015

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.

artículo científico publicado en 2018

Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy.

artículo científico publicado en 2017

Promotability and tissue specificity of hereditary cancer genes: do hereditary cancer patients have a reduced requirement for tumor promotion because all their somatic cells are heterozygous at the predisposing locus?

artículo científico publicado en 1992

Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells

artículo científico publicado en 2007

Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential ⬇️

artículo científico publicado el 1 de noviembre de 1991

Specific cytogenetic abnormalities and k-ras mutation in two new human colorectal-adenoma-derived cell lines

artículo científico publicado el 11 de noviembre de 1992

Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis

artículo científico publicado en 2007

TGF-β1 signalling, connecting aberrant inflammation and colorectal tumorigenesis

artículo científico publicado en 2012

Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?

artículo científico publicado en 2018

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

scientific article published on 09 January 2009

The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells

artículo científico publicado en 2015

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells

artículo científico publicado en 2007

The effect of different TP53 mutations on the chromosomal stability of a human colonic adenoma derived cell line with endogenous wild type TP53 activity, before and after DNA damage.

artículo científico publicado en 1997

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2.

artículo científico publicado en 2005

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.

artículo científico publicado en 2010

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells.

artículo científico publicado en 2012

The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines

artículo científico publicado en 2003

The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival

artículo científico publicado en 2005

p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit

artículo científico publicado en 2014

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?

artículo científico publicado en 2012

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

artículo científico publicado en 2011

Lista de obras de Ann C Williams

A single human colonic adenoma cell line can be converted in vitro to both a colorectal adenocarcinoma and a mucinous carcinoma

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis.

Apoptosis and disease: a life or death decision

Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer.

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis

BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity

BAG-1L promotes keratinocyte differentiation in organotypic culture models and changes in relative BAG-1 isoform abundance may lead to defective stratification.

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells

Bax inhibitor 1 in apoptosis and disease.

Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

Cannabinoids and cancer: potential for colorectal cancer therapy: Table 1

Cell and molecular biology of gastrointestinal tract cancer

Circulating prostaglandins as biomarkers for colorectal cancer?

Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation

Colorectal carcinogenesis: sequential steps in the in vitro immortalization and transformation of human colonic epithelial cells (review).

Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor beta (TGF-beta): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-

Direct Transcriptional Up-regulation of Cyclooxygenase-2 by Hypoxia-Inducible Factor (HIF)-1 Promotes Colorectal Tumor Cell Survival and Enhances HIF-1 Transcriptional Activity during Hypoxia

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours

HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells

Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment

IGFBP-3 and apoptosis--a license to kill?

In vitro models for studying colorectal carcinogenesis: cellular and molecular events including APC and Rb cleavage in the control of proliferation, differentiation and apoptosis.

Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence

Increased p53-dependent apoptosis by the insulin-like growth factor binding protein IGFBP-3 in human colonic adenoma-derived cells

Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells.

Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB.

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia?

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs

Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer

Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate.

Molecular events including p53 and k-ras alterations in the in vitro progression of a human colorectal adenoma cell line to an adenocarcinoma.

Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.

Nuclear BAG-1 expression inhibits apoptosis in colorectal adenoma-derived epithelial cells.

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.

Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy.

Promotability and tissue specificity of hereditary cancer genes: do hereditary cancer patients have a reduced requirement for tumor promotion because all their somatic cells are heterozygous at the predisposing locus?

Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells

Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential ⬇️

Specific cytogenetic abnormalities and k-ras mutation in two new human colorectal-adenoma-derived cell lines

Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis

TGF-β1 signalling, connecting aberrant inflammation and colorectal tumorigenesis

Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells

The effect of different TP53 mutations on the chromosomal stability of a human colonic adenoma derived cell line with endogenous wild type TP53 activity, before and after DNA damage.

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2.

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells.

The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines

The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival

p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells