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Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress.

artículo científico publicado en 2015

Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53.

artículo científico publicado en 2015

Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis.

artículo científico publicado en 2016

Impact of the combined loss of BOK, BAX and BAK on the hematopoietic system is slightly more severe than compound loss of BAX and BAK

artículo científico publicado en 2015

Physiological restraint of Bak by Bcl-xL is essential for cell survival

artículo científico publicado en 2016

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

artículo científico publicado en 2015

RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice.

artículo científico publicado en 2016

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

artículo científico publicado en 2014

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL.

artículo científico publicado en 2017

The combination of reduced MCL-1 and standard chemotherapeutics is tolerable in mice

artículo científico publicado en 2017

The rise of apoptosis: targeting apoptosis in hematologic malignancies

artículo científico publicado en 2018