Lista de obras -

A guide to modern quantitative fluorescent western blotting with troubleshooting strategies

artículo científico publicado en 2014

A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton

artículo científico publicado en 2014

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

artículo científico publicado en 2019

Analysis of gene expression in the nervous system identifies key genes and novel candidates for health and disease

artículo científico

ApoE isoform-specific regulation of regeneration in the peripheral nervous system

artículo científico publicado en 2011

Applying modern Omic technologies to the Neuronal Ceroid Lipofuscinoses

scientific article published on 15 June 2019

Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy.

artículo científico publicado en 2017

Bridging the gap: large animal models in neurodegenerative research

artículo científico publicado en 2017

Cellular and Molecular Anatomy of the Human Neuromuscular Junction

artículo científico publicado en 2017

Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo

artículo científico publicado en 2012

Commonality amid diversity: Multi-study proteomic identification of conserved disease mechanisms in spinal muscular atrophy

artículo científico publicado en 2016

Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion

artículo científico publicado en 2006

Density, calibre and ramification of muscle capillaries are altered in a mouse model of severe spinal muscular atrophy.

artículo científico publicado en 2011

Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene.

artículo científico publicado en 2007

Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene

artículo científico publicado en 2007

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

scientific article published on 03 March 2014

Equine grass sickness, but not botulism, causes autonomic and enteric neurodegeneration and increases soluble N-ethylmaleimide-sensitive factor attachment receptor protein expression within neuronal perikarya.

artículo científico publicado en 2015

Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues

artículo científico publicado en 2009

Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target

scientific article published on 01 December 2014

Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research

artículo científico publicado en 2011

Label-Free Quantitative Proteomic Profiling Identifies Disruption of Ubiquitin Homeostasis As a Key Driver of Schwann Cell Defects in Spinal Muscular Atrophy

scientific article published on 29 August 2014

Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy

artículo científico publicado en 2013

Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

artículo científico publicado en 2014

Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology

artículo científico publicado en 2008

Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).

artículo científico publicado en 2008

Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration

artículo científico publicado en 2017

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

scientific article published on 29 July 2009

Molecular neuropathology of the synapse in sheep with CLN5 Batten disease

artículo científico publicado en 2015

Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.

artículo científico publicado en 2017

Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation

artículo científico publicado en 2004

Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2

artículo científico publicado en 2009

Proteomic Profiling of Cranial (Superior) Cervical Ganglia Reveals Beta-Amyloid and Ubiquitin Proteasome System Perturbations in an Equine Multiple System Neuropathy

artículo científico publicado en 2015

Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo

artículo científico publicado en 2017

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture.

artículo científico publicado en 2017

Quantitative imaging of tissue sections using infrared scanning technology

artículo científico publicado en 2015

Regional Molecular Mapping of Primate Synapses during Normal Healthy Aging

artículo científico publicado en 2019

Reversible molecular pathology of skeletal muscle in spinal muscular atrophy

scientific article published on 12 August 2011

SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy

artículo científico publicado en 2010

Sideroflexin 3 is an α-synuclein-dependent mitochondrial protein that regulates synaptic morphology

artículo científico

Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose

artículo científico publicado en 2010

Synaptic vulnerability in neurodegenerative disease

artículo científico publicado en 2006

Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy

artículo científico publicado en 2016

The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells

artículo científico publicado en 2006

The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry

artículo científico publicado en 2014

Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting

artículo científico publicado en 2013

UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy

artículo científico publicado en 2018

Understanding the molecular consequences of inherited muscular dystrophies: advancements through proteomic experimentation.

artículo científico publicado en 2016

Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?

artículo científico

VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).

artículo científico publicado en 2008

WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering

artículo científico publicado en 2012

Lista de obras de

A guide to modern quantitative fluorescent western blotting with troubleshooting strategies

A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

Analysis of gene expression in the nervous system identifies key genes and novel candidates for health and disease

ApoE isoform-specific regulation of regeneration in the peripheral nervous system

Applying modern Omic technologies to the Neuronal Ceroid Lipofuscinoses

Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy.

Bridging the gap: large animal models in neurodegenerative research

Cellular and Molecular Anatomy of the Human Neuromuscular Junction

Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo

Commonality amid diversity: Multi-study proteomic identification of conserved disease mechanisms in spinal muscular atrophy

Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion

Density, calibre and ramification of muscle capillaries are altered in a mouse model of severe spinal muscular atrophy.

Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene.

Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Equine grass sickness, but not botulism, causes autonomic and enteric neurodegeneration and increases soluble N-ethylmaleimide-sensitive factor attachment receptor protein expression within neuronal perikarya.

Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues

Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target

Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research

Label-Free Quantitative Proteomic Profiling Identifies Disruption of Ubiquitin Homeostasis As a Key Driver of Schwann Cell Defects in Spinal Muscular Atrophy

Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy

Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology

Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).

Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

Molecular neuropathology of the synapse in sheep with CLN5 Batten disease

Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.

Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation

Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2

Proteomic Profiling of Cranial (Superior) Cervical Ganglia Reveals Beta-Amyloid and Ubiquitin Proteasome System Perturbations in an Equine Multiple System Neuropathy

Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture.

Quantitative imaging of tissue sections using infrared scanning technology

Regional Molecular Mapping of Primate Synapses during Normal Healthy Aging

Reversible molecular pathology of skeletal muscle in spinal muscular atrophy

SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy

Sideroflexin 3 is an α-synuclein-dependent mitochondrial protein that regulates synaptic morphology

Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose

Synaptic vulnerability in neurodegenerative disease

Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy

The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells

The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry

Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting

UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy

Understanding the molecular consequences of inherited muscular dystrophies: advancements through proteomic experimentation.

Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?

VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).

WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering