Lista de obras - Joy M Burchell - Dominio Público Uruguay

A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4 transferase.

artículo científico publicado en 2004

A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas

artículo científico publicado en 1989

A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes

artículo científico publicado en 1989

An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas

scientific article published on 01 December 1999

Androgen-dependent synthesis of basic secretory proteins by the rat seminal vesicle ⬇️

artículo científico publicado el 15 de agosto de 1976

Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells.

artículo científico publicado en 2004

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

artículo científico publicado en 2013

Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis.

artículo científico publicado en 2011

Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases

artículo científico publicado en 2007

Breast carcinoma cell lysate-pulsed dendritic cells cross-prime MUC1-specific CD8+ T cells identified by peptide-MHC-class-I tetramers.

artículo científico publicado en 2004

Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case–control study of colorectal cancer in UK collaborative trial of ovarian cancer screening

artículo científico publicado en 2014

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

scientific article published on 04 November 2020

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer

artículo científico publicado en 2002

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer

artículo científico publicado en 2002

Characterizing the glycome of the mammalian immune system.

artículo científico publicado en 2008

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

artículo científico publicado en 2005

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

artículo científico publicado en 1996

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

artículo científico publicado en 2013

Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer

scientific article published on 01 December 1984

Differential effect of interferon on DNA synthesis, 2-deoxyglucose uptake and ornithine decarboxylase activity in 3T3 cells stimulated by polypeptide growth factors and tumor promotors.

artículo científico publicado en 1980

Effective immunotherapy of cancer in MUC1-transgenic mice using clonal cytotoxic T lymphocytes directed against an immunodominant MUC1 epitope.

artículo científico publicado en 2002

Effects of Testosterone on Sequence Complexity of Polyadenylated RNA from Rat Seminal Vesicle ⬇️

artículo científico publicado el 15 de noviembre de 1978

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

artículo científico publicado en 2015

Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma.

artículo científico publicado en 1998

Functional analysis of the transcription repressor PLU-1/JARID1B.

artículo científico publicado en 2007

Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells

artículo científico publicado en 2014

HMFG1 antigen: a new marker for carcinomatous meningitis

artículo científico publicado en 1989

Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat

scientific article published on 18 October 2006

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.

artículo científico publicado en 2012

Immunisation with 'naïve' syngeneic dendritic cells protects mice from tumour challenge.

artículo científico publicado en 2008

Immunological analysis of mucin molecules expressed by normal and malignant mammary epithelial cells

scientific article published on 01 September 1987

Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers

artículo científico publicado en 2017

Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.

artículo científico publicado en 2016

Intramuscular immunisation with MUC1 cDNA can protect C57 mice challenged with MUC1-expressing syngeneic mouse tumour cells

artículo científico publicado en 1996

JARID1/KDM5 demethylases as cancer targets?

artículo científico publicado en 2016

Lack of beta-casein production by human breast tumours revealed by monoclonal antibodies

artículo científico publicado en 1987

Latest developments in MUC1 immunotherapy.

artículo científico publicado en 2018

MUC1 immunotherapy.

artículo científico publicado en 2010

Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin

scientific article published on 01 October 1999

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

artículo científico publicado en 2008

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

artículo científico publicado en 1995

Microvesicle cargo of tumor-associated MUC1 to dendritic cells allows cross-presentation and specific carbohydrate processing.

artículo científico publicado en 2013

Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule

artículo científico publicado en 2015

Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: Production and reaction with cells in culture

article

NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3.

artículo científico publicado en 2002

O-linked glycosylation in the mammary gland: changes that occur during malignancy.

artículo científico publicado en 2001

O-linked mucin-type glycosylation in breast cancer

article from 2018

PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?

artículo científico publicado en 2002

PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis.

artículo científico publicado en 2003

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells ⬇️

artículo científico publicado el 28 de febrero de 2011

Production and characterization of monoclonal antibodies to human casein. A monoclonal antibody that cross-reacts with casein and alpha-lactalbumin

scientific article published on 01 January 1985

Radioimmunoscintigraphy of ovarian tumors using a new monoclonal antibody, SM-3

artículo científico publicado en 1990

Radioimmunoscintigraphy with technetium-99m-labelled monoclonal antibody, SM3, in gynaecological cancer

artículo científico publicado en 1993

Repurposing tin mesoporphyrin as an immune checkpoint inhibitor shows therapeutic efficacy in preclinical models of cancer

artículo científico publicado en 2018

Responses of human T cells to peptides flanking the tandem repeat and overlapping the signal sequence of MUC1

artículo científico publicado en 2005

Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.

artículo científico publicado en 2011

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

artículo científico publicado en 2016

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3

artículo científico publicado en 1997

Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type 1 responses.

artículo científico publicado en 2007

T cells reactive with HLA‐A*0201 peptides from the histone demethylase JARID1B are found in the circulation of breast cancer patients ⬇️

artículo científico publicado el 11 de febrero de 2011

Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment

artículo científico publicado en 2000

Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas.

artículo científico publicado en 2014

Targeting of Tumor-Associated Glycoforms of MUC1 with CAR T Cells

artículo científico publicado en 2016

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

artículo científico publicado en 2015

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

artículo científico publicado en 2005

The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9.

artículo científico publicado en 2016

The polymorphic epithelial mucin as a target for immunotherapy

artículo científico publicado en 1993

The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail

artículo científico publicado en 1992

The role of tumor-associated antigens in the biology and immunotherapy of breast cancer.

artículo científico publicado en 1993

Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions

artículo científico publicado en 2018

Transforming growth factor-β1 is constitutively secreted by Chinese hamster ovary cells and is functional in human cells.

artículo científico publicado en 2011

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

artículo científico publicado en 2007

Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer

artículo científico publicado en 2016

Lista de obras de Joy M Burchell

A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4 transferase.

A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas

A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes

An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas

Androgen-dependent synthesis of basic secretory proteins by the rat seminal vesicle ⬇️

Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells.

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis.

Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases

Breast carcinoma cell lysate-pulsed dendritic cells cross-prime MUC1-specific CD8+ T cells identified by peptide-MHC-class-I tetramers.

Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case–control study of colorectal cancer in UK collaborative trial of ovarian cancer screening

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer

Characterizing the glycome of the mammalian immune system.

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer

Differential effect of interferon on DNA synthesis, 2-deoxyglucose uptake and ornithine decarboxylase activity in 3T3 cells stimulated by polypeptide growth factors and tumor promotors.

Effective immunotherapy of cancer in MUC1-transgenic mice using clonal cytotoxic T lymphocytes directed against an immunodominant MUC1 epitope.

Effects of Testosterone on Sequence Complexity of Polyadenylated RNA from Rat Seminal Vesicle ⬇️

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma.

Functional analysis of the transcription repressor PLU-1/JARID1B.

Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells

HMFG1 antigen: a new marker for carcinomatous meningitis

Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.

Immunisation with 'naïve' syngeneic dendritic cells protects mice from tumour challenge.

Immunological analysis of mucin molecules expressed by normal and malignant mammary epithelial cells

Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers

Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.

Intramuscular immunisation with MUC1 cDNA can protect C57 mice challenged with MUC1-expressing syngeneic mouse tumour cells

JARID1/KDM5 demethylases as cancer targets?

Lack of beta-casein production by human breast tumours revealed by monoclonal antibodies

Latest developments in MUC1 immunotherapy.

MUC1 immunotherapy.

Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

Microvesicle cargo of tumor-associated MUC1 to dendritic cells allows cross-presentation and specific carbohydrate processing.

Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule

Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: Production and reaction with cells in culture

NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3.

O-linked glycosylation in the mammary gland: changes that occur during malignancy.

O-linked mucin-type glycosylation in breast cancer

PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?

PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis.

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells ⬇️

Production and characterization of monoclonal antibodies to human casein. A monoclonal antibody that cross-reacts with casein and alpha-lactalbumin

Radioimmunoscintigraphy of ovarian tumors using a new monoclonal antibody, SM-3

Radioimmunoscintigraphy with technetium-99m-labelled monoclonal antibody, SM3, in gynaecological cancer

Repurposing tin mesoporphyrin as an immune checkpoint inhibitor shows therapeutic efficacy in preclinical models of cancer

Responses of human T cells to peptides flanking the tandem repeat and overlapping the signal sequence of MUC1

Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3

Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type 1 responses.

T cells reactive with HLA‐A*0201 peptides from the histone demethylase JARID1B are found in the circulation of breast cancer patients ⬇️

Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment

Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas.

Targeting of Tumor-Associated Glycoforms of MUC1 with CAR T Cells

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9.

The polymorphic epithelial mucin as a target for immunotherapy

The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail

The role of tumor-associated antigens in the biology and immunotherapy of breast cancer.

Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions

Transforming growth factor-β1 is constitutively secreted by Chinese hamster ovary cells and is functional in human cells.

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer